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3681
Nb-FAR-1: A key developmental protein affects lipid droplet accumulation and cuticle formation in Nippostrongylus brasiliensis.
Published 2025-01-01“…The offspring L3s in Nb-far-1 RNAi group had a reduction in lipid droplets within the subcuticle and the swelling of the perioral epidermis, accompanied with down-regulated expression of enzymes in amino acid and glycerolipid metabolism and glycometabolism for growth by RNA-seq data. …”
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3682
Expression of palmitoyl transferases in brain structures of mice genetically predisposed to depressive-like behavior
Published 2018-08-01“…Among these modifications is S-palmitoylation, carried out by specialized enzymes palmitoyl transferases. Palmitoylation is the covalent attachment of a long-chain fatty acid, palmitate, to cysteine residues. …”
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3683
Comparative lipidome and transcriptome provide novel insights into zero-valent iron nanoparticle-treated Fremyella diplosiphon
Published 2024-11-01“…While the expression of iron uptake and ion channel genes was downregulated, genes coding for photosynthesis, pigment, and antioxidant enzymes were significantly (p < 0.05) upregulated in B481-SD treated with 3.2 mg L−1 nZVIs compared to the untreated control. …”
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3684
The Predictive Role of Parathyroid Hormone for Nonalcoholic Fatty Liver Disease following Bariatric Surgery
Published 2022-01-01“…A significant reduction was observed in the anthropometric parameters, liver enzymes, and hepatic elasticity after bariatric surgery. …”
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3685
Isolation, characterization and control of Botrytis spp. pathogenic on strawberry in Iran
Published 2025-01-01“…This EO reduced the activity of cell wall degrading enzymes, such as cellulase and pectinase produced by both fungal species. …”
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3686
Effect of Supplementation with Bacillus subtilis in the Diet of Pigs on Protein and Lipid Oxidation of Pork Stored in High-oxygen Modified Atmosphere Packaging
Published 2025-01-01“…Following slaughter, the longissimus dorsi muscle was taken and cut into two parts: one part was used to measure the activity of antioxidant enzymes; the other part was packaged under high oxygen conditions and stored at 4 ℃. …”
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3687
Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs
Published 2025-02-01“…Simultaneously, miRNAs can regulate DNA methylation levels by targeting key enzymes such as DNA methyltransferases (DNMTs), thereby establishing a complex feedback regulatory network. …”
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3688
Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma
Published 2021-01-01“…In cancer tissues, the expression levels of enzymes related to glycolysis, pentose phosphate pathway (PPP), and fatty acid (FA) synthesis were increased and that of tricarboxylic acid (TCA) cycle and β-oxidation were suppressed. …”
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3689
Feruloyl-amides as natural antimicrobials for crop and food protection
Published 2025-01-01“…The main mechanism of defence is based on a rapid transcriptional reprogramming of genes encoding biosynthetic enzymes that synthesize specific secondary metabolites. …”
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3690
Characteristics and bioinformatics of peptides from natural and cultured sandfish (Holothuria scabra)
Published 2025-06-01“…LC-MSMS analysis, coupled with bioinformatics database comparisons, indicated that sandfish from natural and cultured sources, as well as different enzymes used in the hydrolysis process, significantly affect protein and peptide pattern. …”
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3691
Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury
Published 2025-01-01“…Upon reperfusion, intestinal hypoxia may persist because microcirculatory flow remains impaired and/or because available oxygen is consumed by enzymes, intestinal cells and neutrophils.…”
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3692
Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE2-EP2 mediated microglia-neuron signaling
Published 2025-06-01“…Neurosteroid allopregnanolone is suggested to modulate the expression of various receptors or enzymes that involved in pain perception, presenting an analgesic potential. …”
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3693
Comprehensive identification, characterization and expression analyses of the class III POD gene family in water lily (Nymphaea colorata)
Published 2025-01-01“…Finally, the RT-qPCR based expression and enzymes activity of ten NcPOD genes depicted the dynamically differential response to NaCl, heat, cold, and heavy metals (CuSO4 and CdCl2) stresses. …”
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3694
Direct and Indirect Protein Interactions Link FUS Aggregation to Histone Post-Translational Modification Dysregulation and Growth Suppression in an ALS/FTD Yeast Model
Published 2025-01-01“…We show that the histone-modifying enzymes Ipl1 and Rtt109—responsible for installing H3S10ph and H3K56ac—are excluded from the nucleus in the context of FUS proteinopathy. …”
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3695
Phenolic acids from Anisopus mannii modulates phosphofructokinase 1 to improve glycemic control in patients with type 2 diabetes: A double-blind, randomized, clinical trial
Published 2025-02-01“…Among other glycolytic enzymes, in vitro, PhAM counteracted the binding of sodium orthovanadate to phosphofructokinase 1 (PFK-1), improving its activities. …”
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3696
Bionic nanovesicles sequentially treat flaps with different durations of ischemia by thrombolysis and prevention of ischemia-reperfusion injury
Published 2025-04-01“…Specifically, we have successfully constructed a clinical-grade bionic vesicle, UK-PBNZ@PM, a system that cleverly incorporates drug components that have been widely used in clinical applications, thereby demonstrating a high degree of clinical translational potential. Prussian blue nano-enzymes (PBNZ) are the core component and demonstrate remarkable efficacy against ischemia-reperfusion injury due to their excellent biocompatibility, robust reactive oxygen species (ROS) scavenging capacity and anti-inflammatory properties. …”
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3697
Carbon Dioxide Micro-Nano Bubbles Aeration Improves Carbon Fixation Efficiency for Succinic Acid Synthesis by <i>Escherichia coli</i>
Published 2025-01-01“…The activities of key enzymes within the SA synthesis pathway were also maintained or enhanced in the fermentation process with MNB aeration. …”
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3698
Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice
Published 2013-01-01“…Levels of serum liver enzymes and histopathology were determined. Levels of inflammatory cytokines with ConA-induced hepatitis were determined with real-time polymerase chain reaction (real-time PCR). …”
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3699
Genome-Wide Identification of Superoxide Dismutase (<i>SOD</i>) Gene Family in <i>Cymbidium</i> Species and Functional Analysis of <i>CsSOD</i>s Under Salt Stress in <i>Cymbidium s...
Published 2025-01-01“…Superoxide dismutase (SOD) enzymes are essential for reducing oxidative damage resulting from overabundant reactive oxygen species under abiotic stress. …”
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3700
Investigating the response mechanisms of the intertidal seagrass Zostera japonica to increased UVB radiation through physiological, transcriptomic, and metabolomic analyses
Published 2025-02-01“…To mitigate these adverse effects, the expression levels of genes related to antioxidants and UV-absorbing compounds, including flavonoids (PAL, 4CL, CHS, CHI, F3H) and antioxidant enzymes (DHAR, MDHAR, APX), were upregulated. The increased synthesis of these compounds serves to scavenge accumulated ROS and absorb UV radiation. …”
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