Current Review of Genetically Modified Lactic Acid Bacteria for the Prevention and Treatment of Colitis Using Murine Models by Alejandra de Moreno de LeBlanc, Silvina del Carmen, Jean-Marc Chatel, Anderson Miyoshi, Vasco Azevedo, Philippe Langella, Luis G. Bermúdez-Humarán, Jean Guy LeBlanc

“…Then, the two principally studied strategies are discussed (i) GM-LAB producing antioxidant enzymes and (ii) GM-LAB producing the anti-inflammatory cytokine IL-10. …”
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Liver Transplantation for Acute Liver Failure at 11-Week Gestation with Successful Maternal and Fetal Outcome by Vinaya C. Maddukuri, Courtney D. Stephenson, Lon Eskind, William A. Ahrens, Preston Purdum, Mark W. Russo

“…Pregnancy-specific liver conditions like hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome and acute fatty liver of pregnancy can cause ALF at term or postpartum, but, typically occur during the third trimester. …”
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N-acetylcysteine use in a cocaine-induced liver failure: a case report by Vanessa Biering, Ronan Bellouard, Ronan Bellouard, Maëlle Martin, Éric Dailly, Éric Dailly, Catherine Monteil-Ganière, Edouard Charles Le Carpentier

“…In addition to a sharp rise in her liver enzymes, the patient also presented metabolic acidosis, renal failure, and rhabdomyolysis. …”
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Challenges in Treating Statin-Associated Necrotizing Myopathy by Patrick Webster, Nicholas Wiemer, Abdalhamid Al Harash, Cody Marshall, Nazia Khatoon, Michael Lucke

“…Myalgia and mild elevation in muscle enzymes are common side effects of statin therapy. …”
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Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy by Anna Piscone, Francesca Gorini, Susanna Ambrosio, Anna Noviello, Giovanni Scala, Barbara Majello, Stefano Amente

“…Central to this pathway are enzymes like 8-oxoguanine glycosylase 1 (OGG1), which recognize and excise 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) lesions, thereby initiating a series of repair processes that restore DNA integrity. …”
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Effects of vitamin C on cardiovascular oxidative stress induced by hypothyroidism in neonatal and juvenile rats by Farimah Beheshti, Reza Mohebbati, Mahmoud Hosseini, Saeed Niazmand, Masomeh Mirzaei, Mahdiyeh Hedayati-Moghadam, Maryam Paseban

“…Results: In the group receiving PTU, levels of thyroxine and antioxidant enzymes were decreased in serum, heart, and aortic tissues. …”
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Bio-hydrogen Production Using Modified Zeolite Decorated with Green Iron Oxide Nanoparticles During the Fermentation Process from Food Industry Wastewater by Elahe Mansouri, Mohammad Hossein Sayadi, Nazanin Fahoul

“…These results show that nanoparticles at specific concentrations enhance bacterial activity by affecting intracellular enzymes, thereby improving efficiency. Consequently, the green synthesis of Fe3O4/ZSM-5 nanoparticles and the dark fermentation process have great potential for biohydrogen production from industrial food wastewater.…”
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Frugal method for extracting DNA from saliva suitable for low-budget labs and usable in PCR assays by Kamar Shayah, Joseph Shenekji, Lana Karnoub, Sana Wohbeh, Hagar Hamsho

“…The suggested frugal method relies on providing a new solution for extracting DNA from human saliva without the need for enzymes or high grade reagents or columns, which makes suitable for low budget laboratories in developing countries to manufacture it locally, it uses a phase separation with technical skills to extract the DNA from the saliva achieving safety by not using hazardous reagents, and it is a sustainable eco-friendly method that gives decent yield of good quality DNA in ~20 minutes to be used in PCR applications with a cost that is estimated to be 10 times cheaper than current used methods.…”
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A Genomic Approach to Study Anthocyanin Synthesis and Flower Pigmentation in Passionflowers by Lilian Cristina Baldon Aizza, Marcelo Carnier Dornelas

“…The obtained sequences code for putative enzymes are involved in the production of flavonoid precursors, as well as those involved in the formation of particular (“decorated”) anthocyanin molecules. …”
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Exploring the Crosstalk between Inflammation and Epithelial-Mesenchymal Transition in Cancer by Indranil Chattopadhyay, Rangarao Ambati, Rohit Gundamaraju

“…Tumor cells undergo invasion and metastasis through epithelial-to-mesenchymal cell transition (EMT) by activation of alterations in extracellular matrix (ECM) protein-encoding genes, enzymes responsible for the breakdown of ECM, and activation of genes that drive the transformation of the epithelial cell to the mesenchymal type. …”
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Research Progress on Enzymatic Preparation and Functional Properties of Bioactive Peptides in Hairtail by Yuanyuan WU, Kewei ZHENG, Wenzhu LI, Cheng LI, Xiaojun YAN, Qingbao MA, Wei JIANG

