Protocol for differentiating cardiomyocytes and generating engineered heart tissues from human feeder-free extended pluripotent stem cells by Zhongjun Wan, Shanshan Wen, Ran Zheng, Li Li, Wei Jiang, Donghui Zhang

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Altered Thyroid Function Tests Observed in Hypophosphatasia Patients Treated with Asfotase Alfa by Hajime Kato, Naoko Hidaka, Minae Koga, Yuka Kinoshita, Masaomi Nangaku, Noriko Makita, Nobuaki Ito

“…After the initiation of asfotase alfa, three HPP patients showed low free triiodothyronine (FT3) and free thyroxine (FT4) measured with AIA-2000 (Tosoh, Tokyo, Japan), an enzyme immunoassay system that uses ALP as a labeling enzyme, but their thyroid-stimulating hormone (TSH) levels were within the normal range. …”
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Production of an Extract with β-1,4-Xylanase Activity by <i>Fusarium oxysporum</i> f. sp. <i>melonis</i> on a Sonicated Brewer’s Spent Grain Substrate by Irma A. Arreola-Cruz, Rosalba Troncoso-Rojas, Francisco Vásquez-Lara, Nina G. Heredia-Sandoval, Alma R. Islas-Rubio

“…<i>F. oxysporum</i> grown on lignocellulosic substrates under submerged conditions produces an extracellular enzyme profile with hemicellulolytic and cellulolytic activities. …”
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Efek Pemberian Suntikan Subkutan Vitamin C Terhadap Luka Insisi Dermal by Surya Darma, Menker Manjas, Deddy Saputra, Salmiah Agus, Erkadius Erkadius

“…<p>Abstrak Vitamin C berfungsi sebagai kofaktor enzyme prolil dan lysil hydroxilase. Enzym tersebut berfungsi dalam proses hidroksilasi yang membentuk ikatan hidroksiprolin dan hidroksilisin pada fibroblast dalam membentuk kolagen. …”
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Efek Pemberian Suntikan Subkutan Vitamin C Terhadap Luka Insisi Dermal by Surya Darma, Menkher Manjas, Deddy Saputra, Salmiah Agus, Erkadius .

“…Abstrak Vitamin C berfungsi sebagai kofaktor enzyme prolil dan lysil hydroxilase. Enzym tersebut berfungsi dalam proses hidroksilasi yang membentuk ikatan hidroksiprolin dan hidroksilisin pada fibroblast dalam membentuk kolagen. …”
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Optimized extraction and kinetic study of cholesterol oxidase from a newly isolated Escherichia fergusonii strain from local whey samples: insights through a combined experimental... by Simin Khataee, Gholamreza Dehghan, Samaneh Rashtbari, Arezu Marefat, Sina Jamei, Hamed Farzi-Khajeh

“…Furthermore, the ChoX enzyme revealed acceptable stability at a pH value of 6.5 to 8.5, maintaining its initial activity of more than 50.0%. …”
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Effects of the Treatment Technology of Soybean on Volatile Flavor Compounds of Plant-based Compound Milk during Storage by Xue WANG, Youqiang YU, Xiaoyang ZHENG, Hongjiang MA, Shiwei LIU, Wenxin WANG, Fang ZHOU, Shenglin DUAN

“…Headspace solid-phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS) combined with electronic nose and human sensory evaluation were used to analyze the differences of volatile flavor substances in the plant-based compound milk, that prepared by two soybean treatment technologies (oxygen separation grinding/enzyme inactivation with high temperature, grinding after enzyme inactivation) at different storage time (0, 90, 180 and 360 d). …”
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Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip... by Garland Kgosi More, Nolitha Nkobole, Charmy Twala, Sechaba Machedi, Tebogo Amos Moswetsa, Ramakwala Christinah Chokwe

“…Methods: In vitro antidiabetic activity was tested with α-amylase enzyme inhibition method and antioxidant activity was evaluated. …”
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Copious Podocyturia without Proteinuria and with Normal Renal Function in a Young Adult with Fabry Disease by H. Trimarchi, R. Canzonieri, A. Muryan, A. Schiel, A. Araoz, M. Forrester, A. Karl, F. Lombi, J. Andrews, V. Pomeranz, T. Rengel, E. Zotta

