Comparative Studies on the Amylase and Cellulase Production of <i>Aspergillus</i> and <i>Penicillium</i> by Ibatsam Khokhar, Irum Mukhtar, Sobia Mushtaq

“…Filamentous fungi are important due to their high enzymes production potential. Many enzymes produced by fungi have related to biotechnological applications in several industrial sectors. …”
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Comparative Studies on the Amylase and Cellulase Production of <i>Aspergillus</i> and <i>Penicillium</i> by Ibatsam Khokhar, Irum Mukhtar, Sobia Mushtaq

“…Filamentous fungi are important due to their high enzymes production potential. Many enzymes produced by fungi have related to biotechnological applications in several industrial sectors. …”
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Adrenal Insufficiency as a Cause of Acute Liver Failure: A Case Report by Jamshid Vafaeimanesh, Mohammad Bagherzadeh, Mahmoud Parham

“…In the previously reported cases of adrenal insufficiency, mild liver enzymes elevation was seen but we report a case with severe elevated liver enzymes and liver failure due to adrenal insufficiency. …”
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Exploring the Bioaccessibility of Roasted Japanese Green Tea: Impact of Simulated Gastrointestinal Digestion by Wei Qin, Sunantha Ketnawa

“…Gastric conditions led to a 2.07-fold reduction in TPC and a 4.27-fold reduction in TFC. Digestive enzymes enhanced bioactive compound stability, with TPC and TFC bioaccessibility reaching 56% and 25% in the simulated digestion with digestive enzymes (MD) group, compared to 52% and 20% in the without digestive enzymes (WOE) group. …”
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Zymophagy: Selective Autophagy of Secretory Granules by Maria I. Vaccaro

“…That's especially true when it comes to the activation of enzymes created by the pancreas to break down food. …”
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Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics by Ibrahim El-Serafi, Sinclair Steele

“…Cyclophosphamide (Cy) is a prodrug that is mainly bioactivated by cytochrome P450 (CYP) 2B6 enzyme. Several other enzymes are also involved in its bioactivation and affect its kinetics. …”
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Genomic Analysis of a New Estrogen-Degrading Bacterial Strain, Acinetobacter sp. DSSKY-A-001 by Qing Qiu, Ping Wang, Hui Kang, Yu Wang, Kejian Tian, Hongliang Huo

“…Therefore, a total of nine enzymes related to estrogen degradation were found.…”
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Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD by Charles I. V. Drummer, Fatma Saaoud, Yu Sun, Diana Atar, Keman Xu, Yifan Lu, Ying Shao, Candice Johnson, Lu Liu, Huimin Shen, Nirag C. Jhala, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We performed a panoramic analysis on both human nonalcoholic steatohepatitis (NASH) microarray data and microarray/RNA-seq data from various mouse models of nonalcoholic fatty liver disease NASH/NAFLD with total 4249 genes examined and made the following findings: (i) human NASH and NAFLD mouse models upregulate both cytokines and chemokines; (ii) pathway analysis indicated that human NASH can be classified into metabolic and immune NASH; methionine- and choline-deficient (MCD)+high-fat diet (HFD), glycine N-methyltransferase deficient (GNMT-KO), methionine adenosyltransferase 1A deficient (MAT1A-KO), and HFCD (high-fat-cholesterol diet) can be classified into inflammatory, SAM accumulation, cholesterol/mevalonate, and LXR/RXR-fatty acid β-oxidation NAFLD, respectively; (iii) canonical and noncanonical inflammasomes play differential roles in the pathogenesis of NASH/NAFLD; (iv) trained immunity (TI) enzymes are significantly upregulated in NASH/NAFLD; HFCD upregulates TI enzymes more than cytokines, chemokines, and inflammasome regulators; (v) the MCD+HFD is a model with the upregulation of proinflammatory cytokines and canonical and noncanonical inflammasomes; however, the HFCD is a model with upregulation of TI enzymes and lipid peroxidation enzymes; and (vi) caspase-11 and caspase-1 act as upstream master regulators, which partially upregulate the expressions of cytokines, chemokines, canonical and noncanonical inflammasome pathway regulators, TI enzymes, and lipid peroxidation enzymes. …”
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Changes in Enzymatic Activity of Fish and Slaughter Animals Meat after High Pressure Treatment at Subzero Temperatures by Malinowska-Pańczyk Edyta, Kołodziejska Ilona

