Chromosome-Level Genome Assembly and Annotation of the Highly Heterozygous <i>Phallus echinovolvatus</i> Provide New Insights into Its Genetics by Mengya An, Ruoxi Liang, Yanliu Chen, Jinhua Zhang, Xiuqing Wang, Xing Li, Guohua Qu, Junfeng Liang

“…The Monop had a size of 36.54 Mb, with 10,251 predicted protein-coding genes and including 433 carbohydrate-active enzyme genes, 385 cytochrome P450 enzyme genes, and 42 gene clusters related to secondary metabolite synthesis. …”
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Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neu... by Zohre Aghaei, Narges Karbalaei, Mohammad Reza Namavar, Masoud Haghani, Mahboobeh Razmkhah, Mahdi Khorsand Ghaffari, Marzieh Nemati

“…Colorimetric assays were used to determine hippocampus glutathione (GSH), malondialdehyde (MDA) levels, and antioxidant enzyme activity. The histopathological evaluation of the hippocampus was performed by Nissl staining. …”
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Neutral drift upon threshold-like selection promotes variation in antibiotic resistance phenotype by Ayşe Nisan Erdoğan, Pouria Dasmeh, Raymond D. Socha, John Z. Chen, Benjamin E. Life, Rachel Jun, Linda Kiritchkov, Dan Kehila, Adrian W. R. Serohijos, Nobuhiko Tokuriki

“…We perform long-term experimental evolution on VIM-2 β-lactamase, an antibiotic-resistance enzyme, to explore the conditions that promote the emergence and maintenance of phenotypic variation. …”
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Study the Effect of Exogenous Iodine on the Thyroid Transcription Factors during Pregnancy in Rat Model by Ghina Hamoodi Hussein, Ehab R. Muhssa, Alaa T. Shakir

“…Objective: Thyroid transcription factors were be measured by an enzyme-linked immunosorbent assay technique in all studied samples. …”
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The gonad growth of Anguilla bicolor bicolor induced by hormone combination of HCG, MT, E2, and antidopamine by Abdul Zahri, Agus Oman Sudrajat, Muhammad Zairin Junior

“…Estradiol concentration in the blood serum were measured by enzyme-linked immunosorbent assay (ELISA). Stimulation with hCG 20 IU/kg in combination with MT 3 mg/kg and 10 μg/kg antidopamine (hTA treatment) very effective for increased the growth of gonads with indicators gonadosomatic index (GSI) of 4.80%, hepatosomatic index 1.01% and concentration of E2 2.49±0.67 ng/mL were significantly different (P<0.05) than others treatment after ten weeks of application.   …”
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Melanin production and laccase mediated oxidative stress alleviation during fungal-fungal interaction among basidiomycete fungi by Samim Dullah, Dibya Jyoti Hazarika, Gunajit Goswami, Tanushree Borgohain, Alokesh Ghosh, Madhumita Barooah, Ashok Bhattacharyya, Robin Chandra Boro

“…Further, increased activity of superoxide dismutase, an enzyme that catalyzes the dismutation of the superoxide anion to hydrogen peroxide was also recorded during fungal–fungal interaction. …”
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Multiple mutations in polyketide synthase led to disruption of Psittacofulvin production across diverse parrot species by Shatadru Ghosh Roy, Jindřich Brejcha, Petr Maršík, Anna Bakhrat, Moty Abdu, Roberto Arbore, Pedro Miguel Araújo, Sandra Afonso, Miguel Carneiro, Iris Grossman-Haham, Uri Abdu

“…Abstract Polyketide synthases (PKSs) are crucial multidomain enzymes in diverse natural product biosynthesis. Parrots use a type I PKS to produce a unique pigment called psittacofulvin in their feathers. …”
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Hydrolysis of fish waste using fruit wastes of Ananas comosus and Carica papaya for the formulation of liquid fertilizers by RHAA Ranasinghe, BTSDP Kannagara, RMCS Ratnayake

“…Results Ananas comosus ripe fruit peels and the mixture of (A. comosus + C. papaya) showed the highest enzyme activities (0.33±0.02 and 0.36±0.01 U mL-1 enzyme respectively) at 55 oC and 70 oC. …”
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Molecular Detection and Phylogenetic Analysis of the alkB Gene in Klebsiella oxytoca Strains Isolated from the Gut of Tenebrio molitor by Tsitsi Lynn Mupamhadzi, Oleen Machona, Farisai Chidzwondo, Rumbidzai Mangoyi

“…The alkB gene encodes for alkane-1-monooxygenase, an enzyme involved in the oxidation of inactivated alkanes. …”
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Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN by Yiolanda-Panayiota Christou, George A. Tanteles, Elena Kkolou, Annita Ormiston, Kostas Konstantopoulos, Maria Beconi, Randall D. Marshall, Horacio Plotkin, Kleopas A. Kleopa

