SHOX Duplication and Tall Stature in a Patient with Xq Deletion and Vascular Disease by J. M. Ramirez, F. A. Rodríguez, M. I. Echeverría, A. L. Vargas, A. E. Calderón, R. M. Miatello, N. F. Renna

“…Also, taking into account the fact that the gene locus of the angiotensin-converting enzyme type 2 (ACE2) is located in Xp, our goal was to investigate the influence of this gene in the development of cardiovascular disease. …”
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A Case of Reverse Takotsubo Cardiomyopathy Incited by a Spinal Subdural Hematoma by Kyle Sanchez, Steven Glener, Nathan E. Esplin, Okorie N. Okorie, Amay Parikh

“…It mimics myocardial infarction clinically and includes elevated cardiac enzymes, but echocardiography reveals apical ballooning and basal hyperkinesis. …”
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AI-driven prediction of drug activity against Toxoplasma gondii: Data augmentation and deep neural networks for limited datasets by Natalia V. Karimova, Ravithree D. Senanayake

“…Toxoplasmosis, caused by Toxoplasma gondii (T. gondii), is a serious global health concern, particularly in immunocompromised individuals. Inhibiting the enzyme TgDHFR is a promising strategy for developing treatments. …”
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Superoxide Dismutase 3 Limits Collagen-Induced Arthritis in the Absence of Phagocyte Oxidative Burst by Tiina Kelkka, Juha Petteri Laurila, Outi Sareila, Peter Olofsson, Mikko Olavi Laukkanen, Rikard Holmdahl

“…Extracellular superoxide dismutase (SOD3), an enzyme mediating dismutation of superoxide into hydrogen peroxide, has been shown to reduce inflammation by inhibiting macrophage migration into injured tissues. …”
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The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection by GI Perez-Perez, T Marrie, H Inouye, T Shimoyama, G Marshall, G Meiklejohn, MJ Blaser

“…Serological studies in developed and developing countries using enzyme-linked immunosorbent assays have validated this technique as a rapid, noninvasive method for the diagnosis of Helicobacter pylori infections. …”
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Phytochemical Analysis and Antioxidant and Antidiabetic Activities of Extracts from Bergenia ciliata, Mimosa pudica, and Phyllanthus emblica by Basanta Kumar Sapkota, Karan Khadayat, Kabita Sharma, Bimal Kumar Raut, Dipa Aryal, Bijaya Bahadur Thapa, Niranjan Parajuli

“…Diabetes is a metabolic disorder of high blood sugar levels which leads to various chronic health-related complications. The digestive enzymes α-amylase and α-glucosidase play a major role in the hydrolysis of starch to glucose; hence, inhibiting these enzymes is considered an important strategy for the treatment of diabetes. …”
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From the Role of Microbiota in Gut-Lung Axis to SARS-CoV-2 Pathogenesis by Sara Ahmadi Badi, Samira Tarashi, Abolfazl Fateh, Pejman Rohani, Andrea Masotti, Seyed Davar Siadat

“…Additionally, the gut microbiota composition affects (and is affected by) the expression of angiotensin-converting enzyme-2 (ACE2), which is the main receptor for SARS-CoV-2 and contributes to regulate inflammation. …”
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Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors by Zhi-Lan Ye, Yuan Cao

“…Conclusions: Trigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme complexes, and modulating apoptotic and neurotrophic factors. …”
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Morphological and Molecular Characteristics of Endophytic Fungi in Sugarcane as Antagonists of the Pathogen Fusarium sacchari by Asniah Asniah, Muhammad Taufik

“…Inhibition tests were conducted through dual culture and volatile compound testing, as well as enzyme production. The research results obtained 38 endophytic fungal isolates from sugarcane plants that have the ability to inhibit the pathogen F. sacchari. …”
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Serum salusin levels in diarrhea- and constipation-predominant irritable bowel syndrome by Elif Tugba Tuncel, Seda Sabah Ozcan, Mehmet Korkmaz, Elif Börekci

“…Methodology The study participants included 28 diagnosed with constipation-predominant IBS, 29 (34.1%) diagnosed with diarrhea-predominant IBS (D-IBS), and 28 (32.9%) controls. Enzyme-linked immune-sorbent assay (ELISA) method has been used for the measurement of salusin levels. …”
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Amphetamine Positive Urine Toxicology Screen Secondary to Atomoxetine by Joshua L. Fenderson, Amy N. Stratton, Jennifer S. Domingo, Gerald O. Matthews, Christopher D. Tan