“…The antioxidative activity of enzymatic hydrolysates is extensively studied, with alkaline protease and papain being the most commonly used enzymes. However, research on the specific peptide sequences responsible for bioactivity and their underlying mechanisms remains limited. …”
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Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes by Jun Sumaoka, Hiroki Akiba, Makoto Komiyama

“…Furthermore, the activities of various inhibitors on these enzymes are quantitatively evaluated, indicating a strong potential of the method for efficient screening of eminent inhibitors from a number of candidates.…”
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Short-term high-fat diet post-ACLT surgery activates chondrocyte AMPK pathway and slows articular cartilage degeneration in rats by Hongri Ruan, Tingting Zhu, Tianwen Ma, Yun Liu, Jiasan Zheng

“…In vitro experiments reveal that low concentrations of FFAs stimulate chondrocyte proliferation and energy metabolism, whereas AMPK inhibition leads to elevated expression of inflammatory mediators and ECM-degrading enzymes in chondrocytes. Collectively, these results suggest that short-term HFD following ACLT surgery exerts protective effects on cartilage, primarily through AMPK activation.…”
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Phenolic Compounds and Anthocyanins in Legumes and Their Impact on Inflammation, Oxidative Stress, and Metabolism: Comprehensive Review by Rocio Guadalupe Hernández-Ruiz, Xochitl Citalli Olivares-Ochoa, Yahatziri Salinas-Varela, David Guajardo-Espinoza, Luis Gustavo Roldán-Flores, Edgar Alfonso Rivera-Leon, Andres López-Quintero

“…They also exert anti-inflammatory effects by inhibiting proinflammatory enzymes and cytokines. Additionally, anthocyanins and phenolics may positively influence the gut microbiome, indirectly affecting metabolism and inflammation.…”
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The Dynamic DNA Demethylation during Postnatal Neuronal Development and Neural Stem Cell Differentiation by Huikang Tao, Pei Xie, Yuhang Cao, Liqi Shu, Liping Li, Junchen Chen, Guangfeng Tian, Yingliang Zhuang, Qiang Shu, Xuekun Li

“…In this study, utilizing DNA dot blot, immunofluorescence staining, and qRT-PCR, we studied the expression pattern of Tets, the enzymes governing DNA demethylation, and the levels of 5hmC, 5fC, and 5caC during the postnatal neuronal development of mice. …”
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Synthesis and characterization of allomelanin model from 1,8-dihydroxynaphthalene autooxidation by Jan Pukalski, Krystian Mokrzyński, Marek Chyc, Marek J. Potrzebowski, Tomasz Makowski, Mateusz Dulski, Dariusz Latowski

“…The proposed synthesis protocol is simple and cost-effective with no enzymes or catalysts needed. The final product is not adsorbed on any surface, since the pigment is the result of autooxidation of 1,8-dihydroxynaphthalene. …”
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Influence of Mast Cells in Drug-Induced Gingival Overgrowth by Tamilselvan Subramani, Vidhya Rathnavelu, Swee Keong Yeap, Noorjahan Banu Alitheen

“…The development of antibodies to MC-specific enzymes, tryptase and chymase, has facilitated the study of mast cells in DIGO. …”
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Association between microplastics and the functionalities of human gut microbiome by Bei Gao, Lixia Chen, Lizhi Wu, Shirui Zhang, Sunan Zhao, Zhe Mo, Zhijian Chen, Pengcheng Tu

“…Associations were found between microplastics and microbial species, as well as microbial genes encoding invasion-related virulence factors, quorum sensing, autoinducer and transporter system, and microplastic biodegradation enzymes. The findings are of significance to improve the understanding of functional changes in the gut microbiome associated with microplastic exposure, as well as raising awareness regarding the health risks of microplastics in the human population.…”
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Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway by Liwei Wu, Qinghui Zhang, Weiqi Dai, Sainan Li, Jiao Feng, Jingjing Li, Tong Liu, Shizan Xu, Wenwen Wang, Xiya Lu, Qiang Yu, Kan Chen, Yujing Xia, Jie Lu, Yingqun Zhou, Xiaoming Fan, Chuanyong Guo

“…The expression levels of liver enzymes, inflammatory cytokines, and other marker proteins were determined at 2, 8, and 24 hours after IR. …”
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A Young Male with Severe Myocarditis and Skeletal Muscle Myositis by Abdalla Ibrahim, Eoghan Meagher, Alexander Fraser, Thomas J. Kiernan

“…He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI) confirmed active myocarditis with extensive myocardial fibrosis and normal left ventricular ejection fraction (LVEF). …”
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