Rational design, synthesis, in vitro, and in-silico studies of pyrazole‑phthalazine hybrids as new α‑glucosidase inhibitors by Mehrdad Roshan, Roghieh Mirzazadeh, Azadeh Tajmir-Riahi, Mohammad Sadegh Asgari

“…Abstract This paper describes the design, development, synthesis, in silico, and in vitro evaluation of fourteen novel heterocycle hybrids as inhibitors of the α-glucosidase enzyme. The primary aim of this study was to explore the potential of novel pyrazole-phthalazine hybrids as selective inhibitors of α-glucosidase, an enzyme involved in carbohydrate metabolism, which plays a key role in the management of type 2 diabetes. …”
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Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes by M. S. H. Al-Furjan, Kui Cheng, Wenjian Weng

“…TiO2 has a good protein adsorption ability and facilitates having more enzyme adsorption and better electron transfer. In this work, Mg ions are introduced into TiO2 nanodots in order to further improve electrode performance because Mg ions are considered to have good affinity with proteins or enzymes. …”
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Immobilization of Laccase in Alginate-Gelatin Mixed Gel and Decolorization of Synthetic Dyes by Mehdi Mogharabi, Nasser Nassiri-Koopaei, Maryam Bozorgi-Koushalshahi, Nastaran Nafissi-Varcheh, Ghodsieh Bagherzadeh, Mohammad Ali Faramarzi

“…The obtained data showed that both immobilized and free enzymes acted optimally at 50°C for removal of crystal violet, but the entrapped enzyme showed higher thermal stability compared to the free enzyme. …”
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An Assay System for Plate-based Detection of Endogenous Peptide:N-glycanase/NGLY1 Activity Using A Fluorescence-based Probe by Hiroto Hirayama, Tadashi Suzuki

“…This enzyme also plays a role in the quality control system for nascent glycoproteins. …”
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Isolation, Purification, and Characterization of Xylanase Produced by a New Species of Bacillus in Solid State Fermentation by Rajashri D. Kamble, Anandrao R. Jadhav

“…For birchwood xylan, the enzyme gave a Km 5.26 ;mg/mL and Vmax 277.7 ;μmol/min/mg, respectively. …”
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Cassava Starch as an Effective Texture Corrector of Fat-Free Dairy Products Based on Symbiotic Starter Culture by Maxim S. Tsyganov, Galina O. Ezhkova, Maya A. Kharitonova, Elena V. Nikitina

“…A possible solution to this problem can be the use of partially hydrolyzed cassava starch; complex microbial amylase preparations, for instance, Amylosubtilin® or Bacillus licheniformis amylases, can be used as an enzyme. The use of these enzyme preparations in low concentration allows it to obtain cassava starches with increased solubility, which can be easily used in the technology of dairy products. …”
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Purification and characterization of lipase from Bacillus subtilis kubt4 for biodiesel production by Parveen Nadaf, Shridhar Ghagane, Rubeen Dadakalandar Nadaf, Shivasharana Chandrabanda Timmappa

“…The presence of Mg2+ ions significantly enhanced the enzyme activity by 180.21%. Kinetic analysis revealed Vmax and Km values for pNP palmitate of 8.33 M and 1.025 μM/min, respectively. …”
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Differential Effects of Alcoholic and Non-Alcoholic Beer Intake on Renin–Angiotensin System Modulation in Spontaneous Hypertensive Rats by María Dolores Mayas, Cristina Cueto-Ureña, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos

“…AB consumption increased liver enzyme activity. Significant changes were observed in the RAS enzyme activity across tissues, varying by strain, beer type, and tissue. …”
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Screening of a Soil Tyrosianse Producing Bacterial Strain HM24 and Comparison of its Tyrosinase Activity in Different Mediums Containing Natural Sources of L-tyrosine by Seyed Muhammad Hamid Malekpour, Moj Khaleghi, Alireza Akhtarpour

“…Tyrosinases are essential enzymes with diverse applications, such as breaking down phenolic compounds and producing melanin. …”
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Seasonal Pattern of Endo-β-Mannanase Activity During Germination of <i>Jeffersonia dubia</i>, Exhibiting Morphophysiological Dormancy by Young Hyun Kwon, Seung Youn Lee, Yong Ha Rhie

