Could serum Raftlin and GPER-1levels be new biomarkers for early detection of non-small cell lung cancer? by Aykut Eliçora, Berrak Güven, Hüseyin Engin, Gokcen Tugba Çevik, Hüseyin Fatih Sezer

“…GPER-1 and Raftlin levels were measured by Enzyme-Linked Immunosorbent Assay (ELISA) in blood samples taken from patients diagnosed with lung cancer and healthy volunteers. …”
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Evaluating Methods for Aflatoxin B1 Monitoring in Selected Food Crops Within Decentralized Agricultural Systems by Haadia Tanveer, Hannah Glesener, Blake Su, Brooke Bolsinger, Rosa Krajmalnik-Brown, Lee E. Voth-Gaeddert

“…The objectives of this study were: (1) to evaluate common AFB1 detection methods, including enzyme-linked immunosorbent assays (ELISA) and lateral-flow assays (LFA), validated via high-performance liquid chromatography (HPLC), focusing on their suitability for possible applications in decentralized, low-resource settings; and (2) to conduct a barriers-to-use assessment for commonly available AFB1 detection methods and their applicability in low-resource settings. …”
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Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres by Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

“…Furthermore, elution of rmIL-12 from IL-12-NS at a concentration of 500 million particles/mL was characterized using enzyme-linked immunosorbent assay (ELISA). When IL-12-NS was administered in vivo to female BALB/c mice through retroorbital injection, IL-12-NS produced a favorable systemic cytokine profile for tumoricidal activity within the peripheral blood. …”
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Tracheal Resection for Critical Airway Obstruction in Morquio A Syndrome by Claire Frauenfelder, Elizabeth Maughan, Johnny Kenth, Reema Nandi, Simon Jones, Robert Walker, Bill Walsh, Nagarajan Muthialu, Iain Bruce, Richard Hewitt, Colin Butler

“…The relative pathophysiological contributions of an inherent cartilage processing defect versus a mismatch in longitudinal growth between the trachea and the thoracic cage are currently a subject of debate. Enzyme replacement therapy (ERT) and multidisciplinary management continue to improve life expectancy for Morquio A patients by slowing many of the multisystem pathological consequences of the disease but are not as effective at reversing established pathology. …”
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P-glycoprotein and/or Histone Deacetylase 2 Regulates Steroid Responsiveness in Childhood Nephrotic Syndrome by Harshit Singh, Narayan Prasad, Durga Prasanna Misra, Akhilesh Kumar Jaiswal, Vikas Agarwal

“…Glucocorticoids suppress NFκB-associated coactivator activity by deacetylation of histone by enzyme histone deacetylase (HDAC)-2. Interaction between HDAC2 activity and P-gp expression in childhood NS patients is not clear. …”
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Association of AGTR1 A1166C and CYP2C9∗3 Gene Polymorphisms with the Antihypertensive Effect of Valsartan by Yi Liu, Xiaomu Kong, Yongwei Jiang, Meimei Zhao, Peng Gao, Xiao Cong, Yongtong Cao, Liang Ma

“…The present study aimed to investigate whether the antihypertensive effect of the ARB drug valsartan was associated with angiotensin II type 1 receptor (AGTR1) gene polymorphism (A1166 C) and cytochrome P450 enzyme 2C9 (CYP2C9) gene polymorphism (CYP2C9∗3). …”
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Perioperative Treatment with Rivaroxaban and Dabigatran on Changes of Coagulation and Platelet Activation Biomarkers following Left Atrial Appendage Closure by Yao Yao, Yanli Li, Qinchun Jin, Xiaoye Li, Xiaochun Zhang, Qianzhou Lv

“…The biochemical indicators, thrombin-antithrombin complex (TAT), soluble P-selectin (sP-selectin), von Willebrand factor (vWF), and CD40 ligand (CD40L), were measured by enzyme-linked immunosorbent assay. The primary endpoints of this study were the efficacy and safety characteristics of different antithrombotic strategies, including DRT incidence, stroke or transient ischemic attack, systemic embolism, and clinical major and nonmajor bleeding complications during the follow-up of 180 days. …”
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Clinical value of serum biomarkers, squamous cell carcinoma antigen and apolipoprotein C-II in follow-up of patients with locally advanced cervical squamous cell carcinoma treated... by Yoko Harima, Takuro Ariga, Yuko Kaneyasu, Hitoshi Ikushima, Sunao Tokumaru, Shigetoshi Shimamoto, Takeo Takahashi, Noriko Ii, Kayoko Tsujino, Anneyuko I Saito, Hiroki Ushijima, Takafumi Toita, Tatsuya Ohno

“…ApoC-II was measured using a monoclonal antibody-based enzyme-linked immunosorbent assay, which was developed for this purpose. …”
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Screening and Characterization of Thermostable Amylase-Producing Bacteria Isolated from Soil Samples of Afdera, Afar Region, and Molecular Detection of Amylase-Coding Gene by Semira Nureddin Yassin, Tamene Milkessa Jiru, Meera Indracanti

“…Studies on the effect of temperature revealed that the crude enzyme had a maximum activity and stability at 75°C, 70°C, and 65°C for isolates M13, M8, and M2, respectively. …”
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Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis by Toru Arai, Masaki Hirose, Yoshimasa Hamano, Tomoko Kagawa, Akihiro Murakami, Hiroshi Kida, Atsushi Kumanogoh, Yoshikazu Inoue

