Identification of Flavonoid C-Glycosides as Promising Antidiabetics Targeting Protein Tyrosine Phosphatase 1B by Athika Rampadarath, Fatai Oladunni Balogun, Charlene Pillay, Saheed Sabiu

“…Of the seven flavonoid C-glycosides docked against the enzyme, three compounds (apigenin, vitexin, and orientin) had the best affinity for the enzyme with a binding score of –7.3 kcal/mol each, relative to –7.4 kcal/mol for the reference standard, ursolic acid. …”
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METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway by Jinghua Wang, Shushan Yan, Hongying Lu, Shufeng Wang, Donghua Xu

“…Methyltransferase-like 3 (METTL3), an RNA N6-methyladenosine (m6A) methyltransferase, is essential for the m6A mRNA modification. As a key enzyme of m6A methylation modification, METTL3 has been implicated in immune and inflammation regulation. …”
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Fish protein fertilizer serves as a sustainable alternative, improving soil properties, bamboo growth and shoots yield in Lei bamboo forests by Jiancheng Zhao, Huijing Ni, Bo Wang, Zhenya Yang

“…Overall, amino acid fertilizer can promote microbial growth through supplying carbon sources and nitrogen sources, enhance soil enzyme activity, thus promote phosphorus activation and increase soil phosphorus effectiveness, and then expand the scale of root foraging and ultimately improve nutrients absorption and increase bamboo shoot yield.…”
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Purification, Characterization, and Biocatalytic and Antibiofilm Activity of a Novel Dextranase from Talaromyces sp. by Mahasen Mohamed Ahmed Ebaya, Mohammed El-Mowafy, Mohamed Mohamed Adel El-Sokkary, Ramadan Hassan

“…Dextranase is a useful enzyme that catalyzes the degradation of dextran to low-molecular-weight fractions, which have many critical commercial and clinical applications. …”
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Nonalcoholic Fatty Liver Disease in Canadian First Nations and Non-First Nations Patients by Julia Uhanova, Gerald Minuk, Federico Lopez Ficher, Natasha Chandok

“…There were no significant differences in liver enzyme or function tests in either cohort after approximately three years of follow-up. …”
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Reduced Expression of Voltage-Gated Sodium Channel Beta 2 Restores Neuronal Injury and Improves Cognitive Dysfunction Induced by Aβ1-42 by Shan Li, Guo-Ji Yan, Ya-Xin Tan, Lu-Lu Xue, Ting-Hua Wang, Hao-Ran Zhao, Min-Nan Lu, Hui-Xiang Zhang, Rong Mei, Xiao-Han Dong, Li-Na Liu, Dan Wang, Yan-Bin Xiyang

“…The results showed that Navβ2 knockdown restored neuronal viability of Aβ1-42-induced injury in neurons; increased the contents of brain-derived neurotrophic factor (BDNF), enzyme neprilysin (NEP) protein, and NEP enzyme activity; and effectively altered the proportions of the amyloid precursor protein (APP) metabolites including Aβ42, sAPPα, and sAPPβ, thus ameliorating cognitive dysfunction. …”
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Biomarker response of climate change-induced ocean acidification and hypercapnia studies on brachyurian crab Portunus pelagicus by R. Jeevapriya, M. Anand, M. Maruthupandy, A. Hameedha Beevi

“…Levels of the antioxidant enzyme catalase, the phase II detoxification enzyme, glutathione S. transferase, the lipid peroxidation biomarker, malondialdehyde, acetylcholinesterase, and reduced glutathione were estimated in the tissues of the exposed animals to validate theses enzymes as biomarkers of Hypercapnia. …”
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Supplementing the Diet of Hybrid Grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) with Compound Acidifier Is a Good Way to Alleviate Poor Intestinal Growth Caused by High L... by Jiacheng Zhang, Hongjin Deng, Weixing Liang, Shuyan Chi, Beiping Tan, Xiaohui Dong, Shuang Zhang

“…In conclusion, when the hybrid grouper was given a diet containing more CPC, the FCA0.05 group was able to promote intestinal development, enhance digestive enzyme activity and feed consumption, raise antioxidant enzyme activity and anti-inflammatory factor expression, and improve intestinal health.…”
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Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer’s Disease Treatment: An In Vitro Study by Nermeen El-Moataz Bellah Ahmed, Masashi Murakami, Yujiro Hirose, Misako Nakashima

“…Furthermore, neprilysin enzyme was detected in DPSC secretome and succeeded in degrading Aβ1–42 in vitro in 12 hours. …”
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A Novel Nitrite Reductase from <i>Acinetobacter haemolyticus</i> for Efficient Degradation of Nitrite by Xiao-Yan Yin, Emmanuel Mintah Bonku, Jian-Feng Yuan, Zhong-Hua Yang

