Evaluation of Humoral Immunity to Mycobacterium tuberculosis-Specific Antigens for Correlation with Clinical Status and Effective Vaccine Development by Mamiko Niki, Maho Suzukawa, Shunsuke Akashi, Hideaki Nagai, Ken Ohta, Manabu Inoue, Makoto Niki, Yukihiro Kaneko, Kozo Morimoto, Atsuyuki Kurashima, Seigo Kitada, Sohkichi Matsumoto, Koichi Suzuki, Yoshihiko Hoshino

“…However, the recent failure of a clinical trial for a booster BCG vaccine and increasing evidence of antibody-mediated immunity prompted us to evaluate humoral immunity to Mtb-specific antigens. Using Enzyme-Linked ImmunoSpot and Enzyme-Linked ImmunoSorbent Assays, we observed less correlation of both CMI and IgG titers with patient clinical status, including serum concentration of C reactive protein. …”
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Nonalcoholic Fatty Liver Disease in Canadian First Nations and Non-First Nations Patients by Julia Uhanova, Gerald Minuk, Federico Lopez Ficher, Natasha Chandok

“…There were no significant differences in liver enzyme or function tests in either cohort after approximately three years of follow-up. …”
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Stability and neurotoxic impact of organophosphate pesticides in aqueous environments by Vladan J. Anićijević, Tamara Tasić, Vedran Milanković, Radovan M. Karkalić, Tamara D. Lazarević Pašti

“…Their acute toxicity is ascribed to inhibiting acetylcholinesterase (AChE), a key enzyme in the transmission of nerve impulses in animals. …”
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Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress... by Ágnes Szabó, Zsolt Galla, Eleonóra Spekker, Mónika Szűcs, Diána Martos, Keiko Takeda, Kinuyo Ozaki, Hiromi Inoue, Sayo Yamamoto, József Toldi, Etsuro Ono, László Vécsei, Masaru Tanaka

“…Little is known about the consequences of deleting the KYN enzyme gene. …”
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Functional and Structural Consequences of Nine CYP21A2 Mutations Ranging from Very Mild to Severe Effects by Débora de Paula Michelatto, Leif Karlsson, Ana Letícia Gori Lusa, Camila D’Almeida Mgnani Silva, Linus Joakim Östberg, Bengt Persson, Gil Guerra-Júnior, Sofia Helena Valente de Lemos-Marini, Michela Barbaro, Maricilda Palandi de Mello, Svetlana Lajic

“…Mutated proteins were transiently expressed in COS-1 cells and enzyme activities towards 17-hydroxyprogesterone and progesterone were determined. …”
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The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats by Xianbao Liu, Hong Zhan, Xu Zeng, Chunfang Zhang, Dunjin Chen

“…We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. …”
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Effectiveness of the PSI BLAST algorithm in dependence on scanning word size by Mindaugas Margelevičius, Albertas Timinskas

“…We also accomplish statistical analysis for each enzyme of the cytosine-5 methyltransferase family after we apply alignment searching for the biologically related protein sequences. …”
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Synthesis of Galactosyl Mannitol Derivative Using β-Galactosidase from Kluyveromyces lactis by Klewicki Robert, Belina Iwona, Wojciechowska Aleksandra, Klewicka Elżbieta, Sójka Michał

“…The use of the enzyme dose ranging from 2850 to 11,400 LAU/100 g lactose allowed obtaining gal-mannitol at the level of 21.8% total saccharides; higher doses intensified product decomposition. …”
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Prolactin Is a Strong Candidate for the Regulation of Luteal Steroidogenesis in Vizcachas (Lagostomus maximus) by S. Proietto, S. A. Cortasa, M. C. Corso, P. I. F. Inserra, S. E. Charif, A. R. Schmidt, N. P. Di Giorgio, V. Lux-Lantos, A. D. Vitullo, V. B. Dorfman, J. Halperin

“…Remarkably, the P4-sinthesizing enzyme 3β-HSD accompanied the expression pattern of PRLR/LHR throughout gestation. …”
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Regulatory mechanism of carbohydrate metabolism pathways on oil biosynthesis of oil plant Symplocos paniculata by Wenbin Zeng, Beilei Xie, Yunzhu Chen, Jingzhen Chen, Peiwang Li, Lijuan Jiang, Changzhu Li, Qiang Liu, Yan Yang

“…Remarkably, during the initial phase of fruit development from 10 to 90 days after flowering (DAF), pivotal genes involved in starch biosynthesis, such as ADP-glucose pyrophosphorylase (AGP), starch synthase (SS), and starch branching enzyme (SBE), facilitated an earlier accumulation of starch within the fruit. …”
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Effect on Soil Properties of BcWRKY1 Transgenic Maize with Enhanced Salinity Tolerance by Xing Zeng, Yu Zhou, Zhongjia Zhu, Hongyue Zu, Shumin Wang, Hong Di, Zhenhua Wang

