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701
DNA Methylation: Its Role and Interaction with Epigenetic Modifications in Cancer
Published 2025-01-01“…DNA methylation is catalyzed by de novo and maintenance DNMT methyltransferase type enzymes and requires the transfer of a methyl group to cytosine to transform it into 5-methyl-cytosine. …”
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702
Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application
Published 2015-01-01“…Various clinical and in vivo studies have been undertaken to evaluate the effects of foods and food-derived components on the activity of detoxification pathways, including phase I cytochrome P450 enzymes, phase II conjugation enzymes, Nrf2 signaling, and metallothionein. …”
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703
Lipid Storage Myopathy in Behçet's Disease: A Rare Cause of Elevated Serum Creatine Kinases Levels
Published 2012-01-01“…The causes of elevated muscle enzymes in a patient with Behcet’s disease are many, including myositis, drug-induced myopathy, metabolic myopathy, and the disease itself. …”
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704
Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis
Published 2011-01-01“…When these yeasts are grown on methanol as the sole carbon and energy source, the enzymes involved in methanol metabolism are strongly induced, and the membrane-bound organelles, peroxisomes, which contain key enzymes of methanol metabolism, proliferate massively. …”
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705
Antibiotic Treatment of Dogs and Cats during Pregnancy
Published 2010-01-01“…The placenta functions as a barrier that protects the fetus due to the presence of transporters and metabolising enzymes; however, during pregnancy, the presence and activity of both enzymes and transporters may change. …”
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706
Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling
Published 2025-01-01“…The goal of this review is to present a comprehensive summary of the research on HA and its related receptors and enzymes in extracellular vesicle biogenesis and the cellular responses to vesicles bearing these extracellular matrix modulators. …”
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707
Improvement of Aspergillus niger for Sodium Gluconate Synthesis by UV Mutation Method
Published 2012-01-01“…A. niger was mutated with Ultraviolet (UV) radiation and the alteration of cell bound enzymes activity of gluconic acid synthesis pathway and sodium gluconate synthesis were evaluated. …”
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708
Glycosaminoglycan Storage Disorders: A Review
Published 2012-01-01“…There are eleven different enzymes involved in the stepwise degradation of GAGs. …”
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709
Diagnostics and treatment of exocrine pancreatic insufficiency: clinical guidelines of the Russian gastroenterological Association
Published 2018-08-01“…Exocrine pancreatic insufficiency (EPI) develops if activity of the enzymes in duodenal lumen in response to meal stimulation is insufficient to maintain normal nutrient digestion. …”
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710
Evaluating cutinase from Fusarium oxysporum as a biocatalyst for the degradation of nine synthetic polymer
Published 2025-01-01“…Our data demonstrate that bacterial cutinase enzymes have the same common ancestor as the PETase enzyme. …”
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711
Health promoting activities and corresponding mechanism of (–)-epicatechin-3-gallate
Published 2022-05-01“…Nontoxic ECG has various molecular targets within the cells, including CYP enzymes, phase II detoxification and antioxidant enzymes, as well as pro-inflammatory mediators. …”
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712
Organic Solvent Tolerant Lipases and Applications
Published 2014-01-01“…Lipases are a group of enzymes naturally endowed with the property of performing reactions in aqueous as well as organic solvents. …”
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713
Role of high-density lipoprotein cholesterol in health and diseases
Published 2021-01-01“…Although the exact mechanism still remains unelucidated, high-density lipoprotein cholesterol is a complex of lipids and proteins carrying many associated cargo molecules such as enzymes, signaling molecules, miRNA, which imparts overall functionality of high-density lipoprotein cholesterol for its beneficial health effects. …”
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714
Structure-Function of Falcipains: Malarial Cysteine Proteases
Published 2012-01-01“…The best characterized Plasmodium cysteine proteases are falcipains, which are papain family enzymes. Falcipain-2 and falcipain-3 are major hemoglobinases of P. falciparum. …”
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715
Glycogenic Hepatopathy in Type 1 Diabetes Mellitus
Published 2015-01-01“…This condition, characterized by elevated liver enzymes and hepatomegaly, is caused by irreversible and excessive accumulation of glycogen in hepatocytes. …”
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716
Adenosine Inhibits the Release of Arachidonic Acid in Activated Human Peripheral Mononuclear Cells. A Proposed Model for Physiologic and Pathologic Regulation in Systemic Lupus Ery...
Published 2011-01-01“…The AA production of monocytes mainly depends on two (IV and VI) types of PLA2 enzymes. PKCα phosphorylates the cytosolic, Ca2+-dependent and steroid-sensitive PLA2 (type IV), whereas PKCδ phosphorylates the Ca2+-independent PLA2 (type VI). …”
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717
The Role of Proteinase-Activated Receptors 1 and 2 in the Regulation of Periodontal Tissue Metabolism and Disease
Published 2017-01-01“…The mechanisms through which PARs can respond to periodontal enzymes and result in appropriate immune responses have until recently been poorly understood. …”
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718
Isolation and Identification of Lipase-producing Actinobacteria from the Lut Desert of Iran
Published 2024-09-01“…Lipases are the third category of widely used hydrolytic enzymes that catalyze the hydrolysis of triacylglycerols, glycerol, and free fatty acids. …”
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719
Comparative effects of pravastatin and rosuvastatin on carbohydrate metabolism in an experimental diabetic rat model
Published 2024-03-01“…Statin treatment may increase the risk of diabetes; there is insufficient data on how statins affect glucose regulation and glycemic control and the effects of statins on liver enzymes related to carbohydrate metabolism have not been fully studied. …”
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720
Efficient hydrogen peroxide reduction in glutathione peroxidase cycle using cost-effective FeSe2 nanospheres
Published 2025-01-01“…IntroductionHydrogen peroxide plays a crucial role in melanogenesis by regulating tyrosinase activity, the key melanin-forming enzyme responsible for the browning of fruits, vegetables, and seafood. …”
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