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4081
Pharmacokinetic evaluation of the interaction between oral kaempferol and ethanol in rats
Published 2016-12-01“…Increased permeability of cell membrane and ethanolkaempferol interactions on CYP450 enzymes may enhance the oral bioavailability of kaempferol in rats.…”
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4082
Impact of trace metal supplementation on anaerobic biological methanation under hydrogen and carbon dioxide starvation
Published 2025-01-01“…Conversely, bacteria were plastic and prone to genetic fluctuations, accumulating mutations on genes encoding for ABC-transporters and C-metabolism enzymes. This study pioneers cellular resilience and response to micronutrient supplementation in anaerobic carbon dioxide-fixating microbiomes, offering valuable insights into microbial activity recovery after carbon and electron donor deprivation.…”
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4083
Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids
Published 2012-01-01“…Epoxyeicosatrienoic acids (EETs) are generated by the activity of both selective and also more general cytochrome p450 (CYP) enzymes on arachidonic acid and inactivated largely by soluble epoxide hydrolase (sEH), which converts them to their corresponding dihydroxyeicosatrienoic acids (DHETs). …”
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4084
Epigenetics and Shared Molecular Processes in the Regeneration of Complex Structures
Published 2016-01-01“…This review provides an overview of known contributions to regenerative processes by noncoding RNAs and chromatin-modifying enzymes involved in epigenetic regulation.…”
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4085
Synergistic Effects of Cinnamomum verum and Stingless Bee Honey on Isoproterenol-induced Cardiac Hypertrophic Murine Model
Published 2024-12-01“…CH was characterized by electrocardiography, hypertrophic indices, and biochemical estimations such as total glucose, protein, albumin, lipid profiles, cardiac marker enzymes, and histopathological studies. Results: Rats received ISO had increased levels of glucose, protein, cholesterol, triglycerides, very low-density lipoprotein, and low-density lipoprotein, coupled with decreased levels of albumin and high-density lipoprotein. …”
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4086
Prokaryotic cellulase gene clusters derived from 2,305 metagenomes
Published 2025-02-01“…They do it by producing cellulases, the various enzymes which break beta-glycosidic bonds in the cellulose. …”
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4087
Pantoprazole – safety in drug-drug interaction
Published 2012-09-01“…Pantoprazole is metabolized by CYP2C19 and CYP3A4, however, it has the lowest affinity to these enzymes of all PPIs. The primary metabolite of pantoprazole (the CYP system product 4-hydroxypantoprazole) enters next cytosolic phase of biotransformation i.e. conjugation to sulfate. …”
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4088
The Neurometabolic Function of the Dopamine–Aminotransferase System
Published 2025-01-01“…Results: The dopamine–aminotransferase system of the energy metabolism regulation is a separate, independent, regulatory and diagnostically significant biochemical pathway controlled by the hormonal system, the key hormone is cortisol, the key neurotransmitter is dopamine, the key transcription factor is CREB, and the key regulatory enzymes are alanine aminotransferase, aspartate aminotransferase, and tyrosine aminotransferase. …”
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4089
Determination of lipid peroxidation biomarkers in vero cell line inoculated with bovine ephemeral fever virus
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4090
Study protocol on the impact of postnatal maternal separation stress on dental enamel formation in a murine experimental model.
Published 2024-01-01“…Histological and molecular analyses-such as immunohistochemistry, indirect immunofluorescence, and in situ zymography-will be performed to evaluate possible changes in proteins and enzymes that are essential for proper enamel biomineralization.…”
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4091
Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer
Published 2006-01-01“…<emph>Results</emph>. (1) The spatial distribution of the three leading enzymes in arachidonic acid pathway—cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1—followed sequential arrangement in Crohn's ulcer: neutrophils highly expressing 5-lipoxygenase were in the utmost surface which bordered the band of cyclooxygenase-2 expression that is located just beneath it, and in the lower layers and below the granulation region were eosinophils carrying 15-lipoxygeanse-1. (2) Cyclooxygenase-2 and 15-Lipoxygenase-1-positive cells formed two barrier-like structures that possibly inhibited neutrophil infiltration. …”
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4092
Giant Water Bugs, Electric Light Bugs, Lethocerus, Abedus, Belostoma (Insecta: Heteroptera: Belostomatidae)
Published 2005-02-01“…Individuals prey on aquatic insects, small fish, frogs, tadpoles, small birds, and other organisms they are able to capture. Powerful enzymes are injected into prey to kill them. Adults of Lethocerus are considered a delicacy in Asia, and are eaten both fresh and cooked. …”
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4093
Effects of Breakpoint Changes on Carbapenem Susceptibility Rates ofEnterobacteriaceae: Results from the SENTRY Antimicrobial Surveillance Program, United States, 2008 to 2012
Published 2014-01-01“…Very few of these Enterobacteriaceae produce carbapenamase enzymes; therefore, the clinical significance of these changes has not yet been clearly determined. …”
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4094
Glycerol Carbonate: A Novel Biosolvent with Strong Ionizing and Dissociating Powers
Published 2012-01-01“…The activity of biocatalysts in nonaqueous solvents is related to the interaction of organic solvents with cells or enzymes. The behavior of proteins is strongly dependent on the protonation state of their ionizable groups, which ionization constants are greatly affected by the solvent. …”
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4095
Long-term Outcomes (10 years) of Hepatic Transplantation in a Patient with Hepatic Adenomatosis: A Case Report
Published 2024-12-01“…This study reports a case of an 18-year-old woman with perturbed liver function enzymes and multiple hepatic nodules. She had no significant medical history, chronic liver disease, or diabetes and was not taking any regular medications or anabolic steroids. …”
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4096
Metalloproteinase Inhibitors: Status and Scope from Marine Organisms
Published 2010-01-01“…Metalloproteinases, especially, matrix metalloproteinases (MMPs) are a class of structurally similar enzymes that contribute to the extracellular matrix degradation and play major role in normal and pathological tissue remodeling. …”
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4097
Black Pepper’s Anti-Aging and Chemoprevention Properties: A Review
Published 2023-12-01“…Overall, the anti-aging properties of black pepper and its constituents are exhibited through several pathways, including senescence prevention, antioxidant protection, control of ROS levels, and the inhibition of aging-related enzymes. Additionally, cell cycle regulation, antiangiogenic and anti-metastatic action, apoptosis induction, and the suppression of carcinogenesis are some of the mechanisms utilized in cancer prevention activities. …”
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4098
Foliar Application of Copper Oxide Nanoparticles Increases the Photosynthetic Efficiency and Antioxidant Activity in Brassica juncea
Published 2022-01-01“…Among different concentrations of CuO NPs (0, 2, 4, 8, and 16 mg/L), 8 mg/L proved to be the optimum foliar spray treatment and increase the chlorophyll content, net photosynthetic rate, leaf proline content, and antioxidant enzymes activity. We concluded that CuO NPs interact with meristematic cells triggering biochemical pathways conductive to an enhancement of the growth attributes. …”
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4099
Unraveling the metabolic landscape of Exophiala spinifera strain FM: Model reconstruction, insights into biodesulfurization and beyond.
Published 2025-01-01“…However, the specific pathway and enzymes involved in this process remain unclear due to limited genome sequencing and metabolic understanding of E. spinifera. …”
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4100
Biological Processes that Prepare Mammalian Spermatozoa to Interact with an Egg and Fertilize It
Published 2012-01-01“…The hydrolytic action of the acrosomal enzymes released, along with the hyperactivated beat pattern of the bound spermatozoon, is important factor that directs the sperm to penetrate the egg coat and fertilize the egg. …”
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