“…We measured anti-MX1 immunoglobulin (Ig) G, IgA, and IgM autoantibody levels by enzyme-linked immunosorbent assay in serum collected at the time of diagnosis from 71 patients with IPF diagnosed according to the 2018 IPF guideline. …”
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The Association between the Activin A Serum Level and Carotid Intima-Media Thickness in Chronic Kidney Disease Patients by Ade Yonata, Zulkhair Ali, Taufik Indrajaya, Erial Bahar, Ian Effendi, Novadian Suhaimi, Suprapti Suprapti

“…The level of activin A was measured by enzyme-linked immunosorbent assay. Meanwhile, cIMT measurements were collected by B-mode ultrasound imaging. …”
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Angiotensin receptor neprilysin inhibition versus individualized RAAS blockade: design and rationale of the PARALLAX trial by Rolf Wachter, Sanjiv J. Shah, Martin R. Cowie, Peter Szecsödy, Victor Shi, Ghionul Ibram, Ziqiang Zhao, Jianjian Gong, Sven Klebs, Burkert Pieske

“…In addition, no prior studies have compared sacubitril/valsartan with angiotensin‐converting enzyme inhibitor therapy. We sought to compare the effect of ARNI to background‐medication‐based individualized comparators (BMICs) on N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), functional capacity [6 min walk distance (6MWD)], symptoms, and quality of life [Kansas City Cardiomyopathy Questionnaire (KCCQ)] in patients with HF and EF >40% in a randomized clinical trial. …”
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Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury by Duraisamy Kempuraj, Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Ramasamy Thangavel, Sudhanshu P. Raikwar, Smita A. Zaheer, Shankar S. Iyer, Casey Burton, Donald James, Asgar Zaheer

“…We analyzed mast cell activation by toluidine blue staining, serum chemokine C-C motif ligand 2 (CCL2) level by enzyme-linked immunosorbent assay (ELISA), and proteinase-activated receptor-2 (PAR-2), a mast cell and inflammation-associated protein, vascular endothelial growth factor receptor 2 (VEGFR2), and blood-brain barrier tight junction-associated claudin 5 and Zonula occludens-1 (ZO-1) protein expression in the brains of TBI mice. …”
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Effects of Dietary Resveratrol, Bile Acids, Allicin, Betaine, and Inositol on Recovering the Lipid Metabolism Disorder in the Liver of Rare Minnow Gobiocypris rarus Caused by Bisph... by Yingying Zhang, Yinan Jiang, Ziying Wang, Jiayu Wang, Mingzhen Zhu, Hui Yang

“…In terms of lipid metabolism-related enzyme activity, bile acid and inositol were the most effective in recovering BPA-induced lipid metabolism disorders. …”
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Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome

“…Whole saliva from 30 patients with BMS, age range 55–65, was tested for the presence of IL-6 and IL-2 by enzyme immunoassay. Control group consisted of 30 healthy participants, aged 55–65 years. …”
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Growth and viability of juvenile humpback grouper (Cromileptes altivelis) supplemented with inorganic and organic selenium by Muhaimin Hamzah, Muhammad Agus Suprayudi, Nur Bambang Priyo Utomo, Wasmen Manalu

“…The results of this study showed that the source of selenium supplementation (inorganic or organic) affected growth performance, glutathione peroxidase (GPx) enzyme activity, and blood profiles of the experimental fish. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…Mutation of encoding gene — A (TA) 7TAA A is the principal cause of insufficiency of this enzyme, however development of clinical syndrome and severity of symptoms is related to other factors as well (male gender, additional genetic mutations, et al.). …”
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Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review. by Camille Fritzell, Dominique Rousset, Antoine Adde, Mirdad Kazanji, Maria D Van Kerkhove, Claude Flamand

“…Although several assays were used, enzyme-linked immunosorbent assays (ELISAs) were the predominant test used (77%). …”
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Resistance-breaking strains of tomato spotted wilt virus hamper photosynthesis and protein synthesis pathways in a virus accumulation-dependent manner in Sw5-carrying tomatoes by Maria Isabella Prigigallo, Ugo Picciotti, Giovanni Bubici

“…Photosynthesis and protein biosynthesis were the main down-regulated biological processes, while enzyme families such as oxidoreductases and transferases, genes related to the response to biotic stimuli, solute transport, and vesicle trafficking were overall up-regulated. …”
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Insulin-Like Growth Factor-1 and Selected Insulin-Like Growth Factor Binding Protein Concentrations during an Ultramarathon Sled Dog Race by Matthew W. Brunke, Christopher W. Frye, Corri B. Levine, Cristina Hansen, Joseph J. Wakshlag

“…IGF-1, IGFBP-1, and IGFBP-3 were assessed using radioimmunoassay or enzyme linked immune-absorbance assays. Mean prerace concentrations were significantly higher than midrace and end-race concentrations at 215.93 ± 80.51 ng/mL, 54.29 ± 25.45 ng/mL, and 55.53 ± 28.25 ng/mL, respectively (P<0.001). …”
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