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1021
In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (Zn...
Published 2025-02-01“…Fluorescence enzymatic assays were carried out to quantify enzyme activities in vitro. The results indicated that ZnO particles inhibited the tested P450 isozymes with varying potencies. …”
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1022
Non-carbapenem-producing carbapenem-resistant Pseudomonas aeruginosa in children: Risk factors, molecular epidemiology, and resistance mechanism
Published 2025-02-01“…Conclusions: Prolonged hospital stays and an increased exposure to enzyme–inhibitor complex therapies were identified as independent risk factors for CRPA HAIs. …”
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1023
Dichlormid protect wheat from fomesafen residual injury by increasing PPO expression and the photosynthesis characterize
Published 2025-01-01“…The antioxidant enzyme activity of peroxidase, superoxide, and the content malondialdehyde content was decreased by dichlormid, while the reduced glutathione content was increased by dichlormid significantly. …”
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1024
Hubungan Tumor Necrosis Factor-Alfa (Tnf-A) dengan Kadar Hemoglobin dan Parasitemia pada Infeksi Malaria Falciparum
Published 2014-05-01“…Kadar TNF-α dianalisis dengan metoda enzyme linked immunosorbent assay (ELISA).Hasil dari penelitian menunjukkan bahwa TNF-α dengan kadar hemoglobin (r = - 0,189, p > 0,05), TNF-α dengan parasitemia (r = 0,036, p > 0.05). …”
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1025
Effects of different microplastics on the physicochemical properties and microbial diversity of rice rhizosphere soil
Published 2025-01-01“…Microplastics also decreased soil enzyme activity, with aging-PLA having a somewhat stimulatory effect on enzyme activity compared to PLA. …”
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1026
Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase
Published 2025-02-01“…Furthermore, we determine that the Tae17 effector is a multidomain, bifunctional, peptidoglycan-degrading enzyme that has both amidase activity, which targets the sugar-peptide bonds, and lytic transglycosylase activity, which targets the peptidoglycan sugar backbone. …”
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1027
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases
Published 2025-01-01“…Phosphatidic acid phosphatase (PAP) is an evolutionarily conserved eukaryotic enzyme that catalyzes the Mg2+-dependent dephosphorylation of phosphatidic acid to produce diacylglycerol. …”
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1028
Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels of Clausena lansium L. Skeels
Published 2025-01-01“…Zeaxanthin was absent from both peels, suggesting that the b-carotene hydroxylase enzyme is not active. Both peels contain delphinidin-based (Dp) and cyanidin-based (Cy) anthocyanins, but not pelargonidin-based (Pg). …”
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1029
Practical techniques in molecular biotechnology /
Published 2021Table of Contents: “…Recombinant DNA and protein technology -- Enzyme kinetics, proteomics and mass spectrometry -- Bioanalytical techniques -- Molecular biology -- Cell culture -- Antibody technology.…”
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1030
The Role of System-Specific Molecular Chaperones in the Maturation of Molybdoenzymes in Bacteria
Published 2011-01-01“…This sulfur ligand is inserted into Moco while bound to the XdhC-like protein and before its insertion into the target enzyme. In addition, enzymes of the xanthine oxidase family bind either the molybdopterin (Mo-MPT) form of Moco or the modified molybdopterin cytosine dinucleotide cofactor (MCD). …”
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1031
Tissue Factor Structure and Function
Published 2012-01-01“…It is a component of the factor VIIa-TF complex enzyme and plays a primary role in both normal hemostasis and thrombosis. …”
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1032
Statins as Modulators of Regulatory T-Cell Biology
Published 2013-01-01“…Statins are pharmacological inhibitors of the activity of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR), an enzyme responsible for the synthesis of cholesterol. …”
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1033
Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature
Published 2012-01-01“…In our paper, we present a case of an acquired form of angioedema of the oropharyngeal region secondary to the simultaneous occurrence of two causative factors: neutralization of C1-inhibitor by an autoantibody and the use of an angiotensin convertin enzyme inhibitor.…”
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1034
DNA Polymerase e - More Than a Polymerase
Published 2003-01-01“…Together with DNA polymerases a and d, this enzyme replicates the nuclear DNA in the eukaryotic cell. …”
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1035
A Review of the GSTM1 Null Genotype Modifies the Association between Air Pollutant Exposure and Health Problems
Published 2023-01-01“…When the antioxidant enzyme function is lacking, ROS can accumulate and, thus, cause oxidative stress. …”
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1036
Study on the pathogenesis of pathophysiological changes of burn systemic infection
Published 1992-01-01“…Circulatory platelet aggregate ratio decreased significantly, while myocardiac enzyme spectrum greatly increased. Thrombi were observed in visceral tissues from patients dying of systemic infection. …”
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1037
Risk Factors for Hepatitis C Virus Transmission Obscure in Nigerian Patients
Published 2011-01-01“…They were also tested for anti-HCV using a third generation enzyme-linked immunosorbent assay. Result. The seroprevalence of anti-HCV was 4.7%. …”
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1038
VARIABILITY OF A FRAGMENT OF THE ACID VACUOLAR INVERTASE PAIN-1 GENE IN POTATO CULTIVARS
Published 2015-01-01“…Acid vacuolar invertase Pain-1 participates in the regulation of starch and sucrose contents in cells. This enzyme is also involved in plant response to abiotic stress. …”
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1039
Head and Neck Squamous Cell Carcinoma: NT5E Could Be a Prognostic Biomarker
Published 2022-01-01“…The hypoxia-adenosine pathway, in which CD73 encoded by the NT5E gene is a key enzyme for adenosine production, has been identified as an immune checkpoint of great potential. …”
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1040
Reversible Fetal Renal Impairment following Angiotensin Receptor Blocking Treatment during Third Trimester of Pregnancy: Case Report and Review of the Literature
Published 2016-01-01“…Late pregnancy usage of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) may cause severe oligohydramnios due to fetal renal impairment. …”
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