Accelerated Growth Rate Induced by Neonatal High-Protein Milk Formula Is Not Supported by Increased Tissue Protein Synthesis in Low-Birth-Weight Piglets by Agnès Jamin, Bernard Sève, Jean-Noël Thibault, Nathalie Floc’h

“…Higher growth rate was associated with higher feed conversion and reduced protein synthesis rate in the small intestine, muscle and carcass, whereas proteolytic enzyme activities measured in these tissues were unchanged. …”
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A Butyrylcholinesterase Camera Biosensor Tested for Carbofuran and Paraoxon Assay by Miroslav Pohanka, Jitka Zakova

“…In this paper, a colorimetric biosensor is constructed using 3D-printed multiwell pads treated with indoxylacetate as a chromogenic substrate and gold nanoparticles with the immobilized enzyme butyrylcholinesterase. A smartphone camera served for photogrammetry. …”
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High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana by Naomi Hauser, Tanmay Sahai, Rocco Richards, Todd Roberts

“…Tacrolimus has a narrow therapeutic index with variable oral bioavailability and metabolism via cytochrome P-450 3A enzyme. Toxicity can occur from overdosing or from drug-drug interactions with the simultaneous administration of cytochrome P-450 3A inhibitors and possibly P-glycoprotein inhibitors. …”
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Pear Fruits Ripening Response to Ethylene and Temperature Treatments by Ikbal MuhammedGharib Tahir

“…Results indicate that compote variety was differing significantly in decreasing weight loss and fruits firmness and increasing fruits peel pigments content and peroxidase enzyme activity compared to spadona variety. Slower ripening process was gained from cold storage treatment where the fruits remain non-ripened compared to other treatments, whereas ripening fruits at 20C° for 12 days fastened the ripening process by giving highest TSS, and lowest fruits firmness, in addition to percent of weight loss. …”
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Metabolic Analysis of the Mode of Action and Mode of Resistance for Novobiocin in Staphylococcus aureus by Weile Xie, Dan Luo, Zhe Wang

“…Targeting of bacterial gyrase, specifically the gyrB subunit, is a promising approach because of this enzyme’s essential role in bacterial DNA replication and its absence in higher eukaryotes. …”
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COVID-19 Pandemic and Irritable Bowel Syndrome — is there a Relationship? by V. A. Akhmedov

“…It has been noted that the COVID-19 may contribute to the formation of post-infectious functional gastrointestinal diseases, given that angiotensin-converting enzyme-2 (ACE-2) receptors, the site of binding of the SARS-CoV-2 virus to human cells, are also present in epithelial intestinal cells; virus was found in feces in about half of patients, gastrointestinal symptoms, including diarrhea occur in about one fifth of patients, fecal calprotectin, a marker of GI inflammation is elevated in patients with COVID-19, macroscopically as well as histologically, patients show signs of damage mucous membrane of the gastrointestinal tract, and also, as noted above, they have a dysbiosis of the intestinal microbiota.Conclusion. …”
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Gastrointestinal Disturbances Associated with the Consumption of Sugar Alcohols with Special Consideration of Xylitol: Scientific Review and Instructions for Dentists and Other Hea... by Kauko K. Mäkinen

“…Adaptation may take place as a result of enzyme induction in the intestinal flora. Some of the literature on xylitol has been difficult to access by health-care professionals and will be reviewed here. …”
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Age-Dependent Paraoxonase 1 (PON1) Activity and LDL Oxidation in Wistar Rats during Their Entire Lifespan by Dileep Kumar, Syed Ibrahim Rizvi

“…Paraoxonase 1 (PON1) is an HDL bound enzyme which plays a key role in the protection of LDL and HDL from oxidation by hydrolyzing activated phospholipids and lipid peroxide products. …”
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Study on the Synergistic Regulation Model for <i>Lycium barbarum</i> Berries Under Integrated Irrigation and Fertigation in Northwest Arid Regions by Yanlin Ma, Huile Lv, Yanbiao Wang, Yayu Wang, Minhua Yin, Yanxia Kang, Guangping Qi, Rong Zhang, Jinwen Wang, Junxian Chen

“…W2 had the highest soil enzyme activities, yielding 4.41–42.86% more than other levels, with maximum efficiencies for WUE, GUE, NUE, and NAE. …”
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Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine sett... by Sara Amiranda, Mariangela Succoio, Serenella Anzilotti, Ornella Cuomo, Tiziana Petrozziello, Valentina Tedeschi, Arianna Finizio, Giorgia Mele, Seppo Parkkila, Lucio Annunziato, Giuseppina De Simone, Giuseppe Pignataro, Agnese Secondo, Nicola Zambrano

“…A focus on carbonic anhydrase IX showed that ischemic stress altered subcellular distributions of this enzyme in rodent neuronal populations. Given the enzyme's canonical membrane localization, we implemented pharmacological inhibition using a membrane-impermeant sulfonamide inhibitor in neuronal models of brain ischemia. …”
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Structural basis of FpGalNase and its combination with FpGalNAcDeAc for efficient A-to-O blood group conversion by Meiling Zhou, Kaishan Luo, Chao Su, Yan Sun, Zuyan Huang, Shuo Ma, Xun Gao, Jiwei Wang, Chen Zhang, Pengcheng Han, Guoqiu Wu