“…During the winter months, embryo elongation ceased for 2–3 months, and enzyme activity declined. However, as germination resumed in early March, enzyme activity increased again. …”
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Salicylic Acid Improved the Growth of <i>Dunaliella salina</i> and Increased the Proportion of <i>9-cis</i>-β-Carotene Isomers by Shuaicheng Xiang, Xiaoting Qiu, Xiaojun Yan, Roger Ruan, Pengfei Cheng

“…In this study, the effects of SA on the growth, biochemical composition, antioxidant enzyme activity, key enzymes of β-carotene synthesis, and cis-and trans-isomers of β-carotene in <i>D. salina</i> under different salt concentrations were investigated. …”
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Characteristic of pH and Temperature of Crude Extract of Glukoamilase from Gliocladium KE by using Solid Substrate of Sago Hampas by Risa Meutia Fiana, Novelina Novelina, Alfi Asben

“… This  research  wasaimed  at  figuring  optimumpH and  temperature  of crude  enzyme  extract glukoamilase from  isolate Gliocladium  KEusing  substrate  of  solid  sago  hampas. …”
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Immobilization of Isolated Lipase From Moldy Copra (Aspergillus Oryzae) by Seniwati Dali, A. B. D. Rauf Patong, M. Noor Jalaluddin, Pirman, Baharuddin Hamzah

“…Enzyme immobilization is a recovery technique that has been studied in several years, using support as a media to help enzyme dissolutions to the reaction substrate. …”
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11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia by Katarzyna Kosicka, Anna Siemiątkowska, Franciszek K. Główka

“…The reduced activity of the enzyme was observed in placentas from pregnancies complicated with preeclampsia. …”
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Modulation of nitric oxide synthase activity in macrophages by P. G. Jorens, K. E. Matthys, H. Bult

“…Activated rodent macrophages are capable of expressing an inducible form of this enzyme (iNOS) in response to appropriate stimuli, i.e., lipopolysaccharide (LPS) and interferon-γ (IFNγ). …”
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Immobilization of Purified Pectin Lyase from Acinetobacter calcoaceticus onto Magnetic Carboxymethyl Cellulose Nanoparticles and Its Usability in Food Industry by Esen Tasgin, Aynur Babagil, Hayrunnisa Nadaroglu

“…An important component of the pectinase enzyme complex is pectin lyase (polymethylgalacturonate lyase; EC 4.2.2.10). …”
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Phytase Production by Aspergillus niger CFR 335 and Aspergillus ficuum SGA 01 through Submerged and Solid-State Fermentation by Gunashree B. Shivanna, Govindarajulu Venkateswaran

“…Aspergillus niger CFR 335 and A. ficuum produced a maximum of 60.6 U/gds and 38 U/gds of the enzyme, respectively, in wheat bran solid substrate medium. …”
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Xylanase-Producing Microbes and Their Real-World Application by Milan Phuyal, Uttam Budhathoki, Durga Bista, Shailendra Shakya, Rajan Shrestha, Ashwinee Kumar Shrestha

“…The present study is focused on the availability of microbial sources capable of producing xylanase, a hemicelluloses-degrading enzyme with multiple modes of action along with specificity, and their real-world applications. …”
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End-Group Evaluation of HEMA Initiated Poly(ε-caprolactone) Macromonomers via Enzymatic Ring-Opening Polymerization by N. Ugur Kaya, Y. Avcibasi Guvenilir

“…The side reactions generated due to the cleavage of ester bonds in HEMA and the growing polymer chains were investigated through altering polymerization period, initiator concentration, temperature, and enzyme concentration. 1H NMR evaluations showed that minimum quantities of side reactions were in lower temperatures, initiator concentration, enzyme concentration, and lower monomer conversions. …”
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Discovering broad-spectrum inhibitors for SARS-CoV-2 variants: a cheminformatics and biophysical approach targeting the main protease by Safar M. Alqahtani

“…The simulations showed a stable structure of the main protease enzyme with the shortlisted leads in the pocket, and the network of binding interactions remained intact during the simulations. …”
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