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1461
Association of Toll-Like Receptor 2 (TLR2) Expression in Placenta and Intrauterine Exposure to Hepatitis B Virus
Published 2022-01-01“…Methods. We performed enzyme-linked immunoadsorbent assay of HBeAg, HBsAg titer, Anti-HBs, and Anti-HBc to 59 HBsAg-positive pregnant women and identified HBV DNA using nested PCR in their cord blood during delivery for evidence of exposure to HBV DNA. …”
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1462
The Decreased Treg Cells Number Associated with Retinal Lesion Size in Ocular Toxoplasmosis
Published 2024-01-01“…Isolation of peripheral blood mononuclear cells (PBMC) was performed to measure the number of Treg cells using flow cytometry and interleukin-27 levels were assessed using the Sandwich enzyme-linked immunosorbent assay (ELISA) technique. …”
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1463
Mediators of intercellular interactions and histological signs of chronic viral liver disease
Published 2014-11-01“…Scores of ICAM-1, VCAM-1, Е-selectin, L-selectin and the Р-selectin were determined by enzyme-linked immunoassay method and were compared to values of Knodell histological activity index and Desmet fibrosis score as well as to E.M. …”
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1464
Plasma Levels of Tumor Necrosis Factor-Alpha and Interleukin-6 in Obsessive Compulsive Disorder
Published 2007-01-01“…TNF-α and IL-6 concentrations in blood were determined by enzyme-linked immunosorbent assay (ELISA). Results. …”
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1465
Interleukins Affect Equine Endometrial Cell Function: Modulatory Action of Ovarian Steroids
Published 2014-01-01“…Prostaglandins concentration was determined using the direct enzyme immunoassay (EIA) method. Our findings reveal a functional linking between ovarian steroids and IL-stimulated PG secretion by equine endometrial cells. …”
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1466
Impact of Power Ultrasound on Antihypertensive Activity, Functional Properties, and Thermal Stability of Rapeseed Protein Hydrolysates
Published 2017-01-01“…The effects of power ultrasound pretreatments on the degree of hydrolysis (DH), angiotensin-I-converting enzyme (ACE) inhibitory activity, amino acid composition, surface hydrophobicity, protein solubility, and thermal stability of ACE inhibition of rapeseed protein hydrolysates were evaluated. …”
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1467
Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Dise...
Published 2017-01-01“…To investigate the possible effects of APN in the pathogenesis of HFRS, total and high molecular weight (HMW) APN levels in the plasma of patients with HFRS were quantified using enzyme-linked immunosorbent assay (ELISA). Compared with those in healthy controls, the plasma total and HMW APN levels in patients were elevated to different degrees from the fever onset and remained high at the convalescent phase. …”
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1468
Role of cytokines and nitric oxide in the induction of tuberculostatic macrophage functions
Published 2000-01-01“…Tumour necrosis factor (TNF) activity was assayed by measuring its cytotoxic activity on L-929 cells, interleukin-6 (IL-6) and interferon γ (IFN-γ) were assayed by enzyme-linked immunosorbent assay (ELISA), whereas NO levels were detected by Griess colorimetric reactions in the culture supernatant of macrophages incubated with IFN-γ , TNF or NO and subsequently exposed to either BCG-I or BCG-S. …”
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1469
Inhibitory Potential of Five Traditionally Used Native Antidiabetic Medicinal Plants on α-Amylase, α-Glucosidase, Glucose Entrapment, and Amylolysis Kinetics In Vitro
Published 2014-01-01“…EL, EO, AM, and SL extracts (5000 μg/mL) were found to significantly (P<0.05) inhibit α-glucosidase (between 87.41±3.31 and 96.87±1.37% inhibition). Enzyme kinetic studies showed an uncompetitive and mixed type of inhibition. …”
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1470
Freeze-Drying Microencapsulation of <i>Ruellia tuberosa</i> L. Extracts: A Comparative Study Using Different Polymers as Encapsulants
