Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV by Anna K. Coussens, Adrian R. Martineau, Robert J. Wilkinson

“…Conversely, vitamin D can act to inhibit expression and secretion of a broad range of inflammatory mediators and matrix degrading enzymes driving immunopathology during active TB and antiretroviral- (ARV-) mediated immune reconstitution inflammatory syndrome (IRIS). …”
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BACE1 Is Necessary for Experience-Dependent Homeostatic Synaptic Plasticity in Visual Cortex by Emily Petrus, Hey-Kyoung Lee

“…Similarly, physiological functions for β- and γ-secretases, the two key enzymes that produce Aβ by sequentially processing the amyloid precursor protein (APP), have been discovered over recent years. …”
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Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion. by Francois Dao, Amadou Niangaly, Fanta Sogore, Mamadou Wague, Djeneba Dabitao, Siaka Goita, Aboubacrin S Hadara, Ousmaila Diakite, Mohamed Maiga, Fatoumata O Maiga, Chantal Cazevieille, Cecile Cassan, Arthur M Talman, Abdoulaye A Djimde, Alejandro Marin-Menendez, Laurent Dembélé

“…However, when RBCs were pre-treated with various enzymes (neuraminidase, trypsin, and chymotrypsin), we observed a significant reduction in P. malariae invasion, albeit not a complete blockade. …”
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Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress by Md. Yusuf Al-Amin, Amitav Lahiry, Rafia Ferdous, Md. Kamrul Hasan, Md. Abdul Kader, AHM Khurshid Alam, Zahangir Alam Saud, Md. Golam Sadik

“…Among the crude extract and its fractions, chloroform fraction exerted strong inhibition of acetylcholinesterase and butyrylcholinesterase enzymes with IC50 values of 40.06 and 18.78 µg/mL, respectively. …”
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Monosodium glutamate (MSG) exposure induced oxidative stress and disrupted testicular hormonal regulation, exacerbating reproductive dysfunction in male WISTAR rats by Adesua Emmanuel Ogunmokunwa, Babatunde Oluwaseun Ibitoye

“…Conversely, the activities of antioxidant enzymes (SOD, CAT, GSH, GPx) were significantly diminished, reflecting impaired antioxidant defences. …”
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Liver Injury Secondary to Anti-TNF-Alpha Therapy in Inflammatory Bowel Disease: A Case Series and Review of the Literature by Ravish Parekh, Nirmal Kaur

“…Liver biopsy was performed in all 3 patients, and evidence of portal inflammation was seen. Liver enzymes normalized after discontinuation of therapy in all patients, and no long term effects have been observed. …”
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FACS‐Sortable Triple Emulsion Picoreactors for Screening Reactions in Biphasic Environments by Samuel Thompson, Yanrong Zhang, Zijian Yang, Lisa Nichols, Polly M. Fordyce

“…These triple emulsion picoreactors have the potential for future screening bead‐encoded catalyst libraries, including enzymes such as lipases for biofuel production.…”
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N-Oxalylglycine-Conjugated Hyaluronic Acid as a Macromolecular Prodrug for Therapeutic Angiogenesis by Andrew H. DeMaria, Jeoung Soo Lee, Ken Webb

“…NOG was conjugated to HA by esterification, and release was significantly increased in the presence of degradative enzymes, esterase and hyaluronidase, compared to physiological buffer, confirming that the release of NOG is primarily enzymatically driven. …”
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Characterization of Enterobacter phage vB_EcRAM-01, a new Pseudotevenvirus against Enterobacter cloacae, isolated in an urban river in Panama. by Ednner E Victoria-Blanco, Jean Pierre González-Gómez, Juan Raúl Medina-Sánchez, Alexander A Martínez, Nohelia Castro Del Campo, Cristóbal Chaidez-Quiroz, Jordi Querol-Audi, Alex Omar Martínez-Torres

“…Among them, protein-encoding genes involved in morphology, inactivation, adsorption to cells, DNA injection and lytic enzymes were identified. Additionally, the genome contained two tRNA sequences. …”
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GENES DETERMINING THE SYNTHESIS OF LAVONOID AND MELANIN PIGMENTS IN BARLEY by O. Yu. Shoeva, K. V. Strygina, E. K. Khlestkina

“…Since the 1970s, structural genes that encode the enzymes of lavonoid metabolism, as well as regulatory genes that determine the tissue-speciic accumulation of these pigments in grain tissues, as well as in vegetative organs have been identiied and localized in the barley genome. …”
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Effect of Cannabis seeds on Some biomedical parameters in male rats by Karwan Anwar Hassan

