Suggested Topics within your search.
Suggested Topics within your search.
-
1701
Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations
Published 2025-03-01“…Insufficient enzyme levels can lead to the progression of motor symptoms, undermining treatment goals. …”
Get full text
Article -
1702
Biochemistry /
Published 2011Table of Contents: “…Carbohydrates, lipids, and amino acids : metabolic fuels and biosynthetic precursors -- Proteins and enzymes -- Membrane biochemistry and signal transduction -- Nutrition -- Generation of energy from dietary fuels -- Carbohydrate metabolism -- Lipid metabolism -- Nitrogen metabolism -- Integration of metabolism -- Nucleotide synthesis and metabolism -- Organization, synthesis, and repair of DNA -- Gene expression -- DNA technology -- Common laboratory values.…”
View in OPAC
Book -
1703
Role of Neuron-Specific Enolase in the Diagnosis and Disease Monitoring of Sarcoidosis
Published 2022-01-01“…Although angiotensin-converting enzyme (ACE) and soluble interleukin 2 receptor (sIL-2R) are traditionally used for the diagnosis of sarcoidosis, specific diagnostic markers remain to be determined. …”
Get full text
Article -
1704
In Vitro Experimental Assessment of Ethanolic Extract of Moringa oleifera Leaves as an α-Amylase and α-Lipase Inhibitor
Published 2022-01-01“…An explanatory mechanism on how the plant exerts its enzyme inhibitory activities are yet to be detailed. …”
Get full text
Article -
1705
Assessing the diagnostic potential of SATB2 and β-catenin as biomarkers and therapeutic targets in pancreatic ductal adenocarcinoma
Published 2025-01-01“…We evaluated SATB2 expression using immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA). β-catenin was assessed using IHC and real-time polymerase chain reaction (qPCR). …”
Get full text
Article -
1706
Tacrolimus trough level and oxidative stress in Tunisian kidney transplanted patients
Published 2024-12-01“…TAC whole-blood concentrations were measured by the microparticle enzyme immunoassay method and adjusted according to the target range. …”
Get full text
Article -
1707
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes
Published 2024-03-01“…Missense mutations in the catalytic domain cause hyper-autocleavage and are associated with genetic disorders with developmental defects. Despite the enzyme’s biological significance, the molecular architecture of the FAM111A serine protease domain (SPD) is unknown. …”
Get full text
Article -
1708
Optimization of Protease and Amylase Production by Rhizopus oryzae Cultivated on Bread Waste Using Solid-State Fermentation
Published 2019-01-01“…This research was carried for the coproduction of two industrial enzymes: α-amylase and protease via SSF by Rhizopus oryzae on humidified bread waste. …”
Get full text
Article -
1709
De novo biosynthesis of quercetin in Yarrowia Lipolytica through systematic metabolic engineering for enhanced yield
Published 2025-01-01“…We designed a kaempferol biosynthetic pathway by integrating multiple-copy fusion enzyme expression modules, F3H-(GGGGS)2-FLS, into the genome with an optimized linker (GGGGS)2 to enhance kaempferol production from naringenin. …”
Get full text
Article -
1710
Effect of Diets Supplemented With Yeast, Chitin, and Chitosan on the Growth, Immune, and Antioxidant Responses of the Freshwater Prawn Cryphiops (Cryphiops) caementarius
Published 2024-01-01“…However, activated yeast is not effective in increasing the activity of antioxidant enzymes SOD and GST. Therefore, the activated yeast diet can be useful to improve the aquaculture production of C. …”
Get full text
Article -
1711
Increased B Cell-Activating Factor Expression Is Associated with Postoperative Recurrence of Chronic Rhinosinusitis with Nasal Polyps
Published 2022-01-01“…The circulating and tissue BAFF expressions were detected by enzyme-linked immunosorbent assay reverse transcription-polymerase chain reaction and immunohistochemistry. …”
Get full text
Article -
1712
Electrochemical Glucose Sensor Based on Dual Redox Mediators
Published 2024-12-01“…The synergistic effect of PD and Ru(III) was utilized to efficiently facilitate the electron transfer between the enzyme-active center and the electrode. Then, a commercial disposable electrochemical glucose sensor was constructed based on screen-printing electrodes. …”
Get full text
Article -
1713
Interaction mechanism of egg white- derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptor
Published 2020-03-01“…The egg white-derived hexapeptide TNGIIR inhibits angiotensin-converting enzyme (ACE) activity in vitro. In this work, molecular docking revealed that TNGIIR established hydrogen bonds with the S1 (Ala 354), S2 (Gln 281, His 513, Tyr 520 and Lys 511) and S1′ (Glu 162) pockets of ACE. …”
Get full text
Article -
1714
Bioactive molecules from soybeans (Glycine max) with anti-type 2 diabetes activity: a systematic review
Published 2024-03-01“…A search was also conducted on all the key enzymes and bioactive molecules mentioned in the review. …”
Get full text
Article -
1715
Association of Chronic Toxoplasma gondii Infection with Pro-Inflamatory Cytokine Interleukin (IL)-12 Responses in Type-2 Diabetes Mellitus Patients of Bangladesh
Published 2023-01-01“…For this, 100 (N=100) patients with T2DM and 100 (N=100) healthy controls were enrolled to determine the seroprevalence of toxoplasmosis using enzyme-linked immunosorbent assay (ELISA). In addition, ELISA was also performed to determine the level of pro-inflammatory cytokine, interleukin (IL)-12, to understand its role in the development of toxoplasmosis. …”
Get full text
Article -
1716
Gold nanorod-based engineered nanogels for cascade-amplifying photothermo-enzymatic synergistic therapy
Published 2024-12-01“…This ultimately promoted the efficient enzyme-catalyzed reaction of loaded CPO combined with the rich endogenous H2O2 in tumor cells to significantly elevate intracellular ROS levels above the threshold for improved therapeutic outcomes. …”
Get full text
Article -
1717
Changes in wheat protein digestibility and allergenicity: Role of Pediococcus acidilactici XZ31 and yeast during dough fermentation
Published 2023-11-01“…Protein digestibility were evaluated using the sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis and enzyme-linked immunosorbent assay. The effect of protein on intestinal permeability was investigated by Caco-2 cell monolayers. …”
Get full text
Article -
1718
Epidemiological Survey of Toxoplasmosis among Aborted Women in Garmian district, Kurdistan Region, Iraq
Published 2018-07-01“…The main aim of this study is to determine prevalence of toxoplasmosis among aborted women in Garmian region by using both Latex Agglutination Test (LAT) and Enzyme Linked Immunosorbent Assay (ELISA). The study was carried out in Kalar General Hospital to detect Toxoplasma antibodies among 350 samples, in which 250 samples were from aborted women and 100 samples were from normal birth women as a control. …”
Get full text
Article -
1719
Decreased Breg/Th17 Ratio Improved the Prognosis of Patients with Ulcerative Colitis
Published 2018-01-01“…Real-time fluorescent quantitative polymerase chain reaction and immunohistochemistry were applied to determine the expression of Breg cells-related cytokines IL-10 and Th17 cell transcription factor RORγT. Enzyme-linked immunosorbent assay was employed to detect serum IL-10 and IL-17 levels. …”
Get full text
Article -
1720
Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi
Published 2025-06-01“…To address this, ligand-based pharmacophore modeling was used to identify potential inhibitors of the S. typhi LpxH protein, a crucial enzyme in the lipid A biosynthesis pathway. A natural compound library of 852,445 molecules was screened against a pharmacophore model developed from known LpxH inhibitors. …”
Get full text
Article