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3921
Valorisation of shell waste of invasive crayfish from Danube River (Faxonius limosus): Protein extraction and characterization
Published 2024-01-01“…The first method involved using naturally present enzymes (proteases and lipases) in crayfish wastes to recover proteins through an autolysis process. …”
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3922
Bilateral Glaucoma as Possible Additional Feature for PGAP3-Associated Hyperphosphatasia
Published 2024-01-01“…Hyperphosphatasia with mental disorder (HPMRS) is a rare autosomal recessive disease caused by gene mutations in enzymes involved in the synthesis and remodeling of lipids. …”
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3923
Microbiology of Ethiopian Traditionally Fermented Beverages and Condiments
Published 2020-01-01“…Traditional fermented beverage and condiment products have essential vitamins, minerals, enzymes, and antioxidants that are all enhanced through the process of traditional fermentation practices. …”
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3924
Biomimetic Approach to CO2 Reduction
Published 2018-01-01“…The determination of these characteristics is of interest both for clarifying aspects of the catalytic cycle of natural enzymes that are still unknown and for developing synthetic molecular catalysts that can readily be applied to artificial photosynthetic devices.…”
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3925
The Mitochondrial Disulfide Relay System: Roles in Oxidative Protein Folding and Beyond
Published 2013-01-01“…Their precise functions have been elucidated in molecular detail for the yeast and human enzymes in vitro and in intact cells. However, we still lack knowledge on how Mia40 and Erv1/ALR impact cellular and organism physiology and whether they have functions beyond their role in disulfide bond formation. …”
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3926
L-Ascorbic Acid: A Multifunctional Molecule Supporting Plant Growth and Development
Published 2013-01-01“…Ascorbic acid functions as a major redox buffer and as a cofactor for enzymes involved in regulating photosynthesis, hormone biosynthesis, and regenerating other antioxidants. …”
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3927
Substrates, regulation, cellular functions, and disease associations of P4-ATPases
Published 2025-01-01“…This process generates and regulates transbilayer lipid asymmetry. These enzymes are conserved across all eukaryotes, and the human genome encodes 14 distinct P4-ATPases. …”
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3928
Murine Leukemia Viruses: Objects and Organisms
Published 2011-01-01“…These are the Gag polyprotein, which is the structural protein of a retrovirus particle, the Pol protein, comprising the three retroviral enzymes—protease, which catalyzes the maturation of the particle, reverse transcriptase, which copies the viral RNA into DNA upon infection of a new host cell, and integrase, which inserts the DNA into the chromosomal DNA of the host cell, and the Env polyprotein, which induces the fusion of the viral membrane with that of the new host cell, initiating infection. …”
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3929
A Survey of Mycotoxin Contamination in Fermented Condiments and the Biological Methods for Its Reduction
Published 2025-01-01“…This article summarizes the current status of mycotoxin contamination in fermented condiments, with a focus on mycotoxin-degrading strains from different sources and mycotoxin-degrading enzymes in microbial cells in order to offer insights for reducing harmful fungi and mycotoxin contamination in fermentation condiments.…”
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3930
Peroxisome Proliferator-Activated Receptor and Retinoic X Receptor in Alcoholic Liver Disease
Published 2009-01-01“…Several ethanol metabolizing enzymes are potently regulated by RXR and PPAR𝛼 after alcohol consumption. …”
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3931
Epigenetic Reprogramming of Muscle Progenitors: Inspiration for Clinical Therapies
Published 2016-01-01“…In particular we focus on the current understanding of the epigenetic networks that regulate differentiation of muscle progenitors by the concerted action of chromatin-modifying enzymes and noncoding RNAs. The novel exciting role of exosome-bound microRNA in mediating epigenetic information transfer is also discussed. …”
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3932
Exploring Marine Cyanobacteria for Lead Compounds of Pharmaceutical Importance
Published 2012-01-01“…They produce a large variety of bioactive compounds, including substances with anticancer and antiviral activity, UV protectants, specific inhibitors of enzymes, and potent hepatotoxins and neurotoxins. …”
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3933
Histone Acetylation in the Epigenetic Regulation of Bone Metabolism and Related Diseases
Published 2021-01-01“…Some acetylation-related therapy methods of bone diseases based on metabolic regulation or epigenetic enzymes were also reviewed.…”
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3934
The Low Temperature Induced Physiological Responses of Avena nuda L., a Cold-Tolerant Plant Species
Published 2013-01-01“…Cold stress also leads to changes of some protected enzymes such as peroxidase (POD), superoxide dismutase (SOD), and catalase (CAT). …”
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3935
PPARα as a Transcriptional Regulator for Detoxification of Plant Diet-Derived Unfavorable Compounds
Published 2012-01-01“…A detailed analysis of this observation revealed that PPARα is involved in the metabolism of toxic compounds from plants as well as endobiotic substrates by inducing phase I and phase II detoxification enzymes. PPARα plays a vital role in direct or indirect activation of the relevant genes via the complex network among other xenobiotic nuclear receptors. …”
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3936
The state of the art in anti-aging: plant-based phytochemicals for skin care
Published 2025-01-01“…Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP-2) linked to aging. …”
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3937
The Mechanisms of Action of Interleukin-1 on Rabbit Intestinal Epithelial Cells
Published 1999-01-01“…To identify the signal transduction pathway(s) involved in IL-1's action, cells were treated with IL-1 and the levels of cyclooxygenase (COX) enzymes, prostaglandin E2 (PGE2) and phospholipase A2-activating protein (PLAP), and the activity of phospholipase A2 (PLA2) were measured. …”
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3938
Case Report: Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C
Published 2012-01-01“…The safety was good with no adverse events and maintenance, during a six-month followup, of normal liver enzymes. These data suggest a good safety profile of tocilizumab in patients with rheumatoid arthritis and chronic hepatitis C virus pathology.…”
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3939
PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways
Published 2012-01-01“…The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. …”
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3940
An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024)
Published 2025-01-01“…These derivatives interact with critical biological targets such as enzymes, receptors, and signaling pathways, offering promising avenues for treating complex diseases like cancer and infectious diseases. …”
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