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1021
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2
Published 2025-02-01“…Results We find that analysis of circulating pancreatic enzymes aid the stratification of patients according to COVID-19 severity and predicts outcomes. …”
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1022
Colonic Necrosis in a 4-Year-Old with Hyperlipidemic Acute Pancreatitis
Published 2016-01-01“…This colonic complication was secondary to the extension of a large peripancreatic fluid collection causing direct serosal autodigestion by pancreatic enzymes. Two weeks following the initial presentation, the peripancreatic fluid collection developed into a mature pancreatic pseudocyst, which was percutaneously drained. …”
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1023
Epigenetics and Shared Molecular Processes in the Regeneration of Complex Structures
Published 2016-01-01“…This review provides an overview of known contributions to regenerative processes by noncoding RNAs and chromatin-modifying enzymes involved in epigenetic regulation.…”
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1024
Expression of Four Methionine Sulfoxide Reductases in Staphylococcus aureus
Published 2012-01-01“…Staphylococcus aureus possesses three MsrA enzymes (MsrA1, MsrA2, MsrA3) that reduce the S-epimer of methionine sulfoxide (MetO) and an MsrB enzyme that reduces R-MetO. …”
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1025
Prokaryotic cellulase gene clusters derived from 2,305 metagenomes
Published 2025-02-01“…They do it by producing cellulases, the various enzymes which break beta-glycosidic bonds in the cellulose. …”
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1026
Pantoprazole – safety in drug-drug interaction
Published 2012-09-01“…Pantoprazole is metabolized by CYP2C19 and CYP3A4, however, it has the lowest affinity to these enzymes of all PPIs. The primary metabolite of pantoprazole (the CYP system product 4-hydroxypantoprazole) enters next cytosolic phase of biotransformation i.e. conjugation to sulfate. …”
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1027
The Neurometabolic Function of the Dopamine–Aminotransferase System
Published 2025-01-01“…Results: The dopamine–aminotransferase system of the energy metabolism regulation is a separate, independent, regulatory and diagnostically significant biochemical pathway controlled by the hormonal system, the key hormone is cortisol, the key neurotransmitter is dopamine, the key transcription factor is CREB, and the key regulatory enzymes are alanine aminotransferase, aspartate aminotransferase, and tyrosine aminotransferase. …”
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1028
Exploring Marine Cyanobacteria for Lead Compounds of Pharmaceutical Importance
Published 2012-01-01“…They produce a large variety of bioactive compounds, including substances with anticancer and antiviral activity, UV protectants, specific inhibitors of enzymes, and potent hepatotoxins and neurotoxins. …”
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1029
Determination of lipid peroxidation biomarkers in vero cell line inoculated with bovine ephemeral fever virus
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1030
Hypertrophic Cardiomyopathy Mimicking Acute Anterior Myocardial Infarction Associated with Sudden Cardiac Death
Published 2012-01-01“…The patient presented with acute ST elevation myocardial infarction and significant elevation of cardiac enzymes. Cardiac catheterization showed some atherosclerotic coronary artery disease, without significant stenosis. …”
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1031
Biosynthesis and Role of N-Linked Glycosylation in Cell Surface Structures of Archaea with a Focus on Flagella and S Layers
Published 2010-01-01“…These include many of the glycosyltransferases and the oligosaccharyltransferase needed to assemble the glycans as well as some of the genes encoding enzymes required for the biosynthesis of the sugars themselves. …”
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1032
Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold
Published 2013-01-01“…PEA is synthesized and metabolized in animal cells via a number of enzymes and exerts a multitude of physiological functions related to metabolic homeostasis. …”
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1033
The Low Temperature Induced Physiological Responses of Avena nuda L., a Cold-Tolerant Plant Species
Published 2013-01-01“…Cold stress also leads to changes of some protected enzymes such as peroxidase (POD), superoxide dismutase (SOD), and catalase (CAT). …”
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1034
Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer
Published 2006-01-01“…<emph>Results</emph>. (1) The spatial distribution of the three leading enzymes in arachidonic acid pathway—cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1—followed sequential arrangement in Crohn's ulcer: neutrophils highly expressing 5-lipoxygenase were in the utmost surface which bordered the band of cyclooxygenase-2 expression that is located just beneath it, and in the lower layers and below the granulation region were eosinophils carrying 15-lipoxygeanse-1. (2) Cyclooxygenase-2 and 15-Lipoxygenase-1-positive cells formed two barrier-like structures that possibly inhibited neutrophil infiltration. …”
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1035
Giant Water Bugs, Electric Light Bugs, Lethocerus, Abedus, Belostoma (Insecta: Heteroptera: Belostomatidae)
Published 2005-02-01“…Individuals prey on aquatic insects, small fish, frogs, tadpoles, small birds, and other organisms they are able to capture. Powerful enzymes are injected into prey to kill them. Adults of Lethocerus are considered a delicacy in Asia, and are eaten both fresh and cooked. …”
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1036
Effects of Breakpoint Changes on Carbapenem Susceptibility Rates ofEnterobacteriaceae: Results from the SENTRY Antimicrobial Surveillance Program, United States, 2008 to 2012
Published 2014-01-01“…Very few of these Enterobacteriaceae produce carbapenamase enzymes; therefore, the clinical significance of these changes has not yet been clearly determined. …”
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1037
The state of the art in anti-aging: plant-based phytochemicals for skin care
Published 2025-01-01“…Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP-2) linked to aging. …”
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1038
Glycerol Carbonate: A Novel Biosolvent with Strong Ionizing and Dissociating Powers
Published 2012-01-01“…The activity of biocatalysts in nonaqueous solvents is related to the interaction of organic solvents with cells or enzymes. The behavior of proteins is strongly dependent on the protonation state of their ionizable groups, which ionization constants are greatly affected by the solvent. …”
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1039
Antimicrobial Activities of Stigmasterol from Piper crocatum In Vitro and In Silico
Published 2024-01-01“…The study findings indicate that the stigmasterol compound exhibits antibacterial and antifungal properties against pathogenic oral microorganisms in vitro as well as in silico against the crucial antibacterial enzymes MurA and PBP in addition to the pivotal antifungal enzyme exo-β-1,3-glucanase and lanosterol-14-α-demethylase. …”
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1040
Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
Published 2023-12-01“…Overall, the anti-aging properties of black pepper and its constituents are exhibited through several pathways, including senescence prevention, antioxidant protection, control of ROS levels, and the inhibition of aging-related enzymes. Additionally, cell cycle regulation, antiangiogenic and anti-metastatic action, apoptosis induction, and the suppression of carcinogenesis are some of the mechanisms utilized in cancer prevention activities. …”
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