“…However, the major obstacle to this strategy is the relatively low catalytic efficiency of the enzymes involved. In this study, we investigated two enzymes from Flavonifractor plautii, N-acetylgalactosamine deacetylase (FpGalNAcDeAc) and galactosaminidase (FpGalNase), which demonstrate synergistic activity in efficiently converting A-type RBCs to O-type. …”
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Alleviating <i>Clostridium perfringens</i>-Induced Intestinal Lesions in Chickens Using the Xylanase <i>Cb</i>Xyn10C and Its Binary Cocktail with a Protease by Wenjing Zhang, Zhenzhen Hao, Daoxin Yang, Wangli Ji, Kairui Guo, Xianhua Sun, Shuai Wang, Shuyan Yang, Jianshuang Ma, Tong Wang, Huiying Luo, Bin Yao, Meiling Zhang, Yuan Wang, Huoqing Huang, Xiaoyun Su

“…Not unexpectedly, feeding enzymes influenced the abundance of <i>Lactobacillus</i> and <i>Butyricicoccus</i> bacteria in the intestine. …”
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Utilization of hydrolyzed corncob as a carbohydrate source in diets for red Nile tilapia Oreochromis niloticus by Fauzan, Muhammad Agus Suprayudi, Ichsan Achmad Fauzi, Julie Ekasari

“…The first study step was enzymatic hydrolysis using 0.4 g/kg cocktail enzyme, followed by chemical hydrolysis using hydrochloric acid (HCl) at different treatments, i.e. concentration, incubation period, and ratio. …”
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The influence of biofloc system on Vibrio composition, the growth and the gut microvilli performance of the Pacific white shrimp Penaeus vannamei by Muhamad Gustilatov, Widanarni Widanarni, Julie Ekasari, Pande Gde Sasmita Julyantoro, Diana Elizabeth Waturangi

“…The biofloc system significantly increased the digestive enzyme activity, growth performance, and microvilli length in the shrimp gut. …”
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Natural Product Identification and Molecular Docking Studies of Leishmania Major Pteridine Reductase Inhibitors by Moses N. Arthur, George Hanson, Emmanuel Broni, Patrick O. Sakyi, Henrietta Mensah-Brown, Whelton A. Miller, Samuel K. Kwofie

“…<b>Background/Objectives</b>: Pteridine reductase 1 (PTR1) has been one of the prime targets for discovering novel antileishmanial therapeutics in the fight against Leishmaniasis. This enzyme catalyzes the NADPH-dependent reduction of pterins to their tetrahydro forms. …”
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Effect of seed priming and foliar application of organic liquid manure on germination, growth, yield and quality of late-sown wheat by Okram Ricky Devi, Omvati Verma, Bibek Laishram, S. Anbarasan, Abhijit Debnath, Narinder Panotra, Priyanka Elumle, Sunita T. Pandey, R. Ajaykumar, Samreen

“…From the information presented above, it can be inferred that seed priming with 10% HK along with 100% of the recommended dose of nutrients, followed by foliar applications of 10% HK at various growth stages, increased the growth, productivity and enzyme activity of late sown wheat that priming with 10% HK and its foliar application under 100% RDN increased the growth, productivity, grain quality indices, enzyme activities, and economic profitability of late-sown wheat. …”
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Strategies for preventing and managing osteoporosis in elderly breast cancer patients undergoing aromatase inhibitor therapy by Andi Tian, Chunyu Zhang

“…Aromatase, a critical enzyme in estrogen biosynthesis, exhibits heightened expression in breast tumors and their surrounding tissues. …”
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Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer by K. C. Masoumi, Gina Shaw-Hallgren, Ramin Massoumi

“…Basal cell carcinoma and squamous cell carcinoma, the most common types of human skin cancer, are instances where the involvement of the deubiquitination enzyme CYLD has been recently highlighted. In basal cell carcinoma, the tumor suppressor protein CYLD is repressed at the transcriptional levels through hedgehog signaling pathway. …”
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Analysis of HIV therapy in the liver using optimal control and pharmacokinetics by Hasifa Nampala, Matylda Jabłońska-Sabuka, Martin Singull

“…The study recommends routine transaminase tests because results indicate liver enzyme elevation even with very low viral load. Numerical results with pharmacokinetic parameters further indicate an increase in HIV load at initiation of therapy, due to viral redistribution in plasma.…”
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An optimized CTAB method for genomic DNA extraction from green seaweeds (Ulvophyceae) by Riyad Hossen, Myles Courtney, Alasdair Sim, Md Abdullah Al Kamran Khan, Heroen Verbruggen, Trevor Bringloe

“…Our method, involving an initial sample treatment, lysis buffer adjustment, and enzyme incubation alterations, outperformed the conventional CTAB and commercial kits in terms of DNA yield and purity. …”
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