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  1. 3081

    Antioxidant Potential of Adiponectin and Full PPAR-γ Agonist in Correcting Streptozotocin-Induced Vascular Abnormality in Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Edward James Johns, Olorunfemi A. Eseyin, Ali Attiq

    Published 2021-01-01
    “…Diabetic SHRs pretreated with pioglitazone and adiponectin separately exerted improvements in antioxidant enzyme activities, abrogated arterial stiffness, and offset the increased production of reactive oxygen species and dyslipidemic effects of STZ, whereas the blood pressure values were significantly reduced in the irbesartan-treated groups (all P<0.05). …”
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  2. 3082

    Correlation between serum neurofilament light chain and short-term outcomes in patients with hypertensive intracerebral hemorrhage by Jun Zhou, Yulin Zhao, Lichuang Zhang, Yanrui Dong, Zehu Li, Yansong Wang, Xiangdong Wang

    Published 2025-02-01
    “…The serum values of light chain protein of the experimental group and control group were measured by enzyme-linked immunosorbent assay. The Glasgow Outcome Scale of enrolled patients at 30 days of onset was recorded, and the collected data were statistically analyzed. …”
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  3. 3083

    Salivary stimulatory and anti-inflammatory effects of aqueous Lilium brownii var. viridulum Baker extract for Sjögren’s syndrome: in vitro and in vivo studies by Na-Yeon Ha, Haein Jeong, Mun Seog Chang, Jinsung Kim

    Published 2025-01-01
    “…AQP-5 and M3 muscarinic acetylcholine receptor (M3R) expression and inflammatory mediator levels were determined using western blotting and enzyme-linked immunosorbent assay. Histopathological examination of salivary glands was also performed. …”
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  4. 3084

    A Case–Control Study of the Association of Novel Androgens (11-KT and DHT), Classical Androgens (Testosterone and DHEAS), Hormones (LH, FSH, 17-OHP, Insulin, and SHBG), Insulin Res... by Nirmal Kumar, Neera Sharma, Smita Roy, Indu Chawla, Lokesh Kumar Sharma

    Published 2025-01-01
    “…The estimation of testosterone, DHEAS, 11-KT, and DHT was performed by the enzyme-linked immunoassay (ELISA) method. The assessment of biochemical and hormonal parameters was compared and correlated with 11-KT and DHT. …”
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  5. 3085

    Egg quality evaluation of japanese quail (Coturnix coturnix japonica) supplemented with powdered leaves of jute mallow (Corchorus olitorius) and siam weed (Chromolaena odorata) by Gemma M Guigue, Alejandro Jr B Dianon, Decem Mary Joice D Tolero

    Published 2025-01-01
    “…Additionally, the supplementation stimulates the digestive system, enhancing digestive enzyme production and feed utilization efficiency by improving liver function, as supported by [7]. …”
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  6. 3086

    PENGARUH PEMBERIAN ISOLAT KATEKIN GAMBIR (Uncaria gambir Roxb) TERHADAP KADAR HORMON TESTOSTERON DAN JUMLAH SPERMATOZOA TIKUS Rattus Norvegicus JANTAN HIPERGLIKEMIA by Ririn Marta Sari, Rauza Sukma Rita, Eliza Anas

    Published 2018-10-01
    “…Metode Penelitian ini merupakan penelitian experimental, Pemberian Isolat Katekin Gambir, selanjutnya dilakukan pengambilan darah pada vena retro orbita tikus yang digunakan untuk pemeriksaan kadar hormon testosteron dalam serum, kadar testosteron  di analisis dengan tekhnik Enzyme-Linked Immunosorbent Assay (ELISA) dan Vas Deferrens tikus untuk pengambilan spermatozoa menghitung jumlah spermatozoa dengan analisa sperma. …”
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  7. 3087

    Rat Hippocampal Neural Stem Cell Modulation Using PDGF, VEGF, PDGF/VEGF, and BDNF by Neus Gomila Pelegri, Catherine A. Gorrie, Jerran Santos

    Published 2019-01-01
    “…Cell growth and differentiation were assessed using immunohistochemistry and glutaminase enzyme assay. Cells were cultured for 14 days and treated with different growth factors at two different concentrations 20 ng/mL and 100 ng/mL. …”
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  8. 3088

    Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

    Published 2025-02-01
    “…We then focus on SARS-CoV-2 infection and show how the binding of the viral pathogen to the angiotensin-converting enzyme 2 receptor, as well as to NRP-1, leads to elevated levels of VEGF-A and consequences such as coagulation, vascular dysfunction, and inflammation. …”
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  9. 3089

    Combinatorial protective effect of Cinnamomum verum and Stingless Bee Honey against oxidative stress in isoproterenol-induced cardiotoxicity in Wistar rats by Arul Mozhi Padmanabhan, Victor Arokia Doss

    Published 2025-01-01
    “…Biochemical assays were conducted to measure antioxidant enzyme activities (Superoxide Dismutase, Catalase, Glutathione Peroxidase), non-enzymatic antioxidants (Vitamin C, Vitamin E, Reduced Glutathione), inflammatory markers, and oxidative stress levels. …”
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  10. 3090

    Hydroxychloroquine and Fabry Disease: Three Case Reports Examining an Unexpected Pathologic Link and a Review of the Literature by Rouhin Sen, Kathleen Borghoff, Kirk W. Foster, Stanley J. Radio, Alan Erickson, Michelene Hearth-Holmes

    Published 2022-01-01
    “…Lastly, we report the very interesting similarity in the intracellular action of hydroxychloroquine to the pathology of Fabry disease (and its associated lysosomal enzyme, α-galactosidase A). Case Presentation. We will examine the case presentations of three female Caucasian patients: a 22-year-old with lupus nephritis class V, a 72-year-old with long-standing systemic lupus erythematosus, and a 74-year-old with undifferentiated connective tissue disease. …”
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  11. 3091

