Unveiling the Phytochemical Diversity and Bioactivity of <i>Astragalus melanophrurius</i>: A First Report Integrating Experimental and In Silico Approaches by Gulcan Gencer, Cengiz Sarikurkcu, Bektas Tepe

“…This study aimed to investigate the chemical profile, antioxidant capacity, and enzyme inhibitory activities of methanol extracts from various plant parts of <i>A. melanophrurius</i>. …”
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Flavocoxid, a Nutraceutical Approach to Blunt Inflammatory Conditions by Alessandra Bitto, Francesco Squadrito, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Anna Mecchio, Federica Galfo, Domenica Altavilla

“…Flavocoxid is a mixed extract containing baicalin and catechin and it acts as a dual balanced inhibitor of cyclooxygenase-1 (COX-1) and COX-2 peroxidase enzyme activities with a significant inhibition of 5-lipoxygenase (5-LOX) enzyme activity in vitro. …”
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Total Organic Carbon Analysis of Residual Contaminants in Bioreactor Equipment: A Cleaning Verification Study using Surface Swabbing by Ciara E. Fitzpatrick, James J. Roche

“…The high levels of organic contamination were attributed to the enzyme-active anionic detergent that was used during the cleaning procedure. …”
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Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament by Emmajay Sutherland, Christopher J. Harding, Tancrède du Monceau de Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster

“…Oxidations are often key to their biological activities, particularly C-C bond oxidation catalysed by tailoring enzymes including cyclodipeptide oxidases. These flavin-dependent enzymes are underexplored due to their intricate three-dimensional arrangement involving multiple copies of two distinct small subunits, and mechanistic details underlying substrate selection and catalysis are lacking. …”
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The Impact of Psoriasis and Metabolic Syndrome on the Systemic Inflammation and Oxidative Damage to Nucleic Acids by Drahomira Holmannova, Lenka Borska, Ctirad Andrys, Pavel Borsky, Jan Kremlacek, Kvetoslava Hamakova, Vit Rehacek, Andrea Malkova, Tereza Svadlakova, Vladimir Palicka, Jan Krejsek, Zdenek Fiala

“…Clinical examination (PASI score, MetS), enzyme-linked immunosorbent assay (ELISA), and Enzyme Immunoassay (EIA). …”
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Effect of dendritic cell vaccine on blood redox status in patients with cervical cancer by A. P. Menshenina, I. A. Goroshinskaya, E. M. Frantsiyants, T. I. Moiseenko, E. V. Verenikina, I. V. Kaplieva, L. A. Nemashkalova

“…The purpose of the study was to evaluate the dynamics of parameters of malondialdehyde (MDA), reduced glutathione and antioxidant enzyme activity in patients with advanced cervical cancer (CC) receiving anticancer treatment with dendritic cell vaccine (DCV).Patients and methods. …”
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Exploring the role of ubiquitination modifications in migraine headaches by Qian Zhu, Qian Zhu, Jin Yang, Jin Yang, Lei Shi, Lei Shi, Jieying Zhang, Jieying Zhang, Peng Zhang, Peng Zhang, Junlong Li, Junlong Li, Xiaoli Song, Xiaoli Song

“…The ubiquitin-proteasome system (UPS) is involved in neurological and inflammatory disorders. ubiquitination in the UPS is achieved through a cascade of enzymes, including Ub-activating enzyme (E1), Ub-coupling enzyme (E2), and Ub-ligase (E3). …”
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Correlation between MDA Level and Chitotriosidase-1 Activity in Seminal Fluid of Iraqi Infertile Males by Ali S. Abdul Aziz, Hedef D. Elyaseen, Hussain K. Kadhem

“…Chitotriosidase is a chitinase enzyme released by activated macrophages and is highly conserved and controlled. …”
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Serodiagnosis of ovine neosporosis in mosul city, iraq by Maab AL-Farwachi, Basima AL-Badrani, Wesam AL-Khafaji