“…There was no change in the rhizosphere soils of either WL-73 or WT plants in the four soil enzyme activities, seven soil physicochemical properties, and the populations of three soil organisms. …”
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Mitochondrial Thioredoxin-Glutathione Reductase from Larval Taenia crassiceps (Cysticerci) by Alberto Guevara-Flores, Irene P. del Arenal, Guillermo Mendoza-Hernández, Juan Pablo Pardo, Oscar Flores-Herrera, Juan L. Rendón

“…Thioredoxin from eukaryotic sources was accepted as substrate. The enzyme reduced H2O2 in a NADPH-dependent manner, although with low catalytic efficiency. …”
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Mechanistic insights toward progress in alogliptin beyond glycemic control: translational perspective by Faraha Ahmed, Syed Sufian Ahmad, M. Mumtaz Alam, M. Shaqiquzzaman, Abul Kalam Najmi, Mohammad Ahmed Khan

“…Abstract Background Alogliptin belongs to gliptin family of drugs that inhibits ubiquitous enzyme dipeptidyl peptidase-4 (DPP-4). Gliptins increase the life-span of incretin hormones that appear to benefit functioning of several organs via various signaling pathways. …”
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Chromosome-Level Genome Assembly and Annotation of the Highly Heterozygous <i>Phallus echinovolvatus</i> Provide New Insights into Its Genetics by Mengya An, Ruoxi Liang, Yanliu Chen, Jinhua Zhang, Xiuqing Wang, Xing Li, Guohua Qu, Junfeng Liang

“…The Monop had a size of 36.54 Mb, with 10,251 predicted protein-coding genes and including 433 carbohydrate-active enzyme genes, 385 cytochrome P450 enzyme genes, and 42 gene clusters related to secondary metabolite synthesis. …”
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Physiology of Glyphosate-Resistant and Glyphosate-Susceptible Palmer Amaranth (Amaranthus palmeri) Biotypes Collected from North Carolina by Jared R. Whitaker, James D. Burton, Alan C. York, David L. Jordan, Aman Chandi

“…These results also are consistent with resistance being due to increased gene copy number for the target enzyme.…”
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The effect of silver nitrate on the alkaline phosphatase activity, TNF and IL-10 gene expression; Experimental and computational studies by Nader jadid, Ali Asghar Moshtaghie, Hashem Nayeri, Masoud Foladgar, Maryam Ostadsharif

“…The research employed enzyme-linked immunosorbent assay (ELISA) techniques to quantify IL-10 and TNF-α levels using serum assay kits. …”
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Effects of different microplastics on the physicochemical properties and microbial diversity of rice rhizosphere soil by Sheng Lai, Sheng Lai, Sheng Lai, Cunzhong Fan, Ping Yang, Ping Yang, Yuanyuan Fang, Yuanyuan Fang, Lanting Zhang, Lanting Zhang, Minfei Jian, Guofei Dai, Guofei Dai, Jutao Liu, Jutao Liu, Huilin Yang, Liqin Shen, Liqin Shen

“…Microplastics also decreased soil enzyme activity, with aging-PLA having a somewhat stimulatory effect on enzyme activity compared to PLA. …”
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Characterization of Cellulolytic Bacterial Cultures Grown in Different Substrates by Mohamed Idris Alshelmani, Teck Chwen Loh, Hooi Ling Foo, Wei Hong Lau, Awis Qurni Sazili

“…Results showed that Bacillus amyloliquefaciens 1067 DSMZ, Bacillus megaterium 9885 ATCC, Paenibacillus curdlanolyticus 10248 DSMZ, and Paenibacillus polymyxa 842 ATCC produced higher enzyme activities as compared to other bacterial cultures grown on different substrates. …”
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Comparative Modeling and Molecular Dynamics Simulation of Substrate Binding in Human Fatty Acid Synthase: Enoyl Reductase and β-Ketoacyl Reductase Catalytic Domains by Arun John, Vetrivel Umashankar, Subramanian Krishnakumar, Perinkulam Ravi Deepa

“…Fatty acid synthase (FASN, EC 2.3.1.85), is a multi-enzyme dimer complex that plays a critical role in lipogenesis. …”
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Molecular biological research and molecular homologous modeling of Bw.03 subgroup by WANG Li, KONG Yongkui, JIN Huifang, LIU Xin, XIE Ying, LIU Xue, CHANG Yanli, WANG Yafang, YANG Shumiao, ZHU Di, YANG Qiankun

“…The intermolecular force analysis can explain the root cause of enzyme activity weakening.…”
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