Anti-arthritic potential of crude sulfated polysaccharide from marine macroalgae Sargassum ilicifolium (Turner) C. Agardh: Regulation of cytokine cascade by Ramamoorthi Lavanya, Jeyabalan Srikanth, Sankar Seethalakshmi, Begum M. Yasmin, Duraipandian Chamundeeswari, Sekar Mahendran, Wong Ling Shing, Subramaniyan Vetriselvan

“…Methotrexate and CSP treatment dramatically decreased the levels of the investigated marker enzymes. Histopathology revealed that low-dose CSP (5 mg/kg, p.o.) significantly reduced the severity of synovitis, panniculitis, liver necrosis, inflammatory cell infiltration, and cortical and paracortical necrotic foci in node, compared to the high dose (10 mg/kg, p.o.). …”
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The Regulatory Effect of Se-Cd Interaction on Tea Plants (<i>Camellia sinensis</i> (L.) O. Kuntze) Under Cadmium Stress by Yanyun Sun, Yueling Zhao, Hongyu Zhou, Faxing Li, Yuanyuan Wang, Xiao Du

“…The findings are as follows: (1) Cd stress notably elevated the electrical conductivity, MDA content, and proline content of tea plants, whereas the Cd + Se₁ treatment significantly reduced the MDA and proline content under Cd stress; (2) the Cd stress treatment significantly increased the content of peroxides in the tea tree leaves and significantly decreased the activities of four antioxidant enzymes, SOD, POD, CAT, and Apx; the Cd + Se treatment significantly reduced the peroxide content in tea trees under cadmium stress and significantly increased the activities of SOD, POD, CAT, and Apx; (3) the Cd stress treatment significantly increased the values of certain chlorophyll fluorescence parameters and had no significant impact on the distribution of light energy, whereas the Cd + Se treatment significantly elevated the values of some chlorophyll fluorescence parameters and induced an uneven distribution of light energy; (4) the order of accumulation of Cd in different organs of the tea plants was as follows: root > stem > leaf, and the Cd + Se treatment significantly reduced the Cd content in various organs under Cd stress. …”
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Allelic variants for Waxy genes in common wheat lines bred at the Lukyanenko National Grain Center by E. R. Davoyan, L. A. Bespalova, R. O. Davoyan, E. V. Agaeva, G. I. Bukreeva, Yu. S. Zubanova, D. S. Mikov, D. M. Boldakov

“…The study was carried out as part of the work on the transfer of null alleles of the genes Wx-A1, Wx-B1, and Wx-D1 to the varieties of soft wheat and creation of breeding material with modified activities of the main enzymes involved in amylose biosynthesis. The lines were obtained at the Department of Breeding and Seed Production of Wheat and Triticale, National Center of Grain named after P.P. …”
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Carbapenem-resistant Enterobacterales (CRE) colonisation as a predictor for subsequent CRE infection: A retrospective surveillance study by Courtney M. Tubb, Marco Tubb, Jonathan Hooijer, Rispah Chomba, Jeremy Nel

“…Results: The prevalence of CRE colonisation was 12.4% (95% confidence interval [CI]: 10.1–15.1), with Klebsiella pneumoniae (81.2%) being the most common CRE isolated and OXA-48-like enzymes (94.5%) being the most frequent carbapenemase detected. …”
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Comparison of thromboelastographic profiles and clinical characteristics in children with severe Mycoplasma pneumoniae pneumonia by Yong-tao Li, Yu-mei Ma, Fu-li Dai, Zhen Peng, Ya-ping Dai, Ke Zhi, Hai-hong Feng, Shu-jun Li

“…The abnormal TEG group had higher incidences of coagulopathy (P &lt; 0.001), cardiac involvement (elevated cardiac enzymes: 36.8% vs. 17.1%, P = 0.009; pericardial effusion: 10.5% vs. 1.3%, P = 0.017), and plastic bronchitis (P = 0.006). …”
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In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways by Khalid Saad Alharbi, Muhammad Afzal, Fahad A. Al-Abbasi, Ehssan Moglad, Salwa D. Al-Qahtani, Naif A. R. Almalki, Faisal Imam, Nadeem Sayyed, Imran Kazmi

