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3741
In defence of ferroptosis
Published 2025-01-01“…A common thread uniting all key enzymes and metabolites that combat lipid peroxidation during ferroptosis is a dependence on a key cellular reductant, nicotinamide adenine dinucleotide phosphate (NADPH). …”
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3742
A Rare Case of Post-Partum Hemorrhage with Refractory Thrombotic Microangiopathy, and Hepatic Infarction: A Diagnostic Dilemma with High Mortality
Published 2022-12-01“…During her illness, she developed rising liver enzymes and bilirubin, diffuse intravascular coagulation, renal failure, alveolar hemorrhage, and acute fulminant hepatic failure. …”
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3743
Nitrogen, phosphorus, and potassium requirements to improve Sideritis cypria growth, nutrient and water use efficiency in hydroponic cultivation
Published 2025-01-01“…The NPK and the K550 levels caused oxidative stress as demonstrated by the raised lipid peroxidation and the stimulation of enzymes’ antioxidant activities. The P50 levels in the NS, increased the plant biomass and water use efficiency (WUE) and revealed the lower oxidative stress (malondialdehyde) and increased enzymes antioxidant (superoxide dismutase and peroxidase) activities. …”
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3744
Collaborative Effects of Caloric Restriction and Quercetin on Age-related Oxidative Stress Reduction through NQO1/Sirt1 Gene Regulation
Published 2024-12-01“…The activities of catalase (CAT), paraoxonase (PON1), liver enzymes and lipid profiles, and the expression of SIRT1 and NQO1 genes were analyzed using the desired methods. …”
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3745
The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis
Published 2016-01-01“…Comparing changes in study markers following interventions showed improvement in liver enzymes. The levels of triglycerides and cholesterol were significantly reduced in the group treated with Cynara scolymus when compared to placebo group. …”
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3746
Phage-Derived Endolysins Against Resistant Staphylococcus spp.: A Review of Features, Antibacterial Activities, and Recent Applications
Published 2024-11-01“…In recent years, there has been growing interest in using endolysins to combat bacterial infections. These enzymes, which are also referred to as lysins, are a unique class of hydrolytic enzymes synthesized by double-stranded DNA bacteriophages. …”
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3747
Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis.
Published 2024-01-01“…We also identified similarities between MBP and MOG proteins and bile salt hydrolase (BSH), glycosyltransferase (WcfQ), and Wzy enzymes. Identical amino acids between MBP and BSH at the active site, and protected amino acids in MOG aligning with WcfQ and Wzy enzymes were observed. …”
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3748
The effects of ozone pretreatment on the physicochemical, functional, bioactive, textural, and sensory properties of medicinal plants: A comprehensive review
Published 2024-12-01“…Background and aims: Ozone technology is utilized to inactivate enzymes, destroy microorganisms, and preserve and maintain food quality without chemicals as antimicrobial agents. …”
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3749
Collagenolytic activity of conjunctival fluid in healthy people and patients with aseptic ulcer of the cornea of various etiologies
Published 2018-07-01“…<br> <br> <b>Key words:</b> lacrimal fluid, activity of proteolytic enzymes, dry eye syndrome, Sjorgren’s syndrome, corneal aseptic ulcer, diagnosis of progression.…”
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3750
Free radical processes in rat liver in experimental diabetes, malignant growth and their combination
Published 2022-06-01“…At the same time, there was an almost twofold increase in SOD activity, a decrease in catalase activity, and an increase in the ratio of enzymes by 2.8 times. In females, there was no increase in LPO in the liver; there was only a less pronounced increase in SOD activity than in males. …”
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3751
Salmonella enterica Serotype Typhi Bacteremia Complicating Pregnancy in the Third Trimester
Published 2017-01-01“…Typhi should be considered in febrile patients with recent travel presenting with abdominal discomfort with or without elevated liver enzymes.…”
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3752
Zymography of proteases in honey bees (Apis Mellifera) infected with Nosema ceranae
Published 2024-01-01“…Identifying and developing drugs that target these microsporidia without having serious effects on host bee physiology is essential for controlling nosemosis, and this requires information about bee enzymes. Serine proteases, the major protease enzymes in insects, play an important role in the insect immune system. …”
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3753
Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats
Published 2015-01-01“…Further, in hippocampus and frontal cortex, aluminium-induced elevation in nitrite and TNF-α and reduction in antioxidant enzymes were inhibited by simvastatin. Conclusion. …”
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3754
Complete Genome Sequence Analysis of Bacillus subtilis MC4-2 Strain That against Tobacco Black Shank Disease
Published 2024-01-01“…Genomic prediction analysis revealed that a total of 145 genes were annotated by the CAZy, containing mainly GH and CE enzymes that break down carbohydrates such as glucose, chitin, starch, and alginate, and a large number of enzymes involved in glycosylation were present. …”
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3755
Modulation of Second Messenger Signaling in the Brain Through PDE4 and PDE5 Inhibition: Therapeutic Implications for Neurological Disorders
Published 2025-01-01“…Phosphodiesterase (PDE) enzymes regulate intracellular signaling pathways crucial for brain development and the pathophysiology of neurological disorders. …”
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3756
Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets
Published 2025-04-01“…This review provides an in-depth analysis of the complex relationship between lipid metabolic reprogramming and associated ferroptosis in OS from the perspective of metabolic enzymes and metabolites. We discussed the molecular basis of lipid uptake, synthesis, storage, lipolysis, and the tumor microenvironment, as well as their significance in OS development. …”
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3757
Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta
Published 2015-01-01“…Gene expression of enzymes Faah, Mgll, Plcd4, Pld1, Nat1, Daglα, and Ptgs2 was studied (cohort 1, microarray). …”
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3758
Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats
Published 2014-01-01“…Serum levels of hepatic enzymes and TNF-alpha were concomitantly increased during hepatic I/R. …”
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3759
Effect of Different Stages of Chronic Kidney Disease and Renal Replacement Therapies on Oxidant-Antioxidant Balance in Uremic Patients
Published 2013-01-01“…However, the activity of antioxidant enzymes was altered by impaired renal function and by both dialysis treatments.…”
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3760
The Association of Adipokines and Myokines in the Blood of Obese Children and Adolescents with Lipoprotein Lipase rs328 Gene Variants
Published 2023-01-01“…Obesity develops largely due to genetic factors, with the genetic polymorphism of lipid metabolism enzymes being of particular importance. However, it is still unclear how the genetic variants of one of the key enzymes in lipid transport, lipoprotein lipase (LPL), are associated with the endocrine function of mesenchymal tissues in obesity. …”
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