Purification of Peroxidase from Rice Bran Using Expanded-Bed Ion-Exchange Chromatography by G.V. Gautério, S.S. Fernandes, F.O. Molon, F.S. Figueira, J.G. Buffon, S.J. Kalil

“…Among the various techniques used for the purification of enzymes, expanded-bed adsorption chromatography is particularly popular because it offers several advantages, such as greater interactions between adsorbents and target molecules, increased overall yield, potential for a scale-up and shorter process times. …”
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Determination of the incidence of embryonic death by means of real-time ultrasound scanning in ewes by M. Kemal SARIBAY, Hüseyin ERDEM

“…Blood samples were collected simultaenously with ultrasonography and measurements of plasma progesterone with enzyme immunoassay (EIA). Of 73 ewes, 60 ewes were pregnant and 79 embryos were detected and embryonic mortality rate was 8.9 % (7 of 79 embriyos) on day 18. …”
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Epigenetic Regulations in Neural Stem Cells and Neurological Diseases by Hang Zhou, Bin Wang, Hao Sun, Xingshun Xu, Yongxiang Wang

“…At the same time, Ten-eleven translocation (Tet) methylcytosine dioxygenases, the rate-limiting enzyme for the 5-hydroxymethylation reaction from 5-methylcytosine to 5-hydroxymethylcytosine, play a critical role in the tumorigenesis and the proliferation and differentiation of stem cells. …”
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QSAR modelling and docking analysis of some thiazole analogues as alfa-glucosidase inhibitors by Muhammad Tukur Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba

“…-glucosidase inhibitors having improved potency toward the target enzyme. …”
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Biological Properties and Clinical Significance of Lipoprotein-Associated Phospholipase A2 in Ischemic Stroke by Shuang Zhang, Shuchun Huang, Dingju Hu, Fenglong Jiang, Yanli Lv, Guoqi Liu

“…One of these is lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that can hydrolyze circulating oxidized phospholipids, generating proinflammatory lysophosphatidylcholine and promoting the development of atherosclerosis. …”
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Diagnosis of GM-1 gangliodosis in Cuba by Caridad Menéndez Saínz, Sergio González García, Claudina Zaldívar Muñoz, Alina González-Quevedo Monteagudo

“…<strong>Background:</strong> GM-1 gangliosidosis is included in the group of lysosomal diseases and is characterized by a deficiency of the enzyme b-galactosidase, which as a consequence produces accumulation of GM1 ganglioside in nervous cells and galactosil oligosaccharides and products of keratan sulfate degradation in other tissues. …”
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The Current Status and Advance in Treatment of Glycogen Storage Disease Type Ⅰb by JIANG Jingjing, MA Mingsheng

“…Glycogen storage diseases (GSDs)refer to a group of metabolic disorders caused by congenital enzyme deficiencies. This group of diseases are characterized by abnormal glycogen metabolism. …”
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Machine learning based QSAR and Molecular Dynamics simulations in the structural design and mechanism of action of imidazole derivatives with anti-melanoma activity by Rosalvo Ferreira de Oliveira Neto, Sérgio Ruschi Bergamachi Silva, Cintia Emi Yanaguibashi Leal, Edilson Beserra de Alencar Filho

“…Additionally, the imidazopyrazine nucleus was compared to a known inhibitor of the Aurora Kinase enzyme, an important target in cancer therapy. Thus, strategic imidazopyrazines were subjected to comparative molecular dynamics calculations, providing inferences about their possible mechanisms of action. …”
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Current Concepts of Hyperinflammation in Chronic Granulomatous Disease by Nikolaus Rieber, Andreas Hector, Taco Kuijpers, Dirk Roos, Dominik Hartl

“…The underlying pathomechanisms driving hyperinflammatory reactions in CGD are poorly understood, but recent studies implicate reduced neutrophil apoptosis and efferocytosis, dysbalanced innate immune receptors, altered T-cell surface redox levels, induction of Th17 cells, the enzyme indolamine-2,3-dioxygenase (IDO), impaired Nrf2 activity, and inflammasome activation. …”
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The Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic Fibroblasts by Ajith Vengellur, Elizabeth Grier, John J. LaPres

“…Increased cell death in the HIF1α −/− cells was correlated with lower metallothionein protein, elevated levels of reactive oxygen species, and decreased superoxide dismutase enzyme activity. The total and oxidized glutathione levels, and, correspondingly, lipid peroxidation levels were elevated in the null cells compared to wild-type cells, indicating increased antioxidant demand and greater oxidative stress. …”
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Effects of Tannin Extract from Gongronema latifolium Leaves on Lipoxygenase Cucumeropsis manii Seeds by Sabinus O. O. Eze, Bennett C. Nwanguma

