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  1. 4501

    Gestational Age at Delivery Is an Independent Predictor of Neonatal Outcome for Maternal HELLP Syndrome by Yan Shi, Xiaoli Yang, Chengqin Wang, Luosong Zhuoga, Dongmei Xu

    Published 2025-01-01
    “…Abstract Hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome is a severe complication of preeclampsia (PE), with a higher incidence rate in people living at high altitudes, such as Tibet area. …”
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  2. 4502

    Effect and Safety of Mycophenolate Mofetil in Idiopathic Pulmonary Fibrosis by Argyris Tzouvelekis, Evangelos Bouros, Anastasia Oikonomou, Paschalis Ntolios, George Zacharis, George Kolios, Demosthenes Bouros

    Published 2011-01-01
    “…No cases of clinically significant infection, leucopenia, or elevated liver enzymes were recorded. Conclusions. MMF is a safe therapeutic modality which failed to show a beneficial effect both in functional and radiological parameters in a small cohort of IPF patients.…”
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  3. 4503

    Encapsulation and Melanization Are Not Correlated to Successful Immune Defense Against Parasitoid Wasps in <i>Drosophila melanogaster</i> by Lilla B. Magyar, István Andó, Gyöngyi Cinege

    Published 2025-01-01
    “…Expression profiles of the <i>PPO2</i> and <i>PPO3</i> prophenoloxidase genes, which encode key enzymes in the melanization reaction, were detected by qRT-PCR. …”
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  4. 4504
  5. 4505

    Enhanced Hydrothermal Depolymerization with Fe/Ni Loaded C Catalysts for Improving Anaerobic Digestion Performance of Corn Stover by Xitong Wang, Chenyang Zhu, Hairong Yuan, Xiujin Li

    Published 2025-01-01
    “…The crystallinity index (CrI) of depolymerized CS was significantly reduced from 32.5% to 23.5%, allowing for a more easily biodegradable non-crystalline area to be available for enzymes. Meanwhile, the DC group produced 4.7 times more reducing sugar (RS), and a 3.4 times increase in total volatile fatty acids (VFAs) as compared to the control. …”
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  6. 4506

    Effect of Adalimumab on Refractory Arthritis in Juvenile Idiopathic Inflammatory Myopathy with Anti-MDA5 Autoantibody by Takako Miyamae, Takuma Hara, Aki Hanaya, Yumi Tani, Takayuki Kishi, Hisashi Yamanaka

    Published 2018-01-01
    “…Based on muscle weakness, elevated muscle-derived enzymes, magnetic resonance imaging, and skin biopsy results, the diagnosis was juvenile idiopathic inflammatory myopathies (JIIM). …”
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    Article
  7. 4507

    From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges by Wei Du, Xinyue Wang, Yuyan Zhou, Wencheng Wu, Haojie Huang, Zhendong Jin

    Published 2025-01-01
    “…This is caused by the abnormal activation of pancreatic enzymes by a variety of etiologic factors, which results in a localized inflammatory response. …”
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  8. 4508

    Unveiling early-life microbial colonization profile through characterizing low-biomass maternal-infant microbiomes by 2bRAD-M by Shuwen Hou, Yuesong Jiang, Feng Zhang, Tianfan Cheng, Dan Zhao, Jilong Yao, Ping Wen, Ping Wen, Lijian Jin, Shi Huang

    Published 2025-01-01
    “…However, analyzing these samples often faces technical challenges and limitations of low-resolution using conventional approaches due to their low microbial biomass.MethodsHere, we employed the type IIB restriction enzymes site-associated DNA sequencing for microbiome (2bRAD-M) as a reduced metagenomics method to address these issues and profile species-level microbial composition. …”
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  9. 4509

    Phytochemical Analysis and Cholinesterase Inhibitory and Antioxidant Activities of Enhydra fluctuans Relevant in the Management of Alzheimer’s Disease by Simin Shabnam Lopa, Md. Yusuf Al-Amin, Md. Kamrul Hasan, Md. Salim Ahammed, KM Monirul Islam, A. H. M. Khurshid Alam, Toshihisa Tanaka, Md. Golam Sadik

    Published 2021-01-01
    “…Among the four tested extracts, the chloroform extract was found to exert the highest inhibition against both the acetylcholinesterase and butyrylcholinesterase enzymes with the IC50 (concentration required for 50% inhibition) values of 83.90 μg/mL and 48.14 μg/mL, respectively. …”
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  10. 4510

    L-selenomethionine inhibits small intestinal ferroptosis caused by ammonia exposure through regulating ROS-mediated iron metabolism by Xinxin Zhang, Lepeng Gu, Ying Chen, Tianqi Wang, Houjuan Xing

    Published 2025-01-01
    “…The results showed that ammonia exposure up-regulated the levels of iron, ROS, MDA, and LPO in the small intestinal tissue and the IPEC-J2 cell, down-regulated the activities of antioxidant enzymes and the content of GSH, inhibited the Nrf2 pathway, significantly altered the expression of ferroptosis (TFR-1, FPN-1, FTH1, SLC7A11, GPX4, ACSL4) and intestine tight junctions (Claudin-1, Occludin, ZO-1) genes. …”
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  11. 4511
  12. 4512

