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4141
Comprehensive Analysis of β-1,3-Glucanase Genes in Wolfberry and Their Implications in Pollen Development
Published 2024-12-01“…β-1,3-Glucanases (Glu) are key enzymes involved in plant defense and physiological processes through the hydrolysis of β-1,3-glucans. …”
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4142
Role of Lactate in Inflammatory Processes: Friend or Foe
Published 2022-01-01“…Additionally, various targets, including post-translational modifications, G-protein coupled receptor and transcription factor activation such as NF-κB and HIF-1, allow lactate to modulate signaling pathways that control the expression of cytokines, chemokines, adhesion molecules, and several enzymes associated with immune response and metabolism. …”
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4143
Unexpectedly life-threatening meal: Contamination by Bongkrekic acid in Taiwan
Published 2025-01-01“…On examination, refractory hypotension, jaundice, diffuse abdominal pain, high levels of liver enzymes, metabolic acidosis, coagulopathy, and acute hepatic failure were present. …”
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4144
Atom-Driven and Knowledge-Based Hydrolysis Metabolite Assessment for Environmental Organic Chemicals
Published 2025-01-01“…The metabolism of environmental organic chemicals often relies on the catalytic action of specific enzymes at the nanoscale, which is critical for assessing their environmental impact, safety, and efficacy. …”
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4145
Skeletal Muscle Mitochondria and Aging: A Review
Published 2012-01-01“…Animal and human studies typically show that skeletal muscle mitochondria are altered with aging, including increased mutations in mitochondrial DNA, decreased activity of some mitochondrial enzymes, altered respiration with reduced maximal capacity at least in sedentary individuals, and reduced total mitochondrial content with increased morphological changes. …”
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4146
Exploration of the Role of Cyclophilins in Established Hepatitis B and C Infections
Published 2024-12-01“…Cyclophilin (Cyp) inhibitors are of clinical interest in respect to their antiviral activities in the context of many viral infections including chronic hepatitis B and C. Cyps are a group of enzymes with peptidyl-prolyl isomerase activity (PPIase), known to be required for replication of diverse viruses including hepatitis B and C viruses (HBV and HCV). …”
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4147
Animal-based evidence supports protective activity of bioengineered silver and gold nanomaterials on hepatic and renal function profile parameters
Published 2025-01-01“…Key findings reveal the effects of these nanoparticles (NPs) on hepatic enzymes—Aspartate aminotransferase (AST), Alanine transaminase (ALT), and Alkaline phosphatase (ALP)—and renal function markers, including urea and creatinine levels, under both healthy and pathological conditions. …”
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4148
Approaches and applications in transdermal and transpulmonary gene drug delivery
Published 2025-01-01“…The presence of degrading enzymes, acidic pH conditions, and the gastrointestinal mucus layer pose significant barriers for genetic therapy, necessitating exploration of alternative therapeutic options. …”
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4149
Metagenomic Reveals the Role of Autochthonous <i>Debaryomyces hansenii</i> in the Fermentation and Flavor Formation of Dry Sausage
Published 2025-01-01“…The results showed that inoculation with <i>D. hansenii</i> SH4 promoted volatile compound formation from carbohydrate and amino acid metabolism and accelerated ester synthesis. The enzymes, genes, and microorganisms involved in the formation pathway of volatile compounds based on microbial metabolism were predicted and constructed into a metabolic pathway network. …”
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4150
An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein...
Published 2024-11-01“…_E13-27, which have the oligosaccharide-degradation enzymes genes, including the GH10, GH13, GH43, GH95, and GH115 families. …”
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4151
AIDS Cholangiopathy in an Asymptomatic, Previously Undiagnosed Late-Stage HIV-Positive Patient from Kenya
Published 2011-01-01“…Routine laboratory testing was notable for a hypochromic microcytic anemia, slight leukopenia, and mild hypoalbuminemia. Liver enzymes were all elevated. Deep venous thrombosis was confirmed, and a CT scan of the chest disclosed no pulmonary emboli. …”
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4152
Allelopathic and auto-toxic effects of aqueous extracts of Codonopsis pilosula root secretions.
Published 2025-01-01“…Our findings revealed that the inhibitory effects on seed germination, seedling growth, and the activity of antioxidant enzymes-collectively referred to as a comprehensive effect-intensified progressively with increasing concentrations of the aqueous extracts from C. pilosula root exudates. …”
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4153
A Case of Glycogenic Hepatopathy as a Complication of Poorly Controlled Type 1 Diabetes Mellitus
Published 2022-01-01“…An acute elevation of liver enzymes was noted as the DKA resolved, with the alanine transferase and aspartate transferase levels elevated to more than 50 times the normal limit within the next 24 hours. …”
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4154
Effect of Static Magnetic Field on Oxidant/Antioxidant Parameters in Cancerous and Noncancerous Human Gastric Tissues
Published 2016-01-01“…SMF accelerates peroxidation reactions possibly by suppressing SOD and GSH-Px enzymes in the cancerous gastric tissue. This event caused by SMF might play part in the death of cancer cells, which may be a good supportive vehicle for the cancer therapy.…”
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4155
Maternal Vitamin B12 in Pregnancy and Placental Development
Published 2024-01-01“…Vitamin B12, or cobalamin, is an essential nutrient required for diverse physiological functions secondary to its role as a critical cofactor for two mammalian enzymes, methionine synthase and methylmalonyl-CoA mutase. …”
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4156
Process Optimization for Biosingeing of 100% Cotton Terry Towel Fabric Using Box–Behnken Design
Published 2022-01-01“…Therefore, the purpose of the present study is to treat the fabric with cellulase enzymes to improve the dyeing and finishing quality. …”
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4157
Effectiveness of Polyclonal Antibody Immunoconjugate Treatment with Propamidine Isethionate for Amoebic Keratitis in Golden Hamsters
Published 2023-01-01“…The most used treatment for AK is the combination of propamidine isethionate combined with polyhexamethylene biguanide, which disrupts the cytoplasmic membrane, and damages cellular components and respiratory enzymes. We proposed an immunoconjugate treatment obtained from Acanthamoeba immunized rabbit serum combined with propamidine isethionate; the corneas of hamsters inoculated with A. griffini (MYP2004) were treated with the combined, at 1, 2, and 3 weeks. …”
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4158
The Evolving Role of Endoscopic Retrograde Cholangiography before and after Cholecystectomy
Published 1998-01-01“…The use of preoperative ERC for the indication of abnormal liver enzymes declined (P<0.05), while the yield increased (25% versus 61%, P<0.01). …”
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4159
Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors...
Published 2025-01-01“…Cognitive dysfunction in Alzheimer's disease results from a complex interplay of various pathological processes, including the dysregulation of key enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). …”
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4160
Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.
Published 2025-01-01“…For example, virulent bacterial pathogens have proteins called effectors that are typically enzymes and are secreted into host cells. To detect and respond to the activities of effectors, diverse phyla of host organisms evolved effector-triggered immunity (ETI). …”
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