“…On arrival to the hospital, a urine toxicological drug screen with immunochemical cloned enzyme donor immunoassay (CEDIA) was performed. Results were positive for amphetamines; however, the presence of these substances could not be confirmed with urine gas chromatography-mass spectrometry (GC-MS). …”
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Conformational and Functional Properties of Soybean Proteins Produced by Extrusion-Hydrolysis Approach by Wenjun Ma, Baokun Qi, Rokayya Sami, Lianzhou Jiang, Yang Li, Hui Wang

“…The hydrolysis degrees, molecular weight profiles, solubilities, surface hydrophobicities, sulphydryl contents, disulfide bound, water holding capacity, emulsion, and foam properties of the protein isolated from the enzyme-hydrolyzed extruded soybeans were analyzed. …”
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Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model by Jiqing Xu, Fred de Winter, Catherine Farrokhi, Edward Rockenstein, Michael Mante, Anthony Adame, Jonathan Cook, Xin Jin, Eliezer Masliah, Kuo-Fen Lee

“…Furthermore, we showed that soluble ectodomains of both type I and type III NRG1 significantly increased expression of Aβ-degrading enzyme neprilysin (NEP) in primary neuronal cultures. …”
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Porphyromonas gulae and canine periodontal disease: Current understanding and future directions by Kyu Hwan Kwack, Eun-Young Jang, Cheul Kim, Young-Suk Choi, Jae-Hyung Lee, Ji-Hoi Moon

“…This review examines the initial isolation, phylogenetic analysis, habitat, host range, relationships with host health status and age, and key pathogenic determinants, including fimbriae, proteases, citrullinating enzyme, and lipopolysaccharide. Control strategies discussed include polyphosphate to disrupt haeme/iron utilization, clindamycin with interferon alpha to reduce bacterial load and enhance the immune response, and a protease inhibitor. …”
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Monovalent Lectin Microvirin Utilizes Hydropathic Recognition of HIV-1 Env for Inhibition of Virus Cell Infection by Bibek Parajuli, Kriti Acharya, Harry Charles Bach, Shiyu Zhang, Cameron F. Abrams, Irwin Chaiken

“…MVN binding site amino acid residues were individually replaced by alanine, and the resulting purified recombinant MVN variants were examined for gp120 interaction using competition Enzyme-Linked Immunosorbent Assay (ELISA), biosensor surface plasmon resonance, calorimetry, and virus neutralization assays. …”
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach by Damini Sood, Neeraj Kumar, Aarushi Singh, Meena Kishore Sakharkar, Vartika Tomar, Ramesh Chandra

“…We found that among all four FQ molecules, ofloxacin showed the highest antibacterial activity through in silico assays with a strong interaction (−38.52 kJ/mol) with the antibacterial target protein (topoisomerase-II DNA gyrase enzyme). The pharmacological and pharmacokinetic analysis also showed that the compounds ciprofloxacin, ofloxacin, lomefloxacin and norfloxacin have good pharmacological properties. …”
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Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450 by Benković Goran, Bojić Mirza, Maleš Željan, Tomić Siniša

“…The objective of this study was to screen the metabolism of 30 selected flavonoid aglycons mediated by the most relevant metabolic enzymes, human liver cytochromes P450. For this purpose, in vitro experiments with human liver microsomes and recombinant enzymes were conducted. …”
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Population pharmacokinetics of ramipril in patients with chronic heart failure: A real-world longitudinal study by Trobec Katja Čvan, Grabnar Iztok, Trontelj Jurij, Lainščak Mitja, Kos Mojca Kerec

“…In patients with chronic heart failure (CHF), the use of angiotensin-converting enzyme inhibitors, including ramipril, is recommended to reduce the risk of heart failure worsening, hospitalisation, and death. …”
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A climatically significant abiotic mechanism driving carbon loss and nitrogen limitation in peat bogs by Alexandra B. Cory, Rachel M. Wilson, M. Elizabeth Holmes, William J. Riley, Yueh-Fen Li, Malak M. Tfaily, Sarah C. Bagby, Isogenie Field Team, EMERGE Project Coordinators, Patrick M. Crill, Jessica G. Ernakovich, Virginia I. Rich, Jeffrey P. Chanton

“…Numerous sterility assessments rule out biological contamination or extracellular enzyme activity as significant sources of this CO2. …”
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Blastomyces dermatitidis Yeast Lysate Antigen Combinations: Antibody Detection in Dogs with Blastomycosis by Alex R. Boyd, Jamie L. VanDyke, Gene M. Scalarone

“…Based on results obtained from a preliminary comparative study, five combinations of these isolates and one individual isolate were tested against 92 serum specimens from dogs with culture-proven or histologically-confirmed blastomycosis, using the indirect enzyme-linked immunosorbent assay (ELISA). Mean absorbance values obtained from the sera ranged from 0.905 with the individual T-58 antigen to 1.760 using an antigen combination (T-58 + T-66 + WI-R). …”
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