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1221
DNA algorithm of primeness test based on finite automaton
Published 2006-01-01“…Finite automaton,a computational model of extremely limited computing ability,was proved to have the capa-bility of solving primeness test by construction.Then,a DNA algorithm of the primeness test based on finite automaton was proposed.Furthermore,the method of constructing the finite automaton was presented in detail.The state of the fi-nite automaton was encoded by single-stranded DNA.The input was encoded by double-stranded DNA.The transition rule was represented by a double strand with a ring.The state of transition was realized by enzyme-mediated chemical reactions.The innovation of the algorithm is that it can be applied not only in primeness test but also in prime factoriza-tion and further in attack of RSA cipher.The advantage of this method is that it can be easily implemented.The time re-quired is polynomial in the size of the problem instead of exponential in the size of the problem.…”
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1222
Myeloid ACAT1/SOAT1: a novel regulator of dyslipidemia and retinal neovascularization
Published 2025-01-01“…We show that OIR-induced activation of macrophage/microglial cells, retinal inflammation, and pathological RNV are mediated by increases in cholesterol ester (CE) formation due to activation of the acyl-CoA: Cholesterol Acyltransferase 1/Sterol O-Acyltransferase 1 (ACAT1/SOAT1) enzyme.…”
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1223
Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
Published 2021“…The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H2O2 induced oxidative stress in Drosophila melanogaster flies was assessed. …”
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1224
Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress...
Published 2025-01-01“…Little is known about the consequences of deleting the KYN enzyme gene. …”
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1225
Evaluation of corn steep liquor on the digestibility and growth performance of juvenile common carp strain Sinyonya
Published 2024-07-01“… This study aimed to observe the digestibility performance, digestive enzyme activity, and growth performance of the common carp using corn-steep liquor (CSL). …”
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1226
Angiotensin Inhibition Reduces the Risk of Subarachnoid Hemorrhage in Patients With Hypertension
Published 2025-01-01“…We collected medication history, and the exposure of interest was the use of an angiotensin‐converting enzyme inhibitor or angiotensin receptor blocker (ACEI/ARB). …”
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1227
Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase from Klebsiella pneumoniae
Published 2025-02-01“…ABSTRACT In all kingdoms of life, the enzyme uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central role in metabolism, as its reaction product uridine diphosphate-glucose (UDP-Glc) is involved in various crucial cellular processes. …”
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1228
Impact of Feeding Frequency on Growth Performance and Antioxidant Capacity of <i>Litopenaeus vannamei</i> in Recirculating Aquaculture Systems
Published 2025-01-01“…Among automatic feeding groups, A6 and A8 showed optimal performance, with a quadratic regression identifying 7.83 times/day as the optimal frequency. While digestive enzyme activity remained consistent across groups, A6 and A8 demonstrated significantly higher antioxidant enzyme levels (superoxide dismutase (SOD) and glutathione peroxidase (GPx)) and lower lipid peroxidation (MDA), suggesting superior digestive and antioxidant capacities. …”
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1229
Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off‐target effects
Published 2025-01-01“…We compared the effects of treatment with two of the reportedly most KDAC‐selective inhibitors, Tubastatin A and PCI‐34051, in HT1080 cells in which the endogenous KDAC6 or KDAC8 gene has been mutated to inactivate enzyme catalysis while retaining enzyme expression. …”
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1230
Synthesis of Anti-Inflammatory Drugs’ Chalcone Derivatives and a Study of Their Conformational Properties Through a Combination of Nuclear Magnetic Resonance Spectroscopy and Molec...