“…Proteolytic enzymes from salmon flesh were more resistant than those from cod flesh. …”
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Antitoxic Effects of Chicory Herb Extract Fractions in Rats with Toxic Hepatitis by I. A. Lupanova, O. L. Saybel, E. N. Kurmanova, E. V. Ferubko, I. A. Martynchik, P. G. Mizina

“…The changes in the activity of biotransformation enzymes (cytochrome P450 [cytР450] and glutathione transferase [GT]) in hepatocytes and serum liver enzymes (AST, ALT and AP) were assessed.Results. …”
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2-Cys Peroxiredoxins: Emerging Hubs Determining Redox Dependency of Mammalian Signaling Networks by Jinah Park, Sunmi Lee, Sanghyuk Lee, Sang Won Kang

“…Mammalian cells have a well-defined set of antioxidant enzymes, which includes superoxide dismutases, catalase, glutathione peroxidases, and peroxiredoxins. …”
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Epigenetics and Breast Cancers by An T. Vo, Richard M. Millis

“…This makes the chromatin accessible for transcription factors and enzymes.…”
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Bacterial Glycosulphatases and Sulphomucin Degradation by Anthony M Roberton, Damian P Wright

“…These enzymes remove part of the sulphate content from sulphomucins and make them more susceptible to further enzymic degradation. …”
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Organophosphorus Nerve Agents: Types, Toxicity, and Treatments by Sudisha Mukherjee, Rinkoo Devi Gupta

“…Organophosphorus compounds are reported to be the nonphysiological substrate for many mammalian organophosphate hydrolysing enzymes; therefore, the efficiency of these enzymes toward these compounds is inadequate. …”
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The Role of System-Specific Molecular Chaperones in the Maturation of Molybdoenzymes in Bacteria by Meina Neumann, Silke Leimkühler

“…This sulfur ligand is inserted into Moco while bound to the XdhC-like protein and before its insertion into the target enzyme. In addition, enzymes of the xanthine oxidase family bind either the molybdopterin (Mo-MPT) form of Moco or the modified molybdopterin cytosine dinucleotide cofactor (MCD). …”
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TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State by Simone Cardaci, Maria Rosa Ciriolo

“…Inborn defects of the tricarboxylic acid (TCA) cycle enzymes have been known for more than twenty years. …”
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Lipase and Its Unique Selectivity: A Mini-Review by Jun-Young Park, Kyung-Min Park

“…Contrary to other solid catalysts, enzymes facilitate more sophisticated chemical reactions because most enzymes specifically interact with substrates and release selective products. …”
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The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome by Chi-Hua Yen, Nae-Cherng Yang, Bor-Jen Lee, Jui-Yuan Lin, Simon Hsia, Ping-Ting Lin

“…The levels of antioxidant enzymes were significantly lower in the MS group than in the non-MS group. …”
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Agave Leaves as a Substrate for the Production of Cellulases by Penicillium sp. and the Obtainment of Reducing Sugars by Julio Silva-Mendoza, Alberto Gómez-Treviño, Ulrico López-Chuken, Edgar Allan Blanco-Gámez, Leonardo Chávez-Guerrero, María Elena Cantú-Cárdenas

“…The enzymes showed activities at elevated temperatures: 50°C for endoglucanase and exoglucanase and 70°C for β-glucosidase. …”
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A Refined Nomenclature System to Better Discriminate Endo- and Exo-Type Fructanases and Glucanases by Laura Leaerts, Jaime Ricardo Porras-Domínguez, Maxime Versluys, Wim Van den Ende

“…Distinguishing between endo- and exo-type enzymes within the glycoside hydrolase (GH) classification presents significant challenges. …”
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