“…<b>Aim:</b> The aim of this study was to determine the serodiagnosis of Neospora caninum by indirect enzyme linked immunosorbent assay (iELISA) among ewes in Mosul city.…”
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Anaesthetic Management of Two Patients with Pompe Disease for Caesarean Section by I. J. J. Dons-Sinke, M. Dirckx, G. P. Scoones

“…The introduction of enzyme replacement therapy and the resultant stabilisation or improvement in mobility and respiratory muscle function afforded to patients with late-onset Pompe may lead to an increased number of Pompe patients prepared to accept the challenges of parenthood. …”
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Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex by G. F. Korot'ko

“…To present experimental and clinical data on enzyme-ergic regulatory coupling of exocrine pancreatic secretion and evacuatory activity of gastroduodenal complex.Original positions. …”
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Laboratory Diagnosis of Chlamydia Pneumoniae Infections by Rosanna W Peeling

“…Antigen detection tests such as enzyme immunoassay and direct fluorescent antibody assay, and molecular detection methods such as the polymerase chain reaction assay, may provide a rapid diagnosis without the requirement for stringent transport conditions. …”
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Diarrhoea in Patients with COVID-19 by A. A. Sheptulin

“…The causes of diarrhoea may relate to the virus direct interaction with the angiotensin-converting enzyme 2 (ACE2) receptors in mucosa, its impact on the intestinal microbiota and therapeutic side effects. …”
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Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada by Shelley R Scriver, Canadian Antimicrobial Resistance Study Group, Donald E Low

“…Third-generation cephalosporin resistance was found to be as high as 29% in Enterobacter cloacae that possesses the Bush group 1 beta-lactamase and less than 4% in those isolates not possessing this enzyme. Cefepime equalled or exceeded the activity of the third-generation cephalosporins against the species of Enterobacteriaceae that demonstrated resistance to the third-generation cephalosporins.…”
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Pectinase from Microorganisms and Its Industrial Applications by Setegn Haile, Abate Ayele

“…Pectinase production faced various parameters optimization constraints such as temperature, pH and production times which are the main factors in pectinase production. The pectinase enzyme is getting attention due to its several advantages; hence, it needs to be explored further to take its maximum advantage in different industries. …”
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Liquorice Health Check, Oro-Dental Implications, and a Case Report by Louis Z. G. Touyz

“…Liquorice has an active substance, Glycyrrhizin which inhibits the conversion of precursor cortisol to cortisone by inhibiting the enzyme 11-betahydroxysteroid dehydrogenase. When imbibed, liquorice acts like hyperaldosteronism which presents with typical symptoms including high blood pressure, low blood potassium, and muscle pain and weakness. …”
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A Case of Chronic Pancreatic Insufficiency Due to Valproic Acid in a Child by Mary Anne Cooper, Aubrey Groll

“…The patient eventually developed steatorrhea and weight loss that improved with pancreatic enzyme replacement. Radiological evaluation showed an atrophic pancreas. …”
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Myeloid ACAT1/SOAT1: a novel regulator of dyslipidemia and retinal neovascularization by Syed A. H. Zaidi, Ruth B. Caldwell, Modesto A. Rojas

“…We show that OIR-induced activation of macrophage/microglial cells, retinal inflammation, and pathological RNV are mediated by increases in cholesterol ester (CE) formation due to activation of the acyl-CoA: Cholesterol Acyltransferase 1/Sterol O-Acyltransferase 1 (ACAT1/SOAT1) enzyme.…”
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Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster by Johnmark, Ndinawe, Hellen, W. Kinyi

“…The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H2O2 induced oxidative stress in Drosophila melanogaster flies was assessed. …”
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Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress... by Ágnes Szabó, Zsolt Galla, Eleonóra Spekker, Mónika Szűcs, Diána Martos, Keiko Takeda, Kinuyo Ozaki, Hiromi Inoue, Sayo Yamamoto, József Toldi, Etsuro Ono, László Vécsei, Masaru Tanaka

“…Little is known about the consequences of deleting the KYN enzyme gene. …”
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