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  1. 4141

    Comprehensive Analysis of β-1,3-Glucanase Genes in Wolfberry and Their Implications in Pollen Development by Xin Zhang, Pinjie Zheng, Xurui Wen, Zhanlin Bei

    Published 2024-12-01
    “…β-1,3-Glucanases (Glu) are key enzymes involved in plant defense and physiological processes through the hydrolysis of β-1,3-glucans. …”
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  2. 4142

    Role of Lactate in Inflammatory Processes: Friend or Foe by Carolina Manosalva, John Quiroga, John Quiroga, Alejandra I. Hidalgo, Pablo Alarcón, Nicolás Ansoleaga, Nicolás Ansoleaga, María Angélica Hidalgo, Rafael Agustín Burgos

    Published 2022-01-01
    “…Additionally, various targets, including post-translational modifications, G-protein coupled receptor and transcription factor activation such as NF-κB and HIF-1, allow lactate to modulate signaling pathways that control the expression of cytokines, chemokines, adhesion molecules, and several enzymes associated with immune response and metabolism. …”
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  3. 4143

    Unexpectedly life-threatening meal: Contamination by Bongkrekic acid in Taiwan by Ching-Hsiang Yu, En-Chih Liao, Yu-Jang Su

    Published 2025-01-01
    “…On examination, refractory hypotension, jaundice, diffuse abdominal pain, high levels of liver enzymes, metabolic acidosis, coagulopathy, and acute hepatic failure were present. …”
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  4. 4144

    Atom-Driven and Knowledge-Based Hydrolysis Metabolite Assessment for Environmental Organic Chemicals by Zhe Liu, Yufan Lin, Qi He, Lingjie Dai, Qinyan Tan, Binyan Jin, Philip W. Lee, Xiaoming Zhang, Li Zhang

    Published 2025-01-01
    “…The metabolism of environmental organic chemicals often relies on the catalytic action of specific enzymes at the nanoscale, which is critical for assessing their environmental impact, safety, and efficacy. …”
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  5. 4145

    Skeletal Muscle Mitochondria and Aging: A Review by Courtney M. Peterson, Darcy L. Johannsen, Eric Ravussin

    Published 2012-01-01
    “…Animal and human studies typically show that skeletal muscle mitochondria are altered with aging, including increased mutations in mitochondrial DNA, decreased activity of some mitochondrial enzymes, altered respiration with reduced maximal capacity at least in sedentary individuals, and reduced total mitochondrial content with increased morphological changes. …”
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  6. 4146

    Exploration of the Role of Cyclophilins in Established Hepatitis B and C Infections by Jennifer Molle, Sarah Duponchel, Jennifer Rieusset, Michel Ovize, Alexander V. Ivanov, Fabien Zoulim, Birke Bartosch

    Published 2024-12-01
    “…Cyclophilin (Cyp) inhibitors are of clinical interest in respect to their antiviral activities in the context of many viral infections including chronic hepatitis B and C. Cyps are a group of enzymes with peptidyl-prolyl isomerase activity (PPIase), known to be required for replication of diverse viruses including hepatitis B and C viruses (HBV and HCV). …”
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  7. 4147

    Animal-based evidence supports protective activity of bioengineered silver and gold nanomaterials on hepatic and renal function profile parameters by Hamed Barabadi, Hesam Noqani, Maha Soltani, Ayeh Sabbagh Kashani

    Published 2025-01-01
    “…Key findings reveal the effects of these nanoparticles (NPs) on hepatic enzymes—Aspartate aminotransferase (AST), Alanine transaminase (ALT), and Alkaline phosphatase (ALP)—and renal function markers, including urea and creatinine levels, under both healthy and pathological conditions. …”
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  8. 4148

    Approaches and applications in transdermal and transpulmonary gene drug delivery by Anni Zhang, Xuran Zhang, Jiahui Chen, Xianbao Shi, Xijuan Yu, Zhonggui He, Zhonggui He, Jin Sun, Jin Sun, Mengchi Sun, Mengchi Sun, Zhijun Liu

    Published 2025-01-01
    “…The presence of degrading enzymes, acidic pH conditions, and the gastrointestinal mucus layer pose significant barriers for genetic therapy, necessitating exploration of alternative therapeutic options. …”
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  9. 4149

    Metagenomic Reveals the Role of Autochthonous <i>Debaryomyces hansenii</i> in the Fermentation and Flavor Formation of Dry Sausage by Qian Chen, Siyuan He, Mengtong Li, Yumeng Sui, Baohua Kong, Rongxin Wen

    Published 2025-01-01
    “…The results showed that inoculation with <i>D. hansenii</i> SH4 promoted volatile compound formation from carbohydrate and amino acid metabolism and accelerated ester synthesis. The enzymes, genes, and microorganisms involved in the formation pathway of volatile compounds based on microbial metabolism were predicted and constructed into a metabolic pathway network. …”
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  10. 4150
  11. 4151

