Effects of Tai Chi Training on Antioxidant Capacity in Pre- and Postmenopausal Women by Attakorn Palasuwan, Daroonwan Suksom, Irène Margaritis, Suphan Soogarun, Anne-Sophie Rousseau

“…Besides the well-known effects of TC on balance, flexibility, and maximum leg extensor strength, TC (1) increased erythrocyte glutathione peroxidase activity—an aerobic training-responsive antioxidant enzyme—and plasma total antioxidant status and (2) decreased plasma total homocysteine, a cardiovascular risk marker. …”
Get full text

Antibacterial Effect of Dihydromyricetin on Specific Spoilage Organisms of Hybrid Grouper by Wenbo Huang, Jing Xie

“…Through analyzing cell permeability, enzyme activity, and images of the confocal laser scanning microscope (CLSM), we further studied the antibacterial mechanism of DMY emulsion on specific spoilage bacteria. …”
Get full text

Enzymatic functionalization of bacterial nanocellulose: current approaches and future prospects by Monika Kaczmarek, Aneta Monika Białkowska

“…An alternative to these procedures is the highly specific enzymatic modification of bacterial nanocellulose, which perfectly fits into the assumptions of green technologies, making the process eco-friendly and not limiting any outlooks for further usage of the obtained biocomposites. The employment of enzymes for the targeted alteration of this material’s properties is based on either a direct method, such as controlled hydrolysis and nanofication [i.e., synthesis of different morphological forms of bacterial cellulose (e.g., rod-shaped nanocrystals)] using cellulases, and/or attachment of reactive functional groups into the polymer structure via oxidation (e.g., utilizing a laccase/TEMPO catalytic system or lytic polysaccharide monooxygenases) and esterification catalyzed by lipases; or an indirect procedure involving the application of bacterial nanocellulose as a matrix for enzyme immobilization (e.g., laccase, glucose oxidase, horseradish peroxidase, lysozyme, bromelain, lipase, papain), thus creating a specific catalytic system. …”
Get full text

ACE Inhibitor-Induced Angioedema of the Intestine: Case Report, Incidence, Pathophysiology, Diagnosis and Management by Gavin Oudit, Nigel Girgrah, Johane Allard

“…Angiotensin-converting enzyme (ACE) inhibitor-induced angioedema of the intestine (AIAI) occurs in a minority of patients taking an ACE inhibitor. …”
Get full text

Canadian Hepatitis C Look-Back Investigation to Detect Transmission from an Infected General Surgeon by Meenakshi Dawar, Tammy L Stuart, Lamont E Sweet, Anne M Neatby, Lewis P Abbott, Anton P Andonov, Tom Wong, Robert Gervais, Rob Stirling

“…The surgeon’s infection onset date could not be determined; however, episodic hepatic enzyme elevations were first detected in November 2004 and again in February 2007. …”
Get full text

BIOINFORMATIC ANALYSIS OF THE GENOME OF THE Geobacillus stearothermophilus 22 STRAIN ISOLATED FROM THE GARGA HOT SPRING, BAIKAL REGION by A. S. Rozanov, T. V. Ivanisenko, A. V. Bryanskaya, S. V. Shekhovtsov, M. D. Logacheva, O. V. Saik, T. K. Malup, P. S. Demenkov, T. N. Goryachkovskaya, V. A. Ivanisenko, S. E. Peltek

“…Fragments associated with hemicellulases (endoxylanase, beta xylosidase, and arabinofuranosidase) and the endoxylanase enzyme were detected.…”
Get full text

Co-targeting of metabolism using dietary and pharmacologic approaches reduces breast cancer metastatic burden by Qianying Zuo, Jin Young Yoo, Erik R. Nelson, Matthew J. Sikora, Rebecca B. Riggins, Zeynep Madak-Erdogan

“…We found that Fulv treatment downregulates the ketogenesis pathway enzyme OXCT1, leading to β-hydroxybutyrate accumulation and decreased tumor cell viability. …”
Get full text

An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment by Banu Taskin, Mümin Alper Erdoğan, Gürkan Yiğittürk, Sibel Alper, Oytun Erbaş

“…Digoxin treatment significantly reduced the liver enzyme ALT, plasma TNF-α, TGF-β, PTX3, and MDA levels and decreased histological changes in the liver tissue with MTX-induced hepatotoxicity in the rat model. …”
Get full text

Selectivity of Inhibition of N-Succinyl-l,l-Diaminopimelic Acid Desuccinylase in Bacteria: The product of dapE-gene Is Not the Target of l-Captopril Antimicrobial Activity by Narasimha Rao Uda, Marc Creus

“…Recently, l-captopril has been suggested as a lead compound for inhibition of DapE, although its selectivity for this enzyme target in bacteria remains unclear (Gillner et al. (2009)). …”
Get full text

