JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells by Ling Yan, Shengnan Liu, Chen Wang, Fei Wang, Yingli Song, Nan Yan, Shuhua Xi, Ziyou Liu, Guifan Sun

“…In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extracellular superoxide in microglia. …”
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Seroprevalence and Risk Factors Associated with Hepatitis E Virus Infection in Three Species of Pet Birds in Northwest China by Wei Cong, Qing-Feng Meng, Xiao-Feng Shan, Wu-Wen Sun, Si-Yuan Qin, Xiao-Xuan Zhang, Si-Yang Huang, Ai-Dong Qian

“…A total of 59 (8.31%) pet birds were tested positive for HEV antibodies by the commercially available enzyme immunoassay kits. Of these, the seroprevalence was diverse in different species pet birds; the most frequent level was 10.83% (39/360) in Eurasian siskin, followed by 6.57% (19/289) in Oriental skylark, and 2.29% (1/36) in black-tailed grosbeak. …”
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Exploring Echinacea angustifolia for anti-viral compounds against Zika virus RNA-dependent RNA polymerase: a computational study by Mai M. El-Daly, Leena H. Bajrai, Thamir A. Alandijany, Isra M. Alsaady, Hattan S. Gattan, Meshari M. Alhamdan, Vivek Dhar Dwivedi, Esam I. Azhar

“…This study explores the potential of compounds from Echinacea angustifolia (E. angustifolia) to inhibit the activity of ZIKV’s RNA-dependent RNA polymerase (RDRP), a key enzyme in the viral replication process and an ideal candidate for antiviral therapy. …”
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Conformational and Functional Properties of Soybean Proteins Produced by Extrusion-Hydrolysis Approach by Wenjun Ma, Baokun Qi, Rokayya Sami, Lianzhou Jiang, Yang Li, Hui Wang

“…The hydrolysis degrees, molecular weight profiles, solubilities, surface hydrophobicities, sulphydryl contents, disulfide bound, water holding capacity, emulsion, and foam properties of the protein isolated from the enzyme-hydrolyzed extruded soybeans were analyzed. …”
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Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole-Triazoles as Potential Lanosterol 14α-Demethylase Inhibitors by Nafiz Öncü Can, Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Serkan Levent, Büşra Korkut, Yusuf Özkay, Zafer Asım Kaplancıklı, Ali Savaş Koparal

“…The molecular docking studies were performed to investigate the interaction modes between the compounds and active site of lanosterol 14-α-demethylase (CYP51), which is as a target enzyme for anticandidal azoles. Theoretical ADME predictions were also calculated for final compounds.…”
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Blastomyces dermatitidis Yeast Lysate Antigen Combinations: Antibody Detection in Dogs with Blastomycosis by Alex R. Boyd, Jamie L. VanDyke, Gene M. Scalarone

“…Based on results obtained from a preliminary comparative study, five combinations of these isolates and one individual isolate were tested against 92 serum specimens from dogs with culture-proven or histologically-confirmed blastomycosis, using the indirect enzyme-linked immunosorbent assay (ELISA). Mean absorbance values obtained from the sera ranged from 0.905 with the individual T-58 antigen to 1.760 using an antigen combination (T-58 + T-66 + WI-R). …”
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The m6A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells by Qian Gao, Jin Zheng, Zegui Ni, Pengli Sun, Congcong Yang, Maosheng Cheng, Mingqing Wu, Xiuhong Zhang, Lin Yuan, Yingyin Zhang, Yang Li

“…Here, we show that global RNA m6A abundance and the expression of m6A-forming enzyme METTL3 are higher in BCSCs than those in non-CSCs of bladder cancer (BCa) cells. …”
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A novel source of phytochemical and bioactive peptide from fermented mushroom trimming waste extract by Bifidobacterium longum by Napassorn Peasura, Pornrat Sinchaipanit, Kanokwan Yodin

“…The chemical changes and phytochemicals were investigated, as well as antioxidant activity during fermentation, and biological activities such as angiotensin-converting enzyme (ACE) inhibition were investigated. The results found that the growth of B. longum was increased during 0–24 h, while viability declined after 24 h. …”
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Curcumin mimics of potential chemoprevention with NQO1 induction properties by Dalia R. Aboshouk, Ahmed R. Hamed, Siva S. Panda, Mohamed S. Bekheit, M. Adel Youssef, Adel S. Girgis

“…NAD(P)H quinone oxidoreductase 1 (NQO1) is a xenobiotic metabolizing cytosolic enzyme/protein with important functional properties towards oxidation stress, supporting its ability in detoxification/chemoprotective role. …”
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A Single Lung Transplant in a Patient with Fabry Disease: Causality or Far-Fetched? A Case Report by Martina Gaggl, Renate Kain, Peter Jaksch, Dominik Haider, Gerald Mundigler, Till Voigtländer, Raute Sunder-Plassmann, Paulus Rommer, Walter Klepetko, Gere Sunder-Plassmann

