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1521
Role of Cox-2 in Vascular Inflammation: An Experimental Model of Metabolic Syndrome
Published 2013-01-01“…The objective of this work was to demonstrate the role of COX-2 enzyme at the vascular in experimental model of metabolic syndrome. …”
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1522
Efficient reduction of β-lactoglobulin allergenicity in milk using Clostridium tyrobutyricum Z816
Published 2023-05-01“…Finally, the concentration and digestibility of β-LG in actual samples was quantified using enzyme-linked immunosorbent assay (ELISA) and gastrointestinal digestion simulation experiments. …”
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1523
In vitro efficacy of plant growth-promoting rhizobacteria isolated from ginger (Zingiber officinale) rhizosphere for biological control of plant pathogens
Published 2024-12-01“…Among them, isolate 235A2 demonstrated the highest potential as a biological control agent, with capabilities including phosphate solubilization, nitrogen fixation, protease enzyme production, and significant inhibition rates of F. oxysporum (13.79%), Colletotrichum sp. (55.56%), and Alternaria sp. (35.61%) in vitro. …”
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1524
The Impact of Daily Light Integral from Artificial Lighting on Tomato Seedling Cultivation in Plant Factory
Published 2024-12-01“…The optimal DLI enhanced seedling growth, biomass, root vitality, antioxidant enzyme activity, and photosynthetic pigment synthesis. …”
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1525
Metabolic and hematological disruptions induced by Diphenyl Diselenide in male wistar rats
Published 2024-12-01“…Diphenyldiselenide (DPDS), a potent antioxidant and enzyme inhibitor, exerts cellular toxicity mainly through interaction with thiol group of proteins. …”
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1526
Unraveling relationship between the genetic polymorphism CYP2A13 and nicotine metabolism of male smokers in Medan, Indonesia
Published 2025-02-01“…Abstract Background Nicotine metabolism significantly influences the levels of harmful nicotine metabolites in smokers. CYP2A13, a key enzyme in nicotine and xenobiotic metabolism, is implicated in tobacco smoke-related lung cancer. …”
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1527
Selective mPGES-1 Inhibitor Ameliorated Adjuvant-Induced Arthritis in the Rat Model
Published 2024-01-01“…Both inducible COX-2 (cyclooxygenase-2) and mPGES-1 (microsomal prostaglandin E2 synthase-1) enzymes are responsible for the inflammatory overexpressed PGE2 production. …”
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1528
Ultrasound-assisted extraction of peanut shell by-product: Chemical properties, antioxidant, and anti-inflammatory effects
Published 2024-01-01“…The anti-inflammatory effects of UPE were assessed using the nitric oxide (NO) Griess assay, prostaglandin E2 (PGE2), and interleukin-6 (IL-6) enzyme-linked immunosorbent assay (ELISA). Western blot analysis and reverse transcription polymerase chain reaction (RT-PCR) were used to evaluate the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). …”
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1529
Green chemistry approaches in the analytical validation of fosravuconazole using UV spectrophotometry and HPLC
Published 2025-03-01“…Its mild inhibition of the cytochrome P450 enzyme, which plays a role in adverse effects during polypharmacy, allows for the safe use of fosravuconazole alongside other medications, making it suitable for elderly patients. …”
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1530
Supplementation with serine-enriched non-essential amino acids from minimum essential medium promotes blastocyst development of in vitro-fertilized bovine embryos
Published 2024-12-01“…Analysis of endogenous serine synthases gene expression in oocytes and embryos revealed that phosphoglycerate dehydrogenase, the rate-limiting enzyme in the serine synthesis pathway, is expressed at the morula stage and beyond. …”
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1531
Structural and Functional Annotation of Hypothetical Proteins of O139
Published 2015-06-01“…The analysis revealed that these proteins might have antibiotic resistance activity, DNA breaking-rejoining activity, integrase enzyme activity, restriction endonuclease, etc. Structural prediction of these proteins and detection of binding sites from this study would indicate a potential target aiding docking studies for therapeutic designing against cholera.…”
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1532
Etanercept Attenuates Traumatic Brain Injury in Rats by Reducing Brain TNF-α Contents and by Stimulating Newly Formed Neurogenesis
Published 2013-01-01“…The numbers of the colocalizations of 5-bromodeoxyuridine and doublecortin specific markers in the contused brain injury that occurred during TBI were counted by immunofluorescence staining. Enzyme immunoassay for quantitative determination of TNF-α or etanercept in brain tissues is also performed. …”
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1533
Rhein Inhibits NF-κB Signaling Pathway to Alleviate Inflammatory Response and Oxidative Stress of Rats with Chronic Glomerulonephritis
Published 2022-01-01“…The level of TNF-α, IL-1β, IL-6, and ICAM-1 in rat kidney tissues was determined by enzyme-linked immunosorbent assay (ELISA). Western blot was applied to check the expression of NF-κB in the nucleus and cytoplasm as well as the expression of IκBα and p-IκBα in rat kidney tissues. …”
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1534
A Liquid Chromatography-Tandem Mass Spectrometry Method for Evaluation of Two Brands of Enalapril 20 mg Tablets in Healthy Human Volunteers
Published 2017-01-01“…Enalapril is an angiotensin-converting enzyme inhibitor used for treatment of hypertension and chronic heart disease. …”
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1535
Ternary metal oxide of CuNiCo2O4nanorods (1D) distributed on g-C3N4 (2D) nanocomposite for non-enzymatic glucose sensing application
Published 2025-02-01“…Non-enzymatic glucose sensing has a major demand in research community for developing a good glucose sensor. Because enzyme based glucose sensor has several disadvantages such as high cost, difficult fabrication process and instability. …”
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1536
Plasma Adiponectin and Its Correlation with Carotid Intima-Media Thickness in Obesity and in Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
Published 2023-01-01“…Plasma adiponectin was measured using ELISA (enzyme-linked immunosorbent assay) technique. Ultrasonography was used to diagnose NAFLD. …”
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1537
Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascu...
Published 2016-01-01“…This discrepancy was found to be due to the expression of insulin degrading enzyme. These results suggest that the prevascularized bioartificial pancreas is potentially a tool for improving long-term islet cell survival in vivo.…”
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1538
Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum
Published 2025-02-01“…Then, a combined approach of qRT-PCR, enzyme assay, and ultrastructure observation was applied to investigate its regulatory effects on the related genes, cellular parameters, and histological structures, respectively. …”
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1539
Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis
Published 2015-01-01“…BP was controlled with angiotensin-converting-enzyme inhibitors and headache improved. In a new MRI a month later improvement of white matter lesions was observed. …”
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1540
Novel mitochondrial-targeted alkyl chains act as fungal specific inhibitors of C. neoformans
Published 2025-02-01“…For example, C. neoformans possesses an Alternative Oxidase enzyme (Aox) that has been implicated in stress resistance and virulence that may represent a viable antifungal target. …”
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