Feruloyl-amides as natural antimicrobials for crop and food protection by Denise Dozio, Sharmila Ghosh, Daniele Alessandro Consolini, Josè Luis Ermini Starna, Loris Pinto, Federico Baruzzi, Martina Letizia Contente, Andrea Pinto, Paolo Cortesi, Salvatore Princiotto, Andrea Kunova, Sabrina Dallavalle

“…The main mechanism of defence is based on a rapid transcriptional reprogramming of genes encoding biosynthetic enzymes that synthesize specific secondary metabolites. …”
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Characteristics and bioinformatics of peptides from natural and cultured sandfish (Holothuria scabra) by Pawitporn Daopa, Chakkapat Aenglong, Sittiruk Roytrakul, Teerasak E-kobon, Xue Zhao, Wanwimol Klaypradit

“…LC-MSMS analysis, coupled with bioinformatics database comparisons, indicated that sandfish from natural and cultured sources, as well as different enzymes used in the hydrolysis process, significantly affect protein and peptide pattern. …”
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Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury by Paraschos Archontakis‐Barakakis, Theodoros Mavridis, David‐Dimitris Chlorogiannis, Georgios Barakakis, Eleni Laou, Daniel I. Sessler, George Gkiokas, Athanasios Chalkias

“…Upon reperfusion, intestinal hypoxia may persist because microcirculatory flow remains impaired and/or because available oxygen is consumed by enzymes, intestinal cells and neutrophils.…”
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Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE2-EP2 mediated microglia-neuron signaling by Kunlin Guo, Lei Gao, Ping Li, Shanwu Feng, Liping Zhao, Xian Wang

“…Neurosteroid allopregnanolone is suggested to modulate the expression of various receptors or enzymes that involved in pain perception, presenting an analgesic potential. …”
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Comprehensive identification, characterization and expression analyses of the class III POD gene family in water lily (Nymphaea colorata) by Wasi Ullah Khan, Wasi Ullah Khan, Latif Ullah Khan, Noor Muhammad Khan, Ji Zhang, Wang Wenquan, Wang Wenquan, Fei Chen, Fei Chen

“…Finally, the RT-qPCR based expression and enzymes activity of ten NcPOD genes depicted the dynamically differential response to NaCl, heat, cold, and heavy metals (CuSO4 and CdCl2) stresses. …”
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Direct and Indirect Protein Interactions Link FUS Aggregation to Histone Post-Translational Modification Dysregulation and Growth Suppression in an ALS/FTD Yeast Model by Seth A. Bennett, Samantha N. Cobos, Raven M. A. Fisher, Elizaveta Son, Rania Frederic, Rianna Segal, Huda Yousuf, Kaitlyn Chan, David K. Dansu, Mariana P. Torrente

“…We show that the histone-modifying enzymes Ipl1 and Rtt109—responsible for installing H3S10ph and H3K56ac—are excluded from the nucleus in the context of FUS proteinopathy. …”
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L-Cysteine Treatment Delays Leaf Senescence in Chinese Flowering Cabbage by Regulating ROS Metabolism and Stimulating Endogenous H₂S Production by Linzhi Gan, Zhenliang Mou, Jianye Chen, Wei Shan, Jianfei Kuang, Wangjin Lu, Yating Zhao, Wei Wei

“…Additionally, L-cys treatment maintained high levels of ascorbate and glutathione and activated antioxidant enzymes (superoxide dismutase, peroxidase, and catalase) and the expression of the encoding genes. …”
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Phenolic acids from Anisopus mannii modulates phosphofructokinase 1 to improve glycemic control in patients with type 2 diabetes: A double-blind, randomized, clinical trial by Peter U. Amadi, Justice O. Osuoha, Chidi N. Ekweogu, Suha J. Jarad, Esienanwan E. Efiong, Prince C. Odika, Chioma Ejiofor, Oluchi Aloy-Amadi, Govind S. Gill, Chiamaka W. Adumekwe, Ailun Gaowa, Dawei Zhang, Barbora de Courten, Emmanuel N. Agomuo

“…Among other glycolytic enzymes, in vitro, PhAM counteracted the binding of sodium orthovanadate to phosphofructokinase 1 (PFK-1), improving its activities. …”
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Bionic nanovesicles sequentially treat flaps with different durations of ischemia by thrombolysis and prevention of ischemia-reperfusion injury by Linzhong Yang, Yuanchen Liu, Cheng Tao, Zichen Cao, Shilin Guo, Zheng Wei, Yanyi Wang, Tao Liu, Lin Chen, Ke Xiong, Xingyu Luo, Jianchuan Ran, Wei Han

“…Specifically, we have successfully constructed a clinical-grade bionic vesicle, UK-PBNZ@PM, a system that cleverly incorporates drug components that have been widely used in clinical applications, thereby demonstrating a high degree of clinical translational potential. Prussian blue nano-enzymes (PBNZ) are the core component and demonstrate remarkable efficacy against ischemia-reperfusion injury due to their excellent biocompatibility, robust reactive oxygen species (ROS) scavenging capacity and anti-inflammatory properties. …”
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Carbon Dioxide Micro-Nano Bubbles Aeration Improves Carbon Fixation Efficiency for Succinic Acid Synthesis by <i>Escherichia coli</i> by Ying Chen, Hao Wu, Qianqian Huang, Jingwen Liao, Liuqing Wang, Yue Pan, Anming Xu, Wenming Zhang, Min Jiang

“…The activities of key enzymes within the SA synthesis pathway were also maintained or enhanced in the fermentation process with MNB aeration. …”
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Analysis of the role of acetylation in Giardia lamblia and the giardicidal potential of garcinol by Rocío G. Patolsky, Jerónimo Laiolo, Jerónimo Laiolo, Luciano Díaz-Pérez, Gabriel Luna Pizarro, Gonzalo F. Mayol, María C. Touz, Constanza Feliziani, Andrea S. Rópolo