“…The time for starting a patient with Fabry disease on enzyme replacement therapy is still a matter of debate, particularly when no overt classical clinical signs or symptoms are present. …”
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Mucopolysaccharidosis: A rare case from ophthalmology perspective by Santosh Singh Patel, Rajesh Kumar Sahu, Reshu Malhotra, Anju Bhaskar, A. K. Chandrakar

“…Newer treatment modalities such as hematopoietic stem cell transplantation and enzyme-replacement therapy have increased the life span of many MPS patients and created the need to improve the management of ocular symptoms.…”
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Characterization of Thermo- and Detergent Stable Antigenic Glycosylated Cysteine Protease of Euphorbia nivulia Buch.-Ham. and Evaluation of Its Ecofriendly Applications by Shamkant B. Badgujar, Raghunath T. Mahajan

“…The enzyme can also be used for silver recovering from X-ray plates. …”
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A Novel Method to Prepare PolyGMA and its Application to Immobilization of β-Galactosidase by Sun Sufang, Dong Lingyun

“…The conclusion obtained indicated that the ployGMA prepared concurrently with liquid and solid porogen was more suitable to immobilize enzyme because of the much more porous surface structure obtained.…”
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How a gene fuels ear infections by Sedigheh Delmaghani, Aziz El-Amraoui

“…The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.…”
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Bio-active composition, antibacterial activity and molecular docking studies of Salicia nitida (Benth.) root extracts by Wisdom U. Ike, Okereke C. Stanley, Nosiri Ijeoma, Okamgba C. Okezie, Nwokocha W. Osita, Aguwanba Chinedu, Aaron C. Friday

“…Molecular docking simulations revealed valuable insights into the potential interactions between Class A beta-lactamase enzyme (PDB: 3BLM) with Butylated hydroxytoluene (CID: 31404) and 5-Eicosene (CID: 5364600). …”
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Ultrasonication-assisted lipase-catalyzed esterification of chlorogenic acid: A comparative study using fatty alcohol and acids in solvent and solvent-free conditions by Chia-Hung Kuo, Parushi Nargotra, Tsung-Han Lin, Chwen-Jen Shieh, Yung-Chuan Liu

“…Despite optimization of factors including molar ratio, enzyme dosage, and reaction time, the highest conversion rate achieved was of only 36.8 %. …”
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Сhanges in subcellular distribution of lysosomal cysteine proteinases activity in parenchymatous organs of rats under the action of nitric oxide synthesis modulators by M. A. Fomina, A. A. Terent'ev

“…The revealed changes are associated with the signs of changes in the ratio of pro-enzyme and active forms of cathepsins.Conclusion. …”
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Phytoremediation of Oil-Contaminated Soil by <i>Tagetes erecta</i> L. Combined with Biochar and Microbial Agent by Xin Fang, Pufan Zheng, Haomin Wang, Kefan Wang, Cong Shi, Fuchen Shi

“…Compared with the treatments with biochar, the chlorophyll fluorescence parameter NPQ_Lss and plant antioxidant enzyme activities significantly decreased in the treatments applied with the microbial agent, while soil enzyme activities, especially oxidoreductase activities, significantly increased. …”
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The effects of Fe2O3 nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role by Samaneh Rashtbari, Zahra Hassanpour Aydinlou, Leila Sadeghi

“…Acetylcholinesterase (AChE) is a cholinergic enzyme in central and peripheral nervous systems. …”
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Design and assessment of lipase-CuO nanoparticle conjugates for enhanced antimicrobial efficacy against clinical pathogens by Eman M. Handak, Dina H. Amin, Mai M. Elhateir

“…Statistical optimization of lipase enzyme was done using a Plackett-Burman design giving two enhancement models for lipase production with increasing in productivity up to 143.43% (2800 U/ml). …”
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Hyperglycemia in Streptozotocin-Induced Diabetes Leads to Persistent Inflammation and Tissue Damage Following Uveitis Due to Reduced Levels of Ciliary Body Heme Oxygenase-1 by Settimio Rossi, Michele D'Amico, Annalisa Capuano, Mary Romano, Pasquale Petronella, Clara Di Filippo

“…STZ-hyperglycemic rats had impaired levels of the enzyme HO-1 within the ciliary bodies if compared with the nondiabetic rats. …”
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