On the Toxicity of Therapeutically Used Nanoparticles: An Overview by A. El-Ansary, S. Al-Daihan

“…Effect of therapeutically used nanoparticles on cell membrane, mitochondrial function, prooxidant/antioxidant status, enzyme leakage, DNA, and other biochemical endpoints was elucidated. …”
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Effects of Macrofungal Polysaccharides Combined with Vemurafenib on Melanoma and Its Associated Mechanism by Wenya Wu, Zhigang Su, Shasha Fan

“…In this study, a melanoma mouse model was constructed, and a macrofungal polysaccharide (MFPS) extracted from Pleurotus ostreatus combined with Vemurafenib monoclonal antibody was used to study their effects against melanoma and its antitumor mechanism by using the lactate dehydrogenase release assay, enzyme-linked immunosorbent assay, and flow typing assay. …”
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Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin by Mohammad Samiei, Atefeh Abedi, Simin Sharifi, Solmaz Maleki Dizaj

“…Calcitriol alone increased the enzyme more than in combination with curcumin. These findings demonstrate that curcumin can induce early osteogenic differentiation of DPSCs like calcitriol as a potent stimulant of osteogenesis.…”
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The Binding Affinity of Small Molecules with Yam Tyrosinase (Catechol Oxidase): A Biophysical Study by Tabassum Mulla, Sushama Patil, Srinivas Sistla, Jyoti Jadhav

“…Yam tyrosinase has become an economically essential enzyme due to its ease of purification and abundant availability of yam tubers. …”
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FDA’s approval of resmetirom (Rezdiffra): a breakthrough in MASH management by Muhammad Mazhar Azam, Sameen Mukhtar, Muhammad Haris, Fatima Laique, Suhaina Amir, Mubashir Mohiuddin, Bibek Giri

“…This mechanism effectively reduces fibrosis markers, improves liver enzyme levels, and minimizes liver fat buildup. Clinical trials have shown that resmetirom has a favorable safety profile, with manageable side effects like diarrhea and nausea. …”
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Synthesis and Crystalline Structure of Zinc Complexes with Antihypertensive Drug Lisinopril by Márcia C. de Souza, Luan F. Diniz, Chris H. J. Franco, Renata Diniz

“…The structural investigation of Zn2+ complexes with the ligand lisinopril (LIS), an inhibitor of angiotensin-converting enzyme (ACE), was performed. The main objective is to compare if Zn-LIS coordination in vitro is similar to that observed in vivo. …”
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ASSESSMENT OF CYTOKINE LEVEL IN BLOOD SERUM IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION IN THE FIRST TRIMESTER OF PREGNANCY by Лариса Дмитриевна Андосова, Анна Алексеевна Дмитриева, Людмила Васильевна Боровкова, Светлана Олеговна Колобова, Ксения Андреевна Шахова, Юлия Рудольфовна Тихомирова, Александр Алексеевич Туличев, Людмила Александровна Чичкова

“…Cytokine levels were determined by enzyme-linked immunosorbent assay. Results. The results of the study revealed that women with chronic arterial hypertension had statistically significantly lower levels of IL-8 and MCP-1. …”
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Forced Air Precooling Enhanced Storage Quality by Activating the Antioxidant System of Mango Fruits by Jian Li, Yingli Fu, Jiaqi Yan, Huanlu Song, Weibo Jiang

“…Biochemical studies revealed that precooling treatment could eliminate reactive oxygen species (ROS) effects by enhancing related antioxidant enzyme activities, such as superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), glutathione reductase (GR), and polyphenoloxidase (PPO). …”
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A Case of Undetected Neuroborreliosis in a 75-Year-Old Chinese Male by Jenny Lamichhane, Rohail Haider, Michael Bekkerman, Sean Tilford, Shireen Hijaz, Bikash Bhattarai, Rajanish Bobde

“…Patients are identified based on their clinical symptoms and then diagnosed through enzyme-linked immunosorbent assay (ELISA), Western blot, and blood culture techniques. …”
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Increased NTPDase Activity in Lymphocytes during Experimental Sepsis by Claudia de Mello Bertoncheli, Carine Eloise Prestes Zimmermann, Jeandre Augusto dos Santos Jaques, Cláudio Alberto Martins Leal, Jader Betsch Ruchel, Bruna Cipolatto Rocha, Kelly de Vargas Pinheiro, Viviane do Carmo Gonçalves Souza, Daniel Roulim Stainki, Sônia Cristina Almeida Luz, Maria Rosa Chitolina Schetinger, Daniela Bitencourt Rosa Leal