    Challenges in Medicine: The Odyssey of a Patient with Isolated IgG4-Related Eosinophilic Angiocentric Fibrosis Presenting as a Locally Destructive Sinonasal Mass by Snigdha Nutalapati, Richard O’Neal, William O’Connor, Brett T. Comer, Gerhard C. Hildebrandt

    Published 2021-01-01
    “…Our case interestingly also had T-cell clonality and isolated isocitrate dehydrogenase 2 enzyme mutation on next-generation sequencing, suggesting a possible role of novel molecular-targeted therapies in this rare disease. …”
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  12. 3092

    A Comparative Study on Growth Performance, Body Composition, and Liver Tissue Metabolism Rearing on Soybean Lecithin-Enriched Artemia Nauplii and Microdiet in Rock Bream (Oplegnath... by Pian Zhang, Peng Tan, Lei Zhang, Wenliang Zhu, Ruiyi Chen, Ligai Wang, Dongdong Xu

    Published 2023-01-01
    “…Larvae fed a MD showed decreased lipolysis-related lipase activity as well as decreased amino acid catabolism-related alanine aminotransferase and aspartate aminotransferase enzyme activities in liver tissue. RNA sequencing revealed that feeding with the MD primarily increased the expression of lipogenesis-related genes and protein translation-related gene expression in the liver tissue. …”
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  13. 3093

    Triptolide Inhibits Th17 Response by Upregulating microRNA-204-5p and Suppressing STAT3 Phosphorylation in Psoriasis by Qi He, Xingyue Wu, Quan Shi

    Published 2022-01-01
    “…The combination between microRNA-204-5p (miR-204-5p) and signal transduction and transcription activator-3 (STAT3) was confirmed by luciferase reporter assay. Enzyme-linked immunosorbent assay was conducted to examine interleukin (IL)-17 and interferon-γ (IFN-γ) levels using corresponding kits. …”
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  14. 3094

    The Therapeutic Effect of Adipose-Derived Mesenchymal Stem Cells for Radiation-Induced Bladder Injury by Xuefeng Qiu, Shiwei Zhang, Xiaozhi Zhao, Kai Fu, Hongqian Guo

    Published 2016-01-01
    “…Twelve weeks after radiation, urinary bladder tissue was collected for histological assessment and enzyme-linked immunosorbent assay (ELISA) after metabolic cage investigation. …”
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  15. 3095

    A systematic in vitro study of the effect of normoglycaemic and hyperglycaemic conditions on the biochemical and cellular interactions of clinically-available wound dressings with... by Shirin Saberianpour, Gianluca Melotto, Rachel Forss, Lucy Redhead, Susan Sandeman, Nadia Terrazzini, Dipak Sarker, Matteo Santin

    Published 2025-01-01
    “…Non-woven absorbent layers based on carboxymethyl cellulose mainly stimulating the iNOS, an enzyme producing free radicals; in the case of Kerracel this was combined with a swelling of fibres preventing the penetration of cells. …”
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  16. 3096

    Recent Advances and Perspectives on the Use of Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Chronic Kidney Disease: A Review by Kisho Miyasako, Yujiro Maeoka, Takao Masaki

    Published 2024-12-01
    “…The current therapies, including angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and sodium–glucose co-transporter 2 inhibitors, are administered to control hypertension, slow the progression of CKD, and reduce cardiovascular risk. …”
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  17. 3097

    The Effect of Varied Time Interval and Micro-Current (Direct) on the Level of Biomarker (IL-6) and Rate of Tooth Movement: An Animal Study by Parnita Dwivedi, Ashish Agrawal, Subash Chandra Gupta, Tehmin Chou

    Published 2023-10-01
    “…Interleukin-6 (IL-6) concentration was accessed using enzyme-linked immunosorbent assay (ELISA). The data were subjected to one-way ANOVA and Tukey’s post hoc test. …”
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  18. 3098

    Alterations in Serum Adropin, Adiponectin, and Proinflammatory Cytokine Levels in OSAS by Hakan Celikhisar, Gulay Dasdemir Ilkhan

    Published 2020-01-01
    “…The serum adropin and adiponectin levels of all cases were analyzed via the enzyme-linked immunosorbent assay method. Serum interleukin-1 (IL-1) beta and tumor necrotizing factor-alpha (TNF-alpha) levels were determined using Luminex cytokine multiplex analyses. …”
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  19. 3099

    SHMT2 Overexpression Predicts Poor Prognosis in Intrahepatic Cholangiocarcinoma by Shanglei Ning, Siquan Ma, Abdul Qahar Saleh, Lingyu Guo, Zixiao Zhao, Yuxin Chen

    Published 2018-01-01
    “…Serine hydroxymethyltransferase 2 (SHMT2) functions as a key enzyme in serine/glycine biosynthesis and one-carbon metabolism. …”
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  20. 3100

    Flavocytochrome b2-Based Enzymatic Method of L-Lactate Assay in Food Products by Oleh Smutok, Maria Karkovska, Halyna Smutok, Mykhailo Gonchar

    Published 2013-01-01
    “…The main advantages of the proposed method when compared to the LDH-based routine approaches are a higher sensitivity (2.0 μM of L-lactate), simple procedure of analysis, usage of inexpensive, nontoxic reagents, and small amount of the enzyme. Enzymatic oxidation of L-lactate catalyzed by flavocytochrome b2 and coupled with formazan production from nitrotetrazolium blue was shown to be used for L-lactate assay in food samples. …”
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