Nutritional support in early phases of acute pancreatitis: fashionable trend and essential reality by Ye. Ye. Achkasov, A. V. Pugayev, G. V. Dyatchina, V. I. Posudnevsky, Zh. G. Nabiyeva, P. V. Melnikov

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USE OF RAPID METHODS FOR TESTING MEAT, VISCERA AND ANIMAL PRODUCTS by A. V. Tyunev, M. V. Alekseyeva

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Discovery of novel biphenyl compounds bearing hydroxamic acid moiety as the first PD-L1/class I HDACs dual inhibitors by Dandan Yuan, Yali Gao, Lin Xia, Han Liu, Xingye Wu, Xueyan Ding, Yudan Huang, Changchun Deng, Jin Li, Wenqi Dai, Jieqing Liu, Junjie Ma

“…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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Exploring covalent inhibitors of SARS-CoV-2 main protease: from peptidomimetics to novel scaffolds by Noor Atatreh, Radwa E. Mahgoub, Mohammad A. Ghattas

“…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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Small molecules targeting the eubacterial β-sliding clamp discovered by combined in silico and in vitro screening approaches by Alessia Caputo, Gian Marco Elisi, Elisabetta Levati, Giulia Barotti, Sara Sartini, Jerome Wagner, Dominique Y. Burnouf, Simone Ottonello, Silvia Rivara, Barbara Montanini

“…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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Indirubin-3′-oxime as a dual-action agent: mitigating heat-induced male infertility in Drosophila melanogaster and inhibiting soluble epoxide hydrolase by Nguyen Viet Phong, Hyo-Sung Kim, Yan Zhao, Eunbyul Yeom, Seo Young Yang

“…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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The new thiazolidine-2,4-dione-based hybrids with promising antimycobacterial activity: design, synthesis, biological evaluation, and drug interaction analysis by Nazar Trotsko, Agnieszka Głogowska, Barbara Kaproń, Katarzyna Kozieł, Ewa Augustynowicz-Kopeć, Agata Paneth

“…Journal of Enzyme Inhibition and Medicinal Chemistry…”
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Polyethylenimine-Assisted Aggregation of β-Galactosidase from Kluyveromyces lactis by Nedim Albayrak, Rabia Akyol Kütük

“…The PEI aggregation of enzyme led to enhancements in chemical and physical characteristics compered to free enzyme. …”
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Design of the Inhibitors for Pseudorabies Virus Replication by Reinforcement Learning from HSV‑1 DNA Polymerase Inhibitors by Lin Wei, Yang Hu, Licheng Bai, Chenxu Xiao, Zhang Liu, Yun You, Keke Wang, Yunyuan Huang, Junfei Zhu, Jun Weng, Wenling Zhou, Han Li, Honghe Zhao, Zhiyong Wu, Meng Mei, Zigong Wei

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Recycling agroâindustrial waste to produce amylase and characterizing amylaseâgold nanoparticle composite by Aditya Mojumdar, Jashmini Deka

“…Purpose Amylase being one of the most important industrial enzymes requires large-scale production. When producing an enzyme, high productivity, high purity and low production costs need to be considered. …”
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Carboxylated nanocellulose from quinoa husk for enhanced protease immobilization and stability of protease in biotechnological applications by Shohreh Ariaeenejad, Elaheh Motamedi

“…The immobilization efficiency, activity, stability, kinetic parameters, and reusability of covalently attached and physically immobilized PersiProtease1 were similar to those of the free enzyme. Enzyme immobilization resulted in higher thermal stability of the enzyme at elevated temperatures (> 80 °C), and the covalently immobilized enzyme displayed higher reusability than its physically immobilized form (56% vs. 37% activity, after 15 consecutive cycles), which would be rooted in a more tightly attached and less leached enzyme in the case of PersiProtease1/DCNCs. …”
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Ammonia-Assimilating Bacteria Promote Wheat (<i>Triticum aestivum</i>) Growth and Nitrogen Utilization by Yuqian Gao, Qi Zhang, Yuannan Chen, Yanqing Yang, Chenxiao Zhou, Jiayang Yu, Yanan Li, Liyou Qiu

“…However, root GS, GOGAT enzyme activities, and ammonia assimilation-related gene expressions were lower than the controls. …”
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Purification and characterization of arginine deiminase from Klebsiella pneumoniae by Taif Hussien Alameedy, Mohammed Abdullah Jebor

“…Results: After 5.9 folds of purification and 38.7% enzyme recovery, the specific activity of the purified enzyme reached 164.2 U/mg. …”
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The Stability Improvement of Aspergillus fumigatus α-Amylase by Immobilization onto Chitin-Bentonite Hybrid by Ezra Rheinsky Tiarsa, Yandri Yandri, Tati Suhartati, Heri Satria, Bambang Irawan, Sutopo Hadi

“…Enzyme immobilization is a powerful method to improve the stability, reuse, and enzymatic properties of enzymes. …”
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Molecular insights into a distinct class of terpenoid cyclases by Siyu Li, Jian-Wen Huang, Jian Min, Hao Li, Meidan Ning, Shuyu Zhou, Yu Yang, Chun-Chi Chen, Rey-Ting Guo

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Partial Purification and Characterization of Rhodanese from Rainbow Trout (Oncorhynchus mykiss) Liver by Hossein Tayefi-Nasrabadi, Reza Rahmani

“…Rhodanese, a ubiquitous enzyme, can catalyse the detoxification of cyanide by sulphuration reaction. …”
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Production and Characterization of Highly Thermostable β-Glucosidase during the Biodegradation of Methyl Cellulose by Fusarium oxysporum by Folasade M. Olajuyigbe, Chidinma M. Nlekerem, Olusola A. Ogunyewo

“…Optimized production of β-glucosidase using the cellulosic substrate that supported highest yield of enzyme was examined over 192 h fermentation period and varied pH of 3.0–11.0. …”
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Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver by Misako Taniguchi, Nobuko Mori, Chizuru Iramina, Akira Yasutake

“…Weanling male Wistar rats were fed on a 10% soybean protein isolate (SPI) diet for 3 weeks with or without supplementing 0.3% sulfur-containing amino acids (SAA; methionine or cystine) to examine relationship between glutathione (GSH) levels and activities of NADPH-producing enzymes, glucose 6-phosphate dehydrogenase (G6PD) and malic enzyme (ME), in the liver. …”
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A Novel Process to Prepare Chitosan Macrospheres without Shrinkage and its Application to Immobilize β-Galactosidase by Su-Fang Sun, Yan Zhang

“…A new process for the preparation of chitosan macrospheres, which was simple and practicable, was suggested in this paper and various chitosans with different molecular weight were used as materials to immobilize β-galactosidase and the chitosan macrospheres with the lowest molecular weight (500 000) was selected as enzyme immobilization carrier based on the highest enzyme activity. …”
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Safety assessment of a novel marine multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 according to phenotype and whole genome-sequencing analysis by Xueyan Mo, Mengcheng Zhou, Yanmei Li, Lili Yu, Huashang Bai, Peihong Shen, Xing Zhou, Haojun Zhu, Huijie Sun, Ru Bu, Chengjian Jiang

“…GXDK6 had no resistance to common antifungal drugs. Virulence enzymes, such as gelatinase, DNase, hemolytic, lecithinase, and thrombin were absent. …”
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