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  1. 2661

    Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Dise... by Kang Tang, Chunmei Zhang, Yusi Zhang, Yun Zhang, Ran Zhuang, Boquan Jin, Ying Ma

    Published 2017-01-01
    “…To investigate the possible effects of APN in the pathogenesis of HFRS, total and high molecular weight (HMW) APN levels in the plasma of patients with HFRS were quantified using enzyme-linked immunosorbent assay (ELISA). Compared with those in healthy controls, the plasma total and HMW APN levels in patients were elevated to different degrees from the fever onset and remained high at the convalescent phase. …”
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  2. 2662

    Interaction mechanism of egg white- derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptor by Zhipeng Yu, Hui Guo, David Shiuan, Chensi Xia, Wenzhu Zhao, Long Ding, Fuping Zheng, Jingbo Liu

    Published 2020-03-01
    “…The egg white-derived hexapeptide TNGIIR inhibits angiotensin-converting enzyme (ACE) activity in vitro. In this work, molecular docking revealed that TNGIIR established hydrogen bonds with the S1 (Ala 354), S2 (Gln 281, His 513, Tyr 520 and Lys 511) and S1′ (Glu 162) pockets of ACE. …”
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  3. 2663

    Gold nanorod-based engineered nanogels for cascade-amplifying photothermo-enzymatic synergistic therapy by Ling Ding, Xiaoshan Wang, Qing Wu, Xia Wang, Qigang Wang

    Published 2024-12-01
    “…This ultimately promoted the efficient enzyme-catalyzed reaction of loaded CPO combined with the rich endogenous H2O2 in tumor cells to significantly elevate intracellular ROS levels above the threshold for improved therapeutic outcomes. …”
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  4. 2664

    Comparison of VIDAS and Radioimmunoassay Methods for Measurement of Cortisol Concentration in Bovine Serum by Daniela Proverbio, Roberta Perego, Eva Spada, Giada Bagnagatti de Giorgi, Angelo Belloli, Davide Pravettoni

    Published 2013-01-01
    “…The VIDAS cortisol test is an enzyme-linked fluorescent assay designed for the MiniVidas system. …”
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  5. 2665

    Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats by Yogesha Mohan, Grace Nirmala Jesuthankaraj, Narendhirakannan Ramasamy Thangavelu

    Published 2013-01-01
    “…Various parameters were studied and the treatment group with the extract showed a significant increase in the liver glycogen and a significant decrease in fasting blood glucose, glycosylated hemoglobin levels, and serum marker enzyme levels. The total cholesterol and serum triglycerides levels, low density lipoprotein, and very low density lipoprotein were also significantly reduced and the high density lipoprotein level was significantly increased upon treatment with the Triticum aestivum ethanol extract. …”
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  6. 2666

    Self‐Driving Lab for Solid‐Phase Extraction Process Optimization and Application to Nucleic Acid Purification by Sebastian Putz, Jonathan Döttling, Tim Ballweg, Andre Tschöpe, Vitaly Biniyaminov, Matthias Franzreb

    Published 2025-01-01
    “…Sorptive bioprocesses are the basis for numerous biotechnological applications such as enzyme immobilization, biosensors, controlled drug delivery, water treatment, and molecular purification. …”
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    Article
  7. 2667

    Aspirin Modulates Innate Inflammatory Response and Inhibits the Entry of Trypanosoma cruzi in Mouse Peritoneal Macrophages by Aparecida Donizette Malvezi, Rosiane Valeriano da Silva, Carolina Panis, Lucy Megumi Yamauchi, Maria Isabel Lovo-Martins, Nagela Ghabdan Zanluqui, Vera Lúcia Hideko Tatakihara, Luiz Vicente Rizzo, Waldiceu A. Verri, Marli Cardoso Martins-Pinge, Sueli Fumie Yamada-Ogatta, Phileno Pinge-Filho

    Published 2014-01-01
    “…Here, we present evidence suggesting the involvement of the host’s cyclooxygenase (COX) enzyme during T. cruzi invasion. Pharmacological antagonist for COX-1, aspirin (ASA), caused marked inhibition of T. cruzi infection when peritoneal macrophages were pretreated with ASA for 30 min at 37°C before inoculation. …”
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  8. 2668

    The Effects of Microplastic Pollution on Marine Organisms and its Impact on Human Health: A Review by Aran Akbari, Jalil Jaafari

    Published 2025-01-01
    “…Exposure of marine organisms to MPs can lead to weight loss, reduced growth, reduced reproduction, changes in feeding behavior, changes in enzyme activity, initiation of stress response, and inflammatory response. …”
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  9. 2669

    Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B1-Induced Experimental Hepatocellular Carcinoma by Vijaya Ravinayagam, Ravindran Jaganathan, Sachdanandam Panchanadham, Shanthi Palanivelu

    Published 2012-01-01
    “…AFB1-administered HCC-bearing rats (Group II) showed increased levels of lipid peroxides (LPOs), thiobarbituric acid substances (TBARs), and protein carbonyls (PCOs) and decreased levels of enzymic and nonenzymic antioxidants when compared to control animals (Group I). …”
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  10. 2670

    Angioedema due to enalapril. A case report by Belkis Barrios Romero, Ana María Ramos Cedeño, Yeny Dueñas Pérez, Mirtha Amarilis Hernández López

    Published 2023-07-01
    “…Angiotensin converting enzyme inhibitors are used by more than 40 million people worldwide for the treatment of cardiovascular diseases. …”
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  11. 2671

