Fabrication and Optimization of ChE/ChO/HRP-AuNPs/c-MWCNTs Based Silver Electrode for Determining Total Cholesterol in Serum by Kusum Lata, Vikas Dhull, Vikas Hooda

“…The developed method used three enzymes comprised of cholesterol esterase, cholesterol oxidase, and peroxidase for fabrication of amperometric biosensor in order to determine total cholesterol in serum samples. …”
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The S-Layer Glycome—Adding to the Sugar Coat of Bacteria by Robin Ristl, Kerstin Steiner, Kristof Zarschler, Sonja Zayni, Paul Messner, Christina Schäffer

“…X-ray crystallography experiments allowed first insights into the catalysis mechanism of selected enzymes. In the future, it will be exciting to fully exploit the S-layer glycome for glycoengineering purposes and to link it to the bacterial interactome.…”
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Ways to improve the gene pool of pigs of the Russian Federation by V. A. Bekenеv

“…The positive effect of breeding pigs in a closed mode in the form of a “line-population”, using such genetic markers as erythrocyte antigens, erythrocyte enzymes, lipoproteins, allowing intensifcation of the selection process, has been experimentally proved. …”
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Effect of Cannabis seeds on Some biomedical parameters in male rats by Karwan Anwar Hassan

“…Alkaline Phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT), creatinine and uric acid was done for estimating the effect of cannabis seeds on renal and liver function. Enzymes Alkaline phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT) as well as creatinine, uric acid and very low-density lipoprotein (VLDL) were not significantly (p<0.05) different in both groups. …”
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Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV by Anna K. Coussens, Adrian R. Martineau, Robert J. Wilkinson

“…Conversely, vitamin D can act to inhibit expression and secretion of a broad range of inflammatory mediators and matrix degrading enzymes driving immunopathology during active TB and antiretroviral- (ARV-) mediated immune reconstitution inflammatory syndrome (IRIS). …”
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Unseen Enemy: Mechanisms of Multidrug Antimicrobial Resistance in Gram-Negative ESKAPE Pathogens by Giedrė Valdonė Sakalauskienė, Lina Malcienė, Edgaras Stankevičius, Aurelija Radzevičienė

“…Key bacterial mechanisms contributing to resistance include limitations in drug uptake, production of antibiotic-degrading enzymes, alterations in drug target sites, and enhanced drug efflux systems. …”
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Differential Modulation of Annexin I Binding Sites on Monocytes and Neutrophils by H. S. Euzger, R. J. Flower, N. J. Goulding, M. Perretti

“…These binding sites are proteinaceous in nature and are sensitive to cleavage by the proteolytic enzymes trypsin, collagenase, elastase and cathepsin G. …”
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A High-Fat, High-Fructose Diet Induces Antioxidant Imbalance and Increases the Risk and Progression of Nonalcoholic Fatty Liver Disease in Mice by Kanokwan Jarukamjorn, Nattharat Jearapong, Charinya Pimson, Waranya Chatuphonprasert

“…In the present study, the effects of a high-fat, high-fructose diet (HFFD) on mRNA levels and activities of the antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were determined in mouse livers and brains. …”
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BACE1 Is Necessary for Experience-Dependent Homeostatic Synaptic Plasticity in Visual Cortex by Emily Petrus, Hey-Kyoung Lee

“…Similarly, physiological functions for β- and γ-secretases, the two key enzymes that produce Aβ by sequentially processing the amyloid precursor protein (APP), have been discovered over recent years. …”
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Inhibition of mutagenic activation of orthoaminoazotoluene increases its carcinogenicity for mouse liver by V. I. Kaledin, L. P. Ovchinnikova, S. I. Ilnitskaya, T. S. Morozkova, N. A. Popova

“…The results of our comparative study with ortho-aminoazotoluene and 3.4-benzopyrene are in contradiction with the genotoxic theory of carcinogenesis: both are similarly activated by mouse liver enzymes, but induce tumors in different tissues: the former, hepatocellular carcinomas and the latter, splenic lymphoma. …”
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Oxidative Stress in Diabetic Nephropathy with Early Chronic Kidney Disease by Alejandra Guillermina Miranda-Díaz, Leonardo Pazarín-Villaseñor, Francisco Gerardo Yanowsky-Escatell, Jorge Andrade-Sierra

