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2061
Arginase Inhibitor in the Pharmacological Correction of Endothelial Dysfunction
Published 2011-01-01“…Because of the high activity of arginase enzyme which catalyzes the hydrolysis of L-arginine into ornithine and urea, the bioavailability of nitrogen oxide decreases. …”
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2062
Full-length inhibitor protein is the most effective to perturb human dUTPase activity
Published 2025-02-01“…Abstract It has been demonstrated recently that knockout of the dUTPase enzyme leads to early embryonic lethality in mice. …”
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2063
Exploring EPR Parameters of 187Re Complexes for Designing New MRI Probes: From the Gas Phase to Solution and a Model Protein Environment
Published 2022-01-01“…Furthermore, a docking study of ReABT at the enzyme PI3K active site and Aiso calculations of ReABT in the enzyme environment were carried out. …”
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2064
Prevalence and Clinical Spectrum of Liver Disease in Nepalese HIV-Sero-Positive Patients Undergoing Antiretroviral Therapy: A Cross-Sectional Hospital Based Study
Published 2017-01-01“…Introduction. Liver enzyme abnormalities are common in HIV patients, and the prevalence varies across the nations. …”
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2065
Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds
Published 2025-01-01“…The antimicrobial and tyrosinase enzyme inhibition activities of various extracts and isolated compounds of Limonium meyeri were investigated. …”
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2066
NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots
Published 2018-01-01“…Urease enzyme is responsible for gastric cancer, peptic ulcer, hepatic coma, and urinary stones in millions of people across the world. …”
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2067
Phospholipase A2 Activity in Gingival Crevicular Fluid from Patients with Periodontal Disease: A possible Marker of Disease Activity
Published 1994-01-01“…When the BOP positive sites became negative after periodontal therapy, the enzyme activity decreased dramatically to almost undetectable levels. …”
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2068
Successful Erlotinib Treatment for a Patient with Gefitinib-Related Hepatotoxicity and Lung Adenocarcinoma Refractory to Intermittently Administered Gefitinib
Published 2011-01-01“…The patient was treated with gefitinib for 6 weeks until he developed substantially elevated hepatic enzyme levels that resulted in the discontinuation of gefitinib. …”
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2069
Tyrosine hydroxylase of the brain and it’s regulation by glucocorticoids
Published 2016-05-01“…Moreover, our treatment led to increase in TH mRNA levels in 25- and 70-day-old animals, as well as an increase in enzyme activity in the brainstem and cerebral cortex of adult rats. …”
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2070
TẠO DÒNG VÀ BIỂU HIỆN GEN nahC MÃ HÓA 1,2-dihydroxynaphthalene dioxygenase CỦA VI KHUẨN Paenibacillus naphthalenovorans 4B1
Published 2024-09-01“…Kết quả này là cơ sở cho việc nghiên cứu tinh sạch và xác định các đặc tính của enzyme. …”
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2071
Enterokinase deficiency associated with novel TMPRSS15 gene mutations: a case report
Published 2025-01-01“…Further, early pancreatic enzyme supplementation is a clinical strategy which can achieve satisfactory outcomes.…”
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2072
The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
Published 2016-01-01“…There are two switches: an E3 ubiquitin ligase enzyme that tags ubiquitin molecules to the target proteins for proteolysis and a second enzyme, the deubiquitinating enzyme (DUBs), that performs the opposite action, thereby preventing proteolysis. …”
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2073
Sialidase NEU3 dynamically associates to different membrane domains specifically modifying their ganglioside pattern and triggering Akt phosphorylation.
Published 2014-01-01“…Sialidase NEU3 shows high enzymatic specificity toward gangliosides. Moreover, the enzyme is present both at the cell surface and in endosomal structures and cofractionates with caveolin. …”
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2074
Adsorption of peroxidase from L onto alginate–guar gum matrix: Kinetic, equilibrium and thermodynamic analysis
Published 2016-07-01“…The experimental data fitted to the Freundlich model in agreement with the low energy activation, demonstrating the presence of a high physical and unspecific interaction between the enzyme and the matrix.…”
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2075
Enhanced Production and Characterization of a Solvent Stable Amylase from Solvent Tolerant Bacillus tequilensis RG-01: Thermostable and Surfactant Resistant
Published 2014-01-01“…The enzyme was also stable in the presence of SDS, Tween-40, Tween-60, and Tween-80 (1%) and was found stimulatory effect, respectively. …”
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2076
Antioxidant capacity in leaves of pear cultivars during the summer season
Published 2023-07-01“…The control European cultivar ‘Williams’ had a lower level of enzyme activity in the summer of 2021, compared to the Russian cultivars ‘Lyuberskaya’ and ‘Flamenco’. …”
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2077
Physicochemical and Morphological Characterization of Potato Starch Modified by Bacterial Amylases for Food Industry Applications
Published 2018-01-01“…Induction of enzyme preparations allowed obtaining starches characterized by extended solubility and water-sorption ability and also lower gelation temperatures and viscosity. …”
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2078
The Effect of Clopidogrel and Ticagrelor on Human Adipose Mesenchymal Stem Cell Osteogenic Differentiation Potential: In Vitro Comparative Study
Published 2024-01-01“…In comparison to all study groups, the TICA group showed significant increase in the mineralized extracellular matrix, ALP enzyme activity, and bone markers expression as RUNX2 (P<0.0001), OC, and OPG (P<0.05). …”
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2079
Characterization of the algC Gene Expression Pattern in the Multidrug Resistant Acinetobacter baumannii AIIMS 7 and Correlation with Biofilm Development on Abiotic Surface
Published 2014-01-01“…Cloning, heterologous expression, and bioinformatics analyses indicated algC gene product as the bifunctional enzyme phosphomannomutase/phosphoglucomutase (PMM/PGM) of ∼53 kDa size, which augmented biofilms significantly in algC clones compared to controls (lacking algC gene), further localized by scanning electron microscopy. …”
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2080
Comparative chemical investigation and evaluation of antioxidant and tyrosinase inhibitory effects of Withania somnifera (L.) Dunal and Solanum nigrum (L.) berries
Published 2018-03-01“…The highest inhibition of tyrosinase enzyme was also exhibited by WSEA and SNEA (59.6 and 58.7 %) resp. …”
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