L-selenomethionine inhibits small intestinal ferroptosis caused by ammonia exposure through regulating ROS-mediated iron metabolism by Xinxin Zhang, Lepeng Gu, Ying Chen, Tianqi Wang, Houjuan Xing

“…The results showed that ammonia exposure up-regulated the levels of iron, ROS, MDA, and LPO in the small intestinal tissue and the IPEC-J2 cell, down-regulated the activities of antioxidant enzymes and the content of GSH, inhibited the Nrf2 pathway, significantly altered the expression of ferroptosis (TFR-1, FPN-1, FTH1, SLC7A11, GPX4, ACSL4) and intestine tight junctions (Claudin-1, Occludin, ZO-1) genes. …”
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Enhancing the efficacy of low doses of N-acetyl-L-cysteine in mitigating CCl4-induced hepatotoxicity in animal model using physical cold plasma by Masume Farhadi, Farshad Sohbatzadeh, Akbar Hajizadeh Moghaddam, Yasaman Firouzjaei, Cheng Cheng

“…Also, the antioxidant enzymes and oxidative stress activities improved after receiving PTN. …”
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Liraglutide Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism via SHP1/AMPK Signaling Pathway by Peng Yu, Xi Xu, Jing Zhang, Xuan Xia, Fen Xu, Jianping Weng, Xiaoyang Lai, Yunfeng Shen

“…LR administration significantly lowered the serum lipid profile and lipid disposition in vitro and in vivo because of the altered expression of enzymes on hepatic gluconeogenesis and lipid metabolism. …”
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Immunization of cattle with a Rhipicephalus microplus chitinase peptide containing predicted B-cell epitopes reduces tick biological fitness by María Martina Esperanza Perez-Soria, Daniel Gustavo López-Díaz, Rafael Jiménez-Ocampo, Gabriela Aguilar-Tipacamú, Massaro W. Ueti, Juan Mosqueda, Ala Tabor

“…To develop novel tick vaccines, it is crucial to identify and evaluate antigens capable of generating protection in cattle. Chitinases are enzymes that degrade older chitin at the time of moulting, therefore allowing interstadial metamorphosis. …”
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Selenium’s Role in Plant Secondary Metabolism: Regulation and Mechanistic Insights by Yan Zhou, Kaiqin Nie, Lulu Geng, Yixin Wang, Linling Li, Hua Cheng

“…Although it has been shown that selenium can affect the antioxidant system and defense mechanisms in plants, detailed mechanisms of selenium’s action on plant secondary metabolic pathways, including its effects on specific metabolic enzymes and regulatory genes, still need to be revealed by further in-depth studies. …”
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Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion by Katsuya Sakimura, Tatsuya Maekawa, Shin-ichi Kume, Takeshi Ohta

“…To get an insight into the mechanism underlying the impaired melatonin secretion in SDT fatty rats, the expression of arylalkylamine N-acetyltransferase (Aanat) and acetylserotonin O-methyltransferase (Asmt) mRNA, which encode the rate-limiting enzymes for melatonin synthesis, was investigated in the pineal gland. …”
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Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats by Igor Y. Iskusnykh, Tatyana N. Popova, Aleksander A. Agarkov, Miguel Â. A. Pinheiro de Carvalho, Stanislav G. Rjevskiy

“…It can be proposed that the overexpression of these enzymes could be a mechanism of enhancement of hepatocytes tolerance to oxidative stress.…”
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Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines by Edismauro Garcia Freitas Filho, Elaine Zayas Marcelino da Silva, Camila Ziliotto Zanotto, Constance Oliver, Maria Célia Jamur

“…The effect of cross-linking these gangliosides on the activation of enzymes in the arachidonate cascade was then investigated. …”
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The adaptation of rainbow trout to warmer water: Oxidative damage in the germinal line by Vianel Sevastei, Sonia A. Crichigno, M. Victoria Santos, Andrea Trochine, Julio C. Painefilú, Noemí Zaritzky, Víctor E. Cussac

“…We examined: Oxidative damage (lipid peroxidation) and activities of antioxidant enzymes; Catalase (CAT), Glutathione S-Transferases (GST), and Superoxide Dismutase (SOD), in liver, testicle, and spermatozoa. …”
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Effects of aluminum on metabolism of reactive oxygen species and reactive nitrogen species in root tips of different Eucalyptus species by Zilong Ouyang, Bing Liu, Tangkan Li, Tiandao Bai, Weichao Teng

“…By observing the occurrence and distribution of the main reactive oxygen species (ROS) and reactive nitrogen species (RNS) in root tips of Eucalyptus seedlings under Al stress, this study analyzed change in the growth and physiological indexes of Eucalyptus seedlings under Al stress. The antioxidant enzymes activities of the root tips of different Eucalyptus species induced by Al stress resulted in different ROS and RNS contents, ultimately resulting in differing degrees of membrane lipid peroxidation. …”
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Colada morada, a traditional Ecuadorian Day of the dead beverage: Bibliometric analysis and review of the biological activity of native Ecuadorian ingredients by Juan Carlos Romero-Benavides, Rodrigo Duarte-Casar, Marlene Rojas-Le-Fort, Natalia Bailon-Moscoso