“…Alkaline Phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT), creatinine and uric acid was done for estimating the effect of cannabis seeds on renal and liver function. Enzymes Alkaline phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT) as well as creatinine, uric acid and very low-density lipoprotein (VLDL) were not significantly (p<0.05) different in both groups. …”
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Comprehensive analysis of adverse events associated with onasemnogene abeparvovec (Zolgensma) in spinal muscular atrophy patients: insights from FAERS database by Wenwen Zhang, Yizhen Yin, Dan Yang, Mengyuan Liu, Caixia Ye, Ruiling Yan, Ruiman Li

“…This study identified 281 onasemnogene abeparvovec-related adverse events (AEs), including some significant adverse events not mentioned in the product labelling. Elevated liver enzymes, fever, vomiting, and thrombocytopenia were the most common adverse reactions. …”
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Study of platelet activation, hypercoagulable state, and pulmonary hypertension in patients with transfusion-dependent beta-thalassemia by Lanja Othman Haji, Ranan Kardagh Polus, Nawsherwan Sadiq Mohammed

“…RESULTS: Thalassemia patients revealed severe anemia, leukocytosis, thrombocytosis, significantly elevated serum ferritin (1957.50 ± 2455.05 g/L), elevated liver enzymes serum glutamic oxaloacetic transaminase (22.01 ± 9.89 U/L), serum glutamic pyruvic transaminase (22.70 ± 9.78 U/L) in comparison to controls, and mean serum P-selectin was significantly higher in thalassemic patients (100.48 ± 53.29 ng/mL). …”
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Boosting curcumin bioavailability with egg white protein aerogels: A sustainable supercritical CO₂-based approach for enhanced bioaccessibility, antioxidant activity, and anti-infl... by Farhad Alavi, Ozan N. Ciftci

“…Digestibility analysis confirmed the efficient breakdown of EWP aerogels by digestive enzymes, emphasizing their potential as food-grade, nutritious carriers for controlled release and nutraceutical delivery. …”
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Protein Ubiquitylation in Pancreatic Cancer by Thomas Bonacci, Julie Roignot, Philippe Soubeyran

“…Indeed, despite its role in promoting protein degradation through the proteasome, ubiquitylation is now known to regulate diverse cellular processes, such as membrane protein endocytosis and intracellular trafficking, assembly of protein complexes, gene transcription, and activation or inactivation of enzymes. Taking into account that ubiquitylation machinery is a three-step process involving hundreds of proteins, which is countered by numerous ubiquitin hydrolases, and that the function of ubiquitylation relies on the recognition of the ubiquitin signals by hundreds of proteins containing a ubiquitin binding domain (including the proteasome), the number of possible therapeutic targets is exceptionally vast and will need to be explored carefully for each disease. …”
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Effect of Cannabis seeds on Some biomedical parameters in male rats by Karwan Anwar Hassan

“…Alkaline Phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT), creatinine and uric acid was done for estimating the effect of cannabis seeds on renal and liver function. Enzymes Alkaline phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT) as well as creatinine, uric acid and very low-density lipoprotein (VLDL) were not significantly (p<0.05) different in both groups. …”
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Effect of Cannabis seeds on Some biomedical parameters in male rats by Karwan Anwar Hassan

“…Alkaline Phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT), creatinine and uric acid was done for estimating the effect of cannabis seeds on renal and liver function. Enzymes Alkaline phosphatase, glutamic oxaloacetic transaminase and glutamic pyruvic transaminase (ALP, GPT, and GOT) as well as creatinine, uric acid and very low-density lipoprotein (VLDL) were not significantly (p<0.05) different in both groups. …”
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Non-coding parts of genomes as the basis of epigenetic heredity by R. N. Mustafin, E. K. Khusnutdinova

“…The evolutionary conservation of a complex enzymes Drosha, Dicer, Argonaut, RdRP and their homologues in all multicellular eukaryotes, and their absence in unicellular organisms supports this assumption. …”
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Aquaporin 12 Is Expressed in the Stomach and Liver of the Spiny Dogfish (<i>Squalus acanthias</i>) by Christopher P. Cutler, Jade Bender, Sarah Conner, Esosa Omoregie

“…This localization is reminiscent of the AQP12 localization in pancreatic acinar cells, where it is found in the membrane of zymogen granules containing digestive enzymes.…”
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The Stability of a Model Substrate for Topoisomerase 1-Mediated DNA Religation Depends on the Presence of Mismatched Base Pairs by William H. Gmeiner, Freddie Salsbury, Chris M. Olsen, Luis A. Marky

“…Topoisomerase 1 (Top1) enzymes regulate DNA superhelicity by forming covalent cleavage complexes that undergo controlled rotation. …”
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