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3721
Theoretical Calculations and Molecular Docking Analysis of 4-(2-(4-Bromophenyl)Hydrazineylidene)-3,5-Diphenyl-4H-Pyrazole Molecule
Published 2024-12-01“…Molecular docking analysis of BHDH molecule on obesity disease was performed with acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. The highest binding energies and binding conformations between ligands and enzymes were predicted.…”
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3722
Differential Sensitivity of Nitrogen-Fixing, <i>Azolla Microphylla</i> to Organochlorine and Organophosphate Insecticide
Published 2013-07-01“…Pesticide treatment with increasing doses accelerated the formation of reactive oxygen species progressively, whereby an enhanced Antioxidant enzymes and metabolites were noticed in A. microphylla. …”
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3723
Current strategic development of single-atom electrocatalyst in sensor construction: A mini-review
Published 2024-12-01“…With the development of advanced catalysts, the assessment of emerging single-atom-based electrochemical catalysts (SAECs) has significantly increased owing to their similarity to natural enzymes. They hold substantial potential for the design and construction of electrochemical sensing platforms. …”
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3724
Aldehyde Dehydrogenases: Not Just Markers, but Functional Regulators of Stem Cells
Published 2019-01-01“…Aldehyde dehydrogenase (ALDH) is a superfamily of enzymes that detoxify a variety of endogenous and exogenous aldehydes and are required for the biosynthesis of retinoic acid (RA) and other molecular regulators of cellular function. …”
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3725
The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth
Published 2013-01-01“…Since inflammation is the prerequisite for gingival overgrowth, mast cells and its protease enzymes also play a vital role in the pathogenesis of gingival fibrosis. …”
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3726
Differential Sensitivity of Nitrogen-Fixing, <i>Azolla Microphylla</i> to Organochlorine and Organophosphate Insecticide
Published 2013-07-01“…Pesticide treatment with increasing doses accelerated the formation of reactive oxygen species progressively, whereby an enhanced Antioxidant enzymes and metabolites were noticed in A. microphylla. …”
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3727
Investigating the Biological Impact of Melatonin on Male Albino Mice: A Comprehensive Characterization
Published 2025-01-01“…The aim of this study was to see how Mel generated from Ziziphus spina-christi leaves affected thyroid, liver enzymes, and lipid profiles in male albino mice. Twenty male mice were divided into four groups, each containing five mice, and were administered intraperitoneally (i.p) injections of Mel in three doses (4, 7 and 10 mg/ml), except for the control group, which received only a dose of normal saline solution. …”
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3728
Subcapsular hepatic hematoma. Serious complication during pregnancy
Published 2010-12-01“…Subcapsular hepatic hematoma is a rare complication during pregnancy, but potentially lethal and usually related to severe pre-eclampsia or HELLP syndrome (hemolysis, elevated liver enzymes and diminished platelets). Maternal and perinatal mortality in these cases is high, hence the importance of early diagnosis and timely and multidisciplinary treatment. …”
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3729
A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
Published 2024-11-01“…Recent studies evidenced the key role of gene duplications in the over-expression of detoxification enzymes and their potential use to track metabolic resistance alleles in the field. …”
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3730
Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium
Published 2023-12-01“…Within this set, 47 are assumed to be regulators of gene expression, governing the transcription of enzymes pivotal to the metabolic cascade. Complementing this, an additional assembly of 35 regulators are considered to be regulators of activity, degradation, and translocation dynamics of enzymes integral to the aforementioned pathway. …”
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3731
Spinal Antinociceptive Action of Amiloride and Its Interaction with Tizanidine in the Rat Formalin Test
Published 2015-01-01“…BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes. Intrathecal α2-adrenergic receptor agonists produce pronounced analgesia, and amiloride modulates α2-adrenergic receptor agonist binding and function, acting via the allosteric site on the α2A-adrenergic receptor.…”
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3732
Hydrogenases – Types, Sources, Properties, and the Potential for Their Application
Published 2025-01-01“…They are explored mostly from the biochemical point of view, which is very important, but there is a lack of research on how to adapt these enzymes for real industrial-scale processes. Only a few studies address this gap. …”
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3733
Transcriptome responses to Ralstonia solanacearum infection in tetraploid potato
Published 2025-01-01“…By demonstrating the importance of enzymes and differential gene expression in Huashu No. 12 resistance to R. solanacearum infection, the breeding of disease-resistant potato becomes increasingly feasible.…”
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3734
Lamotrigine-Valproic Acid Interaction Leading to Stevens–Johnson Syndrome
Published 2018-01-01“…VPA can cause inhibition of epoxide hydrolase enzymes and/or depletion of glutathione levels leading to adverse cutaneous reactions.…”
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3735
Study on the response mechanism of MicroRNA novel-13 and novel-44 to Vibrio parahaemolyticus infection in Pinctada fucata martensii
Published 2025-01-01“…The activity of antioxidant-related enzymes increased significantly in the synthetic miRNA (novel-13 and novel-44) inhibitors and decreased significantly in the synthetic miRNA mimics. …”
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3736
Effects of typical plant growth regulator chlormequat chloride on alkaloidal compounds in Corydalis yanhusuo and molecular mechanisms
Published 2025-01-01“…Transcriptomic analysis also facilitates the identification of differential genes and enzymes associated with alkaloid production between the two groups. …”
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3737
Unveiling the Mechanisms for Decreased Glutathione in Individuals with HIV Infection
Published 2012-01-01“…We observed decreased expression of the genes coding for enzymes responsible for de novo synthesis of GSH in macrophages derived from HIV+ subjects using quantitative PCR (qPCR). …”
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3738
CHI-KAT8i5 suppresses ESCC tumor growth by inhibiting KAT8-mediated c-Myc stability
Published 2025-01-01“…Summary: The integrated analysis of histone modifier enzymes in solid tumors, especially in esophageal squamous cell carcinoma (ESCC), is still inadequate. …”
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3739
De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses
Published 2018-01-01“…Interestingly, the S. latifolia genome encodes most enzymes involved in carbohydrate and glycoconjugate metabolism and is also enriched in genes encoding enzymes critical to secondary metabolite biosynthesis and involved in indole, terpene, and type I polyketide pathways. …”
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3740
Evaluating the Biodeterioration Enzymatic Activities of Fungal Contamination Isolated from Some Ancient Yemeni Mummies Preserved in the National Museum
Published 2014-01-01“…Five of these mummies were used to evaluate hydrolytic enzymes produced as a result of fungal contamination. …”
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