Desmoplasia in Pancreatic Cancer. Can We Fight It? by E. E. Merika, K. N. Syrigos, M. W. Saif

“…Herein we discuss such new developments to fight the desmoplastic reaction, including inhibitors of the epidermal growth factor, fibroblast growth factor, the hedgehog pathway, as well as new molecular targets like CD40 agonist and its effects on T cells, extracellular matrix modifying enzymes such as LOXL2 inhibitor and novel tumour penetrating peptides for delivery of drugs.…”
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Black fungi and ants: a genomic comparison of species inhabiting carton nests versus domatia by Yu Quan, Nickolas Menezes da Silva, Bruna Jacomel Favoreto de Souza Lima, Sybren de Hoog, Vania Aparecida Vicente, Veronika Mayer, Yingqian Kang, Dongmei Shi

“…General genomic characteristics, CYP genes, carbohydrate-active enzymes (CAZymes), secondary metabolism, and sex-related genes were included in the study.…”
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Glycoconjugates and Related Molecules in Human Vascular Endothelial Cells by Norihiko Sasaki, Masashi Toyoda

“…In this paper, we consider the expression and functional roles of endogenous glycoconjugates and related molecules (galectins and glycan-degrading enzymes) in human ECs.…”
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Copper-instigated modulatory cell mortality mechanisms and progress in kidney diseases by Xiya Ren, Limei Zhao, Yajie Hao, Xiu Huang, Guangna Lv, Xiaoshuang Zhou

“…Copper is a vital cofactor in various enzymes, plays a pivotal role in maintaining cell homeostasis. …”
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Sepsis, leukocytes, cytokines and disseminated intravascular coagulation by Ramazan Çöl, Zafer Durgun

“…Various pathogenic effects thai occur in sepsis are attributed to the release of oxygen radicals and enzymes from neutrophils. This review present information about leukocytes and their important roles in sepsis.…”
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Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus by Bikash Adhikari

“…., alkaloids, show antidiabetic activity through the inhibition of enzymes (α-amylase, α-glucosidase, aldose reductase, dipeptidyl peptidase-IV, and protein tyrosine phosphatase-1B); inhibition of advanced glycation end products; increment of insulin secretion and its sensitivity; enhancement of glucose uptake; and their antioxidant ability. …”
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An Overview of DNA Repair in Amyotrophic Lateral Sclerosis by Fabio Coppedè

“…Increasing evidence supports mitochondrial dysfunction and oxidative DNA damage in ALS motor neurons. Several DNA repair enzymes are activated following DNA damage to restore genome integrity, and impairments in DNA repair capabilities could contribute to motor neuron degeneration. …”
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Biochemistry of the Phagosome: The Challenge to Study a Transient Organelle by Oliver Nüsse

“…Intracellular granules or lysosomes of the phagocyte fuse with the phagosome and liberate their destructive enzymes. This process of phagocytosis efficiently protects against most infections; however, some microorganisms avoid their destruction and cause severe damage. …”
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Characterization of Pseudomonas Species Isolated from the Rhizosphere of Plants Grown in Serozem Soil, Semi-Arid Region of Uzbekistan by Dilfuza Egamberdiyeva

“…These strains produced enzymes, phytohormone auxin (IAA), and were antagonist against plant pathogenic fungi in in vitro experiments. …”
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Fish Oil in the Treatment of Ulcerative Colitis by C Ó'Moráin, A Tobin, T McColl, Y Suzuki

“…EPA is a good substrate for lipoxygenase enzymes and is efficiently converted to leukotriene 85, which is less biologically active. …”
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Nonalcoholic Fatty Liver Disease: A Clinical Approach and Review by Maitreyi Raman, Johane Allard

“…Nonalcoholic fatty liver disease (NAFLD) is the most common cause of incidental elevation of liver enzymes in North America and Europe. Risk factors for NAFLD include body mass index of 25 kg/m2 or greater, central obesity and diabetes mellitus. …”
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The Bioactivities of Phycocyanobilin from Spirulina by Yi Li

“…PCB can resist oxidation by scavenging free radicals, inhibiting the activity of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, and delaying the activity of antioxidant enzymes. In addition, PCB can also be used as an excellent anti-inflammatory agent to reduce the proinflammatory factors IL-6 and IFN-γ and to up-regulate the production of anti-inflammatory cytokine IL-10 by inhibiting the inflammatory signal pathways NF-κB and mitogen-activated protein kinase (MAPK). …”
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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms by Tamás Rőszer

“…These markers are transmembrane glycoproteins, scavenger receptors, enzymes, growth factors, hormones, cytokines, and cytokine receptors with diverse and often yet unexplored functions. …”
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Cell Secretion: Current Structural and Biochemical Insights by Saurabh Trikha, Elizabeth C. Lee, Aleksandar M. Jeremic

“…Essential physiological functions in eukaryotic cells, such as release of hormones and digestive enzymes, neurotransmission, and intercellular signaling, are all achieved by cell secretion. …”
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Hypertrophic Cardiomyopathy Mimicking Acute Anterior Myocardial Infarction Associated with Sudden Cardiac Death by Y. Daralammouri, M. El Garhy, K. Same, B. Lauer

“…The patient presented with acute ST elevation myocardial infarction and significant elevation of cardiac enzymes. Cardiac catheterization showed some atherosclerotic coronary artery disease, without significant stenosis. …”
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Fungal- and Algal-Derived Synthesis of Various Nanoparticles and Their Applications by Anugrah Michael, Aniket Singh, Arpita Roy, Md. Rabiul Islam

“…Greener synthesis through fungus and algae done through bioreduction by biomolecules or enzymes present in them is low-energy, low-cost, and needs a low-temperature environment, providing a unique technique for the manufacture of various metallic nanoparticles utilized in an array of industries and healthcare.…”
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MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma by Changsheng Zhou, Jia Liu, Xudong Hu, Lu Lu, Juan Hou, Jian Wang, Liqun Jiang, Shuangshuang Huang, Yu Lin, Luyao Liu, Lingling Cui, Yiqian Liu, Yufeng Huang

“…Abstract Cholesterol metabolism is abnormally active in tumour cells. Metabolic enzymes related to cholesterol metabolism are upregulated in tumours, but their nonmetabolic functions remain unclear. …”
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Mitochondrial Stress Signaling Promotes Cellular Adaptations by Jayne Alexandra Barbour, Nigel Turner

“…This involves communication of stress to the cell and successful induction of quality control responses, which include mitophagy, unfolded protein response, upregulation of antioxidant and DNA repair enzymes, morphological changes, and if all else fails apoptosis. …”
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Myocardial Infarction in Neonates: A Diagnostic and Therapeutic Challenge by Manuel Rodríguez Martínez, Eladio Ruiz González, Anna Parra-Llorca, Máximo Vento Torres, Marta Aguar Carrascosa

“…An electrocardiogram revealed QS pattern in leads I, aVL, and V6, suggestive of ischemia. Cardiac enzymes were elevated, and echocardiogram revealed moderate left ventricular dysfunction with a thrombus at the level of the left atrial appendage. …”
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PENGARUH PEMBERIAN SARI KULIT NANAS (Ananas comosus (L) Merr) TERHADAP JUMLAH KOLONI BAKTERI PADA IKAN BANDENG (Chanos chanos F.) by Zainal Berlian, Fitratul Aini, Melda Yunita

“…Rind the  pineapple contains bromelain enzymes, citric acid and phenols, to inhibit bacterial growth. …”
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