The Effects of Microplastic Pollution on Marine Organisms and its Impact on Human Health: A Review by Aran Akbari, Jalil Jaafari

“…Exposure of marine organisms to MPs can lead to weight loss, reduced growth, reduced reproduction, changes in feeding behavior, changes in enzyme activity, initiation of stress response, and inflammatory response. …”
Get full text

FDA’s approval of resmetirom (Rezdiffra): a breakthrough in MASH management by Muhammad Mazhar Azam, Sameen Mukhtar, Muhammad Haris, Fatima Laique, Suhaina Amir, Mubashir Mohiuddin, Bibek Giri

“…This mechanism effectively reduces fibrosis markers, improves liver enzyme levels, and minimizes liver fat buildup. Clinical trials have shown that resmetirom has a favorable safety profile, with manageable side effects like diarrhea and nausea. …”
Get full text

Angioedema due to enalapril. A case report by Belkis Barrios Romero, Ana María Ramos Cedeño, Yeny Dueñas Pérez, Mirtha Amarilis Hernández López

“…Angiotensin converting enzyme inhibitors are used by more than 40 million people worldwide for the treatment of cardiovascular diseases. …”
Get full text

Active learning-assisted directed evolution by Jason Yang, Ravi G. Lal, James C. Bowden, Raul Astudillo, Mikhail A. Hameedi, Sukhvinder Kaur, Matthew Hill, Yisong Yue, Frances H. Arnold

“…We apply ALDE to an engineering landscape that is challenging for DE: optimization of five epistatic residues in the active site of an enzyme. In three rounds of wet-lab experimentation, we improve the yield of a desired product of a non-native cyclopropanation reaction from 12% to 93%. …”
Get full text

Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis by Joachim Sieper, Juergen Braun

“…This is much supported by the role of the endoplasmic reticulum aminopeptidase 1 (ERAP 1) in AS, an enzyme that is responsible for the intracellular trimming of peptides, since polymorphisms of this gene are only associated with HLA-B27+ disease. …”
Get full text

Overview of Novel Antipsychotic Drugs: State of the Art, New Mechanisms, and Clinical Aspects of Promising Compounds by Letizia Biso, Marco Carli, Marco Scarselli, Biancamaria Longoni

“…In particular, we analyzed the main classes of investigational antipsychotics, such as monoamine, glutamate, acetylcholine, cannabinoid receptor modulators, enzyme inhibitors, ion channel modulators, and mixed receptor modulators. …”
Get full text

Low-Dose Fluvastatin Prevents the Functional Alterations of Endothelium Induced by Short-Term Cholesterol Feeding in Rabbit Carotid Artery by Gulnur Sevin, Yasemin Delen Akcay, Gonen Ozsarlak-Sozer, Mukadder Yasa

“…In this study, we investigated the effects of low-dose fluvastatin on antioxidant enzyme activities (superoxide dismutase, SOD; catalase), total nitrite/nitrate levels, and vascular reactivity in 2% cholesterol-fed rabbits. …”
Get full text

The Role of Sulfatides in Liver Health and Disease by Lin Chen, Montserrat Elizalde, Gloria Alvarez-Sola

“…We have recently demonstrated how loss of function of GAL3ST1, a limiting enzyme involved in sulfatide synthesis, reduces tumorigenic capacity in cholangiocarcinoma (CCA) cells. …”
Get full text

Matched serum- and urine-derived biomarkers of interstitial cystitis/bladder pain syndrome. by Tadeja Kuret, Igor Sterle, Rok Romih, Peter Veranič

“…A total of 33 different biomarkers were measured, including cytokines and chemokines, proteins involved in extracellular matrix remodeling, adhesion molecules, growth factors, and markers of oxidative stress using enzyme linked immunoassays and multiplex technology. …”
Get full text

Physiochemical Studies of Sodium Chloride on Mungbean (Vigna radiata L. Wilczek) and Its Possible Recovery with Spermine and Gibberellic Acid by Srijita Ghosh, Sanglap Mitra, Atreyee Paul

“…Salt toxicity severely affected activities of different antioxidant enzymes and oxidative stress markers. Activities of antioxidant enzymes, superoxide dismutase (SOD), and catalase (CAT) increased significantly over water control. …”
Get full text

Forced Air Precooling Enhanced Storage Quality by Activating the Antioxidant System of Mango Fruits by Jian Li, Yingli Fu, Jiaqi Yan, Huanlu Song, Weibo Jiang

“…Biochemical studies revealed that precooling treatment could eliminate reactive oxygen species (ROS) effects by enhancing related antioxidant enzyme activities, such as superoxide dismutase (SOD), catalase (CAT), peroxidase (POD), glutathione reductase (GR), and polyphenoloxidase (PPO). …”
Get full text