Rapid Screening and Estimation of Binding Constants for Interactions of Fe3+ with Two Metalloproteins, Apotransferrin and Transferrin, Using Affinity Mode of Capillary Electrophore... by Mohammed Al Bratty, Hassan A. Alhazmi, Sadique A. Javed, Zia Ur Rehman, Asim Najmi, Karam A. El-Sharkawy

“…The present study may be used as a reference for the investigation of protein-metal ion, drug-protein, drug-metal ion, and enzyme-metal ion interactions and may be helpful to provide preliminary insight into the new metal-based drug development.…”
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Inhibition of Cathepsin S Produces Neuroprotective Effects after Traumatic Brain Injury in Mice by Jianguo Xu, Handong Wang, Ke Ding, Xinyu Lu, Tao Li, Jiawei Wang, Chunxi Wang, Jian Wang

“…It has long been regarded as an enzyme that is primarily involved in general protein degradation. …”
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Leptin Promoted IL-17 Production from ILC2s in Allergic Rhinitis by Yanhui Wen, Qingxiang Zeng, Xi Luo, Renqiang Ma, Yiquan Tang, Wenlong Liu

“…Serum leptin levels were measured, and their correlation with the frequency of IL-17+ ILC2 cells was analyzed using enzyme-linked immunosorbent assay (ELISA) and flow cytometry. …”
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Immunomodulatory effect of hepatitis B virus (HBV) antigens and MRSA antigens on immune response by Entidhar A. Hadi, Mohammad Abd-Kadhum Al-Saadi, Kaiser N. Madlum

“…The immune response against MRSA somatic antigens was assessed by measurement of interferon-γ, interleukin-4, and interleukin-5 by enzyme-linked immunosorbent assay technique. Results: The results indicated a significant increase (P < 0.05) in the mean value of IFN-γ in group II (125.9995 pg/mL) and III group (133.6504 pg/mL) and group IV (132.0271 pg/mL) as compared with control (group I) (49.6203 pg/mL). …”
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In Vitro and In Silico Cytotoxic and Antibacterial Activities of a Diterpene from Cousinia alata Schrenk by Almira Zhanzhaxina, Yerlan Suleimen, Ahmed M. Metwaly, Ibrahim H. Eissa, Eslam B. Elkaeed, Raigul Suleimen, Margarita Ishmuratova, Kydyrmolla Akatan, Walter Luyten

“…The presence of the essential pharmacophoric features of histone deacetylase (HDAC) inhibitors in the structure of grindelic acid encouraged us to run a molecular docking study against the HDAC enzyme to understand its mechanism of action on a molecular level. …”
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Seroprevalence of Peste des Petits Ruminants and Contagious Caprine Pleuropneumonia Coinfections in Goats in Kwale County, Kenya by George Lugonzo, George Gitao, Lilly Bebora, Harrison Osundwa Lutta

“…Herein, the competitive enzyme-linked immunosorbent assay (cELISA) and the latex agglutination test (LAT) were used to determine the coinfections of PPR and CCPP in goats in Kwale County on Kenya’s South Coast. …”
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Seroprevalence and Risk Factors of Toxoplasma gondii Infection among Domestic Ruminants in East Hararghe Zone of Oromia Region, Ethiopia by Berhanu Tilahun, Yacob Hailu Tolossa, Getachew Tilahun, Hagos Ashenafi, Shihun Shimelis

“…Sera of 1360 domestic ruminants were analyzed for the presence of anti-T. gondii IgG antibodies using the indirect enzyme-linked immunosorbent assay (iELISA). Additionally, the owners were also interviewed using a structured questionnaire to identify the potential risk factors of T. gondii infection. …”
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Effect of Locally Delivered Melatonin as an Adjunct to Nonsurgical Therapy on GCF Antioxidant Capacity and MMP-9 in Stage II Periodontitis Patients: A Randomized Controlled Clinica... by Enji Ahmed, Olfat G. Shaker, Nermin Yussif, Dalia M. Ghalwash

“…Total antioxidative capacity (TAC) and matrix metalloproteinase-9 (MMP-9) levels in GCF were also evaluated utilizing commercially available enzyme-linked immunosorbent assay kits (ELISA) at baseline and 3 months after therapy. …”
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Do Salivary <i>Cullin7</i> Gene Expression and Protein Levels Provide Advantages over Plasma Levels in Diagnosing Breast Cancer? by Ceren Tilgen Yasasever, Derya Duranyıldız, Süleyman Bademler, Hilal Oğuz Soydinç

