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4221
Multiple action sites of ultrasound on Escherichia coli and Staphylococcus aureus
Published 2018-03-01“…The result in this study also showed that a proportion of bacteria subpopulation suffered from serious damage of intracellular components (e.g. DNA and enzymes) but with intact cell envelopes. We speculated that the inactivated effects of ultrasound on microbes might more than simply completed disruption of cell exteriors. …”
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4222
Proteolytic Processing of CD44 and Its Implications in Cancer
Published 2021-01-01“…One modification that has provoked interest is the consecutive cleavage of the CD44 extracellular ectodomain by enzymes that belong mainly to the family of metalloproteases. …”
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4223
Hypoglycemic polysaccharides from Auricularia auricula and Auricularia polytricha inhibit oxidative stress, NF-κB signaling and proinflammatory cytokine production in streptozotoci...
Published 2021-01-01“…This is the first report to compare the effectiveness of AAP and APP in combating streptozotocin-induced oxidative stress and diabetes-related changes in mice (body weight, fasting blood glucose, serum insulin, proinflammatory mediator and cytokines, oxidative stress-related products, antioxidant enzymes). APP and AAP with different molecular weights and monosaccharide molar ratios could be therapeutic options for diabetes with a low dose (100 mg/kg/day) likely working better. …”
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4224
Design, Synthesis, Molecular Docking, and Antibacterial Evaluation of Some Novel Flouroquinolone Derivatives as Potent Antibacterial Agent
Published 2014-01-01“…To understand the interaction of binding sites with bacterial protein receptor, the docking study was performed using topoisomerase II DNA gyrase enzymes (PDB ID: 2XCT) by Schrodinger’s Maestro program. …”
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4225
The effects ofesterified glucomannan on some biochemical parameters during experimental aflatoxicosis in japanese quails
“…In the blood samples taken on the 21st and 42nd day. it was determined decrease in total protein (TP), albumin, tryglyseride, cholesterole, glucose, calcium (Ca). inorganic phosphorus (IP), and blood urea nitrogen (BUN) levels and increase in alanineaminotransferase (ALT) and aspartatearninotransferase enzymes activities in the AF ve AF+GM1 groups (P<0.05). …”
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4226
Functional Development of the Human Gastrointestinal Tract: Hormone- and Growth Factor-Mediated Regulatory Mechanisms
Published 2004-01-01“…In the third section, emphasis is placed on the functional development of human fetal stomach and its various epithelial cell types; in particular, the glandular chief cells responsible for the synthesis and secretion of gastric enzymes such as pepsinogen-5 and gastric lipase. Bearing in mind that limitations of available cell models have, until now, greatly impeded the comprehension of molecular mechanisms regulating human gastric epithelial cell functions, the last section focuses on new human gastric epithelial cell models recently developed in the author's laboratory. …”
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4227
Pyogenic Liver Abscess Caused by Methicillin-Susceptible Staphylococcus aureus in a 21-Year-Old Male
Published 2018-01-01“…Labs were significant for leukocytosis with predominant neutrophilia and elevated liver enzymes. CT abdomen with contrast revealed an 8.4 cm multiloculated right hepatic mass extending to the kidney. …”
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4228
Case Report: Necrotizing pneumonia in pediatric patients: a rare case of unilateral necrosis in two entire lobe tissues
Published 2025-01-01“…Laboratory investigations revealed elevated white blood cell count, increased inflammatory markers, elevated liver enzymes, coagulation dysfunction, and hypoalbuminemia. …”
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4229
Recapitulation of previously reported associations for type 2 diabetes and metabolic traits in the 126K East Asians
Published 2019-12-01“…In this study, we validated 422 variants independently associated with glycemic indexes, liver enzymes, and type 2 diabetes in 125,872 samples from a Korean population, and further validated the results by assessing publicly available summary statistics from European GWAS (n = 898,130). …”