“…It improved serum insulin, blood lipid profile and reduced inflammatory cytokines (IL-6, TNF-α, IL-β), oxidative stress and increased antioxidant enzymes (SOD, CAT and GSH). Europinidin also protected renal, hepatic functions and restored apoptosis markers (increased Bcl-2, decreased caspase-3 levels). …”
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Reproducibility and Consistency of Isolation Protocols for Fibroblasts, Smooth Muscle Cells, and Epithelial Cells from the Human Vagina by Jayson Sueters, Rogier Schipperheijn, Judith Huirne, Theo Smit, Zeliha Guler

“…Protocols were derived from published reports on cell isolation by enzymes, with exclusion criteria including the need for specialized equipment, surgical separation of tissue layers, or missing protocol details. …”
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Integrative application of licorice root extract and melatonin improves faba bean growth and production in Cd-contaminated saline soil by Shimaa A. Abd El Mageed, Ali A. S. Sayed, Ahmed Shaaban, Khaulood A. Hemida, Abdelsattar Abdelkhalik, Wael M. Semida, Ibrahim A. A. Mohamed, Mohammed A. H. Gyushi, Yasmine H. Abd Elmohsen, Taia A. Abd El Mageed

“…Application of LRE + Mt significantly mitigated the Cd-induced oxidative damage by increasing the activity of reactive oxygen species (ROS) scavenging enzymes such as superoxide dismutase, catalase, ascorbate peroxidase, and glutathione reductase, in parallel with enhanced ascorbate and reducing glutathione content. …”
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The application of biochar and organic fertilizer substitution regulates the diversities of habitat specialist bacterial communities within soil aggregates in proso millet farmland by Lixin Tian, Yawei Wang, Doudou Jin, Yulong Zhou, Bauyrzhan Mukhamed, Dan Liu, Baili Feng

“…OF + B treatment also markedly elevated the contents of total nitrogen (TN), soil organic carbon (SOC), nitrate nitrogen (NO3 −-N), ammonium nitrogen (NH4 +-N), as well as activities of C-, N-, and P-acquiring enzymes, enhanced the carbon limitation, and reduced the nitrogen limitation in the bulk soil and macro-aggregates. …”
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Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample by Catherine Prattico, Emmanuel Gonzalez, Lharbi Dridi, Shiva Jazestani, Kristin E. Low, D. Wade Abbott, Corinne F. Maurice, Bastien Castagner

“…The short incubation was sufficient to cause induction of genes involved in carbohydrate metabolism, like carbohydrate-active enzymes (CAZymes), including glycoside hydrolase family 32 genes, which hydrolyze fructan polysaccharides like FOS and inulin. …”
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Mechanism of sodium nitroprusside regulating ginseng quality by Wei Zhang, Pengcheng Yu, Wenfei Liu, Liyang Wang, Xiaowen Song, Yao Yao, Xiubo Liu, Xiangcai Meng

“…The main root treated by 0.5 mmol/L SNP for three days was the best, with the activities of the key enzymes of the ginsenoside synthesis pathway, 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR), farnesyl pyrophosphate synthase (FPS), squalene synthase (SS), squalene epoxidase (SE), and dammarane diol-II synthase (DS) activities increased markedly; the ginsenosides Rg1 + Re, Rb1, Rf, Rc, Rg2 + Rh1 and the total ginsenoside contents increased by 51.0%, 77.7%, 44.6%, 26.8%, 63.2% and 48.2%, respectively, but only a trace amount of the ginsenoside monomer Rb2 decreased 23.4%. …”
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Optimization of industrial symbiosis in coffee-based eco-industrial park design by N. Laili, T. Djatna, N.S. Indrasti, M. Yani

“…The application of the mixed-integer linear programming optimization model has provided a structured approach to maximizing the value creation within the eco-industrial park through the valorization of 72.3 percent of coffee pulp and 68.5 percent of spent coffee grounds into cellulase enzymes and ultraviolet shields.CONCLUSION: This paper presents a structured framework for efficiently managing material exchange processes within an eco-industrial park, contributing to environmental sustainability and economic value creation. …”
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Hubungan Konsumsi Serat dengan Pola Defekasi pada Mahasiswi Fakultas Kedokteran Unand Angkatan 2012 by Indah Paradifa Sari, Arina Widya Murni, Masrul .

