Anderson–Fabry Disease: From Endothelial Dysfunction to Emerging Therapies by Cosimo A. Stamerra, Rita Del Pinto, Paolo di Giosia, Claudio Ferri, Amirhossein Sahebkar

“…In contrast, enzyme replacement and chaperone therapies are already fully available to patients and allow substantial amelioration of quality and quantity of life. …”
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Renin-Angiotensin System Inhibitors in COVID-19: Current Concepts by Kunal Mahajan, Prakash Chand Negi, Neeraj Ganju, Sachin Sondhi, Naresh Gaur, Rao Somendra

“…The functional receptor to SARS-CoV-2, the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, is angiotensin-converting enzyme-2 (ACE-2), the same enzyme that physiologically counters the renin-angiotensin system (RAS) activation. …”
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Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation by Marcia L. Moss, Dmitry Minond

“…Since its discovery, ADAM17, also known as TNFα converting enzyme or TACE, is now known to process over 80 different substrates. …”
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Estimacão da qualidade industrial da batata (Solanum tuberosum L.) atraves do uso da isoenzima glutamato oxaloacetato transaminase by M.A. Andreu, A. da S. Pereira

“…Results of the comparisons indicated a significant association between the 1.00 band of the evaluated enzyme and the chips color, which allowed an early estimation by this enzyme of the effect of frying. …”
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Fabry Disease and Early Stroke by U. Feldt-Rasmussen

“…Both males and females can be safely treated with enzyme replacement; and thus screening for Fabry disease of young stroke populations should be considered. …”
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Simultaneously Recovering High-Purity Chromium and Removing Organic Pollutants from Tannery Effluent by Jie Zong, Yan-Chun Li, Kang Hu

“…In this work, high recovery rate and high purity of the chromium ion were successfully prepared by the way of acid enzyme, flocculant, and Fenton oxidation. The experiments were characterized by TG, TOC, UV-VIS, and SEM. …”
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Synthesis and Docking Studies of the Novel N-(2,2-Di(1H-pyrrol-2-yl)ethyl)adamantane-1-carboxamide, a Potential 11β-HSD1 Inhibitor by Salvador Gallardo-Alfonzo, Ana Lilia Ocampo-Néstor, Claudia Contreras-Celedón, Luis Chacón-García

“…Docking studies with 11β-HSD1 revealed favorable binding interactions with the enzyme.…”
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Inulin supplementation in feed as a prebiotic for red tilapia Oreochromis sp. by Agustina Agustina, Adi Susanto

“… The objective of this study was to assess the impact of inulin as a prebiotic in feed on red tilapia (Oreochromis sp.) growth performance, hematological parameters, feed utilization, digestive enzyme activity, and the quantity of lactic acid bacteria in the intestine. …”
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Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway by Mohammed M. Safhi, Mohammad Firoz Alam, Sivagurunathan Moni Sivakumar, Tarique Anwer

“…Exposure to the MESM tremendously modulated the levels of hepatic enzyme markers ALP, ACP, ALT, and AST in Groups 3 and 4. …”
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Role of RING-Type E3 Ubiquitin Ligases in Inflammatory Signalling and Inflammatory Bowel Disease by Liguo Zhu, Ying Li, Longyuan Zhou, Guang Yang, Ying Wang, Jing Han, Li Li, Shenghong Zhang

“…It includes the ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), and ubiquitin ligase (E3). …”
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Stimulators and Activators of Soluble Guanylate Cyclase: Review and Potential Therapeutic Indications by Bobby Nossaman, Edward Pankey, Philip Kadowitz

“…The heme-protein soluble guanylyl cyclase (sGC) is the intracellular receptor for nitric oxide (NO). sGC is a heterodimeric enzyme with α and β subunits and contains a heme moiety essential for binding of NO and activation of the enzyme. …”
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Identification of New Potential APE1 Inhibitors by Pharmacophore Modeling and Molecular Docking by In Won Lee, Jonghwan Yoon, Gunhee Lee, Minho Lee

“…Based on these processes, we ultimately identified 1,338 potential inhibitors of APE1 with predicted binding affinities to the enzyme.…”
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Complexes of a piperazine based macrocycle as Cu-Zn SOD biomimetic: approach by constants determination by Armando Ferrer Serrano, Ilena Alica García Del Toro

“… Obtaining new compounds capable of catalyzing the dismutation reaction of the superoxide anion carried out by the enzyme Cu,Zn-SOD has become a topic of great interest. …”
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Generation of a transgene-free Induced pluripotent stem (iPS) cell line (JNCHi002-A) from a female heterozygous carrier of the low density lipoprotein receptor (LDLR) gene mutation... by Rujin Tian, Yixiao Li, Hongmei Xin, Yue Jiang, Haozheng Zhang, Lin Zhong, Zhongtao Gai, Qianqian Deng, Chunhui Wang, Kaihui Zhang

“…This enzyme serves as the rate-limiting step in the biosynthesis of cholesterol. …”
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An Unusual Case of Gullo’s Syndrome Concomitant with Serious Endometriosis Disease in a Postmenopausal Woman by Abdelhakim Ainahi, Abdellaziz Ziane, Lahcen Wakrim, Naima Elmdaghri, Abdelhamid Barakat

“…Gullo’s syndrome is a singular physiological phenomenon defined by an abnormal increase in serum pancreatic enzyme levels that may occur in healthy subjects in the absence of pancreatic disorders. …”
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TMPRSS2 as a Key Player in Viral Pathogenesis: Influenza and Coronaviruses by Gilmara Barros de Lima, Everton Nencioni, Fábio Thimoteo, Camila Perea, Rafaela Fuzaro Alves Pinto, Sergio Daishi Sasaki

“…TMPRSS2, a human transmembrane protease enzyme, plays a crucial role in the spread of certain viruses, including influenza and coronaviruses. …”
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Flavocoxid, a Nutraceutical Approach to Blunt Inflammatory Conditions by Alessandra Bitto, Francesco Squadrito, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Anna Mecchio, Federica Galfo, Domenica Altavilla

“…Flavocoxid is a mixed extract containing baicalin and catechin and it acts as a dual balanced inhibitor of cyclooxygenase-1 (COX-1) and COX-2 peroxidase enzyme activities with a significant inhibition of 5-lipoxygenase (5-LOX) enzyme activity in vitro. …”
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Captopril-Associated Cough Is Not due to Increased Airway Responsiveness by SP Blackie, C Hilliam, R Porter, R Rangno, PD Paré

“…BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors commonly cause cough. There is controversy as to whether preexisting airway hyperresponsivencss predisposes patients to ACE inhibitor-induced cough and whether ACE inhibitor therapy can cause airway hypcrresponsiveness.…”
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Effect of Vandetanib Treatment on Cystic Changes in the Liver following Metastasis from Medullary Thyroid Carcinoma by Ai Matsui, Soji Toda, Daisuke Murayama, Hiroyuki Iwasaki

“…The liver enzyme levels improved after replacing vandetanib with lenvatinib treatment. …”
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Evaluation of Neuraminidase Inhibitory Activity of Compounds and Extracts from Traditional Medicines by HPLC-FLD by Guangying Yu, Dan Fang

“…It was found that the results of most compounds except for the auto fluorescence substances determined by HPLC-FLD were in good agreement with NA enzyme-based inhibitory assays. Comparing to traditional NA enzyme-based inhibitory assays, the HPLC-FLD method could prevent interference from fluorescence pigments of compounds. …”
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