“…Using bibliometric analysis and document reviews, we identified major bioactive compounds such as phenolic acids, anthocyanins, flavonoids, terpenoids, and proteolytic enzymes, which exhibit antioxidant, antimicrobial, anti-inflammatory, and chemopreventive properties. …”
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How Antiretroviral Drug Concentrations Could Be Affected by Oxidative Stress, Physical Capacities and Genetics: A Focus on Dolutegravir Treated Male PLWH by Jessica Cusato, Anna Mulasso, Micol Ferrara, Alessandra Manca, Guido Accardo, Alice Palermiti, Miriam Antonucci, Gianluca Bianco, Francesco Chiara, Jacopo Mula, Maria Cristina Tettoni, Simone Cuomo, Giulia Trevisan, Stefano Bonora, Giovanni Di Perri, Corrado Lupo, Alberto Rainoldi, Antonio D’Avolio

“…ROS influence the expression of gene-encoding enzymes and transporters involved in drug biotransformation. …”
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Cardiometabolic Risk in Hyperlipidemic Men and Women by Michael Leutner, Christian Göbl, Alice Wielandner, Eleonora Howorka, Marlies Prünner, Latife Bozkurt, Jürgen Harreiter, Helmut Prosch, Oliver Schlager, Silvia Charwat-Resl, Alexandra Kautzky-Willer

“…HL-women were older and had overall more favourable concentrations of lipid parameters and liver enzymes but did not differ regarding vascular morphology and insulin sensitivity compared to HL-men of comparable body mass index (BMI).…”
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Impact of a Carvacrol Treatment on Post-Harvest Ripening Quality and Cell Wall Metabolism in the Kiwifruit by Donglan Luo, Xiaogang Wang, Tingting Mi, Jianye Chen, Liangjie Ba, Sen Cao

“…A correlation analysis shows that firmness is highly and negatively correlated with the cell wall degrading enzymes PG, PME, β-Gal, Cx, and α-L-Af, with R values of −0.88, −0.83, −0.98, −0.94, and −0.93, respectively. …”
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Protein hydrolysates of niosome-encapsulated skipjack (Katsuwonus pelamis) viscera: Antioxidant, anticancer, and release properties by Shima Kaveh, Alireza Sadeghi Mahoonak, Vahid Erfani-Moghadam, Mohammad Ghorbani, Aliakbar Gholamhosseinpour, Mojtaba Raeisi

“…So, this study aimed to produce skipjack viscera protein hydrolysates (FPH) using different enzymes (pancreatin, alcalase, trypsin, and pepsin) at different hydrolysis times. …”
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Eco-Friendly Extraction of Phlorotannins from <i>Padina pavonica</i>: Identification Related to Purification Methods Towards Innovative Cosmetic Applications by Moustapha Nour, Valérie Stiger-Pouvreau, Alain Guenneguez, Laurence Meslet-Cladière, Stéphane Cérantola, Ahmed Ali, Gaelle Simon, Abdourahman Daher, Sylvain Petek

“…All fractions were also evaluated for their anti-ageing potential by assessing their ability to inhibit two vital skin-ageing enzymes, tyrosinase and elastase. Structural analysis by ¹H-¹³C HMBC NMR and LC-MS revealed a selectivity of phlorotannins depending on the purification methods. …”
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A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide by Angelo Santoro, Antonio Ricci, Manuela Rodriquez, Michela Buonocore, Anna Maria D’Ursi

“…Antioxidants like curcumin, a derivative of Curcuma longa, help mitigate ER stress by scavenging ROS and enhancing antioxidant enzymes. Furthermore, evidence in the literature highlights the effect of curcumin on the secondary structure of Aβ(1–42). …”
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Recovery of Prenatal Baicalein Exposure Perturbed Reproduction by Postnatal Exposure of Testosterone in Male Mice by Sridevi Vaadala, Naveen Ponneri, Venkata Shashank Karanam, Sri Bhashyam Sainath, Pamanji Sreenivasuala Reddy, Ramachandra Reddy Pamuru, Arifullah Mohammed

“…A downward trend was observed in testicular steroidogenic marker enzymes (3β- and 17β-steroid dehydrogenases) and serum testosterone, whereas increase in serum titers of FSH and LH along with altered the testicular histology. …”
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CRISPR-based epigenetic editing of Gad1 improves synaptic inhibition and cognitive behavior in a Tauopathy mouse model by Lei Wan, Ping Zhong, Pei Li, Yong Ren, Wei Wang, Mingjun Yu, Henry Y. Feng, Zhen Yan

“…We confirmed that GABA synthesizing enzymes, GAD1 and GAD2, were significantly downregulated in prefrontal cortex (PFC) of AD human postmortem tissues. …”
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Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells by Ping-Ho Chen, Yaw-Syan Fu, Yun-Ming Wang, Kun-Han Yang, Danny Ling Wang, Bin Huang

“…Therefore, NO did not reciprocally increase the expression of H2S-generating enzymes and the H2S level. The present study provides an integrated insight of cellular responses to H2S and NO from protein expression to gaseous molecule generation, which indicates the upstream role of H2S in modulating NO production and protein S-nitrosylation.…”
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