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1441
Effects of Dietary Aflatoxin B1 on Hybrid Grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂) Growth, Intestinal Health, and Muscle Quality
Published 2024-01-01“…In conclusion, diets with AFB1 levels exceeding 30 μg kg−1 inhibited hybrid grouper growth, while levels surpassing 445 μg kg−1 resulted in hindgut ROS accumulation, inflammation, elevated intestinal permeability, reduced digestive enzyme activity, and compromised muscle quality.…”
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1442
The use of Kutikulin for treatment and prevention of gastrointestinal diseases in calves and piglets
Published 2022-06-01“…The paper presents the results of tests of Kutikulin, a product made at the Vologda Branch of the FSC VIEV, which consists of chicken gizzard cuticle containing a keratoid secretion and a number of biologically active enzymes. It is a non-toxic, water-insoluble, odourless yellow-green powder with a bitterish taste. …”
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1443
Selenium’s Role in Plant Secondary Metabolism: Regulation and Mechanistic Insights
Published 2024-12-01“…Although it has been shown that selenium can affect the antioxidant system and defense mechanisms in plants, detailed mechanisms of selenium’s action on plant secondary metabolic pathways, including its effects on specific metabolic enzymes and regulatory genes, still need to be revealed by further in-depth studies. …”
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1444
<i>Cuphea hookeriana</i>: Phytochemical Profile and the Cosmeceutical and Dermatological Properties of Its Active Fraction from the Whole Plant
Published 2025-01-01“…It inhibited the two target enzymes (tyrosinase and MMP-1) engaged in skin whitening and aging with comparable IC<sub>50</sub> values to the reference drugs. …”
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1445
Clove oil as a neuromodulator in environmental cadmium cognitive impairment on the prefrontal cortex of Wistar rats
Published 2025-03-01“…The estimated GST, GPx, GSH, and GOT enzymes were by blood sample. Results: GSH and GST levels significantly decreased in the untreated but increased in the treated groups at P < 0.05. …”
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1446
The Effect of Lysophosphatidic Acid during In Vitro Maturation of Bovine Oocytes: Embryonic Development and mRNA Abundances of Genes Involved in Apoptosis and Oocyte Competence
Published 2014-01-01“…We found transcription of genes coding for enzymes of LPA synthesis pathway (ATX and PLA2) and of LPA receptors (LPAR 1–4) in bovine oocytes and cumulus cells, following in vitro maturation. …”
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1447
Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion
Published 2018-01-01“…To get an insight into the mechanism underlying the impaired melatonin secretion in SDT fatty rats, the expression of arylalkylamine N-acetyltransferase (Aanat) and acetylserotonin O-methyltransferase (Asmt) mRNA, which encode the rate-limiting enzymes for melatonin synthesis, was investigated in the pineal gland. …”
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1448
Fate and Effect of Intravenously Infused Mesenchymal Stem Cells in a Mouse Model of Hepatic Ischemia Reperfusion Injury and Resection
Published 2016-01-01“…Liver damage was evaluated by liver enzymes, histology, and inflammatory markers. Regeneration was determined by liver/body weight ratio, proliferating hepatocytes, and TGF-β levels. …”
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1449
Increased NOX-dependent ROS production and proportionally enhanced antioxidant response in white adipose tissue of male rats
Published 2025-01-01“…Materials and methods: The study analyzed the activity and gene expression of the antioxidant enzymes superoxide dismutase, catalase, and glutathione peroxidase, along with the production of NADPH oxidases dependent on H2O2 and gene expression of NOX1, NOX2, and NOX4. …”
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1450
CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3
Published 2025-01-01“…The enzymatic isomerization of at-ROL, crucial for restoring the visual pigments and preparing them to receive new light stimuli, relies on various enzymes found in both the photoreceptors and retinal pigment epithelium cells. …”
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1451
Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling
Published 2013-01-01“…Matrix metalloproteinases (MMPs), well-known inflammatory mediators are a family of zinc-dependent proteolytic enzymes that degrade various components of ECM and non-ECM molecules mediating tissue remodeling in both physiological and pathological processes. …”
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1452
Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats
Published 2013-01-01“…It can be proposed that the overexpression of these enzymes could be a mechanism of enhancement of hepatocytes tolerance to oxidative stress.…”
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1453
MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma
Published 2025-01-01“…Abstract Cholesterol metabolism is abnormally active in tumour cells. Metabolic enzymes related to cholesterol metabolism are upregulated in tumours, but their nonmetabolic functions remain unclear. …”
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1454
Exogenous nitric oxide relieves iron-inhibitory effect on wheat seed germination
Published 2025-02-01“…Changes in endogenous NO production, Fe content, starch mobilisation, and antioxidant enzyme activity were examined at the early (24 h) and late (72 h) germination stages. …”
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1455
Effects of Bile Acids on Growth Performance, Hepatopancreatic Antioxidant Capacity, Intestinal Immune-Related Gene Expression, and Gut Microbiota of <i>Penaeus vannamei</i>
Published 2025-01-01“…Furthermore, BA supplementation increased the activity of antioxidant-related enzymes in the hepatopancreas and enhanced the mRNA expression levels of gut-associated immune genes. …”
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1456
Methionine-induced regulation of growth, secondary metabolites and oxidative defense system in sunflower (Helianthus annuus L.) plants subjected to water deficit stress.
Published 2021-01-01“…Although, exogenously applied Met was effective in decreasing RMP, MDA and H2O2 contents, it increased the shoot fresh weight, shoot length, chlorophyll a, chlorophyll a/b ratio, proline contents and the activities of SOD, POD and CAT enzymes in all four cultivars under water deficit stress. …”
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1457
Mild Clinical Course of Severe Fever with Thrombocytopenia Syndrome Virus Infection in an Elderly Japanese Patient
Published 2014-01-01“…Laboratory data revealed thrombocytopenia, leukocytopenia, and elevated liver enzymes. She was then referred to our hospital. Although not completely fulfilling the diagnostic criteria used in a retrospective study in Japan, SFTS was suspected, and we detected SFTS virus in the patient’s blood using RT-PCR. …”
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1458
Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia
Published 2009-01-01“…They were evaluated clinically for the occurrence of complications and by the laboratory parameters (blood levels of glutathione peroxidase (Glu.PX) antioxidant enzyme, malondialdehyde (MDA), tumor necrosis factor-𝛼 (TNF-𝛼), liver enzymes, and bone marrow picture). …”
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1459
N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models
Published 2018-01-01“…Gene expression analyses of HepG2 cells reveal that n-3 PUFAs reduce the expression of genes involved in BA synthesis (CYP7A1, CYP27A1) and uptake (NTCP), while activating genes encoding metabolic enzymes (SULT2A1) and excretion transporters (MRP2, MRP3). …”
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1460
Colada morada, a traditional Ecuadorian Day of the dead beverage: Bibliometric analysis and review of the biological activity of native Ecuadorian ingredients
Published 2025-03-01“…Using bibliometric analysis and document reviews, we identified major bioactive compounds such as phenolic acids, anthocyanins, flavonoids, terpenoids, and proteolytic enzymes, which exhibit antioxidant, antimicrobial, anti-inflammatory, and chemopreventive properties. …”
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