Impact of Temozolomide on Immune Response during Malignant Glioma Chemotherapy by Sadhak Sengupta, Jaclyn Marrinan, Caroline Frishman, Prakash Sampath

“…Deletion of O6-methylguanine-DNA-methyltransferase (MGMT) activity, a DNA repair enzyme, by temozolomide has been determined to be the cause of lymphopenia. …”
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A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation by Jyotirmoy Sarker, Pritha Das, Sabarni Sarker, Apurba Kumar Roy, A. Z. M. Ruhul Momen

“…SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, uses the host cell membrane receptor angiotensin-converting enzyme 2 (ACE2) for anchoring its spike protein, and the subsequent membrane fusion process is facilitated by host membrane proteases. …”
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Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. by Xi Li, Guanghua Xiong, Manni Luo, Siwan Mao, Ruiying Zhang, Ziwei Meng, Juan Li, Xinjun Liao

“…On the other hand, the locomotor behavior abilities and the antioxidant enzyme activities such as CAT and SOD were obviously decreased under the DrPGRP-5 KD conditions. …”
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Detection and Validation of A2 Milk Suitable for Consumers Having Milk Intolerance by ELISA Method by Mediha Esra Yayla

“…In this study, the quantitative analysis and validation of β-casein A1 and A2 proteins in cow's milk by EnzymeLinked ImmunoSorbent Analysis (ELISA) method was investigated. …”
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Effect of Transient Nicotine Load Shock on the Performance of Pseudomonas sp. HF-1 Bioaugmented Sequencing Batch Reactors by Dong-sheng Shen, Li-jia Wang, Hong-zhen He, Mei-zhen Wang

“…The results showed that, under 500–2500 mg/L of transient nicotine shocks, all the reactors still could realize 100% of nicotine degradation in 4 days of recovery, while the key nicotine degradation enzyme HSP hydroxylase increased in expression. Though the dramatic increase of activities of ROS, MDA, SOD, and CAT suggested that transient nicotine shock loads could induce oxidative stress on microorganisms in activated sludge, a decrease to control level demonstrated that most of the microorganisms could resist 500–1500 mg/L of transient nicotine shock under the protection from strain HF-1. …”
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Glucoraphanin conversion into sulforaphane and related compounds by gut microbiota by Tetiana R. Dmytriv, Tetiana R. Dmytriv, Oleh Lushchak, Oleh Lushchak, Volodymyr I. Lushchak, Volodymyr I. Lushchak

“…Sulforaphane is formed by the hydrolysis of glucoraphanin by a plant enzyme called myrosinase, which is inactivated in the stomach of mammals. …”
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Underlying anti-hypertensive mechanism of the Mizuhopecten yessoensis derived peptide NCW in spontaneously hypertensive rats via widely targeted kidney metabolomics by Wenjun Xue, Wenzhu Zhao, Sijia Wu, Zhipeng Yu

“…The angiotensin-converting enzyme (ACE) inhibitory peptide NCW derived from Mizuhopecten yessoensis has been demonstrated to have significant in vivo anti-hypertensive effects, however, its anti-hypertensive mechanism is still not fully clarified. …”
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The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury by Damien D. Pearse, Francisco C. Pereira, Katina Chatzipanteli, Francisco W. Dalton Dietrich, Mary Bartlett Bunge

“…Hybridization of the oligonucleotide to the mRNA then interferes with the normal processing of that mRNA at the ribosome or targets the RNA duplex for cleavage by the RNA digestive enzyme, ribonuclease H, resulting in greatly reduced expression of the coded protein. …”
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Probiotics: Comprehensive Exploration of the Growth Promotion Mechanisms in Shrimps by Joanna Xuan Hui Goh, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Kooi-Yeong Khaw, Gokhan Zengin, Kok Gan Chan, Vengadesh Letchumanan, Learn-Han Lee, Bey-Hing Goh

“…Besides, elevated digestive enzyme activities following the introduction of probiotics may help enhance digestibility and utilization. …”
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Protective Effect of Vitamins C and E on Depot-Medroxyprogesterone Acetate-Induced Ovarian Oxidative Stress In Vivo by Atik Ismiyati, I. Wayan Arsana Wiyasa, Dwi Yuni Nur Hidayati

