The role of exogenous histamine in atopic dermatitis flare-ups by Zofia Kowalska, Joanna Narbutt

“…This review explores the complex relationship between exogenous histamine and AD flare-ups, evaluating evidence for implementing low-histamine diets and diamine oxidase enzyme supplementation as a potential therapeutic intervention in a subgroup of AD patients. …”
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Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases by Weiwei Zhang, Feiqi Zhu, Jie Zhu, Kangding Liu

“…Phospholipase D (PLD) is an enzyme that consists of six isoforms (PLD1–PLD6) and has been discovered in different organisms including bacteria, viruses, plants, and mammals. …”
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A Solution of the Convective-Diffusion Equation for Solute Mass Transfer inside a Capillary Membrane Bioreactor by B. Godongwana, D. Solomons, M. S. Sheldon

“…The results obtained from the application of this model, along with a biofilm growth kinetic model, will be useful in the derivation of an efficiency expression for enzyme production in an MBR.…”
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Pseudomembranous Colitis: An Update by Harpreet S Brar, Christina M Surawicz

“…Thus, many laboratories use the enzyme-linked immunoassay tests to detect toxin of C difficile because they are a more rapid screen. …”
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Back to Natural Fiber: Wool Color Influences Its Sensitivity to Enzymatic Treatment by Amro A. Amara

“…This study is concerning with improving the wool quality using technical enzymes. White wool proves to be more susceptible to the enzymatic treatment than blackish brown wool. …”
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Massive Levemir (Long-Acting) Insulin Overdose: Case Report by Mamatha Oduru, Mahmood Ahmad

“…Overdoses can result in persistent hypoglycaemia, liver enzyme derangement, electrolyte abnormalities, and neurological damage. …”
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Lessons Learned and Questions Raised by an Atypical Case of Clozapine-Induced Myocarditis by Charles H. Earnshaw, Lucy Powell, Owen Haeney

“…A diagnosis of myocarditis was confirmed as a result of elevated cardiac enzyme levels and an echocardiogram. Following withdrawal of clozapine, supportive management, and initiation of cardiac medication, the patient made a successful recovery. …”
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Stimulation of neutrophil functions by C5adesArg: an in vitro model of haemodialysis by I. Eckle, G. Kolb, E. Martinez Martin, K. Havemann

“…C5adesArg generated in vitro by yeast incubation of autologous plasma stimulates PMN chemotaxis and oxidative metabolism but has no effect on enzyme release. Preincubation of whole blood with C5adesArg causes aggregation and changed oxidative burst activity of the isolated PMN. …”
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Discovery of New Ligand with Quinoline Scaffold as Potent Allosteric Inhibitor of HIV-1 and Its Copper Complexes as a Powerful Catalyst for the Synthesis of Chiral Benzimidazole De... by Sabikeh G. Azimi, Ghodsieh Bagherzade, Mohammad Reza Saberi, Zeinab Amiri Tehranizadeh

“…The potency of these compounds as anti-HIV-1 agents was investigated using molecular docking into integrase (IN) enzyme with code 1QS4 and the GROMACS software for molecular dynamics simulation. …”
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Chronic cholecystitis at patients with the various trophological status: mechanisms and feature of clinical course by Ye. V. Anisimova, I. V. Kozlova, S. V. Volkov

“…Food behavior analysis was carried out, clinical features, anthopometry were determined, bile lipid spectrum, serum content of leptin and insulin were studied by enzyme-linked immunoassay.Results. Investigation of gallbladder diseases has objectively demonstrated, that trophological status affects development and course of chronic cholecystitis, but is not the only determining factor.Conclusions. …”
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Noncirrhotic Extrahepatic Portosystemic Shunt Causing Adult-Onset Encephalopathy Treated with Endovascular Closure by Eldad Elnekave, Eugenia Belenky, Lindsley Van der Veer

“…Hepatitis panel, relevant serological tests, tumor markers (CA-19-9, CEA), and urea cycle enzyme studies were unrevealing. Lactulose and rifaximin therapy failed to normalize serum ammonia levels. …”
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Prognostic value of serum cystatin C in patients with sepsis by Chunfang Hu, Zhiyuan Zhang, Bin Hou, Han Xue, Xuehua Pu, Jilu Ye

“…Materials and Methods: The levels of serum cystatin C, C-reactive protein (CRP), and procalcitonin (PCT) were measured via enzyme-linked immunosorbent assay (ELISA). The patients with sepsis were followed up for 30 days to record their survival conditions. …”
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Involvement of different protein kinases and phospholipases A2 in phorbol ester (TPA)-induced arachidonic acid liberation in bovine platelets by M. Lehr, K. Griessbach

“…TPA stimulates arachidonic acid release mainly by activating group IV cytosolic PLA2 (cPLA2), since inhibitors of this enzyme markedly inhibited arachidonic acid formation. …”
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Engineering a bacterial toxin deaminase from the DYW-family into a novel cytosine base editor for plants and mammalian cells by Dingbo Zhang, Fiona Parth, Laura Matos da Silva, Teng-Cheong Ha, Axel Schambach, Jens Boch

“…Truncations result in an extraordinarily small enzyme. The SsdA-base editor efficiently converts C-to-T in rice and barley protoplasts and induces mutations in rice plants and mammalian cells. …”
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Graph-theoretic conditions for zero-eigenvalue Turing instability in general chemical reaction networks by Maya Mincheva, Gheorghe Craciun

“…The technique is illustrated with a model of a bifunctional enzyme.…”
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Preference for and resistance to a toxic sulfur volatile opens up a unique niche in Drosophila busckii by Venkatesh Pal Mahadevan, Diego Galagovsky, Markus Knaden, Bill S. Hansson

“…This adaptability is likely linked to insensitivity of the enzyme complex cytochrome c oxidase (COX), which is a DMDS target in other insects. …”
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Improving breast cancer treatments using pharmacomicrobiomics by Aswin Anand Pai, Aadra Prashant Bhatt

“…The authors present compelling evidence that functional differences in the gut microbiota, specifically the bacterial enzyme β-glucuronidase, leads to inter-individual variability in systemic exposure of tamoxifen, affecting drug efficacy. …”
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Two Mixed-Ligand Cu(II) Polymers: Treatment Activity on Acute Cerebral Infarction Combined with Alteplase by Wen-Ping Liu, Tao Xue, Yangchun Li, Ruoyu Cui

“…Furthermore, the biological activity of compounds was evaluated, and the related mechanism was explored as well. Firstly, the enzyme-linked immunosorbent assay (ELISA) was conducted to measure the content of coagulation factors in the serum after compound treatment. …”
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Comparison of Two Methods for Assaying Reducing Sugars in the Determination of Carbohydrase Activities by Alexander V. Gusakov, Elena G. Kondratyeva, Arkady P. Sinitsyn

“…Using twelve commercial enzyme preparations, the comparison of the NS and DNS assays in determination of cellulase, β-glucanase, xylanase, and β-mannanase activities was carried out. …”
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CYP Gene Expression and In Vivo Biological Effects of Khat Ethanol Extract, Cathinone and Cathine in Caenorhabditis elegans by Sharoen Yu Ming Lim, Mohammed Abdullah Alshawsh, Mustafa Alshagga, Cin Kong, Chee-Mun Fang, Yan Pan

“… The significant influence of khat, cathinone, and cathine on appetite suppression, reproduction impairment, and inhibitory effects on CYPs enzyme activity is widely recognised, but much remains unknown about its mode of action. …”
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