Published 2025-01-01“…Background: In this study, two chalcone analogs were synthesized through in silico and experimental methods, and their potential to inhibit the lipoxygenase enzyme, which plays a role in the inflammation pathway, was assessed. …”
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1231
Effects of green manuring on chemical characteristics and microecology of tobacco-growing soil in central henan
Published 2025-01-01“…Abstract Objective This study explored green manuring effects on microecology, carbon/nitrogen levels, and enzyme activity in tobacco-growing soils. Methods After 30,000 kg·hm⁻² overpressure and 28 days of natural decomposition, plants (Hordeum vulgare L. …”
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1232
Biochemical and technological properties of moose (<i>Alces alces</i>) recombinant chymosin
Published 2022-06-01“…Commercial rСhns of cow and camel were used as comparison enzymes. In some technological parameters, the moose rChn proved to be superior to the reference enzymes. …”
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1233
Chemical Profiling and Biological Activities on Nepalese Medicinal Plant Extracts and Isolation of Active Fraction of Nyctanthes arbor-tristis
Published 2024-01-01“…The antidiabetic activity was studied by the α-amylase enzyme inhibition assay. The highest antioxidant activity was observed in extracts of Nyctanthes arbor-tristis followed by Mallotus philippensis (seed cover), Pogostemon benghalensis, Litsea monopetala, Phoenix humilis, and Neolamarckia cadamba with IC50 values of 27.38 ± 1.35, 32.08 ± 2.81, 32.75 ± 2.13, 33.82 ± 1.07, 40.14 ± 0.93, and 50.44 ± 3.75 µg/mL, respectively. …”
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1234
Kriptokokal meningitis: Aspek klinis dan diagnosis laboratorium
Published 2012-07-01“…Laboratory tests for cryptococcosis diagnosis is direct microscopic examination using India ink, antigen detection, enzyme immunoassay, culture, and molecular methods. …”
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1235
Molecular Mechanism of Germinated Foxtail Millet Bioactive Peptides in Attenuating Copper-induced Oxidative Damage in Caenorhabditis elegans
Published 2025-01-01“…Conclusions: This study demonstrates that germinated millet bioactive peptides can effectively alleviate copper-induced oxidative damage, possibly through enhancing the activity of antioxidant enzymes, reducing the expression of cuticle and cytochrome enzyme P450 related genes, and regulating the content of plant secondary metabolites.…”
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1236
Management of Hypertension in the Elderly Patient at Abidjan Cardiology Institute (Ivory Coast)
Published 2012-01-01“…When ≥2 drugs were used, diuretics and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers were the most common. …”
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1237
Identification of musk compounds as inhibitors of the main SARS-CoV-2 protease by molecular docking and molecular dynamics studies
Published 2024-01-01“…With this in mind, we have systematically screened potential odorant molecules in the treatment of this infection based on the affinity of the selected odorant compounds on the studied enzyme and the sequence identity of their target proteins (olfactory receptors) to the same enzyme (the main protease of SARS-CoV-2). …”
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1238
Salinity affects the lipid metabolism and intestinal microbial composition of swimming crab Portunus trituberculatus
Published 2025-03-01“…The results showed that the highest expression level of SREBP1, FAS, LPR1, ACOX and FABP was found in 19 ‰ group compared to the 28 ‰ group, along with the enzyme activities of CPT1 and FAS. On the contrary, the expression level of DGAT1 and LPR2 in the 28 ‰ group was significantly higher than that of 19 ‰ group, along with the enzyme activities of LPS. …”
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1239
The effects of Bifidobacterium animalis QC08 on reducing uric acid level and providing renal protection in mice with hyperuricemia
Published 2025-01-01“…The serum levels of uric acid (UA), blood urea nitrogen (BUN), creatinine (Cr), and liver xanthine oxidase (XO) were measured in four groups, including normal group, control group, allopurinol group (5 mg/kg), and Bifidobacterium animalis QC08 group (1010 CFU/kg) using enzyme colorimetry. Additionally, serum tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) levels were assessed using enzyme-linked immunosorbent assay (ELISA). …”
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1240
Τhiazolidine-4-One Derivatives with Variable Modes of Inhibitory Action Against DPP4, a Drug Target with Multiple Activities and Established Role in Diabetes Mellitus Type II
Published 2025-01-01“…<b>Background/Objectives:</b> DPP4 is an enzyme with multiple natural substrates and probable involvement in various mechanisms. …”
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