“…Analysis of SOD level was done by enzyme linked immunosorbent assay (ELISA) technically. …”
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Interleukin-15 and Tumor Necrosis Factor-α in Iraqi Patients with Alopecia Areata by Zainab A. Kamil, Galawish A. Abdullah, Haider Hashim Zalzala

“…Serum concentrations of IL-15 and TNF-α assessed using the enzyme-linked immunosorbent assay. Results. The mean serum concentration values for IL-15 and TNF-α were higher significantly in patients with AA than in controls (2.35 versus 0.35 pg/mL and 50.11 versus 20.92 pg/mL, respectively). …”
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Correlation between Serum Osteopontin and miR-181a Levels in Allergic Rhinitis Children by Wenlong Liu, Qingxiang Zeng, Renzhong Luo

“…Serum was collected to examine the level of OPN and Th1/Th2 cytokines by enzyme-linked immunosorbent assay (ELISA) and the level of miR-181a by quantitative polymerase chain reaction (qPCR). …”
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Elevated Aminotransferase Activity as an Indication of Muscular Dystrophy: Case Reports and Review of the Literature by S Zamora, C Adams, JD Butzner, H Machida, Rb Scott

“…Paradoxically, the increase in ALT activity was greater than that of serum aspartate aminotransferase (three to 16 times normal), an enzyme whose elevation is generally recognized as being less specific and indicative of muscle, cardiac, kidney, pancreatic, red blood cell or hepatic injury. …”
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General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles by Yongliang Yang, S. James Adelstein, Amin I. Kassis

“…Previously, we published a literature mining of potential targets for our in-house enzyme-mediated cancer imaging and therapy technology. …”
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Postharvest Analysis of Lowland Transgenic Tomato Fruits Harboring hpRNAi-ACO1 Construct by Bita Behboodian, Zainon Mohd Ali, Ismanizan Ismail, Zamri Zainal

“…Changes in cell wall degrading enzyme activities were also investigated in cases where the transgenic fruits exhibited reduced rates of firmness loss, which can be associated with a decrease in pectin methylesterase (PME) and polygalacturonase (PG) activities. …”
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Subetta Treatment Increases Adiponectin Secretion by Mature Human Adipocytes In Vitro by Jim Nicoll, Evgeniy A. Gorbunov, Sergey A. Tarasov, Oleg I. Epstein

“…Secretion of adiponectin was measured by quantitative enzyme-linked immunosorbent assay (ELISA). Results. …”
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The Role of Angiotensin Antagonism in Coronary Plaque Regression: Insights from the Glagovian Model by Abdul H. Alkatiri, Doni Firman, Amir A. Alkatiri, Paskalis I. Suryajaya, Albert Sudharsono

“…The benefit of antagonizing the effect of the renin angiotensin aldosterone system (RAAS), notably by the use of angiotensin-converting enzyme inhibitor (ACEi) and angiotensin II type 1 receptor blocker (ARB) for coronary artery disease (CAD), has been demonstrated in multiple studies, which may be attributed to their ability to inhibit the deleterious effect of RAAS to the cardiovascular system. …”
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A Case of Histoplasma capsulatum Causing Granulomatous Liver Disease and Addisonian Crisis by P Wong, S Houston, B Power, E Lalor, VG Bain

“…A 56-year-old man with persistently elevated liver enzyme levels, fatigue, lethargy and a 9.0 kg weight loss over six months underwent a percutaneous liver biopsy that demonstrated multiple granulomas. …”
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Anti-Factor H Antibodies in Egyptian Children with Hemolytic Uremic Syndrome by Shereen Shawky, Hesham Safouh, Mona Gamal, Mohammed M. Abbas, Azza Aboul-Enein, Toshihiro Sawai, Yosra Fahmy, Heba Selim

“…All candidates were subjected to an assessment of anti-FH in serum by a homemade enzyme-linked immunosorbent assay technique. Results. …”
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Thymol maintains peppers quality by regulating antioxidant capacity, cell wall metabolism and membrane lipid metabolism by Xue Li, Xiaogang Wang, Jianye Chen, Donglan Luo, Sen Cao, Liangjie Ba

“…Additionally, thymol application inhibited the hydrolysis of pepper cell wall components and decreased the activities of enzymes related to cell wall and membrane lipid metabolism. …”
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