Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway by Mohammed M. Safhi, Mohammad Firoz Alam, Sivagurunathan Moni Sivakumar, Tarique Anwer

“…Exposure to the MESM tremendously modulated the levels of hepatic enzyme markers ALP, ACP, ALT, and AST in Groups 3 and 4. …”
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Effect of Sago Starch Concentration on Characteristic of Sago Glucose Syrup by Rissa Megavitry, Amran Laga, Adiansyah Syarifuddin

“…The use of sago substrate concentrations were 25%, 30%, and 35%. The use of amylase enzyme is 0.1% dry weight and glucoamylase enzyme is 0.008 g/g dry weight. …”
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DNA Polymerase: Structural Homology, Conformational Dynamics, and the Effects of Carcinogenic DNA Adducts by Richard G. Federley, Louis J. Romano

“…DNA replication is vital for an organism to proliferate and lying at the heart of this process is the enzyme DNA polymerase. Most DNA polymerases have a similar three dimensional fold, akin to a human right hand, despite differences in sequence homology. …”
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Case Report: Homozygous C677T MTHFR Gene Mutation in Male with Hypogonadism by Rami Salameh, Mumtaheena Miah, Catherine Anastasopoulou

“…Homozygous C677T individuals have decreased activity of MTHFR enzyme with increased homocysteine levels, which is associated with increased risk of thrombosis. …”
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Hyperglycemia in Streptozotocin-Induced Diabetes Leads to Persistent Inflammation and Tissue Damage Following Uveitis Due to Reduced Levels of Ciliary Body Heme Oxygenase-1 by Settimio Rossi, Michele D'Amico, Annalisa Capuano, Mary Romano, Pasquale Petronella, Clara Di Filippo

“…STZ-hyperglycemic rats had impaired levels of the enzyme HO-1 within the ciliary bodies if compared with the nondiabetic rats. …”
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Combined in Situ Zymography, Immunofluorescence, and Staining of Iron Oxide Particles in Paraffin-Embedded, Zinc-Fixed Tissue Sections by Eyk Schellenberger, Akvile Haeckel, Lena Schoenzart, Franziska Appler, Joerg Schnorr, Matthias Taupitz, Bernd Hamm

“…The combination of in situ zymography as well as IHC with subsequent Prussian blue iron staining on zinc-fixed paraffin-embedded tissues resulted in excellent histologic images of enzyme activity, protease distribution, and iron oxide particle accumulation. …”
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Renin-Angiotensin System Inhibitors in COVID-19: Current Concepts by Kunal Mahajan, Prakash Chand Negi, Neeraj Ganju, Sachin Sondhi, Naresh Gaur, Rao Somendra

“…The functional receptor to SARS-CoV-2, the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, is angiotensin-converting enzyme-2 (ACE-2), the same enzyme that physiologically counters the renin-angiotensin system (RAS) activation. …”
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Pain at chronic pancreatitis: origin and treatment options by V. T. Ivashkin, K. V. Ivashkin, A. V. Okhlobystin

“…Enzyme supplements at chronic pancreatitis can be indicated not only as replacement treatment, but also as addition to complex treatment of patients with severe abdominal pain. …”
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A combined use of Panax ginseng extract and the probiotic, Lactobacillus plantarum in the diet of Asian seabass, Lates calcarifer: Effects on growth, immunity and survival after ba... by Xiaojie Hou, Jianfeng Zhang, Neda Behmagham, Hamed Ghafarifarsani

“…In conclusion, fish supplemented with LAC-P and GINS, especially at 1 % level, showed significant improvements in growth, digestive enzyme activities, antioxidant enzyme levels, and immune responses. …”
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Combined analysis of 16S rRNA sequencing and metabolomics reveals the growth-promoting mechanism of compound probiotics in zig-zag eel (Mastacembelus armatus) by Yuwei Feng, Zhiting Zuo, Guangting Xie, Yiman Chen, Xiaoli Yin, Baoyue Lu, Zhide Yu, Chong Han, Hu Shu

“…The MIX probiotics can promote the activities of intestinal digestive enzymes and antioxidant enzymes by promoting the bacteria Brevundimonas, Bacillus, and Rhodococcus in the intestine. …”
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Production of an Extract with β-1,4-Xylanase Activity by <i>Fusarium oxysporum</i> f. sp. <i>melonis</i> on a Sonicated Brewer’s Spent Grain Substrate by Irma A. Arreola-Cruz, Rosalba Troncoso-Rojas, Francisco Vásquez-Lara, Nina G. Heredia-Sandoval, Alma R. Islas-Rubio