“…We constructed a heterologous expression system using <i>E. coli</i> BL21/pET28a-<i>Ah</i>Nir, which exhibited remarkable nitrite reductase enzyme activity of 29 U/mL in the culture broth, substantially higher than that reported for other strains. …”
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Evaluating the effects of hand weeding and selective herbicides on weeds control and maize (Zea mays L.) traits by Fakhari Rasoul, Moharramnejad Sajjad, Didehbaz Moghanlo Ghorban, Mammadova Ruhangiz

“…Also, increasing the dose of Amaize-ing increased the proline content and activity of catalase enzyme in maize.…”
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Associations between skeletal muscle phenotype, positional role, and on‐ice performance in elite male ice hockey players by Jeppe F. Vigh‐Larsen, Hallur Thorsteinsson, Martin Thomassen, Jeppe Panduro, Bjørn Fristrup, Morten B. Randers, Jens L. Olesen, Peter Krustrup, Kristian Overgaard, Lars Nybo, Magni Mohr

“…Resting thigh muscle biopsies were analyzed for metabolic enzyme activity and protein expression linked to performance. …”
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Effectiveness of the PSI BLAST algorithm in dependence on scanning word size by Mindaugas Margelevičius, Albertas Timinskas

“…We also accomplish statistical analysis for each enzyme of the cytosine-5 methyltransferase family after we apply alignment searching for the biologically related protein sequences. …”
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Cellulase hydrolyzed Indigofera zolingeriana leaf utilization as a feed ingredient for gourami fingerling by Jefry Jefry, Mia Setiawati, Dedi Jusadi, Ichsan Achmad Fauzi

“…The first step performed by evaluating the Indigofera leaf meal (ILM) added with cellulase enzyme of 0 g/kg (control), 0.4 g/kg, 0.8 g/kg, and 1.2 g/kg. …”
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The antiarthritic effect of CBR‐470‐1 in hypoxic environment is to increase the level of NOD‐like receptor family pyrin domain containing 3 ubiquitination by decreasing phosphoglyc... by Ao Duan, Zemeng Ma, Xiaolong Shao, Zhencheng Xiong, Chaoyi Zhang, Wenzheng Liu, Guanglin Wang, Shouye Hu, Wei Lin

“…Hypoxia plays a pro‐inflammatory role by increasing PGK1 activity, reducing the binding of the deubiquitinating enzyme USP14 to NLRP3, and reducing the ubiquitination level of NLRP3. …”
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Autophagy protein Atg7 is essential for maintaining malaria parasite cellular homeostasis and organelle biogenesis by Akancha Mishra, Suryansh Rajput, Pratik Narain Srivastava, H. Shabeer Ali, Satish Mishra

“…Here, we report that an autophagy-related E1-like enzyme Atg7 is required to conjugate Atg8 on the apicoplast membrane. …”
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Strenuous Exercise-Induced Tremendously Elevated Transaminases Levels in a Healthy Adult: A Diagnostic Dilemma by Prabin Khatri, Aryan Neupane, Suman Raj Sapkota, Bibhav Bashyal, Dipesh Sharma, Ashmita Chhetri, K. C. Chirag, Ashish Banjade, Priyanka Sapkota, Subarna. Bhandari

“…The liver function test (LFT) is a commonly performed test in clinical practice in order to assess well-being of the liver; however, derangement in liver enzymes, however, may not necessarily imply an underlying liver pathology. …”
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Synthesis of Galactosyl Mannitol Derivative Using β-Galactosidase from Kluyveromyces lactis by Klewicki Robert, Belina Iwona, Wojciechowska Aleksandra, Klewicka Elżbieta, Sójka Michał

“…The use of the enzyme dose ranging from 2850 to 11,400 LAU/100 g lactose allowed obtaining gal-mannitol at the level of 21.8% total saccharides; higher doses intensified product decomposition. …”
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Tacrolimus toxicity management in a pregnant kidney transplant recipient with newly diagnosed human immunodeficiency virus: A case report by Ahmad Matarneh, Ravi chokshi, Sundus Sardar, Dinia Salmeron, James O’brien, Fareeha Khalil, Naman Trivedi, Nasrollah Ghahramani, Vaqar Shah

“…Tacrolimus toxicity is often managed by administering cytochrome P450 enzyme inducers, with the choice of agent depending on factors such as the degree of enzyme induction. …”
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Arginase Inhibitor in the Pharmacological Correction of Endothelial Dysfunction by Mihail V. Pokrovskiy, Mihail V. Korokin, Svetlana A. Tsepeleva, Tatyana G. Pokrovskaya, Vladimir V. Gureev, Elena A. Konovalova, Oleg S. Gudyrev, Vladimir I. Kochkarov, Liliya V. Korokina, Eleonora N. Dudina, Anna V. Babko, Elena G. Terehova

“…Because of the high activity of arginase enzyme which catalyzes the hydrolysis of L-arginine into ornithine and urea, the bioavailability of nitrogen oxide decreases. …”
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