Streptomyces at the Heart of Several Sectors to Support Practical and Sustainable Applications: A Review by Oumaima Beroigui, Faouzi Errachidi

“…In biotechnology, these totipotent microorganisms produce enzymes widely used in several industries, generating considerable revenue. …”
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Clinical Report of Probable Catastrophic Antiphospholipid Syndrome in Pregnancy by Eryk Hakman, Sasha Mikhael

“…Laboratory evaluation demonstrated microangiopathic disease with hemolysis (confirmed on peripheral smear), elevated liver enzymes, and abnormal 24-hour urine protein with vital signs within the normal range. …”
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Production of Secretory Leucocyte Protease Inhibitor (SLPI) in Human Pancreatic β-Cells by Max Nyström, Magnus Bergenfeldt, Irena Ljungcrantz, Èsa Lindeheim, Kjell Ohlsson

“…Secretory leucocyte protease inhibitor (SLPI) is a potent inhibitor of granulocyte elastase and cathepsin G, and also an inhibitor of pancreatic enzymes like trypsin, chymotrypsin and pancreatic elastase. …”
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Development of Bullous Disease during Treatment of Pulmonary Marginal Zone B-Cell Lymphoma by S. Ansari, H. Dubaybo, E. Levi, B. A. Dubaybo

“…This complication is rare, has been reported only once before in a patient with concomitant amyloidosis, and may be related to activation of proteolytic enzymes by lymphoma cells or chemotherapeutic agents.…”
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Metabolic Analysis of the Mode of Action and Mode of Resistance for Novobiocin in Staphylococcus aureus by Weile Xie, Dan Luo, Zhe Wang

“…Targeting of bacterial gyrase, specifically the gyrB subunit, is a promising approach because of this enzyme’s essential role in bacterial DNA replication and its absence in higher eukaryotes. …”
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Perceptions of Poultry Farmers on the Use of Growth Enhancers in Poultry Production in Rivers State, Nigeria by Favour Alapu, Angela Emodi

“…Results revealed that farmers (90.0%) were aware of the use of growth enhancers and pelleting additives (64.1%), feeding enzymes 64.1%, and antibiotics (51.3%) were the major growth enhancers used by poultry farmers. …”
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Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview by Katia D’Ambrosio, Anna Di Fiore, Emma Langella

“…Human carbonic anhydrases (hCAs) have been recognized as suitable drug targets for this therapeutic approach. These enzymes play a key role in maintaining pH balance, ion transport, and fluid regulation across various tissues and organs and their dysregulation has been associated to a variety of human pathologies. …”
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Angelica acutiloba Kitagawa Extract Attenuates DSS-Induced Murine Colitis by Jong-Chan Jang, Kang Min Lee, Seong-Gyu Ko

“…Treatment improved the colonic mRNA expression of different inflammatory markers: cytokines, inducible enzymes, matrix metalloproteinases, and tight junction-related proteins. …”
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Investigation of metabolic features of glioblastoma tissue and the peritumoral environment using targeted metabolomics screening by LC-MS/MS and gene network analysis by N. V. Basov, A. V. Adamovskaya, A. D. Rogachev, E. V. Gaisler, P. S. Demenkov, T. V. Ivanisenko, A. S. Venzel, S. V. Mishinov, V. V. Stupak, S. V. Cheresiz, O. S. Oleshko, E. A. Butikova, A. E. Osechkova, Yu. S. Sotnikova, Y. V. Patrushev, A. S. Pozdnyakov, I. N. Lavrik, V. A. Ivanisenko, A. G. Pokrovsky

“…Notably, 119 out of the 294 proteins regulating the key enzymes of sphingolipid metabolism were associated with glioblastoma. …”
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An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein... by Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao

“…_E13-27, which have the oligosaccharide-degradation enzymes genes, including the GH10, GH13, GH43, GH95, and GH115 families. …”
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Structural basis of FpGalNase and its combination with FpGalNAcDeAc for efficient A-to-O blood group conversion by Meiling Zhou, Kaishan Luo, Chao Su, Yan Sun, Zuyan Huang, Shuo Ma, Xun Gao, Jiwei Wang, Chen Zhang, Pengcheng Han, Guoqiu Wu