“…Overall, the patient might have benefited from specific enzyme replacement therapy, especially in view of the chronic kidney disease.…”
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Predictive and Prognostic Value of sPRR in Patients with Primary Epithelial Ovarian Cancer by Katrin Kreienbring, Annika Franz, Rolf Richter, Duska Dragun, Harald Heidecke, Ralf Dechend, Dominik N. Muller, Jalid Sehouli, Elena I. Braicu

“…In this study 197 patients with primary EOC in our institution from 2000 to 2011 were included. sPRR was determined by enzyme-linked immunosorbent assay (ELISA) in preoperative taken blood sera. …”
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Indoxyl Sulfate Induces Mesangial Cell Proliferation via the Induction of COX-2 by Shuzhen Li, Sijie Cheng, Zhenzhen Sun, Harr-keshauve Mungun, Wei Gong, Jing Yu, Weiwei Xia, Yue Zhang, Songming Huang, Aihua Zhang, Zhanjun Jia

“…Next, we found an inducible inflammation-related enzyme COX-2 was remarkably enhanced by IS, and the inhibition of COX-2 by NS398 significantly blocked IS-induced MC proliferation in line with a blockade of PGE2 production. …”
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Site Saturation Mutagenesis Applications on Candida methylica Formate Dehydrogenase by Gülşah P. Özgün, Emel B. Ordu, H. Esra Tütüncü, Emrah Yelboğa, Richard B. Sessions, Nevin Gül Karagüler

“…In NADH regeneration, Candida methylica formate dehydrogenase (cmFDH) is a highly significant enzyme in pharmaceutical industry. In this work, site saturation mutagenesis (SSM) which is a combination of both rational design and directed evolution approaches is applied to alter the coenzyme specificity of NAD+-dependent cmFDH from NAD+ to NADP+ and increase its thermostability. …”
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Symmetric Dimethylarginine Is Not Associated with Cumulative Inflammatory Load or Classical Cardiovascular Risk Factors in Rheumatoid Arthritis: A 6-Year Follow-Up Study by Theodoros Dimitroulas, James Hodson, Aamer Sandoo, Jacqueline P. Smith, Karen M. Douglas, George D. Kitas

“…At follow-up (2012) SDMA levels were measured by enzyme-linked immunosorbent assay. Mean SDMA levels in RA population were 0.40 (0.40–0.53) μmol/L. …”
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Effect of MgSO4 as a complement to NPK fertilizer on shallot growth by Syamsiyah Jauhari, Herdiansyah Ganjar, Komariah, Gumilang Bardhian Cahyo Aji, Wijaya Lidya Zaela, Siswantoro Hendricus William

“…Magnesium Sulphate (MgSO4) role in photosynthesis, enzyme activation, and synergism with other nutrients plays big part in increasing plant growth and harvest. …”
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Enzymatic β-Mannosylation of Phenylethanoid Alcohols by Lucia Černáková, Peter Haluz, Vladimír Mastihuba, Zuzana Košťálová, Elena Karnišová Potocká, Mária Mastihubová

“…We found that Novozym 188, an industrial β-glucosidase, also contains β-mannosidase and used this enzyme in the preparation of tyrosol β-D-mannopyranoside and hydroxytyrosol β-D-mannopyranoside in 12 and 16% chemical yields, respectively, by transglycosylation from β-D-mannopyranosyl-(1→4)-D-mannose. …”
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Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…Alkaline phosphatase (ALP) is a ubiquitously expressed dephosphorylating enzyme and its level in blood is widely used as a diagnosis marker of liver damage or bone disorders in human patients. …”
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Advancing Slope Stability and Hydrological Solutions Through Biocementation: A Bibliometric Review by Armstrong Ighodalo Omoregie, Tariq Ouahbi, Fock-Kui Kan, Qurratu Aini Sirat, Hafsat Omolara Raheem, Adharsh Rajasekar

“…The analysis reveals that China, the United States, and Japan are leading contributors to this field, with significant advancements in microbial-induced (MICP) and enzyme-induced calcium carbonate precipitation (EICP) techniques. …”
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Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin by Svetlana I. Galkina, Natalia V. Fedorova, Marina V. Serebryakova, Evgenii A. Arifulin, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’ina

“…Simultaneous detection of neutrophil secretory products by mass spectrometry showed that all tested stimuli caused the secretion of MMP-9, a key enzyme in the neutrophil migration. Cytochalasin D impaired the MMP-9 secretion but initiated the release of cathepsin G and other granular bactericides, proinflammatory agents. …”
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Antihypertensive effect of sinapine extracted from rapeseed meal in 2K1C hypertensive rats by Gaoyuan Yang, Lin Zhu, Yu Wang, Yang Yu, Xiaoguang Liu, Jingbo Xia, Yunjie Yang, Huiguo Wang, Baomin Feng

“…The renin angiotensin aldosterone system (RAAS), including the levels of renin, angiotensin I (Ang I), angiotensin II (Ang II), aldosterone (ALD), angiotensin-converting enzyme (ACE) and other molecules related to blood pressure, such as NO, prostacyclin (PGI2), endothelin-1 (ET1), and thromboxane A2 (TXA2), were measured in rat blood. …”
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