“…We investigated in rats induced to sepsis the activity of ectonucleoside triphosphate diphosphohydrolase (NTPDase; CD39; E.C. 3.6.1.5), an enzyme involved in the modulation of immune responses. …”
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Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism by Michael L. Cunningham, Bradley J. Collins, Milton R. Hejtmancik, Ronald A. Herbert, Gregory S. Travlos, Molly K. Vallant, Matthew D. Stout

“…Increases in peroxisomal enzyme activities were greatest in rats, intermediate in mice, and least in hamsters. …”
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Rapid and simple determination of histamine-N-methyl transferase activity by high-performance liquid chromatography with UV detection by Hajime Inoue, Ken-Ichi Hisamatsu, Miki Yamauchi, Norio Kumagai

“…The new assay technique could detect methylhistamine as an enzyme activity product of histamine-N-methyltransferase in the brain and kidney of rats. …”
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Variation in Macro and Trace Elements in Progression of Type 2 Diabetes by Khalid Siddiqui, Nahla Bawazeer, Salini Scaria Joy

“…Trace elements participate in tissue and cellular and subcellular functions; these include immune regulation by humoral and cellular mechanisms, nerve conduction, muscle contractions, membrane potential regulations, and mitochondrial activity and enzyme reactions. The status of micronutrients such as iron and vanadium is higher in type 2 diabetes. …”
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Iron- Refractory Iron Deficiency Anemia: Review Article by Eman Ahmed Abd -Elmawgood, Mohammed H. Hassan, Dina Hussein Mobark, Nagwan Ibrahim Rashwan

“…Background: IRIDA is an inherited recessive anaemia caused by a defect in the TMPRSS6 gene, which codes for the enzyme matriptase-2. This transmembrane serine protease suppresses hepcidin production, an iron regulator (suppressing intestinal absorption of iron). …”
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Sulfurous Gases As Biological Messengers and Toxins: Comparative Genetics of Their Metabolism in Model Organisms by Neal D. Mathew, David I. Schlipalius, Paul R. Ebert

“…Interestingly, D. melanogaster and Arthropoda in general, lack a gene for 3-mercaptopyruvate sulfurtransferase, an enzym for H2S synthesis under reducing conditions.…”
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Graph-theoretic conditions for zero-eigenvalue Turing instability in general chemical reaction networks by Maya Mincheva, Gheorghe Craciun

“…The technique is illustrated with a model of a bifunctional enzyme.…”
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In Vitro Effect of Aqueous Extract and Fraction IV Portion of Ximenia americana Stem Bark on Trypanosoma congolense DNA by Victor Ambrose Maikai, Beatty Viv Maikai, Patricia Ishyaku Kobo

“…The DNA of the trypanosomes was isolated and digested using ECOR1 enzyme and subsequently PCR was carried out. Results showed that aqueous extract and fraction IV portion immobilized 55% and 90% of the trypanosomes after 30-minute incubation. …”
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Dynamic Production of Soluble Extracellular Polysaccharides by Streptococcus mutans by Eva-Maria Decker, Ilka Dietrich, Christian Klein, Christiane von Ohle

“…Microtiter well plates were coated with cell-free supernatants followed by the addition of labeled Concanavalin-A and enzyme substrate. The substrate reactions were kinetically detected at 405 nm. …”
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Early Renal Involvement in a Girl with Classic Fabry Disease by Fernando Perretta, Norberto Antongiovanni, Sebastián Jaurretche

“…Fabry disease is an X-linked lysosomal storage disorder resulting from the deficiency or absence of the enzyme alpha galactosidase A; this defect leads to the systemic accumulation of globotriaosylceramide and its metabolites. …”
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Fucofuroeckol-A from Eisenia bicyclis Inhibits Inflammation in Lipopolysaccharide-Induced Mouse Macrophages via Downregulation of the MAPK/NF-κB Signaling Pathway by Sang-Hoon Lee, Sung-Hwan Eom, Na-Young Yoon, Moon-Moo Kim, Yong-Xin Li, Sang Keun Ha, Se-Kwon Kim

“…FF suppressed the production of nitric oxide (NO) and prostaglandin E2 (PGE2) and the expression of inducible nitric oxide synthase and cyclooxygenase-2 dose dependently in lipopolysaccharide- (LPS-) induced RAW 264.7 mouse macrophages. An enzyme-linked immunosorbent assay and cytometric bead array assay demonstrated that FF significantly reduced the production of proinflammatory cytokines, such as interleukin-6 and tumor necrosis factor-α, and that of the monocyte chemoattractant protein-1. …”
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