“…Protein levels of blood and saliva samples taken from breast cancer patients and a healthy control group were measured by the ELISA (Enzyme-Linked Immunosorbent Assay) method. Gene expression levels between the two groups were analyzed by the qPCR (quantitative Polymerase Chain Reaction) method. …”
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Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration by Susanne W. Bruun, Knud Josefsen, Julia T. Tanassi, Aleš Marek, Martin H. F. Pedersen, Ulrik Sidenius, Martin Haupt-Jorgensen, Julie C. Antvorskov, Jesper Larsen, Niels H. Heegaard, Karsten Buschard

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Comparison of Antioxidant and Alpha-Glucosidase Inhibitory Properties of Moringa peregrina and Ferulago carduchorum Leaf Extracts and Microencapsulation of Superior Plant by Shiva Nouri, Maryam Moslehishad, Seyede Marzieh Hosseini, Mina Etemadi

“…The results showed that the ABTS•+ radical scavenging and α-glucosidase enzyme inhibitory activities of both plants were dependent on extract concentration. …”
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Non-histone lactylation: unveiling its functional significance by Pusong Shi, Yongjie Ma, Yongjie Ma, Yongjie Ma, Yongjie Ma, Yongjie Ma, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang, Shaolu Zhang

“…Notably, this modification is catalyzed by lactyltransferase and reversed by delactylase, with numerous new enzymes, such as AARS1/2, reported to be involved. …”
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Piezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity by Radka Obořilová, Eliška Kučerová, Tibor Botka, Hana Vaisocherová-Lísalová, Petr Skládal, Zdeněk Farka

“…The sensor, a QCM chip modified with the bacterium S. aureus RN4220 ΔtarM, was utilized to monitor the activity of the enzyme lysostaphin and the phage P68 as model lytic agents. …”
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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…We examined six different groups of breakthrough drugs, selective serotonin reuptake inhibitors, statins, angiotensin-converting-enzyme (ACE) inhibitors, histamine type 2 antagonists, proton pump inhibitors, calcium channel blockers and fluoroquinolones. …”
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Digestion, faeces microbiome, and selected blood parameters in dogs fed extruded food containing Black soldier fly (Hermetia illucens) meal by Kanber Kara, Oğuzhan Kahraman, Fatma İnal, Zekeriya Safa İnanç, Sena Yilmaz Öztaş, M. Selçuk Alataş, Ibrar Ahmed

“…As a result, HI larva meal can be used up to 100% instead of chicken meal in extruded dog food without any negative effects on body weight, digestibility, faecal score, consumption preference, kidney-liver enzyme activities and immunological parameters. Besides, HI larva meal at 7.5% and 15% in extruded dog food had different effects on the faecal microbiome.…”
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Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism by Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist

“…Axotomy lead to a loss of the NAD+ synthesis enzyme NMNAT2 within 2 h and a depletion of NAD+ within 4-6 h. …”
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Mapping the global landscape of chikungunya rapid diagnostic tests: A scoping review. by José Moreira, Patrícia Brasil, Sabine Dittrich, André M Siqueira

“…Diagnostics strategies rely heavily on reverse transcriptase-polymerase chain reaction (RT-PCR) and antibody detection by enzyme-linked Immunosorbent assay (ELISA). Rapid diagnostic tests (RDTs) are available and promise to decentralize testing and increase availability at lower healthcare system levels.…”
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Relationship of Autophagic Dysfunction With the Quality of Life and Sleep, Depression and Disease Severity in Patients With Restless Legs Syndrome by Esen Çiçekli, Hamza Malik Okuyan, Canan Birimoğlu Okuyan, Şeyda Öznur Ayçiçek, Dilcan Kotan

“…All participants were administered the Pittsburgh Sleep Quality Index, the Quality‐of‐Life Scale, and the Beck Depression Inventory. The enzyme‐linked immunosorbent assay was employed to quantify the expressions of ATG3 and ATG5. …”
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Plasma biomarkers for predicting heart failure in patients with acute myocardial infarction by Guihong Rong, Xiao Wang, Xinling Qin, Yanxia Wang, Meilian Quan, Chunfeng Xi

“…We measured the serum biomarkers NT-proBNP, cTNT, PLR, NLR, and GDF-15 in all patients using enzyme-linked immunosorbent assay (ELISA). Subsequently, we performed t-tests to assess the predictive value of these biomarkers for post-AMI HF. …”
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Portrait of WWP1: the current state in human cancer by Jiaming Lei, Jun Chen, Wenwen Yu, Qing Wu, Shuang Jing, Yuanguang Tang, Li Lin, Meichun Hu

“…WWP1, a member of the C2-WW-HECT E3 ligase family, is an E3 ubiquitin-protein ligase containing WW domains. This enzyme plays a critical role in regulating diverse cellular processes. …”
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