“…However, the major obstacle to this strategy is the relatively low catalytic efficiency of the enzymes involved. In this study, we investigated two enzymes from Flavonifractor plautii, N-acetylgalactosamine deacetylase (FpGalNAcDeAc) and galactosaminidase (FpGalNase), which demonstrate synergistic activity in efficiently converting A-type RBCs to O-type. …”
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Combined induction by Cu(II) and veratrole enhances the degradation of high molecular weight polyaromatic hydrocarbons by Fusarium dlaminii ZH-H2 by Jiayuan Gao, Mingyue Qi, Xiaomin Wang, Xuan Feng, Jiahui Li, Guangwei Zhang, Shengdong Feng, Zhixin Yang, Guohui Ning

“…The combined CL treatment not only significantly stimulated Lip activity, but also induced the expression of genes coding for non-ligninolytic enzymes, which contributed to the degradation of PAHs. …”
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Effects of typical plant growth regulator chlormequat chloride on alkaloidal compounds in Corydalis yanhusuo and molecular mechanisms by Zixuan Du, Jiayin Cao, Jie Meng, Heng Zhou, Qing Hu, Ling Li, Yun Liao, Shui Miao, Wenting Li, Shen Ji, Tongshuai Wang

“…Transcriptomic analysis also facilitates the identification of differential genes and enzymes associated with alkaloid production between the two groups. …”
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Alleviating <i>Clostridium perfringens</i>-Induced Intestinal Lesions in Chickens Using the Xylanase <i>Cb</i>Xyn10C and Its Binary Cocktail with a Protease by Wenjing Zhang, Zhenzhen Hao, Daoxin Yang, Wangli Ji, Kairui Guo, Xianhua Sun, Shuai Wang, Shuyan Yang, Jianshuang Ma, Tong Wang, Huiying Luo, Bin Yao, Meiling Zhang, Yuan Wang, Huoqing Huang, Xiaoyun Su

“…Not unexpectedly, feeding enzymes influenced the abundance of <i>Lactobacillus</i> and <i>Butyricicoccus</i> bacteria in the intestine. …”
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FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression by GAO Yuan, HUANG Yulan, ZHAO Kun

“…Objective‍　‍To screen the targets related to the metabolic enzymes involved in the cholesterol synthesis pathway that inhibits the polarization of macrophages towards M1 phenotype, and verify the intervention effects and underlying mechanisms in colorectal cancer cells. …”
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Production of Arthrospira platensis algae to increase production efficiency and enhance immune system of grass carp, Ctenopharyngodon idella against Aeromonas hydrophila by Hossein Adineh

“…At the end of the test period, growth and nutritional performance, digestive enzyme activities, blood serum antibacterial activity against Aeromonas hydrophila bacteria, immune and antioxidant factors, and blood indices were measured. …”
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A Survey of Mycotoxin Contamination in Fermented Condiments and the Biological Methods for Its Reduction by WANG Lihui, FU Jinhui, LI Chaowei, ZHANG Li, XIA Xiaolong, LI Sitong, ZHANG Mengmei, CHEN Yinzhu, LIU Shuliang, HU Kaidi, ZHAO Ning, LI Qin, LI Jianlong

“…This article summarizes the current status of mycotoxin contamination in fermented condiments, with a focus on mycotoxin-degrading strains from different sources and mycotoxin-degrading enzymes in microbial cells in order to offer insights for reducing harmful fungi and mycotoxin contamination in fermentation condiments.…”
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Polyphenol Bioaccessibility and Sugar Reducing Capacity of Black, Green, and White Teas by Shelly Coe, Ann Fraser, Lisa Ryan

“…While a number of studies have investigated the quantity and type of polyphenols present in different tea samples, no study has reported the potential effect of digestive enzymes on the availability of tea polyphenols for human absorption or the subsequent impact on glycaemic response. …”
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AIDS Cholangiopathy in an Asymptomatic, Previously Undiagnosed Late-Stage HIV-Positive Patient from Kenya by Yiming Gao, Kathryn Chin, Yehia Y. Mishriki

“…Routine laboratory testing was notable for a hypochromic microcytic anemia, slight leukopenia, and mild hypoalbuminemia. Liver enzymes were all elevated. Deep venous thrombosis was confirmed, and a CT scan of the chest disclosed no pulmonary emboli. …”
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Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation by Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin Rittinger

“…Abstract Deubiquitinating enzymes (DUBs) are key regulators of cellular homoeostasis, and their dysregulation is associated with several human diseases. …”
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