“…PKAN is caused by biallelic PANK2 mutations, a gene that encodes pantothenate kinase 2, a regulatory enzyme in coenzyme A biosynthesis. Current therapeutic strategies rely on symptomatic relief. …”
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Steering acidic oxygen reduction selectivity of single-atom catalysts through the second sphere effect by Haiyuan Zou, Siyan Shu, Wenqiang Yang, You-chiuan Chu, Minglun Cheng, Hongliang Dong, Hong Liu, Fan Li, Junhui Hu, Zhenbin Wang, Wei Liu, Hao Ming Chen, Lele Duan

“…Abstract Natural enzymes feature distinctive second spheres near their active sites, leading to exquisite catalytic reactivity. …”
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Chemical composition by PTP 1B inhibitory activity guided analysis of a plant- based antidiabetic polyherbal drug used in ethnomedical systems by Pardon Mugari, Pamhidzai Dzomba, Stephen Nyoni

“…The anthocyanins inhibited PTP 1B enzyme significantly better than metformin with percentage inhibition of 88.2 ± 3.2, 90.3 ± 2.3 and 93.6 ± 2.9%. …”
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TMPRSS2 as a Key Player in Viral Pathogenesis: Influenza and Coronaviruses by Gilmara Barros de Lima, Everton Nencioni, Fábio Thimoteo, Camila Perea, Rafaela Fuzaro Alves Pinto, Sergio Daishi Sasaki

“…TMPRSS2, a human transmembrane protease enzyme, plays a crucial role in the spread of certain viruses, including influenza and coronaviruses. …”
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Identifying novel heterozygous PI4KA variants in fetal abnormalities by Chen Cheng, Fan Yang, Xinlin Chen, Sheng Zhao

“…Functional studies confirmed that the identified variant induces alterations in RNA splicing and impairs enzyme activity.…”
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Wharton’s Jelly Mesenchymal Stem Cell Conditioned Medium Ameliorates Diabetes-Induced Testicular Damage and Sperm Abnormalities by Mitigating Oxidative Stress, Apoptosis, and Infla... by Mojtaba Sargazi, Narges Karbalaei, Saied Karbalay-Doust, Sara Keshtgar, Zohre Aghaei

“…Sex hormones, testicular antioxidant enzyme activity, malondialdehyde (MDA), and glutathione (GSH) concentrations were measured using colorimetric methods. …”
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Binding Mode Investigation of Polyphenols from Scrophularia Targeting Human Aldose Reductase Using Molecular Docking and Molecular Dynamics Simulations by Abinaya Manivannan, Prabhakaran Soundararajan, Yoo Gyeong Park, Sugunadevi Sakkiah, Byoung Ryong Jeong

“…Aldose reductase (ALR2), a vital enzyme involved in polyol pathway, has befitted as a novel drug target in antidiabetes drug discovery process. …”
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Advancing the accuracy of tyrosinase inhibitory peptides prediction via a multiview feature fusion strategy by Watshara Shoombuatong, Nalini Schaduangrat, Nutta Homdee, Saeed Ahmed, Pramote Chumnanpuen

“…Abstract Tyrosinase plays a crucial role as an enzyme in the production of melanin, which is the pigment accountable for determining the color of the hair, eyes, and skin. …”
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Assessment of the Effects of Chemotherapy on Ovarian Reserve in Rats by Ahmet Mete Ergenoğlu, Özgür Yeniel, Volkan Turan, Gülşah Demirtaş, Levent Akman, Mustafa Coşan Terek, Gülinnaz Ercan, Osman Zekioğlu

“…The levels of MDA were significantly lower compared to the other groups (p<0.001); however, the catalase enzyme activities did not show statistically significant difference. …”
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Potential Piperolactam A Isolated From Piper betle as Natural Inhibitors of Brucella Species Aminoacyl‐tRNA Synthetase for Livestock Infections: In Silico Approach by Diding Latipudin, Sefren Geiner Tumilaar, Yoga Ramdani, Dudi Dudi, Dikdik Kurnia

“…The result in silico test is that piperolactam A has the potential to inhibit LeuRS enzyme with the greater binding affinity.…”
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Cellular Localization and Biochemical Characterization of a Chimeric Fluorescent Protein Fusion of Arabidopsis Cellulose Synthase-Like A2 Inserted into Golgi Membrane by Monica De Caroli, Marcello S. Lenucci, Gian-Pietro Di Sansebastiano, Michela Tunno, Anna Montefusco, Giuseppe Dalessandro, Gabriella Piro

“…Cellulose synthase-like (Csl) genes are believed to encode enzymes for the synthesis of cell wall matrix polysaccharides. …”
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