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Iron- Refractory Iron Deficiency Anemia: Review Article
Published 2024-07-01“…Background: IRIDA is an inherited recessive anaemia caused by a defect in the TMPRSS6 gene, which codes for the enzyme matriptase-2. This transmembrane serine protease suppresses hepcidin production, an iron regulator (suppressing intestinal absorption of iron). …”
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1222
The Impact of COVID-19 on Gametes and Endometrium: A Narrative Review
Published 2023-03-01“…Whereas the available data suggest that SARS-CoV-2 interferes with various types of molecular pathways in the oocyte, spermatozoa, and endometrium, the lack of co-expression in angiotensin-converting enzyme 2 and transmembrane protease serine 2 in those cell lines theoretically avoid concerns by patients and reproductive endocrinologists. …”
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1223
Risk of Cardiovascular Diseases in Diabetes Mellitus and Serum Concentration of Asymmetrical Dimethylarginine
Published 2013-01-01“…Serum ADMA was analyzed by using enzyme immunoassay for the quantitative determination of endogenous ADMA, and serum nitric oxide was estimated by the method of Cortes. …”
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1224
The Effect of Lyso-PAF on Ciliary Activity of Human Paranasal Sinus Mucosa in vitro
Published 1994-01-01“…These findings indicated the existence of an enzyme in the paranasal sinus mucosa, by which lyso-PAF is converted to PAF, and that lyso-PAF can inhibit ciliary activity by means of PAF.…”
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1225
Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development
Published 2011-01-01“…Here, we discuss the interrelated nature of this critical enzyme with iron trafficking, erythroid cell function, and embryonic survival.…”
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1226
Genotypic and Phenotypic Assessment of Hyaluronidase among Type Strains of a Select Group of Staphylococcal Species
Published 2009-01-01“…These data support the hypothesis that among members of the Staphylococcus genus only strains of S. aureus possess the enzyme hyaluronidase. This would suggest that hyaluronidase represents yet another potential virulence factor employed by S. aureus to cause disease and may represent a diagnostically important characteristic for distinguishing S. aureus from other members of this genus.…”
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1227
Hypoxia-Induced Reactive Oxygen Species: Their Role in Cancer Resistance and Emerging Therapies to Overcome It
Published 2025-01-01“…Hypoxia-induced ROS, resulting from mitochondrial dysfunction and enzyme activation, exacerbates genomic instability, tumor aggressiveness, and therapy resistance. …”
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1228
Validation of a triiodothyronine (T3) ELISA for mouse fecal samples
Published 2024-11-01“…We demonstrated that using a methanol extraction protocol produced the most reliable fecal T3 measurement in an enzyme‐linked immunosorbent assay (ELISA). We found that during a thyroid hormone‐treated state, fecal and plasma T3 measurements from mice are directly related, while during a methimazole‐treated state, fecal and plasma T3 measurements from mice are inversely related. …”
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1229
Development of Automatic 3D Blood Vessel Search and Automatic Blood Sampling System by Using Hybrid Stereo-Autofocus Method
Published 2012-01-01“…Additionally, we established an automatic blood sampling system for SMBG and assessed its performance in relation to punctures, blood suction, transport, and discharge on an enzyme sensor. The 3D BVS and automatic blood sampling system are adequate for use in a portable SMBG device.…”
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1230
Implementation of a Methodology for the Detection of Biochemical Markers in Type 1 Tyrosinemia
Published 2023-11-01“…<strong>Foundation:</strong> hereditary tyrosinemia type I or hepato-renal tyrosinemia is an autosomal recessive disease caused by deficiency of the enzyme fumarylacetoacetate hydrolase. Due to its metabolic complexity, its confirmation requires a set of highly expensive methods. …”
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1231
Dynamic Production of Soluble Extracellular Polysaccharides by Streptococcus mutans
Published 2011-01-01“…Microtiter well plates were coated with cell-free supernatants followed by the addition of labeled Concanavalin-A and enzyme substrate. The substrate reactions were kinetically detected at 405 nm. …”
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1232
Potential therapeutic effect of thymoquinone on cisplatin-induced hepatotoxicity in rats
Published 2024-03-01“…<p> <b>Results: </b>CIS application increased liver enzyme levels, histopathological changes, inflammation, oxidative stress and apoptosis in liver tissue and caused a decrease in OTULIN level. …”
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1233
Mice with Catalytically Inactive Cathepsin A Display Neurobehavioral Alterations
Published 2017-01-01“…A mutant mouse with catalytically inactive CathA enzyme (CathAS190A) shows increased levels of endothelin-1. …”
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1234
Transglutaminase 2 Induces Deficits in Social Behavior in Mice
Published 2018-01-01“…In the present study, we examined the role of transglutaminase 2 (TG2), a calcium-dependent enzyme known to be induced following ER stress, in social behavior in mice. …”
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1235
Tocilizumab-Induced Acute Liver Injury in Adult Onset Still’s Disease
Published 2013-01-01“…Mild to moderate liver enzyme elevation is a well-known side effect, but severe liver injury has only been reported in 3 cases in the literature. …”
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1236
IL-6 Promotes Islet β-Cell Dysfunction in Rat Collagen-Induced Arthritis
Published 2016-01-01“…Furthermore, in line with the upregulated IL-6 expression, the apoptosis related enzyme caspase-3 was also markedly increased. These data showed that the elevated FBG in CIA may be associated with the reduced FIns level secondary to the overapoptosis of pancreas islet cells induced by IL-6.…”
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1237
Leukocyte Production of Inflammatory Mediators Is Inhibited by the Antioxidants Phloretin, Silymarin, Hesperetin, and Resveratrol
Published 2014-01-01“…Peripheral blood mononuclear cells were stimulated with lipopolysaccharide purified from Aggregatibacter actinomycetemcomitans, and the production of cytokines, chemokines, and differentiation factors was assayed by enzyme-linked immunosorbent assay, cytometric bead array, and RT-PCR. …”
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1238
Production of Laccase by Cochliobolus sp. Isolated from Plastic Dumped Soils and Their Ability to Degrade Low Molecular Weight PVC
Published 2016-01-01“…Several fungi have been identified that produce enzymes capable of plastic degradation in various laboratory conditions. …”
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1239
Identification and Evaluation of Strain B37 of Bacillus subtilis Antagonistic to Sapstain Fungi on Poplar Wood
Published 2014-01-01“…After being experimented with agar plates, wood chips, and enzyme activities, strain B37 was identified as the best poplar sapstain biocontrol bacterium. …”
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1240
Advances in Research on the Interaction of Food-derived Polysaccharide and Polyphenol
Published 2025-02-01“…This paper describes the means of characterizing food-derived polysaccharide and polyphenol interactions, including Fourier transform infrared (FT-IR) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy, and interaction mechanisms such as enzyme-catalyzed reactions and free radical-induced reactions was also summarized. …”
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