“…The overproduction of ROS diminishes expression of the antioxidant enzymes (manganese superoxide dismutase, glutathione peroxidase, and catalase). …”
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Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion. by Francois Dao, Amadou Niangaly, Fanta Sogore, Mamadou Wague, Djeneba Dabitao, Siaka Goita, Aboubacrin S Hadara, Ousmaila Diakite, Mohamed Maiga, Fatoumata O Maiga, Chantal Cazevieille, Cecile Cassan, Arthur M Talman, Abdoulaye A Djimde, Alejandro Marin-Menendez, Laurent Dembélé

“…However, when RBCs were pre-treated with various enzymes (neuraminidase, trypsin, and chymotrypsin), we observed a significant reduction in P. malariae invasion, albeit not a complete blockade. …”
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Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress by Md. Yusuf Al-Amin, Amitav Lahiry, Rafia Ferdous, Md. Kamrul Hasan, Md. Abdul Kader, AHM Khurshid Alam, Zahangir Alam Saud, Md. Golam Sadik

“…Among the crude extract and its fractions, chloroform fraction exerted strong inhibition of acetylcholinesterase and butyrylcholinesterase enzymes with IC50 values of 40.06 and 18.78 µg/mL, respectively. …”
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Monosodium glutamate (MSG) exposure induced oxidative stress and disrupted testicular hormonal regulation, exacerbating reproductive dysfunction in male WISTAR rats by Adesua Emmanuel Ogunmokunwa, Babatunde Oluwaseun Ibitoye

“…Conversely, the activities of antioxidant enzymes (SOD, CAT, GSH, GPx) were significantly diminished, reflecting impaired antioxidant defences. …”
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Liver Injury Secondary to Anti-TNF-Alpha Therapy in Inflammatory Bowel Disease: A Case Series and Review of the Literature by Ravish Parekh, Nirmal Kaur

“…Liver biopsy was performed in all 3 patients, and evidence of portal inflammation was seen. Liver enzymes normalized after discontinuation of therapy in all patients, and no long term effects have been observed. …”
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FACS‐Sortable Triple Emulsion Picoreactors for Screening Reactions in Biphasic Environments by Samuel Thompson, Yanrong Zhang, Zijian Yang, Lisa Nichols, Polly M. Fordyce

“…These triple emulsion picoreactors have the potential for future screening bead‐encoded catalyst libraries, including enzymes such as lipases for biofuel production.…”
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N-Oxalylglycine-Conjugated Hyaluronic Acid as a Macromolecular Prodrug for Therapeutic Angiogenesis by Andrew H. DeMaria, Jeoung Soo Lee, Ken Webb

“…NOG was conjugated to HA by esterification, and release was significantly increased in the presence of degradative enzymes, esterase and hyaluronidase, compared to physiological buffer, confirming that the release of NOG is primarily enzymatically driven. …”
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Evaluation of Colorimetric BCA-Based Quantification of Hydrazide Groups on Magnetic Particles by Zuzana Svobodova, Barbora Jankovicova, Zdenek Plichta, Daniel Horak, Zuzana Bilkova

“…Magnetic micro- and nanoparticles (MPs) are considered to provide excellent solid support for many immunoanalytical and bioaffinity applications, particularly when they contain hydrazide groups available for site-specific immobilization of various glycoproteins, such as immunoglobulin G and enzymes. To prepare a highly active bioaffinity carrier with sufficient binding capacity, knowledge as to the type and concentration of functional groups used for ligand binding is crucial. …”
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Syndrome of Inappropriate Secretion of Antidiuretic Hormone Cholestasis and Pericardial Effusion Due to Brucellosis Infection: A Case Report by Ahmet Cumhur Dülger, Özgür Kemik, Aziz Sümer, Hüseyin Akdeniz, Mehmet Emin Küçükoğlu, Esra Turan Canbaz, Veyis Itik, Enver Aytemiz

“…In addition to cholestasis and elevated liver enzymes, euvolemic hyponatremia, hypouricemia, low plasma osmolality, and high urinary osmolality were also detected. …”
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Adenine, a key player in biology and medicinal chemistry by Fillion, Alexandra, Vichier-Guerre, Sophie, Arimondo, Paola Barbara

“…In addition of being one of the four nucleobases constituting DNA and RNA, adenine is also contained in many biological molecules (ATP, SAM, NAD, cAMP, coA ...) that have fundamental roles in the functioning of living systems, e.g. energy source, cofactors of enzymes and proteins. As such, the adenine has naturally become a privileged scaffold explored in medicinal chemistry for biomedical applications. …”
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