    AIDS Cholangiopathy in an Asymptomatic, Previously Undiagnosed Late-Stage HIV-Positive Patient from Kenya by Yiming Gao, Kathryn Chin, Yehia Y. Mishriki

    Published 2011-01-01
    “…Routine laboratory testing was notable for a hypochromic microcytic anemia, slight leukopenia, and mild hypoalbuminemia. Liver enzymes were all elevated. Deep venous thrombosis was confirmed, and a CT scan of the chest disclosed no pulmonary emboli. …”
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  12. 4152

    Allelopathic and auto-toxic effects of aqueous extracts of Codonopsis pilosula root secretions. by Daiyu Qiu, Xue Wang, Fengbin Xu, Qian Li, Fengying Ren, Kan Jiang

    Published 2025-01-01
    “…Our findings revealed that the inhibitory effects on seed germination, seedling growth, and the activity of antioxidant enzymes-collectively referred to as a comprehensive effect-intensified progressively with increasing concentrations of the aqueous extracts from C. pilosula root exudates. …”
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  13. 4153

    A Case of Glycogenic Hepatopathy as a Complication of Poorly Controlled Type 1 Diabetes Mellitus by Samhitha Munugoti, Vamsee Reddy, Gaurav Patel, Maneesh Gaddam, Triveni Abburi

    Published 2022-01-01
    “…An acute elevation of liver enzymes was noted as the DKA resolved, with the alanine transferase and aspartate transferase levels elevated to more than 50 times the normal limit within the next 24 hours. …”
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  14. 4154

    Effect of Static Magnetic Field on Oxidant/Antioxidant Parameters in Cancerous and Noncancerous Human Gastric Tissues by Bahadır Öztürk, Zahide Esra Durak, Süleyman Büber, Ender Hilmi Kocaoğlu

    Published 2016-01-01
    “…SMF accelerates peroxidation reactions possibly by suppressing SOD and GSH-Px enzymes in the cancerous gastric tissue. This event caused by SMF might play part in the death of cancer cells, which may be a good supportive vehicle for the cancer therapy.…”
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  15. 4155

    Maternal Vitamin B12 in Pregnancy and Placental Development by Amrita Arcot, Rachel E. Walker, Kelly Gallagher, Kevin C. Klatt, Alison D. Gernand

    Published 2024-01-01
    “…Vitamin B12, or cobalamin, is an essential nutrient required for diverse physiological functions secondary to its role as a critical cofactor for two mammalian enzymes, methionine synthase and methylmalonyl-CoA mutase. …”
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  16. 4156

    Process Optimization for Biosingeing of 100% Cotton Terry Towel Fabric Using Box–Behnken Design by Aklilu Azanaw, Asnake Ketema

    Published 2022-01-01
    “…Therefore, the purpose of the present study is to treat the fabric with cellulase enzymes to improve the dyeing and finishing quality. …”
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  17. 4157

    Effectiveness of Polyclonal Antibody Immunoconjugate Treatment with Propamidine Isethionate for Amoebic Keratitis in Golden Hamsters by Manuel Enrique Ávila-Blanco, Sandra Lizbeth Aguilera-Martínez, Javier Ventura-Juarez, Jorge Pérez-Serrano, Elizabeth Casillas-Casillas, Luis Fernando Barba-Gallardo

    Published 2023-01-01
    “…The most used treatment for AK is the combination of propamidine isethionate combined with polyhexamethylene biguanide, which disrupts the cytoplasmic membrane, and damages cellular components and respiratory enzymes. We proposed an immunoconjugate treatment obtained from Acanthamoeba immunized rabbit serum combined with propamidine isethionate; the corneas of hamsters inoculated with A. griffini (MYP2004) were treated with the combined, at 1, 2, and 3 weeks. …”
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  18. 4158

    The Evolving Role of Endoscopic Retrograde Cholangiography before and after Cholecystectomy by SC Ganguli, TM Pasha, BT Petersen

    Published 1998-01-01
    “…The use of preoperative ERC for the indication of abnormal liver enzymes declined (P<0.05), while the yield increased (25% versus 61%, P<0.01). …”
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  19. 4159

    Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors... by Fatima Zahra Guerguer, Bouchra Rossafi, Oussama Abchir, Yasir S Raouf, Dhabya Bakhit Albalushi, Abdelouahid Samadi, Samir Chtita

    Published 2025-01-01
    “…Cognitive dysfunction in Alzheimer's disease results from a complex interplay of various pathological processes, including the dysregulation of key enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). …”
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  20. 4160

    Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity. by Haleema Sadia Malik, James B Bliska

    Published 2025-01-01
    “…For example, virulent bacterial pathogens have proteins called effectors that are typically enzymes and are secreted into host cells. To detect and respond to the activities of effectors, diverse phyla of host organisms evolved effector-triggered immunity (ETI). …”
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