“…This study investigates the significance of acetylation in this protozoan parasite.MethodsThis study explores the role of acetylation in G. lamblia through a combination of immunofluorescence assays, manipulation of acetyltransferase enzymes, and the use of garcinol, an acetylation inhibitor, during the growth phase.ResultsThe acetylation of histone marks H3K9 and H3K27 occurs during growth and is followed by deacetylation during encystation. …”
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Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice by Yingqun Zhou, Weiqi Dai, Chunlei Lin, Fan Wang, Lei He, Miao Shen, Ping Chen, Chenfen Wang, Jie Lu, Ling Xu, Xuanfu Xu, Chuanyong Guo

“…Levels of serum liver enzymes and histopathology were determined. Levels of inflammatory cytokines with ConA-induced hepatitis were determined with real-time polymerase chain reaction (real-time PCR). …”
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Metagenome-based diversity and functional analysis of culturable microbes in sugarcane by Haidong Lin, Liang Wu, Lijun Zhang, Quang Kiet Ta, Peng Liu, Jinkang Song, Xiping Yang

“…Microbial analysis of carbohydrate-active enzymes (CAZymes) indicated that genes related to sucrose metabolism were mostly present in specific bacterial taxa, including Burkholderia, Pseudomonas, Paraburkholderia, and Chryseobacterium. …”
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Modulation of the endocannabinoid system by (S)-ketamine in an animal model of depression by Nicole R. Silva, Shokouh Arjmand, Luana B. Domingos, Adriano M. Chaves-Filho, Melina Mottin, Caroline C. Real, Anna L. Waszkiewicz, Pedro H. Gobira, Alessio Nicola Ferraro, Anne M. Landau, Carolina H. Andrade, Heidi K. Müller, Gregers Wegener, Sâmia R.L. Joca

“…Changes in eCB receptors and enzymes were assessed at mRNA and protein levels (qPCR and western blot), CB1 binding ([3H]SR141716A autoradiography) and endocannabinoid content (lipidomics). …”
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Genome-Wide Identification of Superoxide Dismutase (<i>SOD</i>) Gene Family in <i>Cymbidium</i> Species and Functional Analysis of <i>CsSOD</i>s Under Salt Stress in <i>Cymbidium s... by Ruyi Li, Songkun Lin, Yin Yan, Yuming Chen, Linying Wang, Yuzhen Zhou, Shuling Tang, Ning Liu

“…Superoxide dismutase (SOD) enzymes are essential for reducing oxidative damage resulting from overabundant reactive oxygen species under abiotic stress. …”
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Investigating the response mechanisms of the intertidal seagrass Zostera japonica to increased UVB radiation through physiological, transcriptomic, and metabolomic analyses by Jiayi Xin, Song Xue, Hongzhen Wang, Xinqi Li, Yu Zang, Lei Liu, Xuexi Tang, Jun Chen

“…To mitigate these adverse effects, the expression levels of genes related to antioxidants and UV-absorbing compounds, including flavonoids (PAL, 4CL, CHS, CHI, F3H) and antioxidant enzymes (DHAR, MDHAR, APX), were upregulated. The increased synthesis of these compounds serves to scavenge accumulated ROS and absorb UV radiation. …”
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Antioxidant, Anti-α-Glucosidase, Anti-Tyrosinase, and Anti-Acetylcholinesterase Components from Stem of <i>Rhamnus formosana</i> with Molecular Docking Study by Chia-Hsuan Tsai, Ya-Lun Liou, Sin-Min Li, Hsiang-Ruei Liao, Jih-Jung Chen

“…Further molecular docking studies revealed that there may be stronger binding mechanisms between bioactive components and target enzymes (including α-glucosidase, acetylcholinesterase, and tyrosinase) than the positive control. …”
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Lactiplantibacillus plantarum AR113 alleviates microbiota dysbiosis of tongue coating and cerebral ischemia/reperfusion injury in rat by Zhiqiang Xiong, Gang Liu, Ling Fang, Xiuming Li, Yongjun Xia, Guangqiang Wang, Xin Song, Lianzhong Ai

“…AR113 partly restored I/R induced change of TCM and gut microbiota with significantly improved neurological deficit, relieved histopathologic change, increased activities of antioxidant enzymes, and decreased contents of oxidative stress biomarkers. …”
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Proximity‐dependent biotinylation reveals an interaction between ubiquitin‐specific peptidase 46 and centrosome‐related proteins by Kazuma Yoshioka, Reiko Nakagawa, Chi Lieu Kim Nguyen, Hayate Suzuki, Kiyohiro Ishigaki, Seiya Mizuno, Tsukasa Okiyoneda, Shizufumi Ebihara, Kazuya Murata

“…Ubiquitination is a reversible post‐translational modification, and deubiquitinating enzymes cleave ubiquitin from proteins. Ubiquitin‐specific peptidase 46 (USP46), a deubiquitinase, is highly expressed in the brain and regulates neural functions. …”
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The proposed protein and carbohydrate ingredients and the acceptance of moist feed by newly hatched Bigfin reef squid (Sepioteuthis lessoniana) by Natthawut Chanlek, Jirapan Satjarak, Yuzuru Ikeda, Nutt Nuntapong, Karun Thongprajukaew

“…Here, thirty sources of protein and seven of carbohydrate were tested for in vitro digestibility using digestive enzymes from viscera of Bigfin reef squid. Suitable protein ingredients included the meat of blue swimming crab, catfish, emperor fish, Indian anchovy, Indian mackerel, Nile tilapia, Pacific white shrimp, striped catfish, trash fish and yellow-stripe scad. …”
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