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3441
The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars
Published 2020-01-01“…Fingolimod (FTY720) is an analog of S1P and thus functionally antagonizes S1P receptors and inhibits the enzyme that produces S1P. We examined the effects of topical FTY720 injections on mechanical force-induced HS progression. …”
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3442
Characterizations of cytokines and viral genomes in serum of patients with Dabie bandavirus infection
Published 2025-01-01“…The cytokine concentrations in serum were detected by micro enzyme-linked immunosorbent assay (ELISA). The genomes of Dabie bandavirus were amplified using a designated primer pool. …”
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3443
Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice
Published 2025-03-01“…At the end of the study hepatic Cyp2E1, an enzyme that metabolize AOM, was lower in males than females. …”
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3444
Role of the Btk-PLCγ2 Signaling Pathway in the Bone Destruction of Apical Periodontitis
Published 2019-01-01“…By silencing Btk, the expression of Btk, PLCγ2, and NFATc-1 was detected by real-time qPCR and Western blot, and osteoclastogenesis was detected by enzyme histochemical staining to further confirm the role of Btk in bone resorption. …”
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3445
Counteracting negative effects of salinity on Lepidium sativum L. seedlings by prepared biochar
Published 2024-10-01“…The use of prepared biochar at 0.5 and 1% reduced the damaging effects of salt stress by enhancing the activity of the α-amylase enzyme, resulting in a significant rise in germination (95% at 5000 mg/L by 0.5% of biochar). …”
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3446
Eating Habits, Anxiety and Depression in Patients with Irritable Bowel Syndrome: Clinical and Laboratory Comparisons
Published 2023-08-01“…All individuals included in the study were assessed for diet and eating habits using the WHO CINDI program questionnaire, “Information on Nutrition and Eating Behavior”, the severity of anxiety and depression according to the HADS questionnaire, the level of specific anxiety in relation to gastrointestinal symptoms according to the VSI questionnaire, quality of life according to the IBS-QoL questionnaire. In addition, the enzyme immunoassay method was used to assess the levels of cortisol in the morning and evening portions of saliva, serotonin in the blood serum and dopamine in the blood plasma.Results. …”
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3447
Molecular and serological investigation of hepatitis B virus in patients with acute undifferentiated febrile illness at Tha Song Yang hospital, Tak Province, Thailand
Published 2025-01-01“…The serum samples were subjected to enzyme-linked immunosorbent assay to detect antibodies against hepatitis B core antigen (HBcAg) and hepatitis B surface antigen (HBsAg). …”
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3448
Malyngamide F Possesses Anti-Inflammatory and Antinociceptive Activity in Rat Models of Inflammation
Published 2021-01-01“…Levels of TNF-α, PGE-2, and IL-6 were detected by enzyme-linked immunosorbent assay (ELISA). Results. …”
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3449
Korelasi Kadar Adiponektin dengan Indeks Aterogenik Plasma pada Penyandang Obes
Published 2020-11-01“…Pemeriksaan kadar adiponektin dengan metode enzyme linked immunoassay (ELISA). Pemeriksaan kolesterol high density lipoprotein (HDL) dan trigliserida menggunakan alat kimia klinik otomatis. …”
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3450
Hepatitis E virus infection among blood donors in Hangzhou
Published 2025-01-01“…[Methods] A total of 5 075 blood samples of blood donors from Zhejiang Provincial Blood Center from September to November 2023 were collected, including 5 037 samples with normal ALT and 38 samples with elevated ALT (>50 U/L). Enzyme-linked immunosorbent assay (ELISA) was used to detect anti-HEV IgM, anti-HEV IgG and HEV-Ag. …”
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3451
Lack of Intensity Control during an Exercise Program Is Related to a Limited Effect on Variables Responsible for Blood Pressure Regulation in Hypertensive Older Adults