“…<i>F. oxysporum</i> grown on lignocellulosic substrates under submerged conditions produces an extracellular enzyme profile with hemicellulolytic and cellulolytic activities. …”
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Results of Selective Biochemical Screening for Lysosomal Acid Lipase Deficiency and Sequencing of the <i>LIPA</i> Gene in the Risk Group Patients by S. V. Shtykalova, A. A. Egorova, O. S. Glotov, A. V. Kiselev, I. Yu. Kogan

“…Biochemical study of the lysosomal acid lipase (LAL) enzyme activity was carried out according to Hamilton’s protocol of, using 4-methylumbelliferyl palmitate as a substrate and LAL inhibitor Lalistat-2. …”
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Engineering Soil Quality and Water Productivity Through Optimal Phosphogypsum Application Rates by Anrong Luo, Jun Li, Yanan Xiao, Zijian He, Jiaping Liang

“…Specifically, phosphogypsum enhanced yield through three pathways: (1) improving soil physical properties, which influenced soil nutrients and then improved enzyme activities; (2) directly affecting soil nutrients, which impacted enzyme activities and increased yield; and (3) directly boosting enzyme activities, leading to increased yield. …”
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Melatonin Enhances Maize Germination, Growth, and Salt Tolerance by Regulating Reactive Oxygen Species Accumulation and Antioxidant Systems by Wei-Qing Li, Jia-Yu Li, Shao-Jie Bi, Jia-Yue Jin, Zhong-Ling Fan, Zi-Lin Shang, Yi-Fei Zhang, Yan-Jie Wang

“…In addition, exogenous melatonin increased antioxidant enzyme activity and the expression of the antioxidant enzyme genes <i>ZmSOD4</i>, <i>ZmCAT2</i>, and <i>ZmAPX2</i>. …”
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PRMT5 Inhibitor EPZ015666 Decreases the Viability and Encystment of <i>Entamoeba invadens</i> by Rigoberto Ortiz-Hernández, Elmer Joel Millán-Casarrubias, Jeni Bolaños, Susana Munguía-Robledo, Carlos Vázquez-Calzada, Elisa Azuara-Licéaga, Jesús Valdés, Mario Alberto Rodríguez

“…In addition, we performed 3D modeling of this enzyme, as well as its molecular docking with the PRMT5 inhibitor EPZ015666, which predicted the affinity of the drug for the active site of the enzyme. …”
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Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferrets. by Natalia A Ilyushina, Jon P Seiler, Jerold E Rehg, Robert G Webster, Elena A Govorkova

“…We generated seven genetically stable recombinant clade 2.2 A/Turkey/15/06-like (H5N1) influenza viruses carrying NA mutations located either in the framework residues (E119A, H274Y, N294S) or in close proximity to the NA enzyme active site (V116A, I117V, K150N, Y252H). NA enzyme inhibition assays showed that NA mutations at positions 116, 117, 274, and 294 reduced susceptibility to oseltamivir carboxylate (IC(50)s increased 5- to 940-fold). …”
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Enhancing Royal grape quality through a three-year investigation of soil management practices and organic amendments on berry biochemistry by Ozkan Kaya, Sinem Karakus, Fadime Ates, Selda Daler, Harlene Hatterman-Valenti

“…Abstract Background Grape composition, characterized by mineral content, hormone levels, and antioxidant enzyme activities, fundamentally influences berry quality, nutritional value, and vine health. …”
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Tamarind Seed Xyloglucans Promote Proliferation and Migration of Human Skin Cells through Internalization via Stimulation of Proproliferative Signal Transduction Pathways by W. Nie, A. M. Deters

“…Both XGs improved keratinocytes and fibroblast proliferation, promoted the cell cycle, and stimulated migration and intracellular enzyme activity of NHDF after endosomal uptake. Only TSw significantly enhanced HaCaT migration and extracellular enzyme activity of NHDF and HaCaT. …”
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Hypertensive Crisis in Pregnancy with COVID19: Confirmed with rt-PCR for Nasopharyngeal Swab by Sajith Bandara, Anura Ruwanpathirana, Dhammika Nagodawithana, Samantha Alwis

“…SARS-CoV-2 enters and downregulates host cell-bounded enzyme ACE2 (angiotensin-converting enzyme). This activates the renin angiotensin aldosterone mechanism (RAAM). …”
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Isolation and Screening of Highly Cellulolytic Filamentous Fungi by Ibatsam Khokhar, Muhammad Saleem Haider, Sobia Mushtaq, Irum Mukhtar

“…A large number of microorganisms are capable of degrading cellulose, only a few of these microorganisms produce significant quantities of enzymes capable of completely hydrolysing cellulose. …”
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