“…This tannin extract could be included during food processing as preservative against food deterioration that might be caused by oxidative enzymes such as lipoxygenase.…”
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Effects of Glucomannan on the Sacculus Rotundus and Peripheral Blood Lymphocytes in New Zealand Rabbits during Aflatoxicosis by Emrah Sur, Hasan Hüseyin Dönmez, Murat Boydak, Mehmet Bozkurt Ataman

“…This study was aimed to determine the effects of the glucomannan added to aflatoxin- (AF-) contaminated diet on the sacculus rotundus and peripheral blood lymphocytes of New Zealand rabbits by histological and enzyme histochemical methods. Twenty-four adult rabbits of both sexes were divided into four equal groups, namely, as control, glucomannan 0.2 g/day, AF 125 μg/kg/day, and glucomannan combined with AF. …”
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Tinctoride A, a New Hopan-Type Triterpenoic Peracid from the Thallus of Lichen Parmotrema Tinctorum (Despr. ex Nyl.) Hale by Le-Thuy-Thuy-Trang Hoang, Thanh-Nha Tran, Thi-Phi-Giao Vo, Hoang-Vinh-Truong Phan, Phan-Si-Nguyen Dong, Dinh-Tri Mai, Ngoc-An Nguyen, Thi-Minh-Suong Huynh, Hong Truong Luu, Tien-Dung Le, Minh-Trung Dao, Van-Kieu Nguyen

“…Their chemical structures were identified by extensive 1D and 2D NMR analysis and high-resolution mass spectroscopy and compared with those reported in the literature. The enzyme inhibitory potential of compounds 1–3 against α-glucosidase was investigated, exhibiting nil to weak inhibitory activity.…”
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Detection of Antibody against Helicobacter pylori in the Saliva of Patients with Dyspepsia by Robert L Clancy, Allan W Cripps, Diana C Taylor, Lois A McShane, Victor J Webster

“…This study examined the clinical value of a saliva enzyme-linked immunoadsorbent assay (ELISA) for anti-H pylori antibody, compared with the serum ELISA assay, and found the sensitivity of the saliva assay was 89%, specificity 94%, accuracy 93%, positive predictive value 89% and negative predictive value 94%. …”
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The Protective Potential Role of ACE2 against COVID-19 by Fereshteh Golab, Gelareh Vahabzadeh, Leila SadeghRoudbari, Arefeh Shirazi, Robabeh Shabani, Sara Tanbakooei, Lida Kooshesh

“…The angiotensin-converting enzyme 2 (ACE2) has been shown as a necessary receptor to cell fusion, which is involved in infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). …”
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Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reacti... by Nikolaus Berndt, Sascha Bulik, Hermann-Georg Holzhütter

“…By contrast, progressive inhibition of the enzyme aconitase had only little impact on these mitochondrial parameters. …”
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Variation in Macro and Trace Elements in Progression of Type 2 Diabetes by Khalid Siddiqui, Nahla Bawazeer, Salini Scaria Joy

“…Trace elements participate in tissue and cellular and subcellular functions; these include immune regulation by humoral and cellular mechanisms, nerve conduction, muscle contractions, membrane potential regulations, and mitochondrial activity and enzyme reactions. The status of micronutrients such as iron and vanadium is higher in type 2 diabetes. …”
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Reduction of Phosphorus Pollution from Broilers Waste through Supplementation of Wheat Based Broilers Feed with Phytase by Ahmed Abdel-Megeed, Arifa Tahir

“…The present study was conducted to reduce phosphorus pollution from broilers waste by supplementing phytase enzyme in broilers fee. Two hundred two-week-old broilers (Hubbard) were selected and randomly allocated to three dietary treatment groups, one control group (without phytase) and two trial groups (group A with 300 U/kg phytase and group B with 600 U/kg phytase). …”
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Towards a Quantitative Description of Proteolysis: Contribution of Demasking and Hydrolysis Steps to Proteolysis Kinetics of Milk Proteins by Mikhail M. Vorob’ev

“…Kinetic studies of the proteolysis of β-casein and β-lactoglobulin by various proteolytic enzymes throughout the whole degree of hydrolysis are reviewed. …”
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Identification and Mechanism of Echinochloa crus-galli Resistance to Fenoxaprop-p-ethyl with respect to Physiological and Anatomical Differences by Amany Hamza, Aly Derbalah, Mohamed El-Nady

“…The resistance of E. crus-galli to fenoxaprop-p-ethyl may be due to the faster metabolism of fenoxaprop-p-ethyl below the physiologically active concentration or the insensitivity of its target enzyme (Acetyl-CoA carboxylase).…”
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