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4061
Antibacterial Effect of Black Pepper Petroleum Ether Extract against Listeria monocytogenes and Salmonella typhimurium
Published 2019-01-01“…The activities of key metabolic enzymes shed some light on the biochemical mechanism of aglycon cell growth inhibition, indicating that the energetic metabolism of L. monocytogenes and S. typhimurium was markedly influenced by the BPPE. …”
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4062
Insights into microbiota community dynamics and flavor development mechanism during golden pomfret (Trachinotus ovatus) fermentation based on single-molecule real-time sequencing a...
Published 2024-01-01“…Volatile profiles resulted from the interactions among the microorganisms and derived enzymes, with the main metabolic pathways being amino acid biosynthesis/metabolism, carbon metabolism, and glycolysis/gluconeogenesis. …”
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4063
Frequency of Drug Resistance Gene Amplification in Clinical Leishmania Strains
Published 2010-01-01“…Amplified genes code for adenosine triphosphate-dependent transporters (multidrug resistance and P-glycoproteins P), enzymes involved in trypanothione pathway, particularly gamma glutamyl cysteine synthase, and others involved in folates metabolism, such as dihydrofolate reductase and pterine reductase. …”
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4064
DIA-based quantitative proteomic analysis on porcine meat quality at different chilling rates
Published 2024-09-01“…These pathways indicated that VFC delayed cell metabolism and glycolysis by down-regulating the expression of metabolic enzymes. The tenderness was improved by up-regulating the expression of proteasome and m-calpain.…”
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4065
Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis
Published 2016-08-01“…Hyperamilasemia, premature intralobular activation of digestive enzymes, accumulation of large vacuoles in acinar cells, activation of proinflammatory mediators, apoptosis and necrosis of acinar cells are the basic pathomorphological signs of AP. …”
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4066
Antin-diabetic cognitive dysfunction effects and underpinning mechanisms of phytogenic bioactive peptides: a review
Published 2025-01-01“…We found that plant-derived active peptides alleviate diabetic cognitive impairment by inhibiting key enzymes (e.g., α-glucosidase, α-amylase) to improve blood glucose levels and increase antioxidant activity, modulate inflammatory mediators, and address intestinal dysbiosis. …”
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4067
Microbiota-derived β carotene is required for strobilation of Aurelia aurita by impacting host retinoic acid signaling
Published 2025-02-01“…Transcriptional analysis revealed that beta carotene and 9-cis RA restored expression of strobilation genes in sterile polyps to native levels. Inhibition of key enzymes in the RA pathway disrupted strobilation, further confirming its importance. …”
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4068
Targeting the kynurenine pathway: another therapeutic opportunity in the metabolic crosstalk between cancer and immune cells
Published 2025-01-01“…In this review, we revisit current advances, explore future directions, and emphasize the importance of dual inhibition of the KP rate-limiting enzymes IDO1 and tryptophan 2,3-dioxygenase-2 (TDO2) in appropriate patient populations. …”
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4069
Strategies to improve the quality of wheat flour in baking: a review
Published 2025-02-01“…Focusing on gluten, which is crucial for the technological quality of the flour, we explored strategies involving additives (oxidizing agents, emulsifiers, and hydrocolloids), processing aids (enzymes), and the ingredient vital wheat gluten. We also evaluated the regulatory aspects governing the use of these enhancers in various countries.…”
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4070
A Curious Case of Iron-Deficiency Anemia
Published 2016-01-01“…Laboratory results showed hemoglobin of 47 g/L, MCV of 80 fL, and ferritin of 6 ng/mL. Liver enzymes and liver function tests were normal. Abdominal ultrasound showed a cirrhotic liver with splenomegaly and varices suggestive of portal hypertension. …”
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4071
Prolonged Serum Alanine Aminotransferase Elevation Associated with Isotretinoin Administration
Published 2019-01-01“…When oral isotretinoin was readministered for intractable facial acne 3 years later, liver enzymes remained normal throughout the course of therapy. …”
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4072
Sirtuin 1: A Dilemma in Transplantation
Published 2020-01-01“…Sirtuin 1, a member of sirtuin family of histone deacetylase enzymes, has been implicated in a variety of physiologic and pathologic events, including energy metabolism, cell survival, and age-related alterations. …”
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4073
COFcap2, a recyclable tandem catalysis reactor for nitrogen fixation and conversion to chiral amines
Published 2025-01-01“…Importantly, the COFcap-2 system is recycled 15 times with retention of performance, addressing the relative instability and poor recyclability of enzymes that has hindered their broad implementation for energy-efficient, low waste production of chemicals and (bio)pharmaceuticals.…”
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4074
α-Glucosidase inhibitor produced by an endophytic fungus, Xylariaceae sp. QGS 01 from Quercus gilva Blume
Published 2017-06-01“…QGS 01, an endophytic fungus isolated from the stem of Quercus gilva Blume showed high α-glucosidase inhibitory activity. α-Glucosidase inhibitor have the role as one of carbohydrate-hydrolyzing enzymes to postpone absorption of glucose in the digestive organs. …”
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4075
A Review of Marine Bacterial Intracellular and Extracellular Bioactive Compounds as Novel Antibacterial and Anti-Inflammation Agents
Published 2025-01-01“…A crucial resource in the ongoing search for novel peptides, proteins, lipids, nucleosides, enzymes, alkaloids, polyketides, and terpenoids is the diversity of marine bacterium strains. …”
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4076
Sleeve gastrectomy reveals the plasticity of the human gastric epithelium
Published 2025-01-01“…Using histology, and single-cell RNA sequencing of the gastric epithelium in 12 women, we observed that SG is associated with an increase in a sub-population of acid-secreting parietal cells that overexpress respiratory enzymes and an increase in histamine-secreting enterochromaffin-like cells (ECLs). …”
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4077
Paliperidone Inducing Concomitantly Syndrome of Inappropriate Antidiuretic Hormone, Neuroleptic Malignant Syndrome, and Rhabdomyolysis
Published 2016-01-01“…On the third day, he developed high grade fever and severe muscle rigidity with raised creatine phosphokinase (CPK) and liver enzymes levels. He was treated with dantrolene 100 mg, bromocriptine 2.5 mg, and lorazepam 2 mg. …”
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4078
Effect of Activation Energy on Magnetized Couple Stress Fluid over an Inclined Stretching Permeable Cylinder
Published 2025-05-01“…Activation energy is of considerable significance in diverse applications such as chemical kinetics, catalyst development, enzymes, semiconductors, and systems sensitive to temperature, such as chemical reactors and engines. …”
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4079
Women's Experiences of Preeclampsia: Australian Action on Preeclampsia Survey of Women and Their Confidants
Published 2011-01-01“…Respondents reported experiencing pre-eclampsia (n=53), eclampsia (n=5), and/or Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP syndrome) (n=26). …”
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4080
Prenatal exposure to bisphenol A causes reproductive damage in F1 male rabbits due to inflammation and oxidative stress
Published 2025-01-01“…By modulation of the Nrf2 and NF-κB axes, BPA could influence the expression of antioxidant enzymes and inflammatory mediators in the rabbit reproductive system, leading to cell apoptosis and tissue damage. …”
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