    Liraglutide Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism via SHP1/AMPK Signaling Pathway by Peng Yu, Xi Xu, Jing Zhang, Xuan Xia, Fen Xu, Jianping Weng, Xiaoyang Lai, Yunfeng Shen

    Published 2019-01-01
    “…LR administration significantly lowered the serum lipid profile and lipid disposition in vitro and in vivo because of the altered expression of enzymes on hepatic gluconeogenesis and lipid metabolism. …”
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  13. 4513

    Immunization of cattle with a Rhipicephalus microplus chitinase peptide containing predicted B-cell epitopes reduces tick biological fitness by María Martina Esperanza Perez-Soria, Daniel Gustavo López-Díaz, Rafael Jiménez-Ocampo, Gabriela Aguilar-Tipacamú, Massaro W. Ueti, Juan Mosqueda, Ala Tabor

    Published 2024-08-01
    “…To develop novel tick vaccines, it is crucial to identify and evaluate antigens capable of generating protection in cattle. Chitinases are enzymes that degrade older chitin at the time of moulting, therefore allowing interstadial metamorphosis. …”
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  14. 4514

    Selenium’s Role in Plant Secondary Metabolism: Regulation and Mechanistic Insights by Yan Zhou, Kaiqin Nie, Lulu Geng, Yixin Wang, Linling Li, Hua Cheng

    Published 2024-12-01
    “…Although it has been shown that selenium can affect the antioxidant system and defense mechanisms in plants, detailed mechanisms of selenium’s action on plant secondary metabolic pathways, including its effects on specific metabolic enzymes and regulatory genes, still need to be revealed by further in-depth studies. …”
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  15. 4515

    Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion by Katsuya Sakimura, Tatsuya Maekawa, Shin-ichi Kume, Takeshi Ohta

    Published 2018-01-01
    “…To get an insight into the mechanism underlying the impaired melatonin secretion in SDT fatty rats, the expression of arylalkylamine N-acetyltransferase (Aanat) and acetylserotonin O-methyltransferase (Asmt) mRNA, which encode the rate-limiting enzymes for melatonin synthesis, was investigated in the pineal gland. …”
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  16. 4516

    Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats by Igor Y. Iskusnykh, Tatyana N. Popova, Aleksander A. Agarkov, Miguel Â. A. Pinheiro de Carvalho, Stanislav G. Rjevskiy

    Published 2013-01-01
    “…It can be proposed that the overexpression of these enzymes could be a mechanism of enhancement of hepatocytes tolerance to oxidative stress.…”
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  17. 4517

    Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines by Edismauro Garcia Freitas Filho, Elaine Zayas Marcelino da Silva, Camila Ziliotto Zanotto, Constance Oliver, Maria Célia Jamur

    Published 2016-01-01
    “…The effect of cross-linking these gangliosides on the activation of enzymes in the arachidonate cascade was then investigated. …”
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  18. 4518

    The adaptation of rainbow trout to warmer water: Oxidative damage in the germinal line by Vianel Sevastei, Sonia A. Crichigno, M. Victoria Santos, Andrea Trochine, Julio C. Painefilú, Noemí Zaritzky, Víctor E. Cussac

    Published 2025-01-01
    “…We examined: Oxidative damage (lipid peroxidation) and activities of antioxidant enzymes; Catalase (CAT), Glutathione S-Transferases (GST), and Superoxide Dismutase (SOD), in liver, testicle, and spermatozoa. …”
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  19. 4519

    Effects of aluminum on metabolism of reactive oxygen species and reactive nitrogen species in root tips of different Eucalyptus species by Zilong Ouyang, Bing Liu, Tangkan Li, Tiandao Bai, Weichao Teng

    Published 2025-01-01
    “…By observing the occurrence and distribution of the main reactive oxygen species (ROS) and reactive nitrogen species (RNS) in root tips of Eucalyptus seedlings under Al stress, this study analyzed change in the growth and physiological indexes of Eucalyptus seedlings under Al stress. The antioxidant enzymes activities of the root tips of different Eucalyptus species induced by Al stress resulted in different ROS and RNS contents, ultimately resulting in differing degrees of membrane lipid peroxidation. …”
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  20. 4520

    Colada morada, a traditional Ecuadorian Day of the dead beverage: Bibliometric analysis and review of the biological activity of native Ecuadorian ingredients by Juan Carlos Romero-Benavides, Rodrigo Duarte-Casar, Marlene Rojas-Le-Fort, Natalia Bailon-Moscoso

    Published 2025-03-01
    “…Using bibliometric analysis and document reviews, we identified major bioactive compounds such as phenolic acids, anthocyanins, flavonoids, terpenoids, and proteolytic enzymes, which exhibit antioxidant, antimicrobial, anti-inflammatory, and chemopreventive properties. …”
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