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1241
Protective Effect of Commercial Grade Vitamin C against Alcohol-induced Testicular Damage in Male Wistar Rats
Published 2023-04-01“…Sperm motility, morphology, viability and antioxidant enzyme activity, but increase in the level of lipid peroxidation. …”
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1242
The Stability of a Model Substrate for Topoisomerase 1-Mediated DNA Religation Depends on the Presence of Mismatched Base Pairs
Published 2011-01-01“…Topoisomerase 1 (Top1) enzymes regulate DNA superhelicity by forming covalent cleavage complexes that undergo controlled rotation. …”
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1243
A Possible Novel Anti-Inflammatory Mechanism for the Pharmacological Prolyl Hydroxylase Inhibitor 3,4-Dihydroxybenzoate: Implications for Use as a Therapeutic for Parkinson’s Disea...
Published 2012-01-01“…Previously we demonstrated that pharmacological inhibition of a class of enzymes known as prolyl hydroxylases via 3,4-dihydroxybenzoate administration protected against MPTP-induced neurotoxicity, however the exact mechanisms involved were not elucidated. …”
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1244
Dyslipidemia and Fatty Liver Disease in Overweight and Obese Children
Published 2018-01-01“…Fasting lipid, liver transaminases, and ultrasound scans (US) for those with elevated enzymes were performed. Descriptive statistics were used for quantitative parameters. …”
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1245
CAPS markers in plant biology
Published 2015-07-01“…CAPS markers are based on PCR amplification of DNA fragments with specific primers followed by digestion with restriction enzymes and separation of the products in agarose gel. …”
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1246
The domestication and the brain: forty years after
Published 2017-07-01“…Higher concentration of 5-HT and its metabolite, 5-hydroxyindoleacetic acid, increased activity of the principle enzyme in 5-HT synthesis (tryptophan hydroxylase-2) and decreased activity of the principle enzyme in 5-HT degradation (monoamine oxidase A) was shown in the midbrain of domesticated silver foxes and rats. …”
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1247
Dysmorphic Facial Features and Other Clinical Characteristics in Two Patients with PEX1 Gene Mutations
Published 2016-01-01“…Case II was 2.5-year-old girl referred for investigation of global developmental delay and elevated liver enzymes. Ophthalmologic examination findings were consistent with bilateral nystagmus and retinitis pigmentosa. …”
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1248
Regulation of modular Cyclin and CDK feedback loops by an E2F transcriptionoscillator in the mammalian cell cycle
Published 2011-03-01“…The cell cycle is regulated by a large number of enzymes and transcription factors. We have developed a modular description of the cell cycle, based on a set of interleaved modular feedback loops, each leading to a cyclic behavior. …”
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1249
Surgical Removal of a Canine Aortic Thromboembolism Secondary to Pancreatitis
Published 2015-01-01“…Clinicopathologic analysis revealed increased muscle enzymes and proteinuria. Abdominal ultrasonography confirmed aortic thromboembolism (ATE), and surgical histopathology diagnosed necrotizing pancreatitis. …”
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1250
Silver Nanoparticles in Antifungal Applications: A Comparison of Biosynthesized and Physical Synthesized Nanoparticles on Paper-Biodegrading Fungi
Published 2024-11-01“…Background: Paper substrates are highly susceptible to fungal degradation, as fungi produce enzymes that decompose paper materials. This study investigates and compares the antifungal efficacy of silver nanoparticles (AgNPs) synthesized through various physical and biological methods. …”
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1251
Angiogenesis in Spontaneous Tumors and Implications for Comparative Tumor Biology
Published 2014-01-01“…Several molecules such as cell surface receptors, growth factors, and enzymes are involved in this process. While antiangiogenic therapy for cancer has been proposed over 20 years ago, it has garnered much controversy in recent years within the scientific community. …”
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1252
Thymol maintains peppers quality by regulating antioxidant capacity, cell wall metabolism and membrane lipid metabolism
Published 2025-01-01“…Additionally, thymol application inhibited the hydrolysis of pepper cell wall components and decreased the activities of enzymes related to cell wall and membrane lipid metabolism. …”
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1253
A Case of Reverse Takotsubo Cardiomyopathy Incited by a Spinal Subdural Hematoma
Published 2019-01-01“…It mimics myocardial infarction clinically and includes elevated cardiac enzymes, but echocardiography reveals apical ballooning and basal hyperkinesis. …”
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1254
Molecular Circuits of Resolution in the Eye
Published 2010-01-01“…A rapidly emerging field has identified key biosynthetic enzymes, receptors, and temporally defined endogenous formation of ω-3– and ω-6–derived protective lipid circuits in the eye. …”
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1255
Research Progress on Nutritional Characteristics, Taste Quality Improvement and Functional Evaluation of Germinated Brown Rice
Published 2025-01-01“…It also summarizes and analyzes the current status of research on stress enrichment of γ-aminobutyric acid (GABA) and functional characteristics of GBR. During germination, enzymes promote the enrichment of various bioactive substances, especially GABA, a characteristic component. …”
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1256
Morphological and Molecular Characteristics of Endophytic Fungi in Sugarcane as Antagonists of the Pathogen Fusarium sacchari
Published 2025-01-01“…Inhibition tests were conducted through dual culture and volatile compound testing, as well as enzyme production. The research results obtained 38 endophytic fungal isolates from sugarcane plants that have the ability to inhibit the pathogen F. sacchari. …”
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1257
Conformational Dynamics of Mitochondrial Inorganic Pyrophosphatase hPPA2 and Its Changes Caused by Pathogenic Mutations
Published 2025-01-01“…Inorganic pyrophosphatases, or PPases, are ubiquitous enzymes whose activity is necessary for a large number of biosynthetic reactions. …”
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1258
Prolonged Serum Alanine Aminotransferase Elevation Associated with Isotretinoin Administration
Published 2019-01-01“…When oral isotretinoin was readministered for intractable facial acne 3 years later, liver enzymes remained normal throughout the course of therapy. …”
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1259
Therapy with Interleukin-22 Alleviates Hepatic Injury and Hemostasis Dysregulation in Rat Model of Acute Liver Failure
Published 2014-01-01“…The following parameters were investigated: (1) survival rate, (2) serum levels of liver function enzymes (aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP)), total bilirubin (TBILI), and total albumen (ALB), (3) blood clotting tests (prothrombin time (PT), activated partial thromboplastin time (aPTT), and fibrinogen level (FIB)) and white blood cells (WBCs), red blood cells (RBCs), and platelet counts, (4) hepatic levels of tumor necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2), and (5) liver histopathology. …”
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1260
Exploring the Effects of Imidacloprid on Liver Health and the Microbiome in Rats: A Comprehensive Study
Published 2024-12-01“…Morphological changes were related to disturbances in the activity of liver enzymes, reflecting deteriorating liver function with increased imidacloprid exposure. …”
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