“…</em><em>Dietary fiber</em><em> is defined as carbohydrates that are resistant to hydrolysis enzymes in human digestive. Based on data RISKESDAS 2013, West Sumatra ranks third lowest fiber intake across Indonesian provinces</em><em>. …”
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Trade-Off Between Enzymatic Antioxidant Defense and Accumulation of Organic Metabolite Affects Salt Tolerance of White Clover Associated with Redox, Water, and Metabolic Homeostase... by Min Zhou, Yuting Wu, Yuchen Yang, Yan Yuan, Junnan Lin, Long Lin, Zhou Li

“…These findings indicated a trade-off relationship between antioxidant enzymes and nonenzymatic antioxidants in different white clover genotypes adapting to salt stress. …”
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Microbial-Induced Carbonate Precipitation for Strengthening Soft Clay by J. Z. Xiao, Y. Q. Wei, H. Cai, Z. W. Wang, T. Yang, Q. H. Wang, S. F. Wu

“…The water content in MICP-treated specimens was significantly reduced by the MICP reactions and in one case decreased from 40% to 30.73%. (3) The strength enhancement of microbially solidified soft clay is the result of two processes: urea hydration catalyzed by enzymes consumes water in the clay and the bacterially precipitated calcite forms in the sediment’s pores. (4) The micro-organism-produced calcite in the soft clay increases the calcite abundance from 0% to as much as 3.5%. (5) The MICP-treated strength of soft clay varies with the concentration of the nutrients provided. …”
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Effects of Bacillus subtilis-fermented soybean meal replacing fish meal on antioxidant activity, immunity, endoplasmic reticulum stress and hepatopancreas histology in Pacific whit... by Songming Chen, Jieyu Dai, Yan Chen, Qiang Chen, Fen Dong, Congcong Wang, Yulong Sun, Jiteng Wang, Tao Han

“…FSBM substitution did not affect the activities of antioxidant enzymes in the intestine. However, the mRNA expression level of hsp70 in the intestine was significantly reduced by FSBM. …”
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Bibliometric analysis and review of food waste management via sustainable approaches by U. Danya, M. Kamaraj, P. Suresh Babu, J. Aravind

“…Key developments in the field include the optimization of microbial consortia for enhanced degradation and conversion efficiency, as well as the engineering of enzymes to improve specificity and activity. These advancements have led to significant improvements in the efficiency and feasibility of converting food waste into high-value products. …”
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Interactive effects of triploidy induction and culture densities on growth performance and stress, immune, and metabolic responses in juvenile rainbow trout (Oncorhynchus mykiss) by Roghayeh Mahmoudi, Mahdi Naderi, Hakimeh Dopeikar, Seyed Ali Khorasaninasab, Seyed Hadi Seyedalhosseini

“…Chronic high density stress exhibited harmful impacts on liver functions, resulting in elevated activities of serum ALT and AST enzymes (P < 0.05). Also, lipid stores (cholesterol, LDL, HDL, and triglyceride) were depleted due to chronic high density stress. …”
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Systematic review of amyloid-beta clearance proteins from the brain to the periphery: implications for Alzheimer’s disease diagnosis and therapeutic targets by Letian Huang, Mingyue Liu, Ze Li, Bing Li, Jiahe Wang, Ke Zhang

“…The findings revealed significant alterations in the levels of insulin-degrading enzymes, neprilysin, matrix metalloproteinase-9, cathepsin D, receptor for advanced glycation end products, and P-glycoprotein in the brains of patients with Alzheimer’s disease, patients with mild cognitive impairment, and healthy controls. …”
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Visual Analysis of Research Progress on the Impact of Cadmium Stress on Horticultural Plants over 25 Years by Zhouli Liu, Benyang Hu, Yi Zhao, Shuyan Zhang, Xiangbo Duan, Hengyu Liu, Luyang Meng

“…The network of collaborations among authors and institutions in the WOS database seemed denser compared to that in the CNKI database. (3) International research hotspots have focused on accumulation, tolerance and oxidative stress, while domestically, the focus has been on antioxidant enzymes, growth and seed germination. Phytoremediation, subcellular distribution and the transcriptome are the world’s emerging topics, while in China, growth and physiological characteristics are still emerging topics. (4) In comparison, China exhibited a lagging development trend, which is reflected in the fact that it began to focus on gene expression and transcriptome research only after the global frontier shifted towards biochar and cadmium co-stress and yield response. …”
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