    The Impact of Daily Light Integral from Artificial Lighting on Tomato Seedling Cultivation in Plant Factory by Minggui Zhang, Jiawei Cui, Jun Ju, Youzhi Hu, Xiaojuan Liu, Rui He, Jiali Song, Yanwu Huang, Houcheng Liu

    Published 2024-12-01
    “…The optimal DLI enhanced seedling growth, biomass, root vitality, antioxidant enzyme activity, and photosynthetic pigment synthesis. …”
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  12. 2672

    Etanercept Attenuates Traumatic Brain Injury in Rats by Reducing Brain TNF-α Contents and by Stimulating Newly Formed Neurogenesis by Chong-Un Cheong, Ching-Ping Chang, Chien-Ming Chao, Bor-Chih Cheng, Chung-Zhing Yang, Chung-Ching Chio

    Published 2013-01-01
    “…The numbers of the colocalizations of 5-bromodeoxyuridine and doublecortin specific markers in the contused brain injury that occurred during TBI were counted by immunofluorescence staining. Enzyme immunoassay for quantitative determination of TNF-α or etanercept in brain tissues is also performed. …”
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  13. 2673

    Optimizing Varicella Vaccination Strategy: A Study on Age and Dose Impacts on Antibody Levels by Qing He, Yang Xu, Yilan Li, Pinting Zhu, Lei Luo

    Published 2024-12-01
    “…We measured varicella antibody concentrations using an enzyme-linked immunosorbent assay. A total of 3300 people were enrolled in the study. …”
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  14. 2674

    Enzymatic Hydrolysis and Fermentation of Banana Pseudostem Hydrolysate to Produce Bioethanol by Lesetja Moraba Legodi, Daniel Coenrad LaGrange, Elbert Lukas Jansen van Rensburg, Ignatious Ncube

    Published 2021-01-01
    “…Saccharification of the pretreated BPS with 10 FPU/g dry solids (29.3 mg protein/g d.s) crude enzyme from Trichoderma harzianum LMLBP07 13-5 at 50°C and a substrate loading of 10 to 15% released 3.8 to 21.8 g/L and from T. longibrachiatum LMLSAUL 14-1 released 5.4 to 43.5 g/L glucose to the biomass. …”
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  15. 2675

    A Liquid Chromatography-Tandem Mass Spectrometry Method for Evaluation of Two Brands of Enalapril 20 mg Tablets in Healthy Human Volunteers by Wael Abu Dayyih, Mohammed Hamad, Ahmad Abu Awwad, Eyad Mallah, Zainab Zakarya, Alice Abu Dayyih, Tawfiq Arafat

    Published 2017-01-01
    “…Enalapril is an angiotensin-converting enzyme inhibitor used for treatment of hypertension and chronic heart disease. …”
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  16. 2676

    Combating antibiotic resistance: mechanisms, challenges, and innovative approaches in antibacterial drug development by Aiswarya M. Rajesh, Shraddha Subhash Pawar, Kruthi Doriya, Rambabu Dandela

    Published 2025-01-01
    “…Bacteria have evolved complex resistance strategies, such as enzyme production to neutralize drugs, modifying drug targets, and using efflux pumps to remove antibiotics, significantly reducing drug efficacy. …”
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  17. 2677

    Mononuclear Aluminum–Fluoride Ions, AlF<i><sub>x</sub></i><sup>(+/−)</sup>—Study of Plausible Frameworks of Complexes with Biomolecules and Their In Vitro Toxicity by Anja Pavlovič, Larisa Janžič, Lucija Sršen, Andreja Nataša Kopitar, Kathleen F. Edwards, Joel F. Liebman, Maja Ponikvar-Svet

    Published 2025-01-01
    “…Our review of salts of ionic AlF<i><sub>x</sub></i> species, which plausibly form the framework of complexes with biomolecules, revealed that the octahedral configuration of aluminum in the active site of the enzyme is preferred over the trigonal-bipyramidal structure. …”
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  18. 2678

    Gram-Negative Bacterial Lipopolysaccharide Stimulates Activin A Secretion from Human Amniotic Epithelial Cells by Yumiko Abe, Risa Marukawa, Nami Tsuru, Maki Sato, Hiroko Matsuda, Hisanobu Sadakata, Takashi Kameda, Takashi Minegishi

    Published 2013-01-01
    “…The activin A concentrations in the culture media were measured by enzyme-linked immunosorbent assay, and cell proliferation was assessed by 5-bromo-2′-deoxyuridine incorporation. …”
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  19. 2679

    Polymorphonuclear Leukocytes or Hydrogen Peroxide Enhance Biofilm Development of Mucoid Pseudomonas aeruginosa by Qi Tan, Qing Ai, Qi Xu, Fang Li, Jialin Yu

    Published 2018-01-01
    “…Additionally, PMNs increased the activity of GDP-mannose dehydrogenase, which is the key enzyme in alginate biosynthesis. Our results demonstrate that PMNs or H2O2 can enhance mucoid P. aeruginosa biofilms.…”
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  20. 2680

    Biodegradability of Cellulose Fibers, Films, and Particles: A Review by Martin A. Hubbe, Jesse S. Daystar, Richard A. Venditti, Joel J. Pawlak, Marielis C. Zambrano, Morton Barlaz, Mary Ankeny, Steven Pires

    Published 2025-02-01
    “…Although cellulose is subject to well-known enzyme-promoted mechanisms of biodegradation, the evolution of plant materials has favored development of some resistance to decay, i.e. recalcitrance. …”
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