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4421
Black mulberry (Morus nigra L.) prevents deleterious effects of excess glucose in obese C. elegans decreasing lipofuscin accumulation and ROS production
Published 2025-01-01“…Morus nigra was also able to inhibit the pancreatic enzymes α-amylase and lipase and could be considered an interesting traditional food ingredient in the prevention of certain metabolic diseases.…”
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4422
In vitro assessment of the nematicidal potential of Streptomyces violascens strain AS2 against root-knot nematodes (Meloidogyne sp.)
Published 2024-01-01“…Enzymatic profiles supported these results, with the selected isolate producing chitinase and protease enzymes capable of degrading nematode eggshells. Our results show that the S. violascens strain can be integrated into a sustainable nematode management practice as an important agent of RKN biocontrol.…”
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4423
In-depth proteomic profiling identifies potentiation of the LPS response by 7-ketocholesterol
Published 2025-03-01“…Rather, they prime the macrophage, potentiating LPS-stimulated TNF alpha secretion and key pro-inflammatory enzymes. Our results indicate that 7-KC has independent metabolic effects on the macrophage; however, effects on the immune system are primarily due to the changes in metabolism priming the response to an inflammatory stimulus. …”
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4424
Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation
Published 2013-01-01“…The expression profiles of adiponectin, resistin, 5′-AMP-activated protein kinase α (AMPKα), hypoxia-inducible factor-1α (HIF-1α), and key enzymes of glucose and fatty acid metabolism and oxidative phosphorylation in rat retroperitoneal white adipose tissue (RpWAT) during 45-day cold acclimation were examined. …”
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4425
Plant Growth-Promoting and Herbicidal Bacteria as Potential Bio-Based Solutions for Agriculture in Desertic Regions
Published 2024-12-01“…These bacteria possess in vitro plant growth-promoting traits, the ability to produce hydrolytic enzymes, and the capacity to inhibit phytopathogenic fungi. …”
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4426
Microalga <i>Nannochloropsis gaditana</i> as a Sustainable Source of Bioactive Peptides: A Proteomic and In Silico Approach
Published 2025-01-01“…Molecular docking demonstrated strong affinities with key enzymes such as MPO, ACE, and DPPIV. Resistance to the digestion, capacity to be absorbed, and multifunctionality were demonstrated for peptide FIPGL. …”
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4427
The protective effect of dietary flavonoid fraction from Acanthophora spicifera on streptozotocin induced oxidative stress in diabetic rats
Published 2016-06-01“…The antioxidant consequences of FRF on STZ-induced diabetic rats were determined by the estimations of the oxidative stress marker like malonyldialdehyde and antioxidant enzymes such as superoxide dismutase, catalase and glutathione in tissue homogenates of heart, liver and kidney. …”
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4428
Sophocarpine Attenuates LPS-Induced Liver Injury and Improves Survival of Mice through Suppressing Oxidative Stress, Inflammation, and Apoptosis
Published 2018-01-01“…We found that sophocarpine increases the survival rate of mice and attenuates the LPS-induced liver injury, which is indicated by pathology and serum liver enzymes. Further research found that sophocarpine ameliorated hepatic oxidative stress indicators (H2O2, O2∙−, and NO) and enhanced the expression of antioxidant molecules such as superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). …”
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4429
Fever, Myositis, and Paralysis: Is This Inflammatory Myopathy or Neuroinvasive Disease?
Published 2016-01-01“…At 12-month follow-up his muscle enzymes had normalized and his weakness had improved to 5/5 strength in bilateral legs and 3/5 strength in the right arm.…”
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4430
Structural basis of SIRT7 nucleosome engagement and substrate specificity
Published 2025-02-01“…Abstract Chromatin-modifying enzymes target distinct residues within histones to finetune gene expression profiles. …”
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4431
Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects
Published 2021-01-01“…Previous studies suggested that the coculture of human MSCs with AD in an in vitro model reduced the expression of amyloid-beta 42 (Aβ42) in the medium as well as the overexpression of amyloid-beta- (Aβ-) degrading enzymes such as neprilysin (NEP). We focused on the role of primed MSCs (human Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) exposed to an AD cell line via a coculture system) in reducing the levels of Aβ and inhibiting cell death. …”
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4432
α-Amylase and α-Glucosidase Inhibitory Activities of Chemical Constituents from Wedelia chinensis (Osbeck.) Merr. Leaves
Published 2018-01-01“…Other compounds showed weak or did not show any effect on both enzymes. The results suggested that the antidiabetic properties from the leaves of W. chinensis are not simply a result of each isolated compound but are due to other components such as the accessibility of polyphenolic groups to α-amylase and α-glucosidase activities.…”
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4433
Nitric oxide in exercise physiology: past and present perspectives
Published 2025-01-01“…NO also plays a role in the redox state within the skeletal muscle, partially through its interaction with respiratory chain enzymes and transcriptional regulators of antioxidant production. …”
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4434
In vitro characterization of lactic acid bacteria and bifidobacteria from wild and domestic pigs: probiotic potential for post-weaning piglets
Published 2025-01-01“…Moreover, more CDS encoding carbohydrateactive enzymes (CAZymes) were carried in the genomes of strains obtained from wild boars. …”
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4435
Applying Machine Learning Techniques to Identify Undiagnosed Patients with Exocrine Pancreatic Insufficiency
Published 2019-02-01“…**Background:** Exocrine pancreatic insufficiency (EPI) is a serious condition characterized by a lack of functional exocrine pancreatic enzymes and the resultant inability to properly digest nutrients. …”
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4436
Resin-Dentin Bonding Interface: Mechanisms of Degradation and Strategies for Stabilization of the Hybrid Layer
Published 2019-01-01“…The aqueous inclusions within the hybrid layer serve as a functional medium for the hydrolysis of the resin matrix, giving rise to the activity of esterases and collagenolytic enzymes, such as matrix metalloproteinases, which play a fundamental role in the degradation process of the hybrid layer. …”
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4437
Effects of Sildenafil and Vitamin E on Paraquat-Induced Pulmonary Fibrosis in Rats
Published 2024-12-01“…Drugs like sildenafil, which inhibits phosphodiesterase enzymes, are used to treat pulmonary arterial hypertension. …”
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4438
Modulatory effects of cinnamomi cortex and its components epicatechin and linalool on skin circadian rhythms
Published 2025-02-01“…Furthermore, EC and LO demonstrated significant antioxidant activities, as evidenced by reduced reactive oxygen species levels and increased expression of antioxidant enzymes. EC and LO also upregulated skin barrier-related and ceramide synthesis genes and modulated the expression of cellular longevity-promoting genes. …”
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4439
Antihyperlipidemic Effects of Sesamum indicum L. in Rabbits Fed a High-Fat Diet
Published 2013-01-01“…Supplementation with sesame oil, but not sesame seed, can ameliorate serum levels of lipids and hepatic enzymes in rabbits under a high-fat diet.…”
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4440
Effectiveness of Antioxidants and Resistance to Diamondback Moth Infestation in Green Mustard Plants Using Ethanol Extracts from Millettia pachyloba Drake Leaves: An In Vitro and I...
Published 2025-01-01“…Moreover, MPDE exhibited significant antioxidant activity and reversed DBM-induced inhibition of antioxidant enzymes, reducing oxidative stress. These findings suggest that MPDE is a promising, eco-friendly alternative to chemical pesticides, enhancing pest resistance and oxidative stress tolerance in plants.…”
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