Published 2024-01-01“…A significant improvement was observed in general functional fitness index (GFFI: p≤0.000, d = 0.35), nitrite (NO2−: p≤0.000, d = 0.49), systolic blood pressure (SBP: p≤0.000, d = 0.65), diastolic blood pressure (DBP: p≤0.013, d = 0.40), thiobarbituric acid reactive substances (TBARS: p≤0.007, d = 0.78), activity of the endothelial superoxide dismutase enzyme (ecSOD: p≤0.032, d = 0.41), double product (DP: p≤0.015, d = 0.43), and waist-hip ratio (WHR: p≤0.000, d = 0.44) for ICEP. …”
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3452
Hepatoprotective Effects of Nasturtium Officinale and Allium Polyanthum Extracts on CCL4- Induced Hepatic Damage In Albino Rats
Published 2022-01-01“…Results: CCl4-treated rats were showed significant increase (p < 0.05) in the levels of serum enzyme activities (AST, ALT, & ALP), TSB and MDA; reflecting the hepatocellular damage caused by CCl4 compared with NC rats, whereas the levels of TP and ALB were decreased. …”
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3453
Point Mutations in the folP Gene Partly Explain Sulfonamide Resistance of Streptococcus mutans
Published 2013-01-01“…The isolates were tested for resistance to cotrimoxazole and their folP DNA (which encodes sulfonamide-targeted enzyme dhps) cloned in pUC19. A set of recombinant plasmids carrying different point mutations in cloned folP were separately transformed into folP-deficient Escherichia coli. …”
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3454
Diospyros kaki and Citrus unshiu Mixture Improves Disorders of Lipid Metabolism in Nonalcoholic Fatty Liver Disease
Published 2020-01-01“…Continuously, the activation of PPARα significantly elevated carnitine palmitoyltransferase 1 (CPT-1), a key enzyme in fatty acid β-oxidation, and mitochondrial uncoupling protein 2 (UCP-2), thermogenic regulatory genes, in PCM-treated mice compared with those of HFD control mice. …”
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3455
Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV‐J Strain Isolated From Chinese Hetian Chickens
Published 2024-11-01“…Methods LY2021J was isolated using DF‐1 cells and validated by enzyme‐linked immunosorbent assay (ELISA) and IFA. …”
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3456
SSR loci potentially associated with high amylopectine content in maize kernel endosperm
Published 2018-09-01“…Mutations in the waxy gene, which break down the structure and function of the enzyme for amylose biosynthesis, lead to a waxy (with a high content of amylopectin) endosperm formation. …”
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3457
Cell-Specific Regulation of Inflammatory Cytokines and Acute-Phase Proteins by the Glucocorticoid Receptor
Published 2023-01-01“…Primary human hepatocytes (PHH) were treated with combinations of tumor necrosis factor alpha (TNFα), lipopolysaccharide (LPS), and dexamethasone (DEX) for 24 h, following which chemokine mRNA and protein expression were analyzed using qPCR and enzyme-linked immunosorbent assay assays. Dual luciferase assays were performed on transfected cell lines. …”
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3458
Aflatoxin B1: Challenges and Strategies for the Intestinal Microbiota and Intestinal Health of Monogastric Animals
Published 2025-01-01“…Mycotoxin-detoxifying agents include mycotoxin-adsorbing agents, such as clay and yeast cell wall compounds, binding to AFB<sub>1</sub> and mycotoxin-biotransforming agents, such as specific strains of <i>Bacillus subtilis</i> and mycotoxin-degrading enzyme, degrading AFB<sub>1</sub> into non-toxic metabolites such as aflatoxin D1. …”
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3459
miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure
Published 2025-01-01“…This decline in TREM2 expression was associated with increased proteolysis of TREM2 by a disintegrin and metalloproteases 10 (ADAM10) as well as a disintegrin and metalloproteases 17 (ADAM17), in which ADAM17 was verified as the main cleavage enzyme in terms of TREM2 proteolytic cleavage in hypertensive mice following Pb exposure. …”
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3460
Qingfei Tongluo Mixture Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis through mTOR-Dependent Autophagy in Rats
Published 2024-01-01“…Body weight and lung coefficient were examined, combined with hematoxylin and eosin (H&E) and Masson staining to observe lung tissue lesions. The enzyme-linked immunosorbent assay (ELISA) and the hydroxyproline (HYP) assay kit were used to detect changes in proinflammatory factors (transforming growth factor-β (TGF-β), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β)) and HYP. …”
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