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2701
Enhancing phosphorus availability and dynamics in acidic soils through Rice straw biochar application: a sustainable alternative to chemical fertilizers
Published 2025-02-01“…The results indicate that biochar significantly increased phosphorus availability, enhanced soil enzyme activity, and boosted microbial phosphorus content, especially in the phosphorus-deficient red soil. …”
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2702
A Novel ZnO-Methylene Blue Nanocomposite Matrix for Biosensing Application
Published 2011-01-01“…Glucose oxidase (GOx) was chosen as the model enzyme and effectively immobilized on the surface of hybrid ZnO-MB nanocomposite matrix. …”
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2703
Validation of Simultaneous Quantitative Method of HIV Protease Inhibitors Atazanavir, Darunavir and Ritonavir in Human Plasma by UPLC-MS/MS
Published 2014-01-01“…HIV protease inhibitors are used in the treatment of patients suffering from AIDS and they act at the final stage of viral replication by interfering with the HIV protease enzyme. The paper describes a selective, sensitive, and robust method for simultaneous determination of three protease inhibitors atazanavir, darunavir and ritonavir in human plasma by ultra performance liquid chromatography-tandem mass spectrometry. …”
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2704
Comparison of Vitamin-D binding protein levels in gingival crevicular fluid of pre- and postmenopausal women with and without chronic periodontitis: A clinico-biochemical study
Published 2023-07-01“…GCF DBP levels were evaluated using an enzyme-linked immunosorbent assay kit. Results: There was a significant correlation between menopausal status and periodontal status in relation to GCF DBP levels (P = 0.000). …”
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2705
Mechanism of modified mRNA structure in COVID-19 vaccines for inducing neutralizing antibodies
Published 2024-10-01“…Vaccines like BNT162b2 and mRNA-1273 target the receptor-binding domain (RBD) of the spike (S) protein, prompting B cells to produce neutralizing antibodies that block the RBD from binding to the Angiotensin-Converting Enzyme 2 (ACE2) receptor, preventing infection. These vaccines also stimulate adaptive immune responses by activating CD4+ and CD8+ T cells, with mRNA functioning as an endogenous antigen. …”
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2706
ACE Inhibitor-Induced Angioedema of the Intestine: Case Report, Incidence, Pathophysiology, Diagnosis and Management
Published 2001-01-01“…Angiotensin-converting enzyme (ACE) inhibitor-induced angioedema of the intestine (AIAI) occurs in a minority of patients taking an ACE inhibitor. …”
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2707
An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment
Published 2021-01-01“…Digoxin treatment significantly reduced the liver enzyme ALT, plasma TNF-α, TGF-β, PTX3, and MDA levels and decreased histological changes in the liver tissue with MTX-induced hepatotoxicity in the rat model. …”
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2708
Selectivity of Inhibition of N-Succinyl-l,l-Diaminopimelic Acid Desuccinylase in Bacteria: The product of dapE-gene Is Not the Target of l-Captopril Antimicrobial Activity
Published 2011-01-01“…Recently, l-captopril has been suggested as a lead compound for inhibition of DapE, although its selectivity for this enzyme target in bacteria remains unclear (Gillner et al. (2009)). …”
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2709
Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis
Published 2023-08-01“…This is much supported by the role of the endoplasmic reticulum aminopeptidase 1 (ERAP 1) in AS, an enzyme that is responsible for the intracellular trimming of peptides, since polymorphisms of this gene are only associated with HLA-B27+ disease. …”
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2710
Low-Dose Fluvastatin Prevents the Functional Alterations of Endothelium Induced by Short-Term Cholesterol Feeding in Rabbit Carotid Artery
Published 2012-01-01“…In this study, we investigated the effects of low-dose fluvastatin on antioxidant enzyme activities (superoxide dismutase, SOD; catalase), total nitrite/nitrate levels, and vascular reactivity in 2% cholesterol-fed rabbits. …”
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2711
The Role of Sulfatides in Liver Health and Disease
Published 2025-01-01“…We have recently demonstrated how loss of function of GAL3ST1, a limiting enzyme involved in sulfatide synthesis, reduces tumorigenic capacity in cholangiocarcinoma (CCA) cells. …”
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2712
Matched serum- and urine-derived biomarkers of interstitial cystitis/bladder pain syndrome.
Published 2024-01-01“…A total of 33 different biomarkers were measured, including cytokines and chemokines, proteins involved in extracellular matrix remodeling, adhesion molecules, growth factors, and markers of oxidative stress using enzyme linked immunoassays and multiplex technology. …”
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2713
Association of PIK3CA somatic mutations with clinicopathological parameters in breast cancer
Published 2024-12-01“…The enzyme phosphatidylinositide-3-kinase (PI3K) regulates cellular proliferation and apoptosis. …”
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2714
Investigation into the sero-molecular prevalence of Brucella melitensis in small ruminants in districts Mohmand and Charsadda Khyber Pakhtunkhwa Pakistan.
Published 2025-01-01“…A total of 400 blood samples were collected from sheep and goats (n = 200 from each species) and analyzed by Rose Bengal precipitation test (RBPT), the indirect enzyme-linked immunosorbent assay (i-ELISA) and polymerase chain reaction (PCR). …”
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2715
Comparison of different methods for identification of meat species in meat products
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2716
Optimisation and In Vivo Evaluation of Pectin Based Drug Delivery System Containing Curcumin for Colon
Published 2014-01-01“…., percent drug release after 4 hours (Y240) and difference in percent drug release between 4th and 6th hour (Ydiff) in presence of pectinase enzyme. The results revealed that higher coat weight (600 mg) and higher level of pectin ratio (70% w/w) protected the curcumin tablet till ascending colon. …”
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2717
Exploration of Potent Human α-Glucosidase Inhibitors Using In Silico Approaches: Molecular Docking, DFT, Molecular Dynamics Simulations, and MMPBSA
Published 2024-01-01“…Inhibiting α-glucosidase, a key enzyme in carbohydrate hydrolysis, can potentially control diabetes mellitus. …”
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2718
Valorization of Waste Cooking Oil into Biodiesel via Bacillus stratosphericus Lipase Amine-Functionalized Mesoporous SBA-15 Nanobiocatalyst
Published 2022-01-01“…High-resolution X-ray diffractometer, Fourier transform infrared spectroscopy, N2 adsorption-desorption, field-emission scanning electron, and high-resolution transmission electron microscopic analyses proved the successful SBA-15 functionalization and enzyme immobilization. Response surface methodology based on a 1/2 fraction-three-levels face center composite design was applied to optimize the biodiesel transesterification process. …”
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2719
Potentials of Curcumin as an Antidepressant
Published 2009-01-01“…Although the mechanism of the antidepressant effect of curcumin is not fully understood, it is hypothesized to act through inhibiting the monoamine oxidase enzyme and modulating the release of serotonin and dopamine. …”
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2720
A Single-Reactor System for Simultaneous Pretreatment and Fermentation of POME for Bioethanol Production
Published 2024-01-01“…The aim was to establish a process for bioethanol synthesis using hydrolyzed palm oil mill effluent (POME) and a locally sourced cellulase enzyme. The pretreatment and enzymatic hydrolysis methods were successfully optimized, resulting in a maximum yield of reducing sugars of 26.6 g/L (53.14%). …”
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