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4230
Unraveling cerebroprotective potential of fenchone: A combined in vivo and in silico exploration of nitric oxide synthase modulation
Published 2025-01-01“…Additionally, FEN restored the activity of antioxidant enzymes (catalase and superoxide dismutase) and decreased malondialdehyde (MDA) and nitric oxide (NO) levels and infarct size compared to those in untreated ischemic rats. …”
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4231
DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting Alone
Published 2017-01-01“…However, when acting alone, MTDs or HMGB1 did not upregulate cartilage degrading enzymes or iNOS. Conclusion. MTDs or HMGB1 could only stimulate inflammatory response in chondrocytes with the presence of cytokines or Fn-f.…”
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4232
Histopathological, Immunohistochemical and Biochemical Studies of Murine Hepatosplenic Tissues Affected by Chronic Toxoplasmosis
Published 2022-01-01“…The biochemical profile of the liver has been changed in the form of increased liver enzymes, and oxidative stress has been evidenced by elevated nitric oxide (NO) concentration in liver homogenate. …”
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4233
Effects of Fungi-Mediated Solid-State Fermentation on Phenolic Contents and Antioxidant Activity of Brown and White Teff (Eragrostis tef (Zucc.) Trotter) Grains
Published 2020-01-01“…Such changes are suggested to be attributed to activities of fungal enzymes such as amylases, xylanases, and proteases that induce structural breakdown of grain components including cell walls leading to the liberation or synthesis of a variety of phenolic compounds. …”
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4234
Microwave-Assisted Synthesis of Cross-Linked Co-poly(itaconic anhydride-methyl methacrylate): The Effects of the Molar Ratio and Cross-Linking Agent on the Thermal Stability
Published 2020-01-01“…The copolymers containing itaconic anhydride (ITA) and methyl methacrylate (MMA) were chosen due to the formation of long-term stable anhydride moieties, which might be useful to attach enzymes covalently with numerous applications in water treatment. …”
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4235
Warfarin Dosing in a Patient with CYP2C9*3*3 and VKORC1-1639 AA Genotypes
Published 2014-01-01“…Genetic factors most correlated with warfarin dose requirements are variations in the genes encoding the enzymes cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKOR). …”
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4236
Sulbactam–Durlobactam: A Novel Antibiotic Combination for the Treatment of Acinetobacter baumannii–Calcoaceticus Complex (ABC) Hospital-Acquired Bacterial Pneumonia and Ventilator-...
Published 2025-01-01“…Reported adverse events include anemia, elevated liver enzymes, hyperkalemia, headache, diarrhea, nausea, urticaria, and vascular pain. …”
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4237
In Vivo and Ex Vivo Evaluation of 1,3-Thiazolidine-2,4-Dione Derivatives as Euglycemic Agents
Published 2021-01-01“…At the end of the experiment, tissue samples were collected to quantify the level of glucose, insulin, triglycerides, total cholesterol, and liver enzymes, as well as enzymatic and nonenzymatic antioxidant activity. …”
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4238
Alcohol and cancer: the role of cytochrome P-4502E1
Published 2024-05-01“…CYP2E1 is one of 57 cytochrome P450 enzymes that are responsible for over 90% of the redox reactions of chemicals, including drugs, vitamins, steroids, chemical carcinogens, and industrial compounds. …”
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4239
Duodenal Obstruction during Pregnancy
Published 2022-01-01“…Intractable vomiting and elevated liver enzymes during pregnancy seem to be associated to the obstetric etiologies; however, other causes such as acute surgical emergencies should be considered. …”
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4240
Comparative Neuroprotective Effects of Dexamethasone and Minocycline during Hepatic Encephalopathy
Published 2014-01-01“…Methods. 48 male albino rats were divided into 4 groups: control group, acute liver injury (ALI) group, minocycline pretreated ALI group, and dexamethasone pretreated ALI group. 24 hours after acute liver injury serum ammonia, liver enzymes, brain levels of heme oxygenase-1 gene, iNOS gene expression, nitrite/nitrate, and cytokines were measured. …”
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