Published 2025-01-01“…Alpha-amylase inhibition tests showed that microcapsules effectively inhibit the enzyme, with the coating combination performing best, followed by gum Arabic and then maltodextrin. …”
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1471
Safety and Tolerability of Initiating Maximum-Dose Sacubitril-Valsartan in Patients on Target Dose Renin-Angiotensin System Inhibitors
Published 2019-01-01“…Guidelines recommend initiating half-dose sacubitril-valsartan before up-titration even to patients already on target dose angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARB). …”
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1472
In Silico Screening, Synthesis and In Vitro Evaluation of Some Quinazolinone and Pyridine Derivatives as Dihydrofolate Reductase Inhibitors for Anticancer Activity
Published 2009-01-01“…Dihydrofolate reductase (DHFR) is the important target for anticancer drugs belonging to the class of antimetabolites as the enzyme plays important role in the de novo purine synthesis. …”
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1473
Hypobaric Hypoxia Imbalances Mitochondrial Dynamics in Rat Brain Hippocampus
Published 2015-01-01“…Mitochondrial morphology, distribution within neurons, enzyme activity of respiratory complexes, Δψm, ADP: ATP, and expression of fission/fusion key proteins were determined. …”
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1474
Allergic Contact Dermatitis Is Associated with Significant Oxidative Stress
Published 2014-01-01“…In 40 patients, interleukin- (IL-) 6, monocyte chemoattractant protein (MCP-1), and IL-10 levels were measured in sera with the Evidence Investigator Cytokine & Growth factors High-Sensitivity Array, total peroxide concentration (TPX) and total antioxidant capacity (TAC) by means of spectrophotometry, and the plasma concentrations of adiponectin and leptin by the quantitative sandwich enzyme immunoassay technique. Results. TNF-α level (P < 0.01) and TPX (P < 0.0001) were increased whilst IL-10 (P < 0.05) and TAC (P < 0.0001) were decreased in the patients as compared to controls. …”
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1475
The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome
Published 2013-01-01“…The levels of antioxidant enzymes were significantly lower in the MS group than in the non-MS group. …”
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1476
Simvastatin Does Not Affect Vitamin D Status, but Low Vitamin D Levels Are Associated with Dyslipidemia: Results from a Randomised, Controlled Trial
Published 2010-01-01“…Statin drugs act as inhibitors of the 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase enzyme early in the mevalonate pathway, thereby reducing the endogenous cholesterol synthesis. …”
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1477
Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases
Published 2013-01-01“…Indoleamine 2,3-dioxygenase 1 (IDO1), the L-tryptophan-degrading enzyme, plays a key role in the immunomodulatory effects on several types of immune cells. …”
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1478
The Expression of miR-192 and Its Significance in Diabetic Nephropathy Patients with Different Urine Albumin Creatinine Ratio
Published 2016-01-01“…The serum miR-192 levels were detected by Real-Time PCR and transforming growth factor-β1 (TGF-β1) and fibronectin (FN) were detected by enzyme-linked immunosorbent assay. The relationships among these parameters were analyzed by Pearson correlation analysis and multiple linear regression analysis. …”
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1479
The Difference in Interleukin-19 Serum on Degrees of Acne Vulgaris Severity
Published 2018-01-01“…Sample subjects were patients with acne vulgaris who met the inclusion criteria. Enzyme-linked immunosorbent assay (ELISA) study was applied to measure IL-19 serum. …”
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1480
Humoral Autoimmune Responses to Insulin-Like Growth Factor II mRNA-Binding Proteins IMP1 and p62/IMP2 in Ovarian Cancer
Published 2014-01-01“…In this study, autoantibody responses to two members (IMP1 and p62/IMP2) of IMPs were evaluated by enzyme-linked immunosorbent assay (ELISA), western blotting, and indirect immunofluorescence assay in sera from